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The map label for this gene is rpe [H]

Identifier: 218710785

GI number: 218710785

Start: 3015677

End: 3016432

Strand: Reverse

Name: rpe [H]

Synonym: VS_2868

Alternate gene names: 218710785

Gene position: 3016432-3015677 (Counterclockwise)

Preceding gene: 218710786

Following gene: 218710784

Centisome position: 91.43

GC content: 46.03

Gene sequence:

>756_bases
TTGGGATTGAGTCTTGTACTTGTGTATGAGAGGTCACAAGGCGGTGATATTCGCAATTTACTCACTCTTAAGAGGTTTGG
TATGAAAGATTTTCTAATCGCTCCATCGATTTTGTCTGCAGATTTTGCTCGTCTTGGTGAAGACGTCGAAAAAGTACTCG
CAGCCGGTGCCGACGTTGTGCACTTCGATGTGATGGATAACCACTACGTACCTAACCTGACTTTTGGTGCACCGATCTGT
AAAGCATTGCGCGACTACGGCATCACAGCTCCTATCGATGTTCACCTAATGGTTAAGCCAGTAGACAGCATCGTACCTGA
GTTTGCCAAAGCTGGCGCATCAATGATTACCTTCCACGTTGAAGCGTCTGAGCACGTTGATCGCACTCTACAGTTAATCA
AAGAACACGGCTGTAAAGCGGGTGTCGTACTTAACCCAGCAACGCCACTTTCTTGCCTTGATTACATCCTAGACAAAGTC
GACATGATTCTACTGATGTCAGTGAACCCTGGCTTTGGCGGTCAATCTTTCATTCCTCACACACTTGATAAGCTGCGCGC
AGTTCGTAAACTTATTGACGAATCAGGCCGTGATATCCGTCTTGAGATTGATGGTGGCGTGAAGGTTGATAACATCCGTG
AAATTGCAGAAGCGGGCGCAGATATGTTCGTTGCCGGTTCAGCGATCTTCAATCAACCAAATTACAAAGAAGTGATTGAT
GAGATGCGTGCAGAGCTTGCAAAAGTTAACGCATAA

Upstream 100 bases:

>100_bases
ACTCATTAAATTGAGTGACCCACGGGTACTTTCTTAAACTAATCTTTCGAACTGCTAGGATCTGCTTAGGTGCTTAGGTA
GAATTGCACACCAAATAGTC

Downstream 100 bases:

>100_bases
TCGTAAAACTACAGATAGATTGAATATTAAGGGGCTCATTGGCCCCTTTTTTACGTCTTGGAGCTCAACTCATAAGACGG
ACATAATAAATAGGAAAGTA

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MGLSLVLVYERSQGGDIRNLLTLKRFGMKDFLIAPSILSADFARLGEDVEKVLAAGADVVHFDVMDNHYVPNLTFGAPIC
KALRDYGITAPIDVHLMVKPVDSIVPEFAKAGASMITFHVEASEHVDRTLQLIKEHGCKAGVVLNPATPLSCLDYILDKV
DMILLMSVNPGFGGQSFIPHTLDKLRAVRKLIDESGRDIRLEIDGGVKVDNIREIAEAGADMFVAGSAIFNQPNYKEVID
EMRAELAKVNA

Sequences:

>Translated_251_residues
MGLSLVLVYERSQGGDIRNLLTLKRFGMKDFLIAPSILSADFARLGEDVEKVLAAGADVVHFDVMDNHYVPNLTFGAPIC
KALRDYGITAPIDVHLMVKPVDSIVPEFAKAGASMITFHVEASEHVDRTLQLIKEHGCKAGVVLNPATPLSCLDYILDKV
DMILLMSVNPGFGGQSFIPHTLDKLRAVRKLIDESGRDIRLEIDGGVKVDNIREIAEAGADMFVAGSAIFNQPNYKEVID
EMRAELAKVNA
>Mature_250_residues
GLSLVLVYERSQGGDIRNLLTLKRFGMKDFLIAPSILSADFARLGEDVEKVLAAGADVVHFDVMDNHYVPNLTFGAPICK
ALRDYGITAPIDVHLMVKPVDSIVPEFAKAGASMITFHVEASEHVDRTLQLIKEHGCKAGVVLNPATPLSCLDYILDKVD
MILLMSVNPGFGGQSFIPHTLDKLRAVRKLIDESGRDIRLEIDGGVKVDNIREIAEAGADMFVAGSAIFNQPNYKEVIDE
MRAELAKVNA

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=212, Percent_Identity=40.5660377358491, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI219879828, Length=212, Percent_Identity=39.622641509434, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI24307923, Length=168, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1789788, Length=223, Percent_Identity=82.5112107623318, Blast_Score=378, Evalue=1e-106,
Organism=Escherichia coli, GI1790523, Length=211, Percent_Identity=36.9668246445498, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790754, Length=211, Percent_Identity=26.5402843601896, Blast_Score=90, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17552948, Length=227, Percent_Identity=38.7665198237885, Blast_Score=156, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6322341, Length=229, Percent_Identity=38.8646288209607, Blast_Score=163, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24586301, Length=211, Percent_Identity=40.7582938388626, Blast_Score=166, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 27418; Mature: 27287

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSLVLVYERSQGGDIRNLLTLKRFGMKDFLIAPSILSADFARLGEDVEKVLAAGADVV
CCCEEEEEEECCCCCCHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEE
HFDVMDNHYVPNLTFGAPICKALRDYGITAPIDVHLMVKPVDSIVPEFAKAGASMITFHV
EEEECCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHCCCEEEEEEE
EASEHVDRTLQLIKEHGCKAGVVLNPATPLSCLDYILDKVDMILLMSVNPGFGGQSFIPH
CCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHH
TLDKLRAVRKLIDESGRDIRLEIDGGVKVDNIREIAEAGADMFVAGSAIFNQPNYKEVID
HHHHHHHHHHHHHCCCCEEEEEECCCEEHHHHHHHHHCCCCEEEECHHHHCCCCHHHHHH
EMRAELAKVNA
HHHHHHHHCCC
>Mature Secondary Structure 
GLSLVLVYERSQGGDIRNLLTLKRFGMKDFLIAPSILSADFARLGEDVEKVLAAGADVV
CCEEEEEEECCCCCCHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEE
HFDVMDNHYVPNLTFGAPICKALRDYGITAPIDVHLMVKPVDSIVPEFAKAGASMITFHV
EEEECCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHCCCEEEEEEE
EASEHVDRTLQLIKEHGCKAGVVLNPATPLSCLDYILDKVDMILLMSVNPGFGGQSFIPH
CCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHH
TLDKLRAVRKLIDESGRDIRLEIDGGVKVDNIREIAEAGADMFVAGSAIFNQPNYKEVID
HHHHHHHHHHHHHCCCCEEEEEECCCEEHHHHHHHHHCCCCEEEECHHHHCCCCHHHHHH
EMRAELAKVNA
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]