Click here to switch to the map view.

The map label for this gene is fis [H]

Identifier: 218710864

GI number: 218710864

Start: 3107239

End: 3107535

Strand: Direct

Name: fis [H]

Synonym: VS_2948

Alternate gene names: 218710864

Gene position: 3107239-3107535 (Clockwise)

Preceding gene: 218710863

Following gene: 218710865

Centisome position: 94.18

GC content: 40.74

Gene sequence:

>297_bases
ATGTTCGAACAAAATCTGACTTCAGAAGCATTGACAGTAACTACAGTTACATCACAAGACCAAATCACGCAGAAGCCACT
ACGTGACTCAGTTAAAGCATCATTGAAAAATTACCTTGCTCAATTAAACGGTCAAGAAGTCAGCGAGTTATACGAATTAG
TATTAGCTGAAGTTGAACAGCCACTACTAGACACTATCATGCAGTACACTCGCGGTAACCAAACTCGCGCAGCAACCATG
ATGGGTATTAACCGCGGTACTCTTCGCAAGAAACTTAAAAAATACGGCATGAACTAA

Upstream 100 bases:

>100_bases
GTACCTTCAACGCATTCGAAGCAGGTGATCTGCAGCTTGAAGCGCTAGAAGGTTTTTTTGATAACGTTGCACCATAATTA
CGAGAAGAGCTAGACCGAAT

Downstream 100 bases:

>100_bases
TCGTTCTTTCGTAATTTATTGAATTAGAAGCCGAGCTCTTTATTGAACTCGGCTTTTTTTTGTTTATATGGCAACAAGCG
AACAATTATCAATCAATTAA

Product: DNA-binding protein Fis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 98; Mature: 98

Protein sequence:

>98_residues
MFEQNLTSEALTVTTVTSQDQITQKPLRDSVKASLKNYLAQLNGQEVSELYELVLAEVEQPLLDTIMQYTRGNQTRAATM
MGINRGTLRKKLKKYGMN

Sequences:

>Translated_98_residues
MFEQNLTSEALTVTTVTSQDQITQKPLRDSVKASLKNYLAQLNGQEVSELYELVLAEVEQPLLDTIMQYTRGNQTRAATM
MGINRGTLRKKLKKYGMN
>Mature_98_residues
MFEQNLTSEALTVTTVTSQDQITQKPLRDSVKASLKNYLAQLNGQEVSELYELVLAEVEQPLLDTIMQYTRGNQTRAATM
MGINRGTLRKKLKKYGMN

Specific function: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters [H]

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family [H]

Homologues:

Organism=Escherichia coli, GI1789661, Length=98, Percent_Identity=82.6530612244898, Blast_Score=172, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197 [H]

Pfam domain/function: PF02954 HTH_8 [H]

EC number: NA

Molecular weight: Translated: 11098; Mature: 11098

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEQNLTSEALTVTTVTSQDQITQKPLRDSVKASLKNYLAQLNGQEVSELYELVLAEVEQ
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PLLDTIMQYTRGNQTRAATMMGINRGTLRKKLKKYGMN
HHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MFEQNLTSEALTVTTVTSQDQITQKPLRDSVKASLKNYLAQLNGQEVSELYELVLAEVEQ
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PLLDTIMQYTRGNQTRAATMMGINRGTLRKKLKKYGMN
HHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA