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The map label for this gene is ureC [H]

Identifier: 218531191

GI number: 218531191

Start: 3423469

End: 3425196

Strand: Reverse

Name: ureC [H]

Synonym: Mchl_3242

Alternate gene names: 218531191

Gene position: 3425196-3423469 (Counterclockwise)

Preceding gene: 218531192

Following gene: 218531190

Centisome position: 59.28

GC content: 67.3

Gene sequence:

>1728_bases
ATGGCCGACATCCGCAAGCCCGCCGCCCTCCCCCGCGCCGCCTACGCCGCCATGTTCGGGCCGACCACCGGGGACCGTAT
CCGGCTGGCCGACACCAGCCTCGAGATCGAGATCGAGCGTGATCTCACGACCTACGGCGAGGAGGTGAAGTTCGGCGGCG
GCAAGGTGATCCGCGACGGGATGGGCCAATCGCAGGCGACCAACGCCGCAGGCGCCGTCGATACCGTCATCACCAACGCG
GTGGTGCTCGACCATTGGGGCATCGTGAAATGCGATGTCGGCATCCGCGCCGGCCGTATCTTCAAGCTCGGAAAGGCCGG
CAACCCGGACGTTCAGGCGAATGTCGACATCGTCGTCGGCCCCGGCACCGAGGTGATCGCGGGCGAGGGCAAGATCCTCA
CGGCCGGCGGCTTCGACAGCCATATCCACTTCATCTGCCCGCAGCAGATCGAGGAAGCGCTCTGCTCCGGTGTGACGACG
ATGCTCGGCGGCGGCACCGGGCCGGCGCACGGCACCTTCGCCACCACCTGCACCCCCGGCCCCTGGCACATCGCCCGGAT
GATCGAGGCGGCCGATTCCTTCCCGATGAACCTCGCCTTTGCCGGCAAGGGCAATGCCTCGGTGCCCGGCGCGCTGGAGG
AGATGATCCGCGCTGGCGCCTGCGCGATGAAGTTGCATGAGGATTGGGGCACGACGCCCGCCGCGATCGATACCTGCCTC
TCGGTGGCGGATGCCTTCGATGTGCAGGTCATGATCCACACCGACACGCTCAACGAATCGGGCTTCGTCGAGGACACCAT
CGCCGCCTTCAAGGGCCGCACCATCCACGCCTTCCACACCGAGGGCGCCGGCGGCGGTCACGCGCCGGACATCATGCGCG
TGGCGGGGTTGGCCAACGTGCTCCCGTCGTCCACGAACCCGACGCGCCCATACACAAAAAATACCATCGACGAGCATCTC
GACATGCTGATGGTGTGCCACCACCTCGACCCGTCGATTCCCGAAGACCTCGCCTTCGCCGAGAGCCGCATCCGCAAGGA
AACCATCGCGGCCGAGGACATCCTGCACGACATCGGTGCCCTCTCGATGATGTCGTCCGACAGTCAGGCGATGGGCCGTG
TCGGCGAAGTCGTGATCCGCACCTGGCAGACCGCCGACAAGATGAAGCGCCAGCGCGGCGCCTTGCCCGGAGACGCGTCG
GGCAACGACAACCTGCGCGCCCGGCGCTACGTGGCGAAATACACGATCAACCCGGCCATCGCGCACGGCGTCTCGCGCCA
TATCGGCTCGATCGAGCCGGGCAAGCTCGCCGACCTCGTGCTGTGGACGCCCGCCTTCTTCGGCGTGAAGCCGGACCTCG
TGCTCAAGGGGGGCATGATCGCCACCGCGCCGATGGGCGACCCCAACGCCTCGATCCCGACGCCGCAGCCGGTGCATTAC
CGGCCGATGTTCGGCGCCTATGGCCGCGCGCCCTATGCCACCGCGCTCACCTTCGTCTCGCGGGCGGCGCTCGAGGACGG
CGTGAAGGAGAAGCTGCGCGTCTCCAAGGAGCTGGTGGCGGTGGAGAACGTGCGCGGCGGCATCTCGAAGAAGAGCATGA
TCCTCAACGACGCGACCCCGAACATCGAGATCGACCCCGAGACCTACGACGTGCGCGCCGACGGCGAATTGCTGGTCTGC
GAGCCGGCGGAGGTCTTGCCGATGGCGCAGCGCTACTTCCTGTTCTGA

Upstream 100 bases:

>100_bases
CCTGGGCGGAAGAAGTCGTGGCGGGCTGCCGCGGCACCAATGCCCCCCTGGAAGATCGCTTCGACCGCGCGGTCGCCGAG
GCGCGAGGGACTCTTTAGAC

Downstream 100 bases:

>100_bases
GCTATGGTCGGCCTGTCACAGGAGGTCTCTTAATGACCAGGGCTGCGCTGAAGCCGCCTCCGGCGGCCGATCTCTATGAC
AGGGATTTTTACGCCTGGAC

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MADIRKPAALPRAAYAAMFGPTTGDRIRLADTSLEIEIERDLTTYGEEVKFGGGKVIRDGMGQSQATNAAGAVDTVITNA
VVLDHWGIVKCDVGIRAGRIFKLGKAGNPDVQANVDIVVGPGTEVIAGEGKILTAGGFDSHIHFICPQQIEEALCSGVTT
MLGGGTGPAHGTFATTCTPGPWHIARMIEAADSFPMNLAFAGKGNASVPGALEEMIRAGACAMKLHEDWGTTPAAIDTCL
SVADAFDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIMRVAGLANVLPSSTNPTRPYTKNTIDEHL
DMLMVCHHLDPSIPEDLAFAESRIRKETIAAEDILHDIGALSMMSSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGDAS
GNDNLRARRYVAKYTINPAIAHGVSRHIGSIEPGKLADLVLWTPAFFGVKPDLVLKGGMIATAPMGDPNASIPTPQPVHY
RPMFGAYGRAPYATALTFVSRAALEDGVKEKLRVSKELVAVENVRGGISKKSMILNDATPNIEIDPETYDVRADGELLVC
EPAEVLPMAQRYFLF

Sequences:

>Translated_575_residues
MADIRKPAALPRAAYAAMFGPTTGDRIRLADTSLEIEIERDLTTYGEEVKFGGGKVIRDGMGQSQATNAAGAVDTVITNA
VVLDHWGIVKCDVGIRAGRIFKLGKAGNPDVQANVDIVVGPGTEVIAGEGKILTAGGFDSHIHFICPQQIEEALCSGVTT
MLGGGTGPAHGTFATTCTPGPWHIARMIEAADSFPMNLAFAGKGNASVPGALEEMIRAGACAMKLHEDWGTTPAAIDTCL
SVADAFDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIMRVAGLANVLPSSTNPTRPYTKNTIDEHL
DMLMVCHHLDPSIPEDLAFAESRIRKETIAAEDILHDIGALSMMSSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGDAS
GNDNLRARRYVAKYTINPAIAHGVSRHIGSIEPGKLADLVLWTPAFFGVKPDLVLKGGMIATAPMGDPNASIPTPQPVHY
RPMFGAYGRAPYATALTFVSRAALEDGVKEKLRVSKELVAVENVRGGISKKSMILNDATPNIEIDPETYDVRADGELLVC
EPAEVLPMAQRYFLF
>Mature_574_residues
ADIRKPAALPRAAYAAMFGPTTGDRIRLADTSLEIEIERDLTTYGEEVKFGGGKVIRDGMGQSQATNAAGAVDTVITNAV
VLDHWGIVKCDVGIRAGRIFKLGKAGNPDVQANVDIVVGPGTEVIAGEGKILTAGGFDSHIHFICPQQIEEALCSGVTTM
LGGGTGPAHGTFATTCTPGPWHIARMIEAADSFPMNLAFAGKGNASVPGALEEMIRAGACAMKLHEDWGTTPAAIDTCLS
VADAFDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIMRVAGLANVLPSSTNPTRPYTKNTIDEHLD
MLMVCHHLDPSIPEDLAFAESRIRKETIAAEDILHDIGALSMMSSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGDASG
NDNLRARRYVAKYTINPAIAHGVSRHIGSIEPGKLADLVLWTPAFFGVKPDLVLKGGMIATAPMGDPNASIPTPQPVHYR
PMFGAYGRAPYATALTFVSRAALEDGVKEKLRVSKELVAVENVRGGISKKSMILNDATPNIEIDPETYDVRADGELLVCE
PAEVLPMAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 61246; Mature: 61114

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIRKPAALPRAAYAAMFGPTTGDRIRLADTSLEIEIERDLTTYGEEVKFGGGKVIRDG
CCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCEEEEEEECCHHHCCCEEECCCCEEEECC
MGQSQATNAAGAVDTVITNAVVLDHWGIVKCDVGIRAGRIFKLGKAGNPDVQANVDIVVG
CCCCCCCCCCCHHHHHHHCEEEEECCCEEEECCCCCCCCEEEECCCCCCCCEEEEEEEEC
PGTEVIAGEGKILTAGGFDSHIHFICPQQIEEALCSGVTTMLGGGTGPAHGTFATTCTPG
CCCEEEECCCEEEEECCCCCCEEEECHHHHHHHHHCCHHHHHCCCCCCCCCCEEEECCCC
PWHIARMIEAADSFPMNLAFAGKGNASVPGALEEMIRAGACAMKLHEDWGTTPAAIDTCL
HHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCHHHEEEHHHCCCCHHHHHHHH
SVADAFDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIMRVAGLANV
HHHCCCEEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
LPSSTNPTRPYTKNTIDEHLDMLMVCHHLDPSIPEDLAFAESRIRKETIAAEDILHDIGA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LSMMSSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGDASGNDNLRARRYVAKYTINPAI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEEECCHHH
AHGVSRHIGSIEPGKLADLVLWTPAFFGVKPDLVLKGGMIATAPMGDPNASIPTPQPVHY
HHHHHHHCCCCCCCCHHEEEEECHHHHCCCCCEEEECCEEEECCCCCCCCCCCCCCCCEE
RPMFGAYGRAPYATALTFVSRAALEDGVKEKLRVSKELVAVENVRGGISKKSMILNDATP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
NIEIDPETYDVRADGELLVCEPAEVLPMAQRYFLF
CEEECCCEEEEECCCCEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
ADIRKPAALPRAAYAAMFGPTTGDRIRLADTSLEIEIERDLTTYGEEVKFGGGKVIRDG
CCCCCCCCCCHHHHHHHCCCCCCCEEEEECCEEEEEEECCHHHCCCEEECCCCEEEECC
MGQSQATNAAGAVDTVITNAVVLDHWGIVKCDVGIRAGRIFKLGKAGNPDVQANVDIVVG
CCCCCCCCCCCHHHHHHHCEEEEECCCEEEECCCCCCCCEEEECCCCCCCCEEEEEEEEC
PGTEVIAGEGKILTAGGFDSHIHFICPQQIEEALCSGVTTMLGGGTGPAHGTFATTCTPG
CCCEEEECCCEEEEECCCCCCEEEECHHHHHHHHHCCHHHHHCCCCCCCCCCEEEECCCC
PWHIARMIEAADSFPMNLAFAGKGNASVPGALEEMIRAGACAMKLHEDWGTTPAAIDTCL
HHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCHHHEEEHHHCCCCHHHHHHHH
SVADAFDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIMRVAGLANV
HHHCCCEEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
LPSSTNPTRPYTKNTIDEHLDMLMVCHHLDPSIPEDLAFAESRIRKETIAAEDILHDIGA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LSMMSSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGDASGNDNLRARRYVAKYTINPAI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEEECCHHH
AHGVSRHIGSIEPGKLADLVLWTPAFFGVKPDLVLKGGMIATAPMGDPNASIPTPQPVHY
HHHHHHHCCCCCCCCHHEEEEECHHHHCCCCCEEEECCEEEECCCCCCCCCCCCCCCCEE
RPMFGAYGRAPYATALTFVSRAALEDGVKEKLRVSKELVAVENVRGGISKKSMILNDATP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
NIEIDPETYDVRADGELLVCEPAEVLPMAQRYFLF
CEEECCCEEEEECCCCEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA