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The map label for this gene is dipZ [H]

Identifier: 218710847

GI number: 218710847

Start: 3083771

End: 3085636

Strand: Direct

Name: dipZ [H]

Synonym: VS_2930

Alternate gene names: 218710847

Gene position: 3083771-3085636 (Clockwise)

Preceding gene: 218710846

Following gene: 218710848

Centisome position: 93.47

GC content: 48.87

Gene sequence:

>1866_bases
ATGCGACGACTTGCCACATTACTTTTTGTTTGTGTTTCCCTGTTCACCCAGCCTGCGTGGGCGCTTTTTGGAAACGACAA
CGCCGAGCCAAGCTTCGGAGGCAATAACAACGGTTTTGTCCCTGTAGACCAAGCTTTCCCTTTCAATTACTACCAGCAAG
ACGGCAAGGTCCTTCTCGACTGGCAAGTAAAAGAGGGCTACTACCTCTATCAACATAGCCTCTCGTTCACTGGCCAAAAT
CTCACTATCGGCAATGTTGAAATGGAAAATGGCCAACCACACCAAGATGAATTCTTCGGTGAGGTGAGCATCTATACTCA
GCCATTATTCGTGCAAGTTCCTCTACAGAGTTACCAAGTTGGCTCACAGCTGATCGTTAAGTATCAAGGCTGTGCAGATG
CTGGTTTCTGTTACCCACCAGAGATCCGAGTAATCGACATTGAACCGTTTACTGCGACGAGTTCTGGGGATATGAAAAGC
AGTGATGAGCAAAACAGTGGTGCTTTACAAGGTTCTTCTGATGCAGCTGGTGAAGCTGACAATTCAGTACAAGCCTCTTC
TCCTAGCACTGACGCAGCAAGCAATACCACTCAACAAGCCAATGCTCCCGTATCAAAAGAAGCTGGCTTAGCCGATAAGC
TCGGTGACAGTTGGTGGACGCCACTATTATTCTTAGCTCTCGGTGTTGGCTTAGCCTTTACGCCGTGTGTTCTGCCTATG
TACCCAATCCTAACCGGTATCGTATTAGGCGGCGGCAAGCTCAGCCAAGGTCGCGCGCTGATGCTGTCCTTCATCTACGT
GCAAGGCATGGCGCTGACCTACACCTTATTGGGTTTAGTGGTTGCTTCAGCAGGCATGCAGTTCCAAGCTGCGATGCAGC
ATCCTTACGTATTAATCGCGCTGAGTGTTCTGTTCGTGACGTTGGCGATGTCGATGTTCGGCGTTTATAACCTACAACTG
CCAAGCAGCATCCAAACTTGGCTTAACAACCAAAGCAACAAGCAACAAGGTGGCAATACCTTAGGCGTGTTCGCGATGGG
TGCTATCTCTGGCTTGGTGTGTTCACCTTGTACCACAGCGCCACTGTCAGGCGCGTTATTGTATGTGGCTCAAAGTGGCG
ACCTATTAACCGGAGCGATCGCTCTGTATGCGTTAGCTATGGGTATGGGTATTCCGCTGATTTTGGTTGCGGTGTTTGGT
AATAAACTACTACCAAAAGCAGGCAGCTGGATGGACAAGGTGAAGATCGTATTCGGCTTTATCTTGCTGGCAGCGCCTAT
CTTCCTGCTAGAGCGAATTATTCCTGAATTGTGGGCAACGGTACTTTGGTCTGGTCTTGGGTTCATCGCCTTTGGTTGGC
TTTACCACAGCAAGAATGCACTGCCATTCGGTGGTTGGAAACAGAGCGCTGTAGGTATCATCGCGATGCTTGGCCTGTTC
GCATCAGCTCAACCTGCACTCAATTACTGGTTCGCAGAAAAGAGCGTTGTGGTTGAGCAACAAATCCAATTTGCCCGCGT
CAACACGGTTGAAGAGTTAGAAATCCAGCTCATCGAAGCCAAGAAACTCGGCAAGCCAGTGATGCTCGATTTCTACGCCG
ATTGGTGTGTGGCATGTAAAGAGTTTGAGAAGTACACCTTCCACCAAGCTGATGTTGAGAACAAGCTTTCTGATTTCGTC
CTGCTTCAGGCTGACGTAACGAGAAACATGCCTCAAGACATTGAACTGCTTAAACAATTGCAGGTACTCGGCTTACCAAC
CATTGAGTTCTGGGACGGCAAGGGTAACCATGTTCCAAATGCTCGTGTGACGGGCTTTATGCCTGCCGATGTATTCTTAA
AACACATGCAAGACCACCAGCTATAG

Upstream 100 bases:

>100_bases
CCGCCTTAGGGGATATTTGTCTACCGATGAAACTAATCACAAACTATTACGGTCTGATTGAGTTAAGATACCTTCAACTC
CATTTTGATGACTAAATAGT

Downstream 100 bases:

>100_bases
CGACGACATTCGTCTAAATACAAGCACTAACGAAAGCCGCACCGCCCCTCCGTAACGAGATGGCTGTGCGGCTTTTTTGT
TATTCAGAGTAACGCTTTCT

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MRRLATLLFVCVSLFTQPAWALFGNDNAEPSFGGNNNGFVPVDQAFPFNYYQQDGKVLLDWQVKEGYYLYQHSLSFTGQN
LTIGNVEMENGQPHQDEFFGEVSIYTQPLFVQVPLQSYQVGSQLIVKYQGCADAGFCYPPEIRVIDIEPFTATSSGDMKS
SDEQNSGALQGSSDAAGEADNSVQASSPSTDAASNTTQQANAPVSKEAGLADKLGDSWWTPLLFLALGVGLAFTPCVLPM
YPILTGIVLGGGKLSQGRALMLSFIYVQGMALTYTLLGLVVASAGMQFQAAMQHPYVLIALSVLFVTLAMSMFGVYNLQL
PSSIQTWLNNQSNKQQGGNTLGVFAMGAISGLVCSPCTTAPLSGALLYVAQSGDLLTGAIALYALAMGMGIPLILVAVFG
NKLLPKAGSWMDKVKIVFGFILLAAPIFLLERIIPELWATVLWSGLGFIAFGWLYHSKNALPFGGWKQSAVGIIAMLGLF
ASAQPALNYWFAEKSVVVEQQIQFARVNTVEELEIQLIEAKKLGKPVMLDFYADWCVACKEFEKYTFHQADVENKLSDFV
LLQADVTRNMPQDIELLKQLQVLGLPTIEFWDGKGNHVPNARVTGFMPADVFLKHMQDHQL

Sequences:

>Translated_621_residues
MRRLATLLFVCVSLFTQPAWALFGNDNAEPSFGGNNNGFVPVDQAFPFNYYQQDGKVLLDWQVKEGYYLYQHSLSFTGQN
LTIGNVEMENGQPHQDEFFGEVSIYTQPLFVQVPLQSYQVGSQLIVKYQGCADAGFCYPPEIRVIDIEPFTATSSGDMKS
SDEQNSGALQGSSDAAGEADNSVQASSPSTDAASNTTQQANAPVSKEAGLADKLGDSWWTPLLFLALGVGLAFTPCVLPM
YPILTGIVLGGGKLSQGRALMLSFIYVQGMALTYTLLGLVVASAGMQFQAAMQHPYVLIALSVLFVTLAMSMFGVYNLQL
PSSIQTWLNNQSNKQQGGNTLGVFAMGAISGLVCSPCTTAPLSGALLYVAQSGDLLTGAIALYALAMGMGIPLILVAVFG
NKLLPKAGSWMDKVKIVFGFILLAAPIFLLERIIPELWATVLWSGLGFIAFGWLYHSKNALPFGGWKQSAVGIIAMLGLF
ASAQPALNYWFAEKSVVVEQQIQFARVNTVEELEIQLIEAKKLGKPVMLDFYADWCVACKEFEKYTFHQADVENKLSDFV
LLQADVTRNMPQDIELLKQLQVLGLPTIEFWDGKGNHVPNARVTGFMPADVFLKHMQDHQL
>Mature_621_residues
MRRLATLLFVCVSLFTQPAWALFGNDNAEPSFGGNNNGFVPVDQAFPFNYYQQDGKVLLDWQVKEGYYLYQHSLSFTGQN
LTIGNVEMENGQPHQDEFFGEVSIYTQPLFVQVPLQSYQVGSQLIVKYQGCADAGFCYPPEIRVIDIEPFTATSSGDMKS
SDEQNSGALQGSSDAAGEADNSVQASSPSTDAASNTTQQANAPVSKEAGLADKLGDSWWTPLLFLALGVGLAFTPCVLPM
YPILTGIVLGGGKLSQGRALMLSFIYVQGMALTYTLLGLVVASAGMQFQAAMQHPYVLIALSVLFVTLAMSMFGVYNLQL
PSSIQTWLNNQSNKQQGGNTLGVFAMGAISGLVCSPCTTAPLSGALLYVAQSGDLLTGAIALYALAMGMGIPLILVAVFG
NKLLPKAGSWMDKVKIVFGFILLAAPIFLLERIIPELWATVLWSGLGFIAFGWLYHSKNALPFGGWKQSAVGIIAMLGLF
ASAQPALNYWFAEKSVVVEQQIQFARVNTVEELEIQLIEAKKLGKPVMLDFYADWCVACKEFEKYTFHQADVENKLSDFV
LLQADVTRNMPQDIELLKQLQVLGLPTIEFWDGKGNHVPNARVTGFMPADVFLKHMQDHQL

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=587, Percent_Identity=49.5741056218058, Blast_Score=554, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 67665; Mature: 67665

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLATLLFVCVSLFTQPAWALFGNDNAEPSFGGNNNGFVPVDQAFPFNYYQQDGKVLLD
CHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEECCCCCCCCCEECCCCEEEE
WQVKEGYYLYQHSLSFTGQNLTIGNVEMENGQPHQDEFFGEVSIYTQPLFVQVPLQSYQV
EEECCCEEEEEEEEEECCCCEEEEEEECCCCCCCHHHHCCEEEEEECCEEEEECHHHHHC
GSQLIVKYQGCADAGFCYPPEIRVIDIEPFTATSSGDMKSSDEQNSGALQGSSDAAGEAD
CCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSVQASSPSTDAASNTTQQANAPVSKEAGLADKLGDSWWTPLLFLALGVGLAFTPCVLPM
CCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
YPILTGIVLGGGKLSQGRALMLSFIYVQGMALTYTLLGLVVASAGMQFQAAMQHPYVLIA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHH
LSVLFVTLAMSMFGVYNLQLPSSIQTWLNNQSNKQQGGNTLGVFAMGAISGLVCSPCTTA
HHHHHHHHHHHHHCEEEECCCHHHHHHHCCCCCHHCCCCEEEHHHHHHHHHHHCCCCCCC
PLSGALLYVAQSGDLLTGAIALYALAMGMGIPLILVAVFGNKLLPKAGSWMDKVKIVFGF
CCCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ILLAAPIFLLERIIPELWATVLWSGLGFIAFGWLYHSKNALPFGGWKQSAVGIIAMLGLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
ASAQPALNYWFAEKSVVVEQQIQFARVNTVEELEIQLIEAKKLGKPVMLDFYADWCVACK
HCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHEEEHHHCCCCEEEHHHHHHHHHHH
EFEKYTFHQADVENKLSDFVLLQADVTRNMPQDIELLKQLQVLGLPTIEFWDGKGNHVPN
HHHHHHCCHHHHHHHHHHEEEEEEHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCC
ARVTGFMPADVFLKHMQDHQL
CCEEECCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRRLATLLFVCVSLFTQPAWALFGNDNAEPSFGGNNNGFVPVDQAFPFNYYQQDGKVLLD
CHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEECCCCCCCCCEECCCCEEEE
WQVKEGYYLYQHSLSFTGQNLTIGNVEMENGQPHQDEFFGEVSIYTQPLFVQVPLQSYQV
EEECCCEEEEEEEEEECCCCEEEEEEECCCCCCCHHHHCCEEEEEECCEEEEECHHHHHC
GSQLIVKYQGCADAGFCYPPEIRVIDIEPFTATSSGDMKSSDEQNSGALQGSSDAAGEAD
CCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSVQASSPSTDAASNTTQQANAPVSKEAGLADKLGDSWWTPLLFLALGVGLAFTPCVLPM
CCCCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
YPILTGIVLGGGKLSQGRALMLSFIYVQGMALTYTLLGLVVASAGMQFQAAMQHPYVLIA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHH
LSVLFVTLAMSMFGVYNLQLPSSIQTWLNNQSNKQQGGNTLGVFAMGAISGLVCSPCTTA
HHHHHHHHHHHHHCEEEECCCHHHHHHHCCCCCHHCCCCEEEHHHHHHHHHHHCCCCCCC
PLSGALLYVAQSGDLLTGAIALYALAMGMGIPLILVAVFGNKLLPKAGSWMDKVKIVFGF
CCCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ILLAAPIFLLERIIPELWATVLWSGLGFIAFGWLYHSKNALPFGGWKQSAVGIIAMLGLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
ASAQPALNYWFAEKSVVVEQQIQFARVNTVEELEIQLIEAKKLGKPVMLDFYADWCVACK
HCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHEEEHHHCCCCEEEHHHHHHHHHHH
EFEKYTFHQADVENKLSDFVLLQADVTRNMPQDIELLKQLQVLGLPTIEFWDGKGNHVPN
HHHHHHCCHHHHHHHHHHEEEEEEHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCC
ARVTGFMPADVFLKHMQDHQL
CCEEECCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]