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The map label for this gene is rsmB [H]

Identifier: 218531110

GI number: 218531110

Start: 3337387

End: 3338736

Strand: Reverse

Name: rsmB [H]

Synonym: Mchl_3160

Alternate gene names: 218531110

Gene position: 3338736-3337387 (Counterclockwise)

Preceding gene: 218531112

Following gene: 218531109

Centisome position: 57.78

GC content: 72.0

Gene sequence:

>1350_bases
TTGCGGGTCCAAGCGTGGCCGCAAGACGGCAAGTTTAACGAAACGTTTCCGGAGCCGATCCTGACCCCCTCCGCCCGCCT
CTCCGCCGCCATCGAGATCCTCGACGACATCGCCGAGCGCCGCCGTCCGGCCGCCGACGCCCTCAAGGATTGGGGGCTCG
CCCACCGCTACGCCGGCTCCGGTGACCGCGCCGCGATCGCCAGCCTCGTCTATGACGGACTGCGGCGCCGGGCCTCCGCT
GCCTGGGTGATGGGCGCGCAGACCGGCCGAGCCATCGTGATCGGCATGCTGCGCCTTCAGCGCGGTTTGGCCGAGCCCAG
CATCGCCTCGCTGTTCGACGGCGCGCGCTTCGCACCCCCTCCCCTCACCGAGGACGAGCGTAAGCGGCTGGCGGAGGGAA
GCCTCGCCGATGCGCCGCCCGAGGTCGCAGGCGATGCGCCGGCCTTCGTGCTGCCGTCGCTGACCGCTTTGCTCGGCGAT
GCCCTGCTGCCCGAATTGCGGGCGCTCGGCCGCCGGGCGCCGCTCGATATCCGCGTCAACACTCTGAAACAGAGCCGCGA
AGAGGCGTTCGCGGCTTTGGCCGACCTCTCGCCCGAGACGACGCCGCTCTCGGCCCTCGGCCTGCGCATCCCGCTCGGCG
AGGATGGGCGCGGCCCGGCGCTCCATGTCGATCCGCTGTTTCTGGAGGGCGGGTTCGAGATTCAGGACGAGGGTTCGCAG
ATCGCGAGCTTGCTCGCCGGGGCGAAACCGGGCGAGACCGTGGTCGATCTCTGCGCGGGCGGGGGCGGCAAGTCGCTGGC
GCTAGCCGCGATCACCGGCAACGCCGCCCACATCATCGCCACCGATGCCGATCCGCGCCGGCTCGCCCCGATCCATGAGC
GCCTGCGCCGCTCGGGTGCGCAGGTCGAGGTGCGCACGCCGCGCACCGGCAAGGCGCGCGCCGACGTGCTGGCCGATCTC
GACGGCACCGTCGATCGGGTTCTGGTCGATGCGCCCTGCACCGGCACCGGCACCTGGCGCCGCAACCCTGACGCCAAGTG
GCGCCTGCGGCCGGGCAGCCTCGCCGGCCGGCTCGCCGAGCAGGCCGAGGTGCTCGACCGAGCGGCCCGTCTGCTGCGCC
CCGGTGGAACCCTCGTCTACGTCACGTGCTCGCTGCTGCCCGAGGAGAACGACGCCGCCGTCGAGGGATTGCTCCAGCGC
AGCGGGGCGATCCGGCCCGTGGCGACCGATCTCGCGCCCGTGCCCGGTCTCGACGAGAAGGTCCGCAAGACGGCCCGCGG
CATCCAGATGAGCCCGGCGCTCACCGGTACCGACGGTTTCTATGTCGCGACACTGACACGCAAAAGCTGA

Upstream 100 bases:

>100_bases
GGCATCGCAAGGGTCCTTTCCTCACTTGTCCTTGACGGACAGGGCCATCGTGCCGTTCTGAACGTCCAAAGTGCCGGAAG
CTCGGCCTTATCGTGTCGGG

Downstream 100 bases:

>100_bases
TCCGAGGCCGGATCGGTTGCGCGCTTGTCCCGTTGTTCACCGGGACCGCGCGGGGGACAGGCCGGGGCAGCCGCCACGGA
CGAGATTCCTGCGCATTGCC

Product: Fmu (Sun) domain protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MRVQAWPQDGKFNETFPEPILTPSARLSAAIEILDDIAERRRPAADALKDWGLAHRYAGSGDRAAIASLVYDGLRRRASA
AWVMGAQTGRAIVIGMLRLQRGLAEPSIASLFDGARFAPPPLTEDERKRLAEGSLADAPPEVAGDAPAFVLPSLTALLGD
ALLPELRALGRRAPLDIRVNTLKQSREEAFAALADLSPETTPLSALGLRIPLGEDGRGPALHVDPLFLEGGFEIQDEGSQ
IASLLAGAKPGETVVDLCAGGGGKSLALAAITGNAAHIIATDADPRRLAPIHERLRRSGAQVEVRTPRTGKARADVLADL
DGTVDRVLVDAPCTGTGTWRRNPDAKWRLRPGSLAGRLAEQAEVLDRAARLLRPGGTLVYVTCSLLPEENDAAVEGLLQR
SGAIRPVATDLAPVPGLDEKVRKTARGIQMSPALTGTDGFYVATLTRKS

Sequences:

>Translated_449_residues
MRVQAWPQDGKFNETFPEPILTPSARLSAAIEILDDIAERRRPAADALKDWGLAHRYAGSGDRAAIASLVYDGLRRRASA
AWVMGAQTGRAIVIGMLRLQRGLAEPSIASLFDGARFAPPPLTEDERKRLAEGSLADAPPEVAGDAPAFVLPSLTALLGD
ALLPELRALGRRAPLDIRVNTLKQSREEAFAALADLSPETTPLSALGLRIPLGEDGRGPALHVDPLFLEGGFEIQDEGSQ
IASLLAGAKPGETVVDLCAGGGGKSLALAAITGNAAHIIATDADPRRLAPIHERLRRSGAQVEVRTPRTGKARADVLADL
DGTVDRVLVDAPCTGTGTWRRNPDAKWRLRPGSLAGRLAEQAEVLDRAARLLRPGGTLVYVTCSLLPEENDAAVEGLLQR
SGAIRPVATDLAPVPGLDEKVRKTARGIQMSPALTGTDGFYVATLTRKS
>Mature_449_residues
MRVQAWPQDGKFNETFPEPILTPSARLSAAIEILDDIAERRRPAADALKDWGLAHRYAGSGDRAAIASLVYDGLRRRASA
AWVMGAQTGRAIVIGMLRLQRGLAEPSIASLFDGARFAPPPLTEDERKRLAEGSLADAPPEVAGDAPAFVLPSLTALLGD
ALLPELRALGRRAPLDIRVNTLKQSREEAFAALADLSPETTPLSALGLRIPLGEDGRGPALHVDPLFLEGGFEIQDEGSQ
IASLLAGAKPGETVVDLCAGGGGKSLALAAITGNAAHIIATDADPRRLAPIHERLRRSGAQVEVRTPRTGKARADVLADL
DGTVDRVLVDAPCTGTGTWRRNPDAKWRLRPGSLAGRLAEQAEVLDRAARLLRPGGTLVYVTCSLLPEENDAAVEGLLQR
SGAIRPVATDLAPVPGLDEKVRKTARGIQMSPALTGTDGFYVATLTRKS

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=299, Percent_Identity=29.0969899665552, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI76150623, Length=299, Percent_Identity=29.0969899665552, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI32698918, Length=231, Percent_Identity=27.7056277056277, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI23199998, Length=240, Percent_Identity=32.9166666666667, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI8922322, Length=240, Percent_Identity=32.9166666666667, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI270288818, Length=240, Percent_Identity=32.9166666666667, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI270288816, Length=240, Percent_Identity=32.9166666666667, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI39995082, Length=203, Percent_Identity=30.0492610837438, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI301336155, Length=203, Percent_Identity=30.0492610837438, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI40316918, Length=199, Percent_Identity=32.1608040201005, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI11545785, Length=165, Percent_Identity=30.9090909090909, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI2367212, Length=422, Percent_Identity=27.7251184834123, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87081985, Length=285, Percent_Identity=31.2280701754386, Blast_Score=108, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17536757, Length=316, Percent_Identity=29.4303797468354, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25143471, Length=190, Percent_Identity=34.2105263157895, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71998419, Length=305, Percent_Identity=26.5573770491803, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534021, Length=225, Percent_Identity=28, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319447, Length=208, Percent_Identity=33.6538461538462, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324268, Length=291, Percent_Identity=25.085910652921, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI22024126, Length=325, Percent_Identity=29.2307692307692, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19920494, Length=235, Percent_Identity=31.4893617021277, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355201, Length=208, Percent_Identity=29.8076923076923, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24668781, Length=233, Percent_Identity=24.4635193133047, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356513, Length=233, Percent_Identity=24.4635193133047, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 47551; Mature: 47551

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVQAWPQDGKFNETFPEPILTPSARLSAAIEILDDIAERRRPAADALKDWGLAHRYAGS
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCC
GDRAAIASLVYDGLRRRASAAWVMGAQTGRAIVIGMLRLQRGLAEPSIASLFDGARFAPP
CCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCC
PLTEDERKRLAEGSLADAPPEVAGDAPAFVLPSLTALLGDALLPELRALGRRAPLDIRVN
CCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHH
TLKQSREEAFAALADLSPETTPLSALGLRIPLGEDGRGPALHVDPLFLEGGFEIQDEGSQ
HHHHHHHHHHHHHHHCCCCCCCHHHHEEEEECCCCCCCCEEEECCEEECCCCEECCCHHH
IASLLAGAKPGETVVDLCAGGGGKSLALAAITGNAAHIIATDADPRRLAPIHERLRRSGA
HHHHHHCCCCCHHHHHHHCCCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCC
QVEVRTPRTGKARADVLADLDGTVDRVLVDAPCTGTGTWRRNPDAKWRLRPGSLAGRLAE
EEEEECCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHHH
QAEVLDRAARLLRPGGTLVYVTCSLLPEENDAAVEGLLQRSGAIRPVATDLAPVPGLDEK
HHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHCCCCCCCCHHH
VRKTARGIQMSPALTGTDGFYVATLTRKS
HHHHHCCCEECCCEECCCCEEEEEEECCC
>Mature Secondary Structure
MRVQAWPQDGKFNETFPEPILTPSARLSAAIEILDDIAERRRPAADALKDWGLAHRYAGS
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCC
GDRAAIASLVYDGLRRRASAAWVMGAQTGRAIVIGMLRLQRGLAEPSIASLFDGARFAPP
CCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCC
PLTEDERKRLAEGSLADAPPEVAGDAPAFVLPSLTALLGDALLPELRALGRRAPLDIRVN
CCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHH
TLKQSREEAFAALADLSPETTPLSALGLRIPLGEDGRGPALHVDPLFLEGGFEIQDEGSQ
HHHHHHHHHHHHHHHCCCCCCCHHHHEEEEECCCCCCCCEEEECCEEECCCCEECCCHHH
IASLLAGAKPGETVVDLCAGGGGKSLALAAITGNAAHIIATDADPRRLAPIHERLRRSGA
HHHHHHCCCCCHHHHHHHCCCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCC
QVEVRTPRTGKARADVLADLDGTVDRVLVDAPCTGTGTWRRNPDAKWRLRPGSLAGRLAE
EEEEECCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHHH
QAEVLDRAARLLRPGGTLVYVTCSLLPEENDAAVEGLLQRSGAIRPVATDLAPVPGLDEK
HHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHCCCCCCCCHHH
VRKTARGIQMSPALTGTDGFYVATLTRKS
HHHHHCCCEECCCEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]