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The map label for this gene is rpoC [H]

Identifier: 218710878

GI number: 218710878

Start: 3120682

End: 3124917

Strand: Reverse

Name: rpoC [H]

Synonym: VS_2962

Alternate gene names: 218710878

Gene position: 3124917-3120682 (Counterclockwise)

Preceding gene: 218710879

Following gene: 218710876

Centisome position: 94.71

GC content: 46.18

Gene sequence:

>4236_bases
GTGAGCTCCTTTAACTCCTTACAGGAGCTGAACGTGAAAGACTTATTAAACTTTCTAAAAGCACAGCATAAGACCGAAGA
ATTTGATGCAATCAAAATCGGTCTATCTTCACCAGACACGATCCGTTCGTGGTCTTTTGGTGAAGTTAAAAAGCCAGAAA
CAATTAACTATCGTACGTTCAAACCTGAACGTGATGGTCTGTTCTGTGCACGTATTTTTGGTCCAGTTAAAGACTACGAA
TGTCTTTGTGGCAAATACAAGCGCCTGAAGCACCGTGGTGTTATCTGTGAGAAGTGTGGCGTTGAAGTTACACAAACTAA
AGTTCGTCGTGACCGTATGGGCCACATCGAGCTTGCTTCACCAGTTGCTCACATCTGGTTCCTAAAATCACTACCGTCTC
GTATCGGTCTACTAATGGATATCCCTCTGCGTGATATCGAACGTGTTCTTTACTTCGAAATGTACGTAGTAACTGAACCG
GGTATGACTGATCTAGAAAAATCTCAGATGCTTACTGAAGAAGAGTATCTGGATCGTCTAGAAGAGTGGGGTGACGAATT
CACTGCTAAGATGGGTGCTGAAGCGATCAAAGATCTGCTTTCAACAATGGACCTTCATCAAGAAGTGGAAGAAATGCGCG
AAGAGTTGGAAACAACTAACTCTGAAACTAAGCGTAAGAAAGTTACTAAGCGTTTGAAGCTAGTTGAAGCGTTCATTTCG
TCAGGCAACAAGCCTGAGTGGATGATCCTAACTGTACTTCCAGTGCTACCGCCAGATCTACGTCCTCTAGTACCACTAGA
TGGCGGTCGTTTTGCGACATCTGATCTGAACGACCTTTACCGTCGTGTGATCAACCGTAACAACCGTTTGAAGCGTCTTC
TAGAGCTAGCGGCTCCAGACATCATCGTACGTAACGAAAAGCGTATGCTGCAAGAGTCTGTTGATGCCCTTCTAGATAAC
GGTCGTCGCGGTCGTGCGATCACGGGTTCTAACAAGCGTCCTCTGAAATCTCTTGCTGATATGATCAAGGGTAAACAAGG
TCGTTTCCGTCAGAACCTTCTAGGTAAACGTGTAGACTACTCTGGCCGTTCTGTAATCACAGTTGGTCCATACCTTCGTC
TACATCAGTGTGGTCTTCCTAAGAAGATGGCACTTGAGCTATTTAAGCCGTTCATCTACAGCAAGCTAGAAACTCGTGGC
ATGGCTACGACAATCAAAGCTGCTAAGAAAATGGTAGAGCGCGAAGAAGCGATCGTTTGGGATATCCTAGACGAAGTTAT
CCGTGAACACCCAGTACTGCTTAACCGTGCACCTACACTTCACCGTCTAGGTATCCAAGCGTTTGAACCAGTACTAATCG
AAGGTAAAGCGATTCAGCTTCACCCACTAGTGTGTGCGGCATACAACGCCGACTTCGATGGTGACCAAATGGCTGTACAC
GTGCCTCTAACTCTAGAAGCACAGCTTGAAGCTCGTACCCTAATGATGTCGACGAATAACATTCTGTCGCCAGCATCAGG
TGATCCAATCATCGTACCTTCTCAGGACGTTGTATTGGGTCTTTACTACATGACACGTGACAAGATCAACGTGAAAGGTG
AAGGTATGTACCTTGCTGGCCCTGCTGAGGCTGAAAAGGCATACCGTACTAAGACTGCTGAGCTACACGCTCGCGTTAAA
GTACGTATCACTGAAACTGTAGTAGATGAAGACGGCAATAGCACAACGAATACTGGTCTAGTTGATACGACTGTAGGTCG
TGCAATGCTATGGCAGATCGTTCCTGCTGGCCTACCGTACAGCATCGTTAACCAAAAGTTAGGTAAGAAGCAGATCTCTA
CTCTTCTTAACGAGTGTTACCGTAAGCTTGGTCTAAAAGATACAGTAGTATTTGCTGACCAAATCATGTACGCAGGTTTC
GCATACGCGGCACTTTCTGGTGTTTCTGTAGGTATCAACGATATGGTTGTTCCTCAAGCGAAATACGATGAAATTGAATC
TGCTGAAGAAGAAGTTCGTGAAATCCAAGAGCAATTCCAATCAGGTCTTGTTACTGCGGGTGAGCGTTACAACAAAGTTA
TCGATATCTGGGCATCTACGAATGACCGCGTTGCGAAAGCAATGATGGATAACCTATCTTCTGAAACAGTTATCAACCGT
GACGGCGAAGAAGAACAGCAAGAATCGTTCAACAGCATCTACATGATGGCCGACTCGGGCGCACGTGGTTCTGCAGCTCA
GATTCGTCAGCTAGCAGGTATGCGTGGTCTGATGGCGCGTCCAGATGGTTCAATCATCGAAACGCCGATCACAGCGAACT
TTAAAGAAGGTCTAAACGTCCTTCAGTACTTTATCTCAACGCACGGTGCTCGTAAGGGTCTTGCGGATACAGCACTGAAA
ACAGCAAACTCGGGTTACCTAACTCGTCGTCTAGTAGACGTTGCTCAAGACGTTGTAGTACACGAACATGACTGTGGCAC
GCATGAAGGTATCGACATGATGCCTCACATCGAAGGTGGTGACGTTAAAGTTGCACTTTCTGAGCTTGCTCTAGGTCGTG
TAGTAGCTGAAGACGTTCTTAAGCCTGGTACTGAAGATGTACTGATTCCACGTAATACTCTGATTGATGAGAAGTGGTGT
CAAATCATGGAAGACAACTCAGTAGATAGCATGAAAGTGCGCTCTGTTGTTACCTGTGATGCAGACTTCGGTTGTTGTGC
ACAGTGTTACGGTCGTGACCTAGCACGTGGTCACCTAGTGAATCAAGGTGAAGCAGTTGGTGTTATCGCTGCACAATCTA
TCGGTGAACCGGGTACACAGCTAACGATGCGTACGTTCCACATCGGTGGTGCGGCATCTACTGCAGCAGCAGAGAACAGC
ATCCAAGCTAAGACAACTGGTACTGTGAAACTTCACAATGCTAAGTTCGTAGTTAACAAAGATAAGAAACTGGTTATCAC
TTCTCGTGCATCTGAGATGACGATTATTGATGAATTCGGCCGCACTAAAGAGAAGCACAAACTTCCTTACGGTTCGATGC
TAACCAAAGGCGACAACGCAGCAGTTACTGCTGGTGAAGTTGTAGCTAACTGGGAAGCGCATACCATGCCAATCATCACT
GAAGTGGCAGGTCGTATCCAATTCGTAGATATGATCGATGGTATTACAGTTTCTCGTCAAACTGACGATCTAACGGGTCT
TTCTTCAAGTGAAGTAACAGACGCAGCAGCTCGCCCAGCAGCAGGTAAAGATATGCGTCCAGCTATCAAACTTGTTGATG
AGCAAGGTAACGACGTAATGATCCCTGGTACTGATATGCCAGCTCACTACTTCCTACCTGGCAAAGCGATTGTAAACATC
GAAGATGGCGCTGAAGTTGGCATTGGTGACACACTATCTCGTATCCCTCAAAAATCGAGCGGAAACAAAGATATCACCGG
TGGTCTACCACGCGTAGCTGACCTATTCGAAGCTCGTAAGCCTAAAGAGCCTGCGATCCTTGCTGAGCACACAGGTACTG
TGTCTTTCGGTAAAGAAACGAAAGGTAAGCGTCGTCTAGTAATCACTCGTGAAGGCGGTGACGCTTACGAAGAGATGATT
CCTAAGCATCGTCAATTGAACGTGTTCGAAGGTGAGAAGATTGAACGTGGTGATGTAATCGCCGACGGTCCTGAAACTCC
ACACGATATCCTGCGTCTACGTGGTATCCACGCAGTAACTCAGTACATCGCGAACGAAGTTCAAGAAGTTTACCGCTTAC
AAGGCGTAAAGATTAACGATAAGCACATCGAGACTATCGTTCGTCAAATGCTACGTAAGTGTACAATCACTCATTCTGGT
GACTCTCCGTTCCTACCTGGCGAACAAGTTGAGTACCACAATGTTAAGATTGCTAACCGTAAGCTAGAAGCTGAAGGTAA
AGAACTAGTACGTTTCGAACGTGACCTACTAGGTATTACTAAAGCATCTCTTGCAACTGAGTCATTCATCTCAGCTGCAT
CGTTCCAAGAAACGACTCGCGTACTAACAGAAGCTGCGGTTTCTGGTAAGCGTGATGACCTTCGCGGCCTGAAAGAGAAC
GTAATTGTTGGTCGTCTGATCCCAGCTGGTACTGGTTTCGCATACCACCAAGAGCGTCAAAAGCAACGTGAAGAAGAGCA
AGAAGGTCCTTCAGCTGAACAAGCTACTGACAATCTAGCAGCACTTCTAAACGCTGGTTTCTCTTCAGAAGAGTAA

Upstream 100 bases:

>100_bases
TCGCTCGCTAGGTATCAACATCGAGCTAGAAGACGAAGAGTAATCCCTCTTTTTTATAAAGAAGATTGGATTACTTGGTA
AAGGGGGCTCACTTTAGTCG

Downstream 100 bases:

>100_bases
GCTCTACGAGTAGTTTCTAAGAGATAAGAAAAAGGCACCTTCGGGTGCCTTTTTTGTATCTGGCGTATTGGTATTTAGCT
ATGACTTATAAAGTGATAGG

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1411; Mature: 1410

Protein sequence:

>1411_residues
MSSFNSLQELNVKDLLNFLKAQHKTEEFDAIKIGLSSPDTIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYE
CLCGKYKRLKHRGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSLPSRIGLLMDIPLRDIERVLYFEMYVVTEP
GMTDLEKSQMLTEEEYLDRLEEWGDEFTAKMGAEAIKDLLSTMDLHQEVEEMREELETTNSETKRKKVTKRLKLVEAFIS
SGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELAAPDIIVRNEKRMLQESVDALLDN
GRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYSKLETRG
MATTIKAAKKMVEREEAIVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVH
VPLTLEAQLEARTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTRDKINVKGEGMYLAGPAEAEKAYRTKTAELHARVK
VRITETVVDEDGNSTTNTGLVDTTVGRAMLWQIVPAGLPYSIVNQKLGKKQISTLLNECYRKLGLKDTVVFADQIMYAGF
AYAALSGVSVGINDMVVPQAKYDEIESAEEEVREIQEQFQSGLVTAGERYNKVIDIWASTNDRVAKAMMDNLSSETVINR
DGEEEQQESFNSIYMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFKEGLNVLQYFISTHGARKGLADTALK
TANSGYLTRRLVDVAQDVVVHEHDCGTHEGIDMMPHIEGGDVKVALSELALGRVVAEDVLKPGTEDVLIPRNTLIDEKWC
QIMEDNSVDSMKVRSVVTCDADFGCCAQCYGRDLARGHLVNQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAAENS
IQAKTTGTVKLHNAKFVVNKDKKLVITSRASEMTIIDEFGRTKEKHKLPYGSMLTKGDNAAVTAGEVVANWEAHTMPIIT
EVAGRIQFVDMIDGITVSRQTDDLTGLSSSEVTDAAARPAAGKDMRPAIKLVDEQGNDVMIPGTDMPAHYFLPGKAIVNI
EDGAEVGIGDTLSRIPQKSSGNKDITGGLPRVADLFEARKPKEPAILAEHTGTVSFGKETKGKRRLVITREGGDAYEEMI
PKHRQLNVFEGEKIERGDVIADGPETPHDILRLRGIHAVTQYIANEVQEVYRLQGVKINDKHIETIVRQMLRKCTITHSG
DSPFLPGEQVEYHNVKIANRKLEAEGKELVRFERDLLGITKASLATESFISAASFQETTRVLTEAAVSGKRDDLRGLKEN
VIVGRLIPAGTGFAYHQERQKQREEEQEGPSAEQATDNLAALLNAGFSSEE

Sequences:

>Translated_1411_residues
MSSFNSLQELNVKDLLNFLKAQHKTEEFDAIKIGLSSPDTIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYE
CLCGKYKRLKHRGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSLPSRIGLLMDIPLRDIERVLYFEMYVVTEP
GMTDLEKSQMLTEEEYLDRLEEWGDEFTAKMGAEAIKDLLSTMDLHQEVEEMREELETTNSETKRKKVTKRLKLVEAFIS
SGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELAAPDIIVRNEKRMLQESVDALLDN
GRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYSKLETRG
MATTIKAAKKMVEREEAIVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVH
VPLTLEAQLEARTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTRDKINVKGEGMYLAGPAEAEKAYRTKTAELHARVK
VRITETVVDEDGNSTTNTGLVDTTVGRAMLWQIVPAGLPYSIVNQKLGKKQISTLLNECYRKLGLKDTVVFADQIMYAGF
AYAALSGVSVGINDMVVPQAKYDEIESAEEEVREIQEQFQSGLVTAGERYNKVIDIWASTNDRVAKAMMDNLSSETVINR
DGEEEQQESFNSIYMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFKEGLNVLQYFISTHGARKGLADTALK
TANSGYLTRRLVDVAQDVVVHEHDCGTHEGIDMMPHIEGGDVKVALSELALGRVVAEDVLKPGTEDVLIPRNTLIDEKWC
QIMEDNSVDSMKVRSVVTCDADFGCCAQCYGRDLARGHLVNQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAAENS
IQAKTTGTVKLHNAKFVVNKDKKLVITSRASEMTIIDEFGRTKEKHKLPYGSMLTKGDNAAVTAGEVVANWEAHTMPIIT
EVAGRIQFVDMIDGITVSRQTDDLTGLSSSEVTDAAARPAAGKDMRPAIKLVDEQGNDVMIPGTDMPAHYFLPGKAIVNI
EDGAEVGIGDTLSRIPQKSSGNKDITGGLPRVADLFEARKPKEPAILAEHTGTVSFGKETKGKRRLVITREGGDAYEEMI
PKHRQLNVFEGEKIERGDVIADGPETPHDILRLRGIHAVTQYIANEVQEVYRLQGVKINDKHIETIVRQMLRKCTITHSG
DSPFLPGEQVEYHNVKIANRKLEAEGKELVRFERDLLGITKASLATESFISAASFQETTRVLTEAAVSGKRDDLRGLKEN
VIVGRLIPAGTGFAYHQERQKQREEEQEGPSAEQATDNLAALLNAGFSSEE
>Mature_1410_residues
SSFNSLQELNVKDLLNFLKAQHKTEEFDAIKIGLSSPDTIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYEC
LCGKYKRLKHRGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSLPSRIGLLMDIPLRDIERVLYFEMYVVTEPG
MTDLEKSQMLTEEEYLDRLEEWGDEFTAKMGAEAIKDLLSTMDLHQEVEEMREELETTNSETKRKKVTKRLKLVEAFISS
GNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELAAPDIIVRNEKRMLQESVDALLDNG
RRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYSKLETRGM
ATTIKAAKKMVEREEAIVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHV
PLTLEAQLEARTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTRDKINVKGEGMYLAGPAEAEKAYRTKTAELHARVKV
RITETVVDEDGNSTTNTGLVDTTVGRAMLWQIVPAGLPYSIVNQKLGKKQISTLLNECYRKLGLKDTVVFADQIMYAGFA
YAALSGVSVGINDMVVPQAKYDEIESAEEEVREIQEQFQSGLVTAGERYNKVIDIWASTNDRVAKAMMDNLSSETVINRD
GEEEQQESFNSIYMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFKEGLNVLQYFISTHGARKGLADTALKT
ANSGYLTRRLVDVAQDVVVHEHDCGTHEGIDMMPHIEGGDVKVALSELALGRVVAEDVLKPGTEDVLIPRNTLIDEKWCQ
IMEDNSVDSMKVRSVVTCDADFGCCAQCYGRDLARGHLVNQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAAENSI
QAKTTGTVKLHNAKFVVNKDKKLVITSRASEMTIIDEFGRTKEKHKLPYGSMLTKGDNAAVTAGEVVANWEAHTMPIITE
VAGRIQFVDMIDGITVSRQTDDLTGLSSSEVTDAAARPAAGKDMRPAIKLVDEQGNDVMIPGTDMPAHYFLPGKAIVNIE
DGAEVGIGDTLSRIPQKSSGNKDITGGLPRVADLFEARKPKEPAILAEHTGTVSFGKETKGKRRLVITREGGDAYEEMIP
KHRQLNVFEGEKIERGDVIADGPETPHDILRLRGIHAVTQYIANEVQEVYRLQGVKINDKHIETIVRQMLRKCTITHSGD
SPFLPGEQVEYHNVKIANRKLEAEGKELVRFERDLLGITKASLATESFISAASFQETTRVLTEAAVSGKRDDLRGLKENV
IVGRLIPAGTGFAYHQERQKQREEEQEGPSAEQATDNLAALLNAGFSSEE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=932, Percent_Identity=25.8583690987124, Blast_Score=211, Evalue=4e-54,
Organism=Homo sapiens, GI39725938, Length=308, Percent_Identity=30.8441558441558, Blast_Score=133, Evalue=1e-30,
Organism=Homo sapiens, GI103471997, Length=585, Percent_Identity=25.4700854700855, Blast_Score=122, Evalue=2e-27,
Organism=Escherichia coli, GI2367335, Length=1405, Percent_Identity=81.067615658363, Blast_Score=2351, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=660, Percent_Identity=28.3333333333333, Blast_Score=188, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI25145495, Length=672, Percent_Identity=26.6369047619048, Blast_Score=183, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6320061, Length=883, Percent_Identity=24.0090600226501, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324690, Length=690, Percent_Identity=25.2173913043478, Blast_Score=168, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6324917, Length=284, Percent_Identity=27.4647887323944, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI17530899, Length=907, Percent_Identity=25.3583241455347, Blast_Score=202, Evalue=2e-51,
Organism=Drosophila melanogaster, GI281360912, Length=516, Percent_Identity=25.3875968992248, Blast_Score=141, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 156497; Mature: 156366

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFNSLQELNVKDLLNFLKAQHKTEEFDAIKIGLSSPDTIRSWSFGEVKKPETINYRTF
CCCCHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEC
KPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRDRMGHIELAS
CCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHH
PVAHIWFLKSLPSRIGLLMDIPLRDIERVLYFEMYVVTEPGMTDLEKSQMLTEEEYLDRL
HHHHHHHHHHHHHHCCEEEECCHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHH
EEWGDEFTAKMGAEAIKDLLSTMDLHQEVEEMREELETTNSETKRKKVTKRLKLVEAFIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELAAPD
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
IIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDY
EEEECHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVITVGPYLRLHQCGLPKKMALELFKPFIYSKLETRGMATTIKAAKKMVEREEAIVW
CCCEEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVH
HHHHHHHHHCCEEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEE
VPLTLEAQLEARTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTRDKINVKGEGMYLAG
EEEEEECCCCCEEEEEECCCCCCCCCCCEEEECCCCCEEEEEEEECCCEEECCCCEEEEC
PAEAEKAYRTKTAELHARVKVRITETVVDEDGNSTTNTGLVDTTVGRAMLWQIVPAGLPY
CHHHHHHHHHHHHHEEEEEEEEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCH
SIVNQKLGKKQISTLLNECYRKLGLKDTVVFADQIMYAGFAYAALSGVSVGINDMVVPQA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCEECCCC
KYDEIESAEEEVREIQEQFQSGLVTAGERYNKVIDIWASTNDRVAKAMMDNLSSETVINR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCEECC
DGEEEQQESFNSIYMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFKEGLNV
CCCHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHH
LQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDVVVHEHDCGTHEGIDMMPHIEGG
HHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCC
DVKVALSELALGRVVAEDVLKPGTEDVLIPRNTLIDEKWCQIMEDNSVDSMKVRSVVTCD
CEEEEHHHHHHHHHHHHHHHCCCCCCEEECCHHHCCHHHHHHHCCCCCCCEEEEEEEEEC
ADFGCCAQCYGRDLARGHLVNQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAAENS
CCCHHHHHHHCCHHHCCCCCCCCCEEEEEEHHCCCCCCCEEEEEEEEECCCCHHHHHCCC
IQAKTTGTVKLHNAKFVVNKDKKLVITSRASEMTIIDEFGRTKEKHKLPYGSMLTKGDNA
CEEEECCEEEEECEEEEEECCCEEEEEECCCCEEHHHHHCCCHHHHCCCCCHHEECCCCC
AVTAGEVVANWEAHTMPIITEVAGRIQFVDMIDGITVSRQTDDLTGLSSSEVTDAAARPA
EEECCHHEECCCCCCCHHHHHHHHHEEEEHHHCCEEEECCCCCCCCCCCCCCHHHHCCCC
AGKDMRPAIKLVDEQGNDVMIPGTDMPAHYFLPGKAIVNIEDGAEVGIGDTLSRIPQKSS
CCCCCCHHHHHHCCCCCEEEECCCCCCCEEEECCCEEEEECCCCCCCCCHHHHHCCCCCC
GNKDITGGLPRVADLFEARKPKEPAILAEHTGTVSFGKETKGKRRLVITREGGDAYEEMI
CCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCEECCCCCCCCEEEEEEECCCCHHHHHC
PKHRQLNVFEGEKIERGDVIADGPETPHDILRLRGIHAVTQYIANEVQEVYRLQGVKIND
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
KHIETIVRQMLRKCTITHSGDSPFLPGEQVEYHNVKIANRKLEAEGKELVRFERDLLGIT
HHHHHHHHHHHHHCEEEECCCCCCCCCCCEEECCEEEECCCCCCCHHHHHHHHHHHHHHH
KASLATESFISAASFQETTRVLTEAAVSGKRDDLRGLKENVIVGRLIPAGTGFAYHQERQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHH
KQREEEQEGPSAEQATDNLAALLNAGFSSEE
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SSFNSLQELNVKDLLNFLKAQHKTEEFDAIKIGLSSPDTIRSWSFGEVKKPETINYRTF
CCCHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEC
KPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRDRMGHIELAS
CCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHH
PVAHIWFLKSLPSRIGLLMDIPLRDIERVLYFEMYVVTEPGMTDLEKSQMLTEEEYLDRL
HHHHHHHHHHHHHHCCEEEECCHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHH
EEWGDEFTAKMGAEAIKDLLSTMDLHQEVEEMREELETTNSETKRKKVTKRLKLVEAFIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELAAPD
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
IIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDY
EEEECHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCC
SGRSVITVGPYLRLHQCGLPKKMALELFKPFIYSKLETRGMATTIKAAKKMVEREEAIVW
CCCEEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVH
HHHHHHHHHCCEEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEE
VPLTLEAQLEARTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTRDKINVKGEGMYLAG
EEEEEECCCCCEEEEEECCCCCCCCCCCEEEECCCCCEEEEEEEECCCEEECCCCEEEEC
PAEAEKAYRTKTAELHARVKVRITETVVDEDGNSTTNTGLVDTTVGRAMLWQIVPAGLPY
CHHHHHHHHHHHHHEEEEEEEEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCH
SIVNQKLGKKQISTLLNECYRKLGLKDTVVFADQIMYAGFAYAALSGVSVGINDMVVPQA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCEECCCC
KYDEIESAEEEVREIQEQFQSGLVTAGERYNKVIDIWASTNDRVAKAMMDNLSSETVINR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCEECC
DGEEEQQESFNSIYMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFKEGLNV
CCCHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHH
LQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDVVVHEHDCGTHEGIDMMPHIEGG
HHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCC
DVKVALSELALGRVVAEDVLKPGTEDVLIPRNTLIDEKWCQIMEDNSVDSMKVRSVVTCD
CEEEEHHHHHHHHHHHHHHHCCCCCCEEECCHHHCCHHHHHHHCCCCCCCEEEEEEEEEC
ADFGCCAQCYGRDLARGHLVNQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAAENS
CCCHHHHHHHCCHHHCCCCCCCCCEEEEEEHHCCCCCCCEEEEEEEEECCCCHHHHHCCC
IQAKTTGTVKLHNAKFVVNKDKKLVITSRASEMTIIDEFGRTKEKHKLPYGSMLTKGDNA
CEEEECCEEEEECEEEEEECCCEEEEEECCCCEEHHHHHCCCHHHHCCCCCHHEECCCCC
AVTAGEVVANWEAHTMPIITEVAGRIQFVDMIDGITVSRQTDDLTGLSSSEVTDAAARPA
EEECCHHEECCCCCCCHHHHHHHHHEEEEHHHCCEEEECCCCCCCCCCCCCCHHHHCCCC
AGKDMRPAIKLVDEQGNDVMIPGTDMPAHYFLPGKAIVNIEDGAEVGIGDTLSRIPQKSS
CCCCCCHHHHHHCCCCCEEEECCCCCCCEEEECCCEEEEECCCCCCCCCHHHHHCCCCCC
GNKDITGGLPRVADLFEARKPKEPAILAEHTGTVSFGKETKGKRRLVITREGGDAYEEMI
CCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCEECCCCCCCCEEEEEEECCCCHHHHHC
PKHRQLNVFEGEKIERGDVIADGPETPHDILRLRGIHAVTQYIANEVQEVYRLQGVKIND
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
KHIETIVRQMLRKCTITHSGDSPFLPGEQVEYHNVKIANRKLEAEGKELVRFERDLLGIT
HHHHHHHHHHHHHCEEEECCCCCCCCCCCEEECCEEEECCCCCCCHHHHHHHHHHHHHHH
KASLATESFISAASFQETTRVLTEAAVSGKRDDLRGLKENVIVGRLIPAGTGFAYHQERQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHH
KQREEEQEGPSAEQATDNLAALLNAGFSSEE
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA