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The map label for this gene is nudC

Identifier: 218710876

GI number: 218710876

Start: 3118879

End: 3119688

Strand: Reverse

Name: nudC

Synonym: VS_2960

Alternate gene names: 218710876

Gene position: 3119688-3118879 (Counterclockwise)

Preceding gene: 218710878

Following gene: 218710875

Centisome position: 94.56

GC content: 45.93

Gene sequence:

>810_bases
ATGTTAAAAAAAAGTGATAACAAAATGACAGATCAAGCTTATTGGTGCGTCGTTTCTGGTAGTGATATTTGGGTTAATGA
TGATCAGTTTCCTTTTGGCTCTGCTGAAGAGCTAGGACTGAGTGTTGAGCATGCAATCTGTATTGGTCAGCATCAAGGTC
GTAAGGTTTATTGGCTCAACGATTGCGATGTGGAGATTGAACTGAGCATGGTCAGCCTCAGAGATTTGCTTCACTGGCCT
GAATCAAGTTTTCTGATCGCAAGCAAAGCTATCCAGTATGGGCACATGACACAAAGTATGCGTTTTTGTCCTCAGTGCGG
CGGTCGTAATCATCTCAATCATAATCAGGTGGCGATGCAATGTGGAGACTGCCGAACGCTTCATTACCCTCGTATCTTCC
CGTGCATCATTGTCGCTGTACGAAACGACAACAAGATATTACTTGCGCAGCACCCAAGGCATAAAACGGGTATGTACACG
GTAATAGCGGGCTTCCTAGAGGTTGGAGAAACCCTAGAGCAGTGTGTGGCGCGAGAAGTCAAAGAAGAAACGGGTATCGA
CGTGAGTAACATTCGTTACTTTGGTAGCCAGCCATGGGCGTTTCCATCGAGTATGATGATGGCCTTTCTTGCTGACTATG
CTGGTGGAACGCTCAAACCTGATTACAGTGAACTGTCAGATGCCCAATGGTTTGACGTAACAAGCCTACCTGATGTTGCT
CCAGTCGGAACGATTGCGAGACAATTGATTGAGAATACAGTCGATGACATAAGGAAAGCCAGCGTCGCGGAGCAAGAACT
AGAACATTAA

Upstream 100 bases:

>100_bases
AGCTACTAAAAGTAATAGCTTGAAATATTCTCTGCTACAACTCTAGTATGAAATTAGATTGCCAGTAAAATGAACGAACT
GCAAGCAATGAGGCATAGGG

Downstream 100 bases:

>100_bases
ATTACCTGTGATAGTATTTGGCCTATGGGTGGTCAAGCACTAAAAAAAACCCTCCACAAGTGGAGGGGGTAAGTAAGATG
TCGTTATGAGATGCTGAGTA

Product: NADH pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MLKKSDNKMTDQAYWCVVSGSDIWVNDDQFPFGSAEELGLSVEHAICIGQHQGRKVYWLNDCDVEIELSMVSLRDLLHWP
ESSFLIASKAIQYGHMTQSMRFCPQCGGRNHLNHNQVAMQCGDCRTLHYPRIFPCIIVAVRNDNKILLAQHPRHKTGMYT
VIAGFLEVGETLEQCVAREVKEETGIDVSNIRYFGSQPWAFPSSMMMAFLADYAGGTLKPDYSELSDAQWFDVTSLPDVA
PVGTIARQLIENTVDDIRKASVAEQELEH

Sequences:

>Translated_269_residues
MLKKSDNKMTDQAYWCVVSGSDIWVNDDQFPFGSAEELGLSVEHAICIGQHQGRKVYWLNDCDVEIELSMVSLRDLLHWP
ESSFLIASKAIQYGHMTQSMRFCPQCGGRNHLNHNQVAMQCGDCRTLHYPRIFPCIIVAVRNDNKILLAQHPRHKTGMYT
VIAGFLEVGETLEQCVAREVKEETGIDVSNIRYFGSQPWAFPSSMMMAFLADYAGGTLKPDYSELSDAQWFDVTSLPDVA
PVGTIARQLIENTVDDIRKASVAEQELEH
>Mature_269_residues
MLKKSDNKMTDQAYWCVVSGSDIWVNDDQFPFGSAEELGLSVEHAICIGQHQGRKVYWLNDCDVEIELSMVSLRDLLHWP
ESSFLIASKAIQYGHMTQSMRFCPQCGGRNHLNHNQVAMQCGDCRTLHYPRIFPCIIVAVRNDNKILLAQHPRHKTGMYT
VIAGFLEVGETLEQCVAREVKEETGIDVSNIRYFGSQPWAFPSSMMMAFLADYAGGTLKPDYSELSDAQWFDVTSLPDVA
PVGTIARQLIENTVDDIRKASVAEQELEH

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Homo sapiens, GI13899267, Length=173, Percent_Identity=36.4161849710983, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI50593112, Length=204, Percent_Identity=29.9019607843137, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI48994995, Length=244, Percent_Identity=43.0327868852459, Blast_Score=214, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI212645999, Length=188, Percent_Identity=31.3829787234043, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71986510, Length=188, Percent_Identity=31.3829787234043, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321371, Length=174, Percent_Identity=32.7586206896552, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUDC_VIBSL (B7VM66)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002418497.1
- ProteinModelPortal:   B7VM66
- GeneID:   7162443
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2960
- HOGENOM:   HBG736436
- OMA:   SPCIIVA
- ProtClustDB:   PRK00241
- HAMAP:   MF_00297
- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase; SSF55811 NUDIX_hydrolase

EC number: =3.6.1.22

Molecular weight: Translated: 30335; Mature: 30335

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKSDNKMTDQAYWCVVSGSDIWVNDDQFPFGSAEELGLSVEHAICIGQHQGRKVYWLN
CCCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCHHHHCCCHHHEEEECCCCCCEEEEEE
DCDVEIELSMVSLRDLLHWPESSFLIASKAIQYGHMTQSMRFCPQCGGRNHLNHNQVAMQ
CCCEEEEEHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEE
CGDCRTLHYPRIFPCIIVAVRNDNKILLAQHPRHKTGMYTVIAGFLEVGETLEQCVAREV
CCCCCEECCCCEEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KEETGIDVSNIRYFGSQPWAFPSSMMMAFLADYAGGTLKPDYSELSDAQWFDVTSLPDVA
HHHHCCCHHHEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEECCCCCCCC
PVGTIARQLIENTVDDIRKASVAEQELEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKKSDNKMTDQAYWCVVSGSDIWVNDDQFPFGSAEELGLSVEHAICIGQHQGRKVYWLN
CCCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCHHHHCCCHHHEEEECCCCCCEEEEEE
DCDVEIELSMVSLRDLLHWPESSFLIASKAIQYGHMTQSMRFCPQCGGRNHLNHNQVAMQ
CCCEEEEEHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEE
CGDCRTLHYPRIFPCIIVAVRNDNKILLAQHPRHKTGMYTVIAGFLEVGETLEQCVAREV
CCCCCEECCCCEEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KEETGIDVSNIRYFGSQPWAFPSSMMMAFLADYAGGTLKPDYSELSDAQWFDVTSLPDVA
HHHHCCCHHHEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEECCCCCCCC
PVGTIARQLIENTVDDIRKASVAEQELEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA