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The map label for this gene is pgsA [H]

Identifier: 218531053

GI number: 218531053

Start: 3283164

End: 3283763

Strand: Reverse

Name: pgsA [H]

Synonym: Mchl_3103

Alternate gene names: 218531053

Gene position: 3283763-3283164 (Counterclockwise)

Preceding gene: 218531054

Following gene: 218531052

Centisome position: 56.83

GC content: 70.5

Gene sequence:

>600_bases
ATGAACGCCGTCCTCCCCCGACGCCGGTCGCAGGCCTGGACGCTCGCGAACTGCCTCACCTACGGCCGCCTCGTCGCGGT
GCCGGTCGTCGTCGTCCTGCTGTTCTGGCCGGACGAGTTCGCCGCGCGCTGGACCGCCTTCGGCGTGTTCGTGGCCGCCG
CGATCACCGACTATCTCGACGGCTACGTCGCCCGCGCCTGGGCGCAGAGTTCGGCGCTCGGGCGGATGCTCGATCCGATC
GCCGACAAGCTCCTCGTCGCCGCCCTCCTCCTGATGCTAGCCGCGGACCGCACCATCGCCGGCATGTCGCTCTGGGCGGC
GATCGTCATCCTGTGCCGCGAGGTGCTGGTTTCCGGCCTGCGCGAGTATCTGGCGGAACTGAAGGTCGGTCTGCCGGTCA
GCCGGATCGCGAAGTGGAAGACGACGGTCCAGCTCATCGCCCTCGGCTTCCTCGTCGCCGGCCCGGCCGGCGAAGCCGTC
CTTCCCGGCAGCCTCACCGCCGGCATCGTCCTGCTCTGGCTCGCCGCGGCCCTCACGCTCTACACCGGCTGGGACTACAT
GAGGGCCGGGATCCGGCACGTGATCGACGATCCGCGCTGA

Upstream 100 bases:

>100_bases
CATGCCAATGCTTGAGCCGAGCCCCGTGCCGAGAGAGCCCGCACCCGATGCAGCGACGCCGCGGTTGACGCCCCCCGCCG
CCCGTGATTTCACCCCGGCG

Downstream 100 bases:

>100_bases
TTGGTTTGGGATTCTTTGGCGCGGCACTGCGAGGCGCCGCCGGGGATGAATGCGATGAAGCTCGTCTACTTCGCCTGGGT
GCGCGAGCGCGTCGGCAAGC

Product: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MNAVLPRRRSQAWTLANCLTYGRLVAVPVVVVLLFWPDEFAARWTAFGVFVAAAITDYLDGYVARAWAQSSALGRMLDPI
ADKLLVAALLLMLAADRTIAGMSLWAAIVILCREVLVSGLREYLAELKVGLPVSRIAKWKTTVQLIALGFLVAGPAGEAV
LPGSLTAGIVLLWLAAALTLYTGWDYMRAGIRHVIDDPR

Sequences:

>Translated_199_residues
MNAVLPRRRSQAWTLANCLTYGRLVAVPVVVVLLFWPDEFAARWTAFGVFVAAAITDYLDGYVARAWAQSSALGRMLDPI
ADKLLVAALLLMLAADRTIAGMSLWAAIVILCREVLVSGLREYLAELKVGLPVSRIAKWKTTVQLIALGFLVAGPAGEAV
LPGSLTAGIVLLWLAAALTLYTGWDYMRAGIRHVIDDPR
>Mature_199_residues
MNAVLPRRRSQAWTLANCLTYGRLVAVPVVVVLLFWPDEFAARWTAFGVFVAAAITDYLDGYVARAWAQSSALGRMLDPI
ADKLLVAALLLMLAADRTIAGMSLWAAIVILCREVLVSGLREYLAELKVGLPVSRIAKWKTTVQLIALGFLVAGPAGEAV
LPGSLTAGIVLLWLAAALTLYTGWDYMRAGIRHVIDDPR

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI188536108, Length=212, Percent_Identity=29.7169811320755, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1788220, Length=189, Percent_Identity=35.4497354497354, Blast_Score=99, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320059, Length=166, Percent_Identity=28.3132530120482, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21592; Mature: 21592

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVLPRRRSQAWTLANCLTYGRLVAVPVVVVLLFWPDEFAARWTAFGVFVAAAITDYLD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GYVARAWAQSSALGRMLDPIADKLLVAALLLMLAADRTIAGMSLWAAIVILCREVLVSGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
REYLAELKVGLPVSRIAKWKTTVQLIALGFLVAGPAGEAVLPGSLTAGIVLLWLAAALTL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YTGWDYMRAGIRHVIDDPR
HHCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNAVLPRRRSQAWTLANCLTYGRLVAVPVVVVLLFWPDEFAARWTAFGVFVAAAITDYLD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GYVARAWAQSSALGRMLDPIADKLLVAALLLMLAADRTIAGMSLWAAIVILCREVLVSGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
REYLAELKVGLPVSRIAKWKTTVQLIALGFLVAGPAGEAVLPGSLTAGIVLLWLAAALTL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YTGWDYMRAGIRHVIDDPR
HHCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA