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The map label for this gene is zntR [H]

Identifier: 218710866

GI number: 218710866

Start: 3108706

End: 3109170

Strand: Reverse

Name: zntR [H]

Synonym: VS_2950

Alternate gene names: 218710866

Gene position: 3109170-3108706 (Counterclockwise)

Preceding gene: 218710869

Following gene: 218710855

Centisome position: 94.24

GC content: 42.37

Gene sequence:

>465_bases
ATGGACGGAACAGTAGGAAAAACCATGTTTCAGATCGGTGAATTAGCGAAAAGATGCGGTGTGACAGCCGATACCTTGCG
GTTTTATGAAAAAAGTAACCTGATTGCTCCTGCTAGTCGCAGTGACTCAGGATATCGCTTATATGATGAAAACAATCAAA
AACAGGTGACCTTTATTCTTAAATCTAAAGCGTTAGGGCTGAGTTTAGATGAAATTAAGGAATTGCTCGAGATTCGCTTG
GAAGCAACGCAGCACAGTTGCTCGGAAGTGAAAGCCATCACAACGGCAAAGCTGACACTTATTGATGAAAAAATCAGTGA
ACTTGGCAGAATACGAACGGCATTAAAGAAGATTAATGATGCTTGCTGCGGTCATGTAGATGACGATGCGAGCCATTGTT
CTATCTTAGGTGCTTTGGCGAGCGAAGATAAACAAAGCTCATGCTGTGCTGCTGATGGTAAATAG

Upstream 100 bases:

>100_bases
AATTTATTACAAAAAAGCTCGCGCAATCGTTTGGCATCTCAAAATTAATTATGAAAAGTGCCATTTCAGCCTGAAAAGTA
ACGATAAGGTTAATTGTGGA

Downstream 100 bases:

>100_bases
CTGAGAAGGTCCCCCGTTAGGGAGAGAGGTTTACTACGGTTGATAACCCTAGGAAGCTTGCAGTATTTTGGCTCTTAGTT
GAGCGTCAATTTTTAAAGTG

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MDGTVGKTMFQIGELAKRCGVTADTLRFYEKSNLIAPASRSDSGYRLYDENNQKQVTFILKSKALGLSLDEIKELLEIRL
EATQHSCSEVKAITTAKLTLIDEKISELGRIRTALKKINDACCGHVDDDASHCSILGALASEDKQSSCCAADGK

Sequences:

>Translated_154_residues
MDGTVGKTMFQIGELAKRCGVTADTLRFYEKSNLIAPASRSDSGYRLYDENNQKQVTFILKSKALGLSLDEIKELLEIRL
EATQHSCSEVKAITTAKLTLIDEKISELGRIRTALKKINDACCGHVDDDASHCSILGALASEDKQSSCCAADGK
>Mature_154_residues
MDGTVGKTMFQIGELAKRCGVTADTLRFYEKSNLIAPASRSDSGYRLYDENNQKQVTFILKSKALGLSLDEIKELLEIRL
EATQHSCSEVKAITTAKLTLIDEKISELGRIRTALKKINDACCGHVDDDASHCSILGALASEDKQSSCCAADGK

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=131, Percent_Identity=41.9847328244275, Blast_Score=120, Evalue=4e-29,
Organism=Escherichia coli, GI1786695, Length=140, Percent_Identity=32.8571428571429, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16759; Mature: 16759

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGTVGKTMFQIGELAKRCGVTADTLRFYEKSNLIAPASRSDSGYRLYDENNQKQVTFIL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEECCCCCCCCCEEEECCCCCEEEEEEE
KSKALGLSLDEIKELLEIRLEATQHSCSEVKAITTAKLTLIDEKISELGRIRTALKKIND
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ACCGHVDDDASHCSILGALASEDKQSSCCAADGK
HHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDGTVGKTMFQIGELAKRCGVTADTLRFYEKSNLIAPASRSDSGYRLYDENNQKQVTFIL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEECCCCCCCCCEEEECCCCCEEEEEEE
KSKALGLSLDEIKELLEIRLEATQHSCSEVKAITTAKLTLIDEKISELGRIRTALKKIND
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ACCGHVDDDASHCSILGALASEDKQSSCCAADGK
HHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]