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The map label for this gene is atpH1

Identifier: 218711026

GI number: 218711026

Start: 3292195

End: 3292728

Strand: Reverse

Name: atpH1

Synonym: VS_3155

Alternate gene names: 218711026

Gene position: 3292728-3292195 (Counterclockwise)

Preceding gene: 218711027

Following gene: 218711025

Centisome position: 99.8

GC content: 41.95

Gene sequence:

>534_bases
ATGTCTGATTTGACTACAATCGCACGCCCCTATGCTAAAGCAGCGTTTGACTTTGCGGTAGATAAAGGTGAGCTAGACCA
ATGGGGTCAAATGCTTACTTTTGCTGCCGAAGTGGCACAAAATGATGATGTTCACAATTTATTAAGCGGTTCTATGACTG
CTGAAAAATTAGCTGAAGTATTCATTGTAATTTGTGGCGAACAATTTGATGAATTCGGTCAGAACTTAATTAAAGTGATG
GCAGAGAATGGCCGCTTAATGGCTTTTCCTGATGTTTGTAAAGAGTTCTTTATACTCAAAAAAGAGTATGAGAAAGAGAT
CGACGTTGAAGTAACTTCAGCGGTAGAACTTTCTGAAGAACAACGTGCAGAGATCAGCAGCAAATTGGAACAGCGCTTAG
CGCGCAAAGTTCAGCTGAATTGCAGTATAGATGAGACTCTACTTAGTGGAGTTATTATTCGAGCCGGAGACCTAGTCATC
GATAACTCAGCGCGCAGTCGTTTAGACCGCCTGAGCGATGCATTGCAGTCTTAA

Upstream 100 bases:

>100_bases
AGCTGGTGCTGAGAAAATCCTTGAACGTACAATCGATAAAGATGTACACGATGATCTTCTTAACAACATTACTGCAAAAC
TTTAAAGCAAGGGGCTGTAT

Downstream 100 bases:

>100_bases
TGGGGATTGGAGCATGCAACTTAATTCCACTGAAATTAGCGATCTAATTAAACAACGTATTGAATCTTTCGACGTTGTTA
GTGAAGCTCGCAATGAAGGT

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta 1; F-type ATPase subunit delta 1; F-ATPase subunit delta 1

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MSDLTTIARPYAKAAFDFAVDKGELDQWGQMLTFAAEVAQNDDVHNLLSGSMTAEKLAEVFIVICGEQFDEFGQNLIKVM
AENGRLMAFPDVCKEFFILKKEYEKEIDVEVTSAVELSEEQRAEISSKLEQRLARKVQLNCSIDETLLSGVIIRAGDLVI
DNSARSRLDRLSDALQS

Sequences:

>Translated_177_residues
MSDLTTIARPYAKAAFDFAVDKGELDQWGQMLTFAAEVAQNDDVHNLLSGSMTAEKLAEVFIVICGEQFDEFGQNLIKVM
AENGRLMAFPDVCKEFFILKKEYEKEIDVEVTSAVELSEEQRAEISSKLEQRLARKVQLNCSIDETLLSGVIIRAGDLVI
DNSARSRLDRLSDALQS
>Mature_176_residues
SDLTTIARPYAKAAFDFAVDKGELDQWGQMLTFAAEVAQNDDVHNLLSGSMTAEKLAEVFIVICGEQFDEFGQNLIKVMA
ENGRLMAFPDVCKEFFILKKEYEKEIDVEVTSAVELSEEQRAEISSKLEQRLARKVQLNCSIDETLLSGVIIRAGDLVID
NSARSRLDRLSDALQS

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=173, Percent_Identity=26.0115606936416, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1790173, Length=177, Percent_Identity=58.7570621468927, Blast_Score=219, Evalue=8e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD1_VIBSL (B7VMZ9)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002418647.1
- ProteinModelPortal:   B7VMZ9
- SMR:   B7VMZ9
- GeneID:   7162593
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_3155
- HOGENOM:   HBG668108
- OMA:   ASLERKF
- ProtClustDB:   PRK05758
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19771; Mature: 19639

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLTTIARPYAKAAFDFAVDKGELDQWGQMLTFAAEVAQNDDVHNLLSGSMTAEKLAEV
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHH
FIVICGEQFDEFGQNLIKVMAENGRLMAFPDVCKEFFILKKEYEKEIDVEVTSAVELSEE
HHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QRAEISSKLEQRLARKVQLNCSIDETLLSGVIIRAGDLVIDNSARSRLDRLSDALQS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDLTTIARPYAKAAFDFAVDKGELDQWGQMLTFAAEVAQNDDVHNLLSGSMTAEKLAEV
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHH
FIVICGEQFDEFGQNLIKVMAENGRLMAFPDVCKEFFILKKEYEKEIDVEVTSAVELSEE
HHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QRAEISSKLEQRLARKVQLNCSIDETLLSGVIIRAGDLVIDNSARSRLDRLSDALQS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA