Click here to switch to the map view.

The map label for this gene is intZ [H]

Identifier: 218531328

GI number: 218531328

Start: 3579148

End: 3580392

Strand: Reverse

Name: intZ [H]

Synonym: Mchl_3396

Alternate gene names: 218531328

Gene position: 3580392-3579148 (Counterclockwise)

Preceding gene: 218531332

Following gene: 218531327

Centisome position: 61.97

GC content: 66.18

Gene sequence:

>1245_bases
GTGGCTGTTCTGACCGCGCGGGCCGTCGAGCTTGCGAAGCCTGATCCGGGCAAGCGCCGAGAGGTTCCGGATGCTGCGCT
TCCTGGACTCTATCTCGTGGTGCAACCGGCCGGCGGGAAGTCGTGGGCCGTGCGCTACCGGGCCGCTGGCAAGCCCCGGA
AACTGACGCTCGGCCCCTATCCACGCCTTGGGCTAGCGGATGCGAGAGAGGCAGCCCGCACCGCTTTGCATGCCGTCGCA
GAGGGCCGTGACCCGGCCGGAGAAAAGCAGGCGGCGAGGGTCGAGGTTGCGGCCGTTCAGACCATGCGATTCGGCGCGGT
GGCGGCGGATTACATCGAGCGGTACGCCAAGCCTCGAAATCGGAGTTGGCGCGAAACCGAAAGCTTCCTCACGCGCACGC
TGGACGCCACGGACAAGTGGCAGGAGAAGGACGTCCGGGCGATCGGCCGCAAGGATGTGCGCGACGCGCTGGATGCTGTG
GTGGCGCGAGGCGCCAGCATTCACGCGAATCGCCTCTTTGCCGCGCTCCGGCGGTTCTTCGCCTGGACGGTTGAGCGCGG
CATCTTGGATGCCTCACCGATGGCTGGCCTGAAGCCGCCCTCCCCTGAGATCTCACGCGACCGCGTTCTGACGGATGCCG
AGCTCGTTGCAGTTTGGAAGGCTGCCGGCGAGGTCGGTTACCCATTCGGGCCGGTGGTCCAATTGCTGATCCTGACCGGG
CAGCGCCGCTCCGAGGTGGTGGAGGCTGAGTGGCGCGAGTTCGATCTTGATGGCGCGACTTGGACGATCCCGCGGGAGCG
CGCGAAAAATGACCGCGCTCATGTCGTGCCCCTGGCGCCGCAAGCGGTGAAGATCCTGAGGTGCATCCCTTGCGTCGGGA
CCCGCTCCCGACTGCTGTTCACCACCACGGGCGAAACTGCGTTTTCCGGCGTCTCTAAGGCTACCGATCGGCTCCAAGGC
TTGTCGGCGAAGCATCTGCCGGAAGGCATCGAGGTCGAGCCCTGGCGGCTGCATGATCTCCGCCGGACGTTCGCCAGCGG
TTGCGCTCGTCTCGGGGTAGCGGTCCACGTCGTGGAGAAAGCACTGAACCACGTCAGCGGCACTCACAGCGGCATCGTCG
GCGTCTATCAAAGGCACAGCTACGGAGATGAGCGCCGCTGCGCCATGGAACTGTGGGCTGCTCACTTGGACGGTCTGGTG
GGTGGCGCTGCGAAGGTGGTCAAGCTGGAGCGGCGGGTGTCATGA

Upstream 100 bases:

>100_bases
TAACGTCCGAAGCCGCCGCTTCTCTGCTACCCCAGCGTTACCCCGGTTACCCACGGATTGAGGGGTAACGGGTCCGATCG
GGTAGCCGCTGGGGGTAACG

Downstream 100 bases:

>100_bases
AGGTCGCAGCAAAGCGCGTCATGAAAGAGTTCCATGACATGGAAGCGCATCAGTTTACCCCAGAACAAATAGAAAGGCTT
GGATTTCTCCCTAAGTTACA

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MAVLTARAVELAKPDPGKRREVPDAALPGLYLVVQPAGGKSWAVRYRAAGKPRKLTLGPYPRLGLADAREAARTALHAVA
EGRDPAGEKQAARVEVAAVQTMRFGAVAADYIERYAKPRNRSWRETESFLTRTLDATDKWQEKDVRAIGRKDVRDALDAV
VARGASIHANRLFAALRRFFAWTVERGILDASPMAGLKPPSPEISRDRVLTDAELVAVWKAAGEVGYPFGPVVQLLILTG
QRRSEVVEAEWREFDLDGATWTIPRERAKNDRAHVVPLAPQAVKILRCIPCVGTRSRLLFTTTGETAFSGVSKATDRLQG
LSAKHLPEGIEVEPWRLHDLRRTFASGCARLGVAVHVVEKALNHVSGTHSGIVGVYQRHSYGDERRCAMELWAAHLDGLV
GGAAKVVKLERRVS

Sequences:

>Translated_414_residues
MAVLTARAVELAKPDPGKRREVPDAALPGLYLVVQPAGGKSWAVRYRAAGKPRKLTLGPYPRLGLADAREAARTALHAVA
EGRDPAGEKQAARVEVAAVQTMRFGAVAADYIERYAKPRNRSWRETESFLTRTLDATDKWQEKDVRAIGRKDVRDALDAV
VARGASIHANRLFAALRRFFAWTVERGILDASPMAGLKPPSPEISRDRVLTDAELVAVWKAAGEVGYPFGPVVQLLILTG
QRRSEVVEAEWREFDLDGATWTIPRERAKNDRAHVVPLAPQAVKILRCIPCVGTRSRLLFTTTGETAFSGVSKATDRLQG
LSAKHLPEGIEVEPWRLHDLRRTFASGCARLGVAVHVVEKALNHVSGTHSGIVGVYQRHSYGDERRCAMELWAAHLDGLV
GGAAKVVKLERRVS
>Mature_413_residues
AVLTARAVELAKPDPGKRREVPDAALPGLYLVVQPAGGKSWAVRYRAAGKPRKLTLGPYPRLGLADAREAARTALHAVAE
GRDPAGEKQAARVEVAAVQTMRFGAVAADYIERYAKPRNRSWRETESFLTRTLDATDKWQEKDVRAIGRKDVRDALDAVV
ARGASIHANRLFAALRRFFAWTVERGILDASPMAGLKPPSPEISRDRVLTDAELVAVWKAAGEVGYPFGPVVQLLILTGQ
RRSEVVEAEWREFDLDGATWTIPRERAKNDRAHVVPLAPQAVKILRCIPCVGTRSRLLFTTTGETAFSGVSKATDRLQGL
SAKHLPEGIEVEPWRLHDLRRTFASGCARLGVAVHVVEKALNHVSGTHSGIVGVYQRHSYGDERRCAMELWAAHLDGLVG
GAAKVVKLERRVS

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=411, Percent_Identity=28.2238442822384, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788974, Length=404, Percent_Identity=25.7425742574257, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788690, Length=431, Percent_Identity=24.3619489559165, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 45410; Mature: 45278

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLTARAVELAKPDPGKRREVPDAALPGLYLVVQPAGGKSWAVRYRAAGKPRKLTLGPY
CCEEEHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCEEEECCC
PRLGLADAREAARTALHAVAEGRDPAGEKQAARVEVAAVQTMRFGAVAADYIERYAKPRN
CCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RSWRETESFLTRTLDATDKWQEKDVRAIGRKDVRDALDAVVARGASIHANRLFAALRRFF
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AWTVERGILDASPMAGLKPPSPEISRDRVLTDAELVAVWKAAGEVGYPFGPVVQLLILTG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
QRRSEVVEAEWREFDLDGATWTIPRERAKNDRAHVVPLAPQAVKILRCIPCVGTRSRLLF
CHHHHHHHHHHHHCCCCCCEEECCHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCCEEEE
TTTGETAFSGVSKATDRLQGLSAKHLPEGIEVEPWRLHDLRRTFASGCARLGVAVHVVEK
EECCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALNHVSGTHSGIVGVYQRHSYGDERRCAMELWAAHLDGLVGGAAKVVKLERRVS
HHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
AVLTARAVELAKPDPGKRREVPDAALPGLYLVVQPAGGKSWAVRYRAAGKPRKLTLGPY
CEEEHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCEEEECCC
PRLGLADAREAARTALHAVAEGRDPAGEKQAARVEVAAVQTMRFGAVAADYIERYAKPRN
CCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RSWRETESFLTRTLDATDKWQEKDVRAIGRKDVRDALDAVVARGASIHANRLFAALRRFF
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AWTVERGILDASPMAGLKPPSPEISRDRVLTDAELVAVWKAAGEVGYPFGPVVQLLILTG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
QRRSEVVEAEWREFDLDGATWTIPRERAKNDRAHVVPLAPQAVKILRCIPCVGTRSRLLF
CHHHHHHHHHHHHCCCCCCEEECCHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCCEEEE
TTTGETAFSGVSKATDRLQGLSAKHLPEGIEVEPWRLHDLRRTFASGCARLGVAVHVVEK
EECCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALNHVSGTHSGIVGVYQRHSYGDERRCAMELWAAHLDGLVGGAAKVVKLERRVS
HHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]