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The map label for this gene is aroQ [H]

Identifier: 218710859

GI number: 218710859

Start: 3102647

End: 3103144

Strand: Direct

Name: aroQ [H]

Synonym: VS_2943

Alternate gene names: 218710859

Gene position: 3102647-3103144 (Clockwise)

Preceding gene: 218710858

Following gene: 218710860

Centisome position: 94.04

GC content: 42.97

Gene sequence:

>498_bases
ATGGCAACATTCACGTTCGTAAACACGATAAAGGAAGATAGCCCCACAATGTCTACAAAGTTTCGCATTCTAGTTTTAAA
TGGACCAAACCTTAATCTGTTAGGCCTTAGAGAACCTGCACACTACGGTTCTCAAACACTTGACCAGATTATTAGCTCAT
TGACCGAGCAAGCGAAAACACACGATGTTGAGCTATCTCACTTACAGTCAAATCGTGAGTATGAGCTGATTGAAGCTATC
CATAGTGCTTATCAAAATGTTGATTTCATTATCATCAACCCAGCGGCCTTTACACATACCAGTGTGGCGTTGCGTGATGC
ACTACTTGGTGTTGCTATCCCATTTATTGAGGTTCACCTATCGAATGTTCACGCACGTGAACCATTCCGTCACCACTCTT
ACCTGTCTGATAAAGCAGAAGGTGTGATTTGTGGCTTAGGTGCCCAAGGTTATCAATTTGCTTTGACAGCTGCGCTCAAC
AAGCTCAACGCAAAGTAA

Upstream 100 bases:

>100_bases
CAGTAAATTGCTGCGATTTGCGCTGAATTAGCTATAATCTGGTTCTAATTTTTAAATTTGGGTTTTTCTTACTGGAAATT
ATCCCCAAATTTTCAATAAA

Downstream 100 bases:

>100_bases
ATAAAAACAACGAACTATTACTAACCTACTCAGTCAAAGAGTAAGTTCAATCAACAGATAAAGAGAAAGAAACAATGGAT
ATTCGCAAAATCAAGAAGCT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MATFTFVNTIKEDSPTMSTKFRILVLNGPNLNLLGLREPAHYGSQTLDQIISSLTEQAKTHDVELSHLQSNREYELIEAI
HSAYQNVDFIIINPAAFTHTSVALRDALLGVAIPFIEVHLSNVHAREPFRHHSYLSDKAEGVICGLGAQGYQFALTAALN
KLNAK

Sequences:

>Translated_165_residues
MATFTFVNTIKEDSPTMSTKFRILVLNGPNLNLLGLREPAHYGSQTLDQIISSLTEQAKTHDVELSHLQSNREYELIEAI
HSAYQNVDFIIINPAAFTHTSVALRDALLGVAIPFIEVHLSNVHAREPFRHHSYLSDKAEGVICGLGAQGYQFALTAALN
KLNAK
>Mature_164_residues
ATFTFVNTIKEDSPTMSTKFRILVLNGPNLNLLGLREPAHYGSQTLDQIISSLTEQAKTHDVELSHLQSNREYELIEAIH
SAYQNVDFIIINPAAFTHTSVALRDALLGVAIPFIEVHLSNVHAREPFRHHSYLSDKAEGVICGLGAQGYQFALTAALNK
LNAK

Specific function: Catalyzes a trans-dehydration via an enolate intermediate [H]

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001874
- InterPro:   IPR018509
- ProDom:   PD004527 [H]

Pfam domain/function: PF01220 DHquinase_II [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 18255; Mature: 18124

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFTFVNTIKEDSPTMSTKFRILVLNGPNLNLLGLREPAHYGSQTLDQIISSLTEQAKT
CCEEHEEHHHCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
HDVELSHLQSNREYELIEAIHSAYQNVDFIIINPAAFTHTSVALRDALLGVAIPFIEVHL
CCCHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHC
SNVHAREPFRHHSYLSDKAEGVICGLGAQGYQFALTAALNKLNAK
CCCCCCCCHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATFTFVNTIKEDSPTMSTKFRILVLNGPNLNLLGLREPAHYGSQTLDQIISSLTEQAKT
CEEHEEHHHCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
HDVELSHLQSNREYELIEAIHSAYQNVDFIIINPAAFTHTSVALRDALLGVAIPFIEVHL
CCCHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHC
SNVHAREPFRHHSYLSDKAEGVICGLGAQGYQFALTAALNKLNAK
CCCCCCCCHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]