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The map label for this gene is gpo [H]

Identifier: 218531226

GI number: 218531226

Start: 3454013

End: 3454507

Strand: Reverse

Name: gpo [H]

Synonym: Mchl_3277

Alternate gene names: 218531226

Gene position: 3454507-3454013 (Counterclockwise)

Preceding gene: 218531230

Following gene: 218531221

Centisome position: 59.79

GC content: 66.46

Gene sequence:

>495_bases
ATGAGCAACCTCTACGATCACGCTCCGCGCGACGCGCGCGGCGGACCGCATCCCCTGTCGCAGTATCGCGGCAAGGTGCT
TCTGGTGGTCAACACCGCCTCGAAATGCGGGTTCACGCCGCAATATCAGGGCTTGGAGACCCTATGGCGGCGCCATCGTG
CCCGCGGCCTCGTGGTGCTCGGCCTGCCCTGCAACCAGTTCGGAGCACAGGAGCCGGGCGATGCCGCCGCCATCGAACAG
TTCTGCTCGCTGACCTACGACGTGACCTTTCCGGTCCTCGCCAAGGTGGAGGTCAACGGCCCGGGCGCCGACCCGTTCTA
TGTCGATCTCAAGCGCGAGAAGCCCGGCCTGTTCGGCACGCAGGCCATCAAGTGGAATTTCACGAAATTCCTGATCGGCC
GGGACGGCCGGGTGATCGGCCGCTTCTCCCCATCCACAAAGCCCGAGGCCCTGGACGGTGCGATCGAGCGGGCCCTGGCC
GAGCCGGGCGAGTAG

Upstream 100 bases:

>100_bases
ATGGAATTTCCAGTCGAGCCTGGAATCGTTCCACGAAATTCAGGACAATATCACCCTTGGAGGCGGGACTATTGAGCAAT
CGACGGCGTTGGGAGCGGTC

Downstream 100 bases:

>100_bases
CCCTTACCGTCCCACCCGTGACGTCGGCCCCGGATCGATCGCCGGCAACTCGCCGGGGGGCAGGCCGGGGATCGCGGCGG
ATGCCTGCGGCGCTTCGAGG

Product: peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MSNLYDHAPRDARGGPHPLSQYRGKVLLVVNTASKCGFTPQYQGLETLWRRHRARGLVVLGLPCNQFGAQEPGDAAAIEQ
FCSLTYDVTFPVLAKVEVNGPGADPFYVDLKREKPGLFGTQAIKWNFTKFLIGRDGRVIGRFSPSTKPEALDGAIERALA
EPGE

Sequences:

>Translated_164_residues
MSNLYDHAPRDARGGPHPLSQYRGKVLLVVNTASKCGFTPQYQGLETLWRRHRARGLVVLGLPCNQFGAQEPGDAAAIEQ
FCSLTYDVTFPVLAKVEVNGPGADPFYVDLKREKPGLFGTQAIKWNFTKFLIGRDGRVIGRFSPSTKPEALDGAIERALA
EPGE
>Mature_163_residues
SNLYDHAPRDARGGPHPLSQYRGKVLLVVNTASKCGFTPQYQGLETLWRRHRARGLVVLGLPCNQFGAQEPGDAAAIEQF
CSLTYDVTFPVLAKVEVNGPGADPFYVDLKREKPGLFGTQAIKWNFTKFLIGRDGRVIGRFSPSTKPEALDGAIERALAE
PGE

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=150, Percent_Identity=40.6666666666667, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI75709200, Length=153, Percent_Identity=38.562091503268, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI90903240, Length=153, Percent_Identity=38.562091503268, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI192455698, Length=155, Percent_Identity=34.8387096774194, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=39.6946564885496, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI6006001, Length=150, Percent_Identity=40, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI4557629, Length=144, Percent_Identity=38.1944444444444, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI41406084, Length=186, Percent_Identity=35.4838709677419, Blast_Score=84, Evalue=4e-17,
Organism=Homo sapiens, GI33186887, Length=155, Percent_Identity=32.258064516129, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=30.3867403314917, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1788003, Length=173, Percent_Identity=43.3526011560694, Blast_Score=139, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17506887, Length=162, Percent_Identity=44.4444444444444, Blast_Score=142, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=45.625, Blast_Score=141, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI193210707, Length=164, Percent_Identity=42.0731707317073, Blast_Score=123, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71993584, Length=157, Percent_Identity=36.3057324840764, Blast_Score=107, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17550320, Length=186, Percent_Identity=32.258064516129, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193209493, Length=187, Percent_Identity=30.4812834224599, Blast_Score=90, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71999642, Length=72, Percent_Identity=40.2777777777778, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322228, Length=161, Percent_Identity=52.1739130434783, Blast_Score=190, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6319721, Length=160, Percent_Identity=50, Blast_Score=186, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322826, Length=164, Percent_Identity=45.1219512195122, Blast_Score=159, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24656767, Length=162, Percent_Identity=43.2098765432099, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24656777, Length=162, Percent_Identity=43.2098765432099, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24656772, Length=162, Percent_Identity=43.2098765432099, Blast_Score=126, Evalue=7e-30,
Organism=Drosophila melanogaster, GI85726443, Length=152, Percent_Identity=39.4736842105263, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17987; Mature: 17855

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLYDHAPRDARGGPHPLSQYRGKVLLVVNTASKCGFTPQYQGLETLWRRHRARGLVVL
CCCCCCCCCCCCCCCCCCHHHHCCEEEEEEECCHHCCCCCCCCCHHHHHHHHHHCCEEEE
GLPCNQFGAQEPGDAAAIEQFCSLTYDVTFPVLAKVEVNGPGADPFYVDLKREKPGLFGT
CCCCHHHCCCCCCCHHHHHHHHCCEEEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCC
QAIKWNFTKFLIGRDGRVIGRFSPSTKPEALDGAIERALAEPGE
EEEEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SNLYDHAPRDARGGPHPLSQYRGKVLLVVNTASKCGFTPQYQGLETLWRRHRARGLVVL
CCCCCCCCCCCCCCCCCHHHHCCEEEEEEECCHHCCCCCCCCCHHHHHHHHHHCCEEEE
GLPCNQFGAQEPGDAAAIEQFCSLTYDVTFPVLAKVEVNGPGADPFYVDLKREKPGLFGT
CCCCHHHCCCCCCCHHHHHHHHCCEEEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCC
QAIKWNFTKFLIGRDGRVIGRFSPSTKPEALDGAIERALAEPGE
EEEEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]