Click here to switch to the map view.

The map label for this gene is pepA [H]

Identifier: 218710649

GI number: 218710649

Start: 2897503

End: 2898162

Strand: Direct

Name: pepA [H]

Synonym: VS_2729

Alternate gene names: 218710649

Gene position: 2897503-2898162 (Clockwise)

Preceding gene: 218710646

Following gene: 218710650

Centisome position: 87.82

GC content: 46.52

Gene sequence:

>660_bases
ATGGAGTTCAGTGTAAAAAGTGGCAGCCCAGAGAAACAGCGCAGCGCATGTATCGTTGTCGGTGTATTCGAACCGCGCCG
CCTTTCTCCAGTAGCCGAGCAGTTAGATAAGATTAGCGATGGCTATATTAGTTCACTGCTTCGTCGCGGTGATCTAGAGG
GTAAACCTGGCCAGATGCTACTACTGCATCAAGTACCTGGTGTACTTTCAGAACGTGTTCTGCTTGTAGGCTGCGGTAAA
GAACGTGAGCTAGGCGAGCGTCAATATAAAGAAATTATCCAAAAAACCATCAGCACACTAAACGAAACGGGTTCTATGGA
AGCAGTATGTTTCCTGACTGAACTGCACGTTAAAGGTCGTGATACTTACTGGAAAGTTCGCCAAGCAGTAGAAGCGACTA
AAGATGGCCTTTACACTTTTGATCAATTCAAGAGTAATAAACCAGAGACTCGTCGTCCACTACGTAAACTGGTATTCAAC
GTACCAACTCGTCGTGAATTGAGCCTTGGTGAGAAAGCTATCTCTCACGGTCTTGCGATTGCTTCAGGTGTGAAAGCGTC
TAAAGATCTAGGCAACATGCCACCTAACATCGCAAATCCTGCTTACCTTGCTTCTCAAGCTCGTAAGCTCGTCGCTTGGC
CGATGATTACGAGACAGTGA

Upstream 100 bases:

>100_bases
TAACGTTCTTCTTTAAGGTCAGTTCCATTATAGGATCCAACAAGTAAGAACCCATTATCCAACATTTAGTTCGATTTGTC
TTCAGGATGTAGGAGTACGC

Downstream 100 bases:

>100_bases
AAACTAAGATCATTGGCGAAGAAGAGATGGAAAAGCTGGGTATGACTTCATACTTAGCGGTAGGCCGTGGTTCTAAGAAC
GAATCTATGATGTCTATCAT

Product: hypothetical protein

Products: NA

Alternate protein names: Leucine aminopeptidase; LAP; Leucyl aminopeptidase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPVAEQLDKISDGYISSLLRRGDLEGKPGQMLLLHQVPGVLSERVLLVGCGK
ERELGERQYKEIIQKTISTLNETGSMEAVCFLTELHVKGRDTYWKVRQAVEATKDGLYTFDQFKSNKPETRRPLRKLVFN
VPTRRELSLGEKAISHGLAIASGVKASKDLGNMPPNIANPAYLASQARKLVAWPMITRQ

Sequences:

>Translated_219_residues
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPVAEQLDKISDGYISSLLRRGDLEGKPGQMLLLHQVPGVLSERVLLVGCGK
ERELGERQYKEIIQKTISTLNETGSMEAVCFLTELHVKGRDTYWKVRQAVEATKDGLYTFDQFKSNKPETRRPLRKLVFN
VPTRRELSLGEKAISHGLAIASGVKASKDLGNMPPNIANPAYLASQARKLVAWPMITRQ
>Mature_219_residues
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPVAEQLDKISDGYISSLLRRGDLEGKPGQMLLLHQVPGVLSERVLLVGCGK
ERELGERQYKEIIQKTISTLNETGSMEAVCFLTELHVKGRDTYWKVRQAVEATKDGLYTFDQFKSNKPETRRPLRKLVFN
VPTRRELSLGEKAISHGLAIASGVKASKDLGNMPPNIANPAYLASQARKLVAWPMITRQ

Specific function: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides [H]

COG id: COG0260

COG function: function code E; Leucyl aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M17 family [H]

Homologues:

Organism=Escherichia coli, GI1790710, Length=210, Percent_Identity=83.3333333333333, Blast_Score=357, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011356
- InterPro:   IPR000819
- InterPro:   IPR023042
- InterPro:   IPR008283 [H]

Pfam domain/function: PF00883 Peptidase_M17; PF02789 Peptidase_M17_N [H]

EC number: =3.4.11.1; =3.4.11.10 [H]

Molecular weight: Translated: 24422; Mature: 24422

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPVAEQLDKISDGYISSLLRRGDLEGKPGQML
CCCCCCCCCCHHHCCEEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEE
LLHQVPGVLSERVLLVGCGKERELGERQYKEIIQKTISTLNETGSMEAVCFLTELHVKGR
EHHHCCHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
DTYWKVRQAVEATKDGLYTFDQFKSNKPETRRPLRKLVFNVPTRRELSLGEKAISHGLAI
CHHHHHHHHHHHHHCCCEEHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ASGVKASKDLGNMPPNIANPAYLASQARKLVAWPMITRQ
HHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPVAEQLDKISDGYISSLLRRGDLEGKPGQML
CCCCCCCCCCHHHCCEEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEE
LLHQVPGVLSERVLLVGCGKERELGERQYKEIIQKTISTLNETGSMEAVCFLTELHVKGR
EHHHCCHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
DTYWKVRQAVEATKDGLYTFDQFKSNKPETRRPLRKLVFNVPTRRELSLGEKAISHGLAI
CHHHHHHHHHHHHHCCCEEHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ASGVKASKDLGNMPPNIANPAYLASQARKLVAWPMITRQ
HHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA