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The map label for this gene is aroK [H]

Identifier: 218710789

GI number: 218710789

Start: 3020180

End: 3020698

Strand: Reverse

Name: aroK [H]

Synonym: VS_2872

Alternate gene names: 218710789

Gene position: 3020698-3020180 (Counterclockwise)

Preceding gene: 218710790

Following gene: 218710788

Centisome position: 91.56

GC content: 46.63

Gene sequence:

>519_bases
ATGGCTGAGAAACGCAATATTTTTCTTGTTGGCCCAATGGGCGCCGGCAAAAGTACAATTGGTAGACACCTAGCTTCCCA
ACTTCATATGGAGTTTCTAGACTCTGACACTGTGATCGAAGAGCGCACTGGCGCAGACATCGCATGGGTTTTTGATGTTG
AGGGCGAAGATGGTTTCCGTAAGCGCGAAGAATCTGTAATCAACGATCTGACAGAAGAACAAGGTATTGTTCTTGCGACA
GGTGGTGGTTCAGTGCTGAGCAAAGAAAACCGTAACCGTCTATCTGCACGAGGCATTGTTGTATACCTAGAGACAACAAT
TGAAAAGCAACTTGCTCGCACTAACCGCGACAAGAAACGCCCTCTACTTCAAACAGACAACCCGCGTGATGTGCTAGAAG
ATCTAGCTGTATCTCGCAACGCACTATACGAAGAAGTGGCGGACTACACAGTTCGTACTGACGACCAAAGTGCAAAAGTG
GTAGCCAACCAGATCGTAAAAATGCTAGAAGAACGTTAA

Upstream 100 bases:

>100_bases
TGTGAGGAATCGGTGCCACGGGCCTTTTAATTTCAGTACTTGTACTGACCTACCTTGTGGCGATGTCATTGAATTAACGT
TGTAAATTACTGCTAAAAAC

Downstream 100 bases:

>100_bases
GTTCATTTTTCGGAGAGCAAACCCATGGAACGGATTACGGTCAATCTAGCTGAGCGTAGCTACCCTATCTCTATTGGCGC
CGGGTTATTTGAAGACCCGG

Product: shikimate kinase I

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MAEKRNIFLVGPMGAGKSTIGRHLASQLHMEFLDSDTVIEERTGADIAWVFDVEGEDGFRKREESVINDLTEEQGIVLAT
GGGSVLSKENRNRLSARGIVVYLETTIEKQLARTNRDKKRPLLQTDNPRDVLEDLAVSRNALYEEVADYTVRTDDQSAKV
VANQIVKMLEER

Sequences:

>Translated_172_residues
MAEKRNIFLVGPMGAGKSTIGRHLASQLHMEFLDSDTVIEERTGADIAWVFDVEGEDGFRKREESVINDLTEEQGIVLAT
GGGSVLSKENRNRLSARGIVVYLETTIEKQLARTNRDKKRPLLQTDNPRDVLEDLAVSRNALYEEVADYTVRTDDQSAKV
VANQIVKMLEER
>Mature_171_residues
AEKRNIFLVGPMGAGKSTIGRHLASQLHMEFLDSDTVIEERTGADIAWVFDVEGEDGFRKREESVINDLTEEQGIVLATG
GGSVLSKENRNRLSARGIVVYLETTIEKQLARTNRDKKRPLLQTDNPRDVLEDLAVSRNALYEEVADYTVRTDDQSAKVV
ANQIVKMLEER

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=171, Percent_Identity=79.5321637426901, Blast_Score=276, Evalue=8e-76,
Organism=Escherichia coli, GI1786587, Length=159, Percent_Identity=31.4465408805031, Blast_Score=88, Evalue=4e-19,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19291; Mature: 19160

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKRNIFLVGPMGAGKSTIGRHLASQLHMEFLDSDTVIEERTGADIAWVFDVEGEDGFR
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEECCCCCHH
KREESVINDLTEEQGIVLATGGGSVLSKENRNRLSARGIVVYLETTIEKQLARTNRDKKR
HHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCHHCC
PLLQTDNPRDVLEDLAVSRNALYEEVADYTVRTDDQSAKVVANQIVKMLEER
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEKRNIFLVGPMGAGKSTIGRHLASQLHMEFLDSDTVIEERTGADIAWVFDVEGEDGFR
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEEECCCCCHH
KREESVINDLTEEQGIVLATGGGSVLSKENRNRLSARGIVVYLETTIEKQLARTNRDKKR
HHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCHHCC
PLLQTDNPRDVLEDLAVSRNALYEEVADYTVRTDDQSAKVVANQIVKMLEER
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA