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The map label for this gene is ctaD [H]

Identifier: 218531518

GI number: 218531518

Start: 3774248

End: 3775876

Strand: Reverse

Name: ctaD [H]

Synonym: Mchl_3586

Alternate gene names: 218531518

Gene position: 3775876-3774248 (Counterclockwise)

Preceding gene: 218531519

Following gene: 218531517

Centisome position: 65.35

GC content: 64.95

Gene sequence:

>1629_bases
ATGGCCACCGCCACAGCACATGCCGGGCATGACGCCCACCACGACCACAAGCCCTCCTTCTTCTCCCGCTGGTTCCTCTC
GACGAACCACAAGGACATCGGCACGCTCTACCTGATCTTCGCCTTCATGGCGGGCATCATCGGTGCGTTCCTGTCCTTCG
GCATCCGCATGGAGATGGAGGAGCCTGGGCTCCAGTACTTCTCCAACCCGGCGACCTACAACGTGTTCGTCACCGGCCAC
GGCCTCATCATGGTGTTCTTCATGGTGATGCCCGCCCTCATCGGCGGCTTCGGCAACTGGTTCGTCCCGCTGATGATCGG
CGCGCCGGACATGGCCTTCCCGCGGATGAACAACGTCTCGTTCTGGCTGACGGTGTCGGGCTTCGCCTGCCTCCTCTGCT
CGCTGTTCGTCGAGGGTTCGCCCGGCGCCACCGGCGCGGGCACCGGCTGGACCGTCTACCCGCCGCTGTCCTCCTCGGCC
GGCCATCCCGGCCCGGCGGTCGATTTCGCGATCTTCTCGCTCCACCTCGCCGGTGCGGGCTCGATCCTCGGCGCGATCAA
CTTCATCACCACCATCCTCAACATGCGCGCCCCCGGCATGACGCTGCACAAGATGCCGCTCTTCGCCTGGGCCGAGCTCG
TCACCGCCTTCCTGCTGCTCCTGTCGCTCCCGGTTCTGGCCGGTGCGATCACGATGCTGCTCACCGACCGTAACTTCGGC
ACCACCTTCTTCGCCCCCGAGGGCGGCGGCGATCCGGTGCTCTACCAGCACCTGTTCTGGTTCTTCGGTCACCCCGAAGT
GTACGTGATGATCCTGCCGGCCTTCGGCATCGTCTCGCACATCATCGCCACCTTCTCGCGCAAGCCCGTCTTCGGCTACC
TCGCCATGGCCTACGCCATGGTCGCCATCGGCGTCGTCGGCTTCGTCGTGTGGGCCCACCACATGTACACCGTCGGCCTG
TCGCTCCAGACGCAGTCCTACTTCGTCTTCGCGACCATGGTGATCGCGGTGCCGACCGGCGTGAAGATCTTCTCCTGGAT
CGCGACGATGTGGGGCGGTTCGATCCGCTTCACCGCGGCGATGCACTGGGCTGTGGGCTTCATCTTCCTGTTCACGGTCG
GCGGCGTCACCGGCGTCGTGCTCGCGAACTCCTCGGTCGATAAGTACCTGCACGACACCTACTATGTCGTGGCGCACTTC
CACTACGTGCTCTCGCTCGGTGCCGTGTTCATCATCTTCGCCGGTATCTACTACTGGTTCCCGAAGATGACCGGCCACGT
CATCCCGGAATGGGCGGGCAAGCTGCACTTCTGGCTGGCCTTCATCGGCGCGAACGTCCTGTTCTTCCCGATGCACTTCC
TGGGTCTGGCCGGCATGCCGCGTCGCTACGCCGACTATCCCGAGGCCTTCGCCGGCTGGCACAAGGTCGCGACGCTGGGC
GGTCACGTCTTCGCCCTCAGCATGATCGTCTTCGTGATCGGCATCGTGCTGGCCTTCCGCTCCAAGACCCGCGCCGCGGA
CAATCCGTGGGGCGAGGGTGCCACCACCCTGGAATGGACCCTCTCCTCGCCCCCGCCCTTCCACCAGTTCGAGACGCTCC
CGAAGATCGTCGACGAGCCGGCCCACTAA

Upstream 100 bases:

>100_bases
CGCGCCTCGCGGACGCCCGCTGACGCTTCTCCGGGCCGGCACGCGCCGGCCGGATCTCCCTTCGCCAGAGGCGACAGACA
TCTGATTAAGGCAAGGATCG

Downstream 100 bases:

>100_bases
GGGCGGGACGAAAACCGAAGATCGCGAGGACCGCCCCGGCGGTCCTCGCTCTTTCCCGGAGGCCTCTCACCGCTAAGGCG
AGGCCTCCCGCAAAGGGCGG

Product: cytochrome C oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MATATAHAGHDAHHDHKPSFFSRWFLSTNHKDIGTLYLIFAFMAGIIGAFLSFGIRMEMEEPGLQYFSNPATYNVFVTGH
GLIMVFFMVMPALIGGFGNWFVPLMIGAPDMAFPRMNNVSFWLTVSGFACLLCSLFVEGSPGATGAGTGWTVYPPLSSSA
GHPGPAVDFAIFSLHLAGAGSILGAINFITTILNMRAPGMTLHKMPLFAWAELVTAFLLLLSLPVLAGAITMLLTDRNFG
TTFFAPEGGGDPVLYQHLFWFFGHPEVYVMILPAFGIVSHIIATFSRKPVFGYLAMAYAMVAIGVVGFVVWAHHMYTVGL
SLQTQSYFVFATMVIAVPTGVKIFSWIATMWGGSIRFTAAMHWAVGFIFLFTVGGVTGVVLANSSVDKYLHDTYYVVAHF
HYVLSLGAVFIIFAGIYYWFPKMTGHVIPEWAGKLHFWLAFIGANVLFFPMHFLGLAGMPRRYADYPEAFAGWHKVATLG
GHVFALSMIVFVIGIVLAFRSKTRAADNPWGEGATTLEWTLSSPPPFHQFETLPKIVDEPAH

Sequences:

>Translated_542_residues
MATATAHAGHDAHHDHKPSFFSRWFLSTNHKDIGTLYLIFAFMAGIIGAFLSFGIRMEMEEPGLQYFSNPATYNVFVTGH
GLIMVFFMVMPALIGGFGNWFVPLMIGAPDMAFPRMNNVSFWLTVSGFACLLCSLFVEGSPGATGAGTGWTVYPPLSSSA
GHPGPAVDFAIFSLHLAGAGSILGAINFITTILNMRAPGMTLHKMPLFAWAELVTAFLLLLSLPVLAGAITMLLTDRNFG
TTFFAPEGGGDPVLYQHLFWFFGHPEVYVMILPAFGIVSHIIATFSRKPVFGYLAMAYAMVAIGVVGFVVWAHHMYTVGL
SLQTQSYFVFATMVIAVPTGVKIFSWIATMWGGSIRFTAAMHWAVGFIFLFTVGGVTGVVLANSSVDKYLHDTYYVVAHF
HYVLSLGAVFIIFAGIYYWFPKMTGHVIPEWAGKLHFWLAFIGANVLFFPMHFLGLAGMPRRYADYPEAFAGWHKVATLG
GHVFALSMIVFVIGIVLAFRSKTRAADNPWGEGATTLEWTLSSPPPFHQFETLPKIVDEPAH
>Mature_541_residues
ATATAHAGHDAHHDHKPSFFSRWFLSTNHKDIGTLYLIFAFMAGIIGAFLSFGIRMEMEEPGLQYFSNPATYNVFVTGHG
LIMVFFMVMPALIGGFGNWFVPLMIGAPDMAFPRMNNVSFWLTVSGFACLLCSLFVEGSPGATGAGTGWTVYPPLSSSAG
HPGPAVDFAIFSLHLAGAGSILGAINFITTILNMRAPGMTLHKMPLFAWAELVTAFLLLLSLPVLAGAITMLLTDRNFGT
TFFAPEGGGDPVLYQHLFWFFGHPEVYVMILPAFGIVSHIIATFSRKPVFGYLAMAYAMVAIGVVGFVVWAHHMYTVGLS
LQTQSYFVFATMVIAVPTGVKIFSWIATMWGGSIRFTAAMHWAVGFIFLFTVGGVTGVVLANSSVDKYLHDTYYVVAHFH
YVLSLGAVFIIFAGIYYWFPKMTGHVIPEWAGKLHFWLAFIGANVLFFPMHFLGLAGMPRRYADYPEAFAGWHKVATLGG
HVFALSMIVFVIGIVLAFRSKTRAADNPWGEGATTLEWTLSSPPPFHQFETLPKIVDEPAH

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=515, Percent_Identity=59.2233009708738, Blast_Score=587, Evalue=1e-168,
Organism=Escherichia coli, GI1786634, Length=528, Percent_Identity=43.3712121212121, Blast_Score=407, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6226519, Length=532, Percent_Identity=56.203007518797, Blast_Score=591, Evalue=1e-169,
Organism=Saccharomyces cerevisiae, GI6226524, Length=327, Percent_Identity=60.8562691131498, Blast_Score=412, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6226523, Length=256, Percent_Identity=55.46875, Blast_Score=269, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59401; Mature: 59270

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATATAHAGHDAHHDHKPSFFSRWFLSTNHKDIGTLYLIFAFMAGIIGAFLSFGIRMEME
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
EPGLQYFSNPATYNVFVTGHGLIMVFFMVMPALIGGFGNWFVPLMIGAPDMAFPRMNNVS
CCCHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCEEEHEECCCCCCCCCCCCEE
FWLTVSGFACLLCSLFVEGSPGATGAGTGWTVYPPLSSSAGHPGPAVDFAIFSLHLAGAG
EEEEHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCCCH
SILGAINFITTILNMRAPGMTLHKMPLFAWAELVTAFLLLLSLPVLAGAITMLLTDRNFG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
TTFFAPEGGGDPVLYQHLFWFFGHPEVYVMILPAFGIVSHIIATFSRKPVFGYLAMAYAM
CEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHH
VAIGVVGFVVWAHHMYTVGLSLQTQSYFVFATMVIAVPTGVKIFSWIATMWGGSIRFTAA
HHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEHHH
MHWAVGFIFLFTVGGVTGVVLANSSVDKYLHDTYYVVAHFHYVLSLGAVFIIFAGIYYWF
HHHHHHHHHHHHHCCHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PKMTGHVIPEWAGKLHFWLAFIGANVLFFPMHFLGLAGMPRRYADYPEAFAGWHKVATLG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHC
GHVFALSMIVFVIGIVLAFRSKTRAADNPWGEGATTLEWTLSSPPPFHQFETLPKIVDEP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCC
AH
CC
>Mature Secondary Structure 
ATATAHAGHDAHHDHKPSFFSRWFLSTNHKDIGTLYLIFAFMAGIIGAFLSFGIRMEME
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
EPGLQYFSNPATYNVFVTGHGLIMVFFMVMPALIGGFGNWFVPLMIGAPDMAFPRMNNVS
CCCHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCEEEHEECCCCCCCCCCCCEE
FWLTVSGFACLLCSLFVEGSPGATGAGTGWTVYPPLSSSAGHPGPAVDFAIFSLHLAGAG
EEEEHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCCCH
SILGAINFITTILNMRAPGMTLHKMPLFAWAELVTAFLLLLSLPVLAGAITMLLTDRNFG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
TTFFAPEGGGDPVLYQHLFWFFGHPEVYVMILPAFGIVSHIIATFSRKPVFGYLAMAYAM
CEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHH
VAIGVVGFVVWAHHMYTVGLSLQTQSYFVFATMVIAVPTGVKIFSWIATMWGGSIRFTAA
HHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEHHH
MHWAVGFIFLFTVGGVTGVVLANSSVDKYLHDTYYVVAHFHYVLSLGAVFIIFAGIYYWF
HHHHHHHHHHHHHCCHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PKMTGHVIPEWAGKLHFWLAFIGANVLFFPMHFLGLAGMPRRYADYPEAFAGWHKVATLG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHC
GHVFALSMIVFVIGIVLAFRSKTRAADNPWGEGATTLEWTLSSPPPFHQFETLPKIVDEP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCC
AH
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]