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The map label for this gene is yggW [H]

Identifier: 218710635

GI number: 218710635

Start: 2875065

End: 2876252

Strand: Direct

Name: yggW [H]

Synonym: VS_2689

Alternate gene names: 218710635

Gene position: 2875065-2876252 (Clockwise)

Preceding gene: 218710634

Following gene: 218710638

Centisome position: 87.14

GC content: 45.2

Gene sequence:

>1188_bases
ATGCACAATGCAGCGCTAATACCACCCGCACTCAGCCTCTATGTCCACATTCCATGGTGTGTACAAAAGTGTCCGTATTG
TGATTTTAACTCTCACGCTCTCAAAGCCGAGATTCCTGAAAAAGAGTACATCGATGCTCTGCTTGAGGATCTCGATACCG
ATATCGAAAAATACCAACTCAATGGCGCACCTCGCCCATTGCATTCGATCTTTATTGGTGGCGGCACGCCGAGTCTATTT
TCTCCAGAAGGAATAGGTCGATTGCTGCAAGGCATTGAACAACGCATCCCGTTCAAACCTGAAATAGAAATCACCATGGA
AGCTAATCCGGGAACTATCGAAGCTGAGCGTTTTGCTGGTTACCAAAAAGCAGGCATAACTCGAATCTCGGTGGGAGTGC
AAAGTTTTGAACAAGAGAAACTGGAAAGGCTTGGGCGTATTCACGGTCAAGATGAAGCGGTCAACGCAGCTCATTTAGCA
CATAAAATCGGACTAAATAGCTTCAACCTAGATCTAATGCACGGCTTACCCGATCAAAGCATTGATCAGGCCTTGGCTGA
TTTGGACAGAGCGATCGAGCTTAATCCTCCGCATTTATCTTGGTATCAGCTAACAATAGAACCTAACACCATGTTCTATT
ACAAAACGCCAAAGCTGCCTGACGATGATGACCTTTGGGATATTTTCGACTTAGGCCATAAGAAGCTCGCAGACGCAGGT
TATGTACAGTACGAAATTTCAGGCTACAGCAAGCCGGGATATCAGTGTCAGCATAATCTCAACTACTGGCGCTTTGGTGA
CTACCTAGGTATTGGCTGTGGCTCTCATGGCAAGCTAAGCTTTGCAGATGGACGTATTGTTCGCACCACTAAGGTTAAAC
ACCCTAGAGGCTACCTAGCCGCGTATCAGAATCTGGTGAAGCCCTATCTGTCGGATGAACTTGAAGTACCTAATGAGGAC
CGCCCTTTCGAGTTCTTTATGAATCGATTCAGGCTAATGGAAGCATGTCCAAAGCAGGATTTCATTGATACAACTGGGTT
AGAATTTGATTCGATTCAACCAACAATAGAGTGGGCCAAAGATCTCGGTTATCTTAATGAAACCGACAGCCATTGGCAGA
TCACTGAAAAAGGAAAACTCTTCTTAAACGATTTGCTTGAAGCCTTTATGGCAGAAGAAGACGAATAG

Upstream 100 bases:

>100_bases
GCGCCTCAGCAGAACTTGAATCGTCACGTAAGAAGCAACTGTCACACCGTGGTAAAGCCCTCGCGTCATTATTCAAGACT
CTCAAGGAGCAAGCTCTGTA

Downstream 100 bases:

>100_bases
TTCGAACGCTAGAATGCAAAAAGTCTCTCATCACGAGAGGCTTTTTTTGTCGAACTTAGAACTTAGAAAATAGAGCGACC
AATACGCTCTGAGAGTAATT

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MHNAALIPPALSLYVHIPWCVQKCPYCDFNSHALKAEIPEKEYIDALLEDLDTDIEKYQLNGAPRPLHSIFIGGGTPSLF
SPEGIGRLLQGIEQRIPFKPEIEITMEANPGTIEAERFAGYQKAGITRISVGVQSFEQEKLERLGRIHGQDEAVNAAHLA
HKIGLNSFNLDLMHGLPDQSIDQALADLDRAIELNPPHLSWYQLTIEPNTMFYYKTPKLPDDDDLWDIFDLGHKKLADAG
YVQYEISGYSKPGYQCQHNLNYWRFGDYLGIGCGSHGKLSFADGRIVRTTKVKHPRGYLAAYQNLVKPYLSDELEVPNED
RPFEFFMNRFRLMEACPKQDFIDTTGLEFDSIQPTIEWAKDLGYLNETDSHWQITEKGKLFLNDLLEAFMAEEDE

Sequences:

>Translated_395_residues
MHNAALIPPALSLYVHIPWCVQKCPYCDFNSHALKAEIPEKEYIDALLEDLDTDIEKYQLNGAPRPLHSIFIGGGTPSLF
SPEGIGRLLQGIEQRIPFKPEIEITMEANPGTIEAERFAGYQKAGITRISVGVQSFEQEKLERLGRIHGQDEAVNAAHLA
HKIGLNSFNLDLMHGLPDQSIDQALADLDRAIELNPPHLSWYQLTIEPNTMFYYKTPKLPDDDDLWDIFDLGHKKLADAG
YVQYEISGYSKPGYQCQHNLNYWRFGDYLGIGCGSHGKLSFADGRIVRTTKVKHPRGYLAAYQNLVKPYLSDELEVPNED
RPFEFFMNRFRLMEACPKQDFIDTTGLEFDSIQPTIEWAKDLGYLNETDSHWQITEKGKLFLNDLLEAFMAEEDE
>Mature_395_residues
MHNAALIPPALSLYVHIPWCVQKCPYCDFNSHALKAEIPEKEYIDALLEDLDTDIEKYQLNGAPRPLHSIFIGGGTPSLF
SPEGIGRLLQGIEQRIPFKPEIEITMEANPGTIEAERFAGYQKAGITRISVGVQSFEQEKLERLGRIHGQDEAVNAAHLA
HKIGLNSFNLDLMHGLPDQSIDQALADLDRAIELNPPHLSWYQLTIEPNTMFYYKTPKLPDDDDLWDIFDLGHKKLADAG
YVQYEISGYSKPGYQCQHNLNYWRFGDYLGIGCGSHGKLSFADGRIVRTTKVKHPRGYLAAYQNLVKPYLSDELEVPNED
RPFEFFMNRFRLMEACPKQDFIDTTGLEFDSIQPTIEWAKDLGYLNETDSHWQITEKGKLFLNDLLEAFMAEEDE

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=273, Percent_Identity=34.4322344322344, Blast_Score=178, Evalue=8e-45,
Organism=Escherichia coli, GI1789325, Length=384, Percent_Identity=63.5416666666667, Blast_Score=513, Evalue=1e-147,
Organism=Escherichia coli, GI87082341, Length=247, Percent_Identity=31.1740890688259, Blast_Score=111, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 44986; Mature: 44986

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNAALIPPALSLYVHIPWCVQKCPYCDFNSHALKAEIPEKEYIDALLEDLDTDIEKYQL
CCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCHHHEEC
NGAPRPLHSIFIGGGTPSLFSPEGIGRLLQGIEQRIPFKPEIEITMEANPGTIEAERFAG
CCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHCC
YQKAGITRISVGVQSFEQEKLERLGRIHGQDEAVNAAHLAHKIGLNSFNLDLMHGLPDQS
HHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCHH
IDQALADLDRAIELNPPHLSWYQLTIEPNTMFYYKTPKLPDDDDLWDIFDLGHKKLADAG
HHHHHHHHHHHEECCCCCCEEEEEEEECCEEEEEECCCCCCCCCCHHHHHCCHHHHCCCC
YVQYEISGYSKPGYQCQHNLNYWRFGDYLGIGCGSHGKLSFADGRIVRTTKVKHPRGYLA
EEEEEECCCCCCCCCEECCCCEEEECCEEEECCCCCCCEEECCCEEEEEEECCCCCHHHH
AYQNLVKPYLSDELEVPNEDRPFEFFMNRFRLMEACPKQDFIDTTGLEFDSIQPTIEWAK
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
DLGYLNETDSHWQITEKGKLFLNDLLEAFMAEEDE
HCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHNAALIPPALSLYVHIPWCVQKCPYCDFNSHALKAEIPEKEYIDALLEDLDTDIEKYQL
CCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCHHHEEC
NGAPRPLHSIFIGGGTPSLFSPEGIGRLLQGIEQRIPFKPEIEITMEANPGTIEAERFAG
CCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHCC
YQKAGITRISVGVQSFEQEKLERLGRIHGQDEAVNAAHLAHKIGLNSFNLDLMHGLPDQS
HHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCHH
IDQALADLDRAIELNPPHLSWYQLTIEPNTMFYYKTPKLPDDDDLWDIFDLGHKKLADAG
HHHHHHHHHHHEECCCCCCEEEEEEEECCEEEEEECCCCCCCCCCHHHHHCCHHHHCCCC
YVQYEISGYSKPGYQCQHNLNYWRFGDYLGIGCGSHGKLSFADGRIVRTTKVKHPRGYLA
EEEEEECCCCCCCCCEECCCCEEEECCEEEECCCCCCCEEECCCEEEEEEECCCCCHHHH
AYQNLVKPYLSDELEVPNEDRPFEFFMNRFRLMEACPKQDFIDTTGLEFDSIQPTIEWAK
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
DLGYLNETDSHWQITEKGKLFLNDLLEAFMAEEDE
HCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]