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The map label for this gene is fnrL [H]

Identifier: 218531318

GI number: 218531318

Start: 3571656

End: 3572810

Strand: Reverse

Name: fnrL [H]

Synonym: Mchl_3385

Alternate gene names: 218531318

Gene position: 3572810-3571656 (Counterclockwise)

Preceding gene: 218531321

Following gene: 218531317

Centisome position: 61.84

GC content: 64.85

Gene sequence:

>1155_bases
ATGATGAGCCTCGACCAACAGCCCTCGGTCTTGCTGACGGAAGAGGTTCCGTTGGTGGGCATGGATCTGAGCGACACCTT
GGAGCAGGCGGGCTACCGTGTGCTCGGGCCGGCTGCCACAGCGTCCCAGGCGCTGAGCCTGCTGGAGCAGGAGACGCCGG
CTCTAGCCGTCATCGACATCATGTTGAAGGACGGACCCTGCACCGAGCTGGCGCGCGAGCTGCGTCGACGCGGCGTGGCC
TTCCTCGTCCACTCCGGATGCTACCAGGATGAGCCGCTCGCCAGTGAGTTCCTGGGCGTACCCTGGATCAGCAAGCCGGC
ACCGCCCGACGACGTGGTGTCGGTCCTCGGTGAGCTGTTGCTGACGACTGCATCCACCAGACAGGATGCGGCAGCTGCCA
CGCCCCTCCGGCTCGTCGAGCAGAGCACGGCACGGGGCAATCCGCTCATCCGCAAGCTGGAGAGGTTCGCCATGCTCTCC
GAGGCGGACCGCGCTTTGCTGGAGCAGATCAGCGCAAGCCCACGCACCGTTCCGGCCGGCACAGACCTCGTGCGCGAGGG
CGACGAGCCTGATGGCGTGTTCCTGGTGCTGTCGGGCTTTGCCTGCCGCCACAAGATGCGTGCGAACGGCGCTCGCCAGA
TCAACGCCTACCTCTTGCCGGGCGACCTCTGCGATCTCGACGTGGCGCTCCTGGACGAGATGGACCACACCATCACCACA
CTCTCAGTCTGCAAGGTGGTGCTCCTTGCGCCGGAGGTGATCGCCAACCTTCTGAGCCATCATCCTCAGATCGCTCGTGC
TTTGCGTAAGAGCACGCTTGTGGACGAGGCGACCTTGCGGGAGTGGCTGATAAACATCGGTCGGCGTTCGACCATCGAGC
GGCTAGCCCACCTCTTCTGCGAGGTTCTGCTGCGGCTGCGAGCTGTCGGTCTAGCGGATGAGACCAGCTACGAGCTGCCG
CTGACGCAGGTGGACTTGGCGGACACCACCGGAACCACTTCCATTCACGTCAACCGCTCGCTCAGGGAACTGCGGCAGCG
AGGGCTGATCGAACTTGAAGGTGGCCGGCTGACGATCCTCGACTACGCCCGCCTGCGAGCGCTTGCCGAGTTCAGGGCCA
ACTACCTGCACCTGAGAGATCGAGCCGCCGCATGA

Upstream 100 bases:

>100_bases
GCCAAGGCCCTCTCCCGGTTCGCCCAAGCTATGTCTATTGCTTTGGTTATGGAGCCTCGCTTCGGCGGGAAGACGAGCGG
CTCAAGCAGCCGGAGTTTGC

Downstream 100 bases:

>100_bases
ACCTGCGCCTTCAGCCCGTTCAGGTCGCCACGGGTAGCGACGACGGGGAGAGCCGGCTCGTCTTTCACGAGAGCTTCCTT
GTGGCGGTGCTGGTGTAGCT

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MMSLDQQPSVLLTEEVPLVGMDLSDTLEQAGYRVLGPAATASQALSLLEQETPALAVIDIMLKDGPCTELARELRRRGVA
FLVHSGCYQDEPLASEFLGVPWISKPAPPDDVVSVLGELLLTTASTRQDAAAATPLRLVEQSTARGNPLIRKLERFAMLS
EADRALLEQISASPRTVPAGTDLVREGDEPDGVFLVLSGFACRHKMRANGARQINAYLLPGDLCDLDVALLDEMDHTITT
LSVCKVVLLAPEVIANLLSHHPQIARALRKSTLVDEATLREWLINIGRRSTIERLAHLFCEVLLRLRAVGLADETSYELP
LTQVDLADTTGTTSIHVNRSLRELRQRGLIELEGGRLTILDYARLRALAEFRANYLHLRDRAAA

Sequences:

>Translated_384_residues
MMSLDQQPSVLLTEEVPLVGMDLSDTLEQAGYRVLGPAATASQALSLLEQETPALAVIDIMLKDGPCTELARELRRRGVA
FLVHSGCYQDEPLASEFLGVPWISKPAPPDDVVSVLGELLLTTASTRQDAAAATPLRLVEQSTARGNPLIRKLERFAMLS
EADRALLEQISASPRTVPAGTDLVREGDEPDGVFLVLSGFACRHKMRANGARQINAYLLPGDLCDLDVALLDEMDHTITT
LSVCKVVLLAPEVIANLLSHHPQIARALRKSTLVDEATLREWLINIGRRSTIERLAHLFCEVLLRLRAVGLADETSYELP
LTQVDLADTTGTTSIHVNRSLRELRQRGLIELEGGRLTILDYARLRALAEFRANYLHLRDRAAA
>Mature_384_residues
MMSLDQQPSVLLTEEVPLVGMDLSDTLEQAGYRVLGPAATASQALSLLEQETPALAVIDIMLKDGPCTELARELRRRGVA
FLVHSGCYQDEPLASEFLGVPWISKPAPPDDVVSVLGELLLTTASTRQDAAAATPLRLVEQSTARGNPLIRKLERFAMLS
EADRALLEQISASPRTVPAGTDLVREGDEPDGVFLVLSGFACRHKMRANGARQINAYLLPGDLCDLDVALLDEMDHTITT
LSVCKVVLLAPEVIANLLSHHPQIARALRKSTLVDEATLREWLINIGRRSTIERLAHLFCEVLLRLRAVGLADETSYELP
LTQVDLADTTGTTSIHVNRSLRELRQRGLIELEGGRLTILDYARLRALAEFRANYLHLRDRAAA

Specific function: Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 42129; Mature: 42129

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50042 CNMP_BINDING_3 ; PS50110 RESPONSE_REGULATORY ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSLDQQPSVLLTEEVPLVGMDLSDTLEQAGYRVLGPAATASQALSLLEQETPALAVIDI
CCCCCCCCCEEEECCCCEECCCHHHHHHHCCCEEECCHHHHHHHHHHHHHCCCCEEEEEE
MLKDGPCTELARELRRRGVAFLVHSGCYQDEPLASEFLGVPWISKPAPPDDVVSVLGELL
EECCCCHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHH
LTTASTRQDAAAATPLRLVEQSTARGNPLIRKLERFAMLSEADRALLEQISASPRTVPAG
HHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TDLVREGDEPDGVFLVLSGFACRHKMRANGARQINAYLLPGDLCDLDVALLDEMDHTITT
CHHHHCCCCCCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
LSVCKVVLLAPEVIANLLSHHPQIARALRKSTLVDEATLREWLINIGRRSTIERLAHLFC
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EVLLRLRAVGLADETSYELPLTQVDLADTTGTTSIHVNRSLRELRQRGLIELEGGRLTIL
HHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEEECHHHHHHHHCCCEEECCCEEEEH
DYARLRALAEFRANYLHLRDRAAA
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMSLDQQPSVLLTEEVPLVGMDLSDTLEQAGYRVLGPAATASQALSLLEQETPALAVIDI
CCCCCCCCCEEEECCCCEECCCHHHHHHHCCCEEECCHHHHHHHHHHHHHCCCCEEEEEE
MLKDGPCTELARELRRRGVAFLVHSGCYQDEPLASEFLGVPWISKPAPPDDVVSVLGELL
EECCCCHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHH
LTTASTRQDAAAATPLRLVEQSTARGNPLIRKLERFAMLSEADRALLEQISASPRTVPAG
HHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TDLVREGDEPDGVFLVLSGFACRHKMRANGARQINAYLLPGDLCDLDVALLDEMDHTITT
CHHHHCCCCCCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
LSVCKVVLLAPEVIANLLSHHPQIARALRKSTLVDEATLREWLINIGRRSTIERLAHLFC
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EVLLRLRAVGLADETSYELPLTQVDLADTTGTTSIHVNRSLRELRQRGLIELEGGRLTIL
HHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEEECHHHHHHHHCCCEEECCCEEEEH
DYARLRALAEFRANYLHLRDRAAA
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592416 [H]