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The map label for this gene is arcB [H]

Identifier: 218710843

GI number: 218710843

Start: 3079860

End: 3080870

Strand: Direct

Name: arcB [H]

Synonym: VS_2926

Alternate gene names: 218710843

Gene position: 3079860-3080870 (Clockwise)

Preceding gene: 218710842

Following gene: 218710844

Centisome position: 93.35

GC content: 46.59

Gene sequence:

>1011_bases
ATGGCTTTTAACCTACGCAATCGTAACTTCCTAAAACTACTAGATTTCACTCCACGCGAAATTCAACACTTGTTAGATCT
TTCTATGGAGCTAAAAAAAGCGAAGTACAACGGTTACGAACAGCCAACACTGACTGGCAAAAACATTGCGCTTATCTTTG
AAAAAACCTCAACTCGTACTCGCTGTGCATTCGAAGTAGCAGCATTCGACCAAGGTGCTCGAGTTTCTTACTTAGGCCCA
TCTGGCTCTCAAATTGGCCACAAAGAATCAATGAAAGACACCGCTCGCGTTCTAGGCCGTATGTACGATGGCATCGAATA
CCGCGGCTTTGGTCAAGAAATCGTTGAAGAGCTAGGCGCTTACGCTGGCGTTCCTGTGTGGAATGGCCTGACTGACGAAT
TCCACCCAACACAGATCCTAGCTGACTTCCTAACTATGACGGAATACGGCCGTGGCAAGCAATTGCATGAAATCAAGTTT
GCTTACCTAGGTGATGCTCGCAACAACATGGGCAACTCTCTGATGGTTGGTGCTGCTAAAATGGGCATGGACATTCGCCT
TGTTGCTCCAAAACAATTCTGGCCAGAAGAAGAGCTATTAGCTCAATGTCGTGAAATCGCAGAACACACTGGCGGCAAAA
TCACGCTAACAGAAGATGTTCAAGAAGGCGTGCAAGGTTGTGACTTCCTATATACCGACGTTTGGGTATCAATGGGCGAA
GCGAAAGAAGCATGGGCTGAGCGTATCAACCTAATGATGCCTTACCAAGTCAACATGGACATGATCAAAGCAACAGGCAA
CCCACATGTGAAATTCATGCACTGCCTACCTGCTTTCCACGGCGAAGATACAACTGTCGGCAAACAGCTTGCTGCTGAAT
ATCCGCAGCTTAAAGATGGCGTAGAAGTGACGGATGAAGTGGTTGAGTCTGAATACTCTATCGTGTTCGATGAAGCAGAA
AACCGCATGCACACCATCAAAGCAGTAATGGTTGCGACATTAGGCAGCTAA

Upstream 100 bases:

>100_bases
CAAACAAAACCGAACAACTTTAACTAAAAATTGAATCGCGCTTTCTTGAATTTTATTTCCCTGTAACAAGGAAGCGCCTA
AATCTAAGAAGGAATACATC

Downstream 100 bases:

>100_bases
TTACCTAAGAAACTAAACAGTTAAGACGTTAAAAATTAAGAAGCTAGGCACTCACTTGTTCGAAATACGTTGATAAGTTA
AGTGCAATGACAGGGAAATG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MAFNLRNRNFLKLLDFTPREIQHLLDLSMELKKAKYNGYEQPTLTGKNIALIFEKTSTRTRCAFEVAAFDQGARVSYLGP
SGSQIGHKESMKDTARVLGRMYDGIEYRGFGQEIVEELGAYAGVPVWNGLTDEFHPTQILADFLTMTEYGRGKQLHEIKF
AYLGDARNNMGNSLMVGAAKMGMDIRLVAPKQFWPEEELLAQCREIAEHTGGKITLTEDVQEGVQGCDFLYTDVWVSMGE
AKEAWAERINLMMPYQVNMDMIKATGNPHVKFMHCLPAFHGEDTTVGKQLAAEYPQLKDGVEVTDEVVESEYSIVFDEAE
NRMHTIKAVMVATLGS

Sequences:

>Translated_336_residues
MAFNLRNRNFLKLLDFTPREIQHLLDLSMELKKAKYNGYEQPTLTGKNIALIFEKTSTRTRCAFEVAAFDQGARVSYLGP
SGSQIGHKESMKDTARVLGRMYDGIEYRGFGQEIVEELGAYAGVPVWNGLTDEFHPTQILADFLTMTEYGRGKQLHEIKF
AYLGDARNNMGNSLMVGAAKMGMDIRLVAPKQFWPEEELLAQCREIAEHTGGKITLTEDVQEGVQGCDFLYTDVWVSMGE
AKEAWAERINLMMPYQVNMDMIKATGNPHVKFMHCLPAFHGEDTTVGKQLAAEYPQLKDGVEVTDEVVESEYSIVFDEAE
NRMHTIKAVMVATLGS
>Mature_335_residues
AFNLRNRNFLKLLDFTPREIQHLLDLSMELKKAKYNGYEQPTLTGKNIALIFEKTSTRTRCAFEVAAFDQGARVSYLGPS
GSQIGHKESMKDTARVLGRMYDGIEYRGFGQEIVEELGAYAGVPVWNGLTDEFHPTQILADFLTMTEYGRGKQLHEIKFA
YLGDARNNMGNSLMVGAAKMGMDIRLVAPKQFWPEEELLAQCREIAEHTGGKITLTEDVQEGVQGCDFLYTDVWVSMGEA
KEAWAERINLMMPYQVNMDMIKATGNPHVKFMHCLPAFHGEDTTVGKQLAAEYPQLKDGVEVTDEVVESEYSIVFDEAEN
RMHTIKAVMVATLGS

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=331, Percent_Identity=37.4622356495468, Blast_Score=201, Evalue=8e-52,
Organism=Escherichia coli, GI1786469, Length=332, Percent_Identity=69.578313253012, Blast_Score=483, Evalue=1e-138,
Organism=Escherichia coli, GI1790703, Length=328, Percent_Identity=69.2073170731707, Blast_Score=480, Evalue=1e-137,
Organism=Escherichia coli, GI48994908, Length=375, Percent_Identity=22.9333333333333, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322373, Length=338, Percent_Identity=32.5443786982249, Blast_Score=159, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37775; Mature: 37643

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFNLRNRNFLKLLDFTPREIQHLLDLSMELKKAKYNGYEQPTLTGKNIALIFEKTSTRT
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCC
RCAFEVAAFDQGARVSYLGPSGSQIGHKESMKDTARVLGRMYDGIEYRGFGQEIVEELGA
CEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YAGVPVWNGLTDEFHPTQILADFLTMTEYGRGKQLHEIKFAYLGDARNNMGNSLMVGAAK
HCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCCCCCCCEEEEEHHH
MGMDIRLVAPKQFWPEEELLAQCREIAEHTGGKITLTEDVQEGVQGCDFLYTDVWVSMGE
HCCEEEEECCHHCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCH
AKEAWAERINLMMPYQVNMDMIKATGNPHVKFMHCLPAFHGEDTTVGKQLAAEYPQLKDG
HHHHHHHHHCEECCEEECCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCC
VEVTDEVVESEYSIVFDEAENRMHTIKAVMVATLGS
HHHHHHHHHCHHEEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AFNLRNRNFLKLLDFTPREIQHLLDLSMELKKAKYNGYEQPTLTGKNIALIFEKTSTRT
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCC
RCAFEVAAFDQGARVSYLGPSGSQIGHKESMKDTARVLGRMYDGIEYRGFGQEIVEELGA
CEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YAGVPVWNGLTDEFHPTQILADFLTMTEYGRGKQLHEIKFAYLGDARNNMGNSLMVGAAK
HCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCCCCCCCEEEEEHHH
MGMDIRLVAPKQFWPEEELLAQCREIAEHTGGKITLTEDVQEGVQGCDFLYTDVWVSMGE
HCCEEEEECCHHCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCH
AKEAWAERINLMMPYQVNMDMIKATGNPHVKFMHCLPAFHGEDTTVGKQLAAEYPQLKDG
HHHHHHHHHCEECCEEECCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCC
VEVTDEVVESEYSIVFDEAENRMHTIKAVMVATLGS
HHHHHHHHHCHHEEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA