Click here to switch to the map view.

The map label for this gene is aroB

Identifier: 218710788

GI number: 218710788

Start: 3019067

End: 3020155

Strand: Reverse

Name: aroB

Synonym: VS_2871

Alternate gene names: 218710788

Gene position: 3020155-3019067 (Counterclockwise)

Preceding gene: 218710789

Following gene: 218710787

Centisome position: 91.54

GC content: 44.44

Gene sequence:

>1089_bases
ATGGAACGGATTACGGTCAATCTAGCTGAGCGTAGCTACCCTATCTCTATTGGCGCCGGGTTATTTGAAGACCCGGCGTA
CCTTTCTTTTTTATCAGGTAAGCAGAAAGTTGTTGTTATCAGTAATGTGACAGTAGCGCCTCTTTATGCTGATAAAATTT
TATCGCTATTGGATCAAGTCGGCTGTCAGACATCTCTTCTCGAGCTGCCAGACGGTGAACAGTACAAAAACCTTGAAACG
TTCAATTCAGTGATGAGCTACATGCTTGAAGGAAATTACAGCCGCGATGTGGTGGTGATTGCTTTGGGTGGTGGTGTTAT
CGGTGATTTGGTCGGTTTTGCTGCCTCTTGCTACCAGCGCGGTATTGATTTCATTCAAATCCCGACGACCCTTCTTTCTC
AAGTGGACTCCTCTGTAGGTGGTAAAACCGCAGTGAACCATCCCCTTGGCAAGAATATGATCGGCGCTTTTTACCAACCA
AAATCTGTCATCATCGATACTAACTGCCTATCAACGCTTCCAGAGCGTGAGTTTGCAGCGGGCATGGCTGAGGTGATCAA
ATACGGCATCATTTACGATGAAGCCTTTTTTGGCTGGTTGGAACAGAATCTAGAGAAACTGTATCAACTTGATGAAGACG
CACTGATTACCGCGATTGCTCGTTGTTGTGCAATTAAGGCTGAAGTGGTTGCTATCGATGAAAAAGAGTCAGGAATCAGA
GCGTTATTGAACCTAGGTCATACATTTGGTCATGCGATTGAAGCAGAACTAGGCTATGGTAATTGGCTACATGGTGAAGC
TGTGTCGTCAGGCACTGTAATGGCAGCAAAAACCGCCCAATTACAGGGACTGATTTCTCAGCAGCAACTTGAGCGAATTA
TTTCTATACTCAAGAATGCGAAACTACCAATCCATACGCCAGAAAGCATGTCTTTTGAAGACTTTATGAAGCACATGATG
CGCGATAAAAAAGTGCTGTCTGGTCAGTTGCGTCTGGTATTACCAACAAGTATTGGTACTGCTGAAGTGGTTGCTGATGT
ACCTCAAGACATCATTAAACAAGCGATTGATTTCTGCCGTACTCTTTAA

Upstream 100 bases:

>100_bases
CTACACAGTTCGTACTGACGACCAAAGTGCAAAAGTGGTAGCCAACCAGATCGTAAAAATGCTAGAAGAACGTTAAGTTC
ATTTTTCGGAGAGCAAACCC

Downstream 100 bases:

>100_bases
ATTCGGTTATGAGGTTGCCTAGCTAAACTCTAGGCAACTCAAGCGCTTTACAGATCGAACTTATCAGTAGGGATCCCCAA
TGAGTTTGGCTCATGATTTA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MERITVNLAERSYPISIGAGLFEDPAYLSFLSGKQKVVVISNVTVAPLYADKILSLLDQVGCQTSLLELPDGEQYKNLET
FNSVMSYMLEGNYSRDVVVIALGGGVIGDLVGFAASCYQRGIDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
KSVIIDTNCLSTLPEREFAAGMAEVIKYGIIYDEAFFGWLEQNLEKLYQLDEDALITAIARCCAIKAEVVAIDEKESGIR
ALLNLGHTFGHAIEAELGYGNWLHGEAVSSGTVMAAKTAQLQGLISQQQLERIISILKNAKLPIHTPESMSFEDFMKHMM
RDKKVLSGQLRLVLPTSIGTAEVVADVPQDIIKQAIDFCRTL

Sequences:

>Translated_362_residues
MERITVNLAERSYPISIGAGLFEDPAYLSFLSGKQKVVVISNVTVAPLYADKILSLLDQVGCQTSLLELPDGEQYKNLET
FNSVMSYMLEGNYSRDVVVIALGGGVIGDLVGFAASCYQRGIDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
KSVIIDTNCLSTLPEREFAAGMAEVIKYGIIYDEAFFGWLEQNLEKLYQLDEDALITAIARCCAIKAEVVAIDEKESGIR
ALLNLGHTFGHAIEAELGYGNWLHGEAVSSGTVMAAKTAQLQGLISQQQLERIISILKNAKLPIHTPESMSFEDFMKHMM
RDKKVLSGQLRLVLPTSIGTAEVVADVPQDIIKQAIDFCRTL
>Mature_362_residues
MERITVNLAERSYPISIGAGLFEDPAYLSFLSGKQKVVVISNVTVAPLYADKILSLLDQVGCQTSLLELPDGEQYKNLET
FNSVMSYMLEGNYSRDVVVIALGGGVIGDLVGFAASCYQRGIDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
KSVIIDTNCLSTLPEREFAAGMAEVIKYGIIYDEAFFGWLEQNLEKLYQLDEDALITAIARCCAIKAEVVAIDEKESGIR
ALLNLGHTFGHAIEAELGYGNWLHGEAVSSGTVMAAKTAQLQGLISQQQLERIISILKNAKLPIHTPESMSFEDFMKHMM
RDKKVLSGQLRLVLPTSIGTAEVVADVPQDIIKQAIDFCRTL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=361, Percent_Identity=59.0027700831025, Blast_Score=449, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6320332, Length=351, Percent_Identity=37.037037037037, Blast_Score=204, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_VIBSL (B7VLJ6)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002418409.1
- GeneID:   7162356
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2871
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- ProtClustDB:   PRK00002
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39517; Mature: 39517

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERITVNLAERSYPISIGAGLFEDPAYLSFLSGKQKVVVISNVTVAPLYADKILSLLDQV
CCEEEEEECCCCCCEEECCCCCCCCHHHHHHCCCCEEEEEECCEECHHHHHHHHHHHHHH
GCQTSLLELPDGEQYKNLETFNSVMSYMLEGNYSRDVVVIALGGGVIGDLVGFAASCYQR
CCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHC
GIDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKSVIIDTNCLSTLPEREFAA
CCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEEECHHHHHCCCHHHHH
GMAEVIKYGIIYDEAFFGWLEQNLEKLYQLDEDALITAIARCCAIKAEVVAIDEKESGIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCHHHHH
ALLNLGHTFGHAIEAELGYGNWLHGEAVSSGTVMAAKTAQLQGLISQQQLERIISILKNA
HHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCC
KLPIHTPESMSFEDFMKHMMRDKKVLSGQLRLVLPTSIGTAEVVADVPQDIIKQAIDFCR
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
TL
CC
>Mature Secondary Structure
MERITVNLAERSYPISIGAGLFEDPAYLSFLSGKQKVVVISNVTVAPLYADKILSLLDQV
CCEEEEEECCCCCCEEECCCCCCCCHHHHHHCCCCEEEEEECCEECHHHHHHHHHHHHHH
GCQTSLLELPDGEQYKNLETFNSVMSYMLEGNYSRDVVVIALGGGVIGDLVGFAASCYQR
CCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHC
GIDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKSVIIDTNCLSTLPEREFAA
CCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEEECHHHHHCCCHHHHH
GMAEVIKYGIIYDEAFFGWLEQNLEKLYQLDEDALITAIARCCAIKAEVVAIDEKESGIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCHHHHH
ALLNLGHTFGHAIEAELGYGNWLHGEAVSSGTVMAAKTAQLQGLISQQQLERIISILKNA
HHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCC
KLPIHTPESMSFEDFMKHMMRDKKVLSGQLRLVLPTSIGTAEVVADVPQDIIKQAIDFCR
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
TL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA