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The map label for this gene is ompR [H]

Identifier: 218710599

GI number: 218710599

Start: 2839208

End: 2839942

Strand: Reverse

Name: ompR [H]

Synonym: VS_2652

Alternate gene names: 218710599

Gene position: 2839942-2839208 (Counterclockwise)

Preceding gene: 218710601

Following gene: 218710598

Centisome position: 86.08

GC content: 41.09

Gene sequence:

>735_bases
TTGTTTTCATATGAAAGGTCTAGCATGACAAACAAAGTAATCTTGGTGGTCGATGATAGTCAGGACATTCTTGATGCTCT
TAGTGAATATCTGGAACGTTCAAGCTTTACGGTTATCACAGCTCTTGAAGGCAATGAGATGTGGAAGAAGCTTGAAATTG
TCACTCCAGATCTCATTATTTTAGACATCATGCTACCCGGAGATGATGGTTTGACCTTGTGCCAGAAACTACGTCTTCAA
TCTCAAGTTCCCATTATTATGCTCACCGCAGTAACCGACGATGCTGATCGAATAGCAGGATTAGAAATTGGAGCTGATGA
CTATATTACTAAGTCATTTAACCCACGTGAGCTATTAGCCAGAATCAAAGCTTTATTGAGGCGTTCCACGTTTAGCCATA
GCCAAGGTGAACGGACTCTGAAATTCATGGATTGGACTTTTGACACTCTTAAACGACAACTGAAACATGAAGATGGAGAG
GTGGTATCTCTTTCTAGTGCTGACTATAACTTGCTTACGCTCATGTTGGATTCCCCCAACCAATTATTAAGCCGAAATGA
TATTGCTCAAGCTCTTTGGGGGAGGGATGCGGAACCACTAGAAAGAGGCATTGATGTACAAATTAGCCGGTTAAGGAAGC
AATTAAGAGACGATGACCGTAACACGATTATGACGGTAAGGCATCGCGGCTATATGTTAGTGATCGATTCACATATCAAT
CGTATTAAATTTTGA

Upstream 100 bases:

>100_bases
ATAGAGTCATTTGTAACGAACAGCTTACATTGCGGAGTTTGAGCGCATTTCGTTATTAATATTCTTGAAAGATATAACGA
AGTAAGAGAATGTTGGCGCG

Downstream 100 bases:

>100_bases
AAAAAAACATACACCAGTCAATGGTTGCGCGTATCACCCTGTCTACGTTCATGGTTATTCTCATGGCTGAAATACTGGCA
GGTGCGGTATGGTTTACGGC

Product: putative response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MFSYERSSMTNKVILVVDDSQDILDALSEYLERSSFTVITALEGNEMWKKLEIVTPDLIILDIMLPGDDGLTLCQKLRLQ
SQVPIIMLTAVTDDADRIAGLEIGADDYITKSFNPRELLARIKALLRRSTFSHSQGERTLKFMDWTFDTLKRQLKHEDGE
VVSLSSADYNLLTLMLDSPNQLLSRNDIAQALWGRDAEPLERGIDVQISRLRKQLRDDDRNTIMTVRHRGYMLVIDSHIN
RIKF

Sequences:

>Translated_244_residues
MFSYERSSMTNKVILVVDDSQDILDALSEYLERSSFTVITALEGNEMWKKLEIVTPDLIILDIMLPGDDGLTLCQKLRLQ
SQVPIIMLTAVTDDADRIAGLEIGADDYITKSFNPRELLARIKALLRRSTFSHSQGERTLKFMDWTFDTLKRQLKHEDGE
VVSLSSADYNLLTLMLDSPNQLLSRNDIAQALWGRDAEPLERGIDVQISRLRKQLRDDDRNTIMTVRHRGYMLVIDSHIN
RIKF
>Mature_244_residues
MFSYERSSMTNKVILVVDDSQDILDALSEYLERSSFTVITALEGNEMWKKLEIVTPDLIILDIMLPGDDGLTLCQKLRLQ
SQVPIIMLTAVTDDADRIAGLEIGADDYITKSFNPRELLARIKALLRRSTFSHSQGERTLKFMDWTFDTLKRQLKHEDGE
VVSLSSADYNLLTLMLDSPNQLLSRNDIAQALWGRDAEPLERGIDVQISRLRKQLRDDDRNTIMTVRHRGYMLVIDSHIN
RIKF

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=42.3076923076923, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=40.2597402597403, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=35.3191489361702, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=36.322869955157, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=35.2678571428571, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=35.3711790393013, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=33.7719298245614, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=32.6359832635983, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=34.6846846846847, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1786911, Length=210, Percent_Identity=33.8095238095238, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=32.8888888888889, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=32.5892857142857, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=32.579185520362, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=31.8385650224215, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790299, Length=143, Percent_Identity=29.3706293706294, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28017; Mature: 28017

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSYERSSMTNKVILVVDDSQDILDALSEYLERSSFTVITALEGNEMWKKLEIVTPDLII
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHEECCCCEEE
LDIMLPGDDGLTLCQKLRLQSQVPIIMLTAVTDDADRIAGLEIGADDYITKSFNPRELLA
EEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHEEEEECCCCCEECCCCHHHHHH
RIKALLRRSTFSHSQGERTLKFMDWTFDTLKRQLKHEDGEVVSLSSADYNLLTLMLDSPN
HHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCEEEECCCCCEEEEEEECCCH
QLLSRNDIAQALWGRDAEPLERGIDVQISRLRKQLRDDDRNTIMTVRHRGYMLVIDSHIN
HHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCHH
RIKF
HCCC
>Mature Secondary Structure
MFSYERSSMTNKVILVVDDSQDILDALSEYLERSSFTVITALEGNEMWKKLEIVTPDLII
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHEECCCCEEE
LDIMLPGDDGLTLCQKLRLQSQVPIIMLTAVTDDADRIAGLEIGADDYITKSFNPRELLA
EEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHEEEEECCCCCEECCCCHHHHHH
RIKALLRRSTFSHSQGERTLKFMDWTFDTLKRQLKHEDGEVVSLSSADYNLLTLMLDSPN
HHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCEEEECCCCCEEEEEEECCCH
QLLSRNDIAQALWGRDAEPLERGIDVQISRLRKQLRDDDRNTIMTVRHRGYMLVIDSHIN
HHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCHH
RIKF
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]