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The map label for this gene is ygfA [H]

Identifier: 218710587

GI number: 218710587

Start: 2824184

End: 2824783

Strand: Direct

Name: ygfA [H]

Synonym: VS_2638

Alternate gene names: 218710587

Gene position: 2824184-2824783 (Clockwise)

Preceding gene: 218710586

Following gene: 218710588

Centisome position: 85.6

GC content: 46.5

Gene sequence:

>600_bases
ATGAAGACGCTCACACGCAGCGAATTTCGCAAACAGATCCGCATCAAACGTAACTCCCTATCTAGCGAACAACAAACTCA
ATCCGGGATAGACTTAGTTAAGCAGTGTGCTCAGCTTGATGAAATTCAGTCGGCTCAACATATAGCCCTCTATATTTCGA
TTGATGGCGAACTCGATACCCAGCCTTTAATTGAATGGTTATGGGCGCAAGGTAAGCAAACTTATTTACCAGTATTACAC
CCCTTCTCTACCGGACATCTGCTGTTTCTGCACTACTCGCCAAGCACACCGACGGTTTTGAATAAGTACGGAATCGTTGA
ACCTCAGCTCAATCAATTACTCGTCAAACCATGCCAACAACTCGATCTAATTCTCACACCATTGGTGGGCTTTGACTCTC
AGGGGCATCGCTTAGGCATGGGCGGTGGATATTACGATCGCACCTTGGCTCGATGGTTCGAGACGGGCAATGGCGCAACA
CCTATTGGCCTTGCTCACGATTGCCAACATGTCGATCGTTTACCAATTGAAGGTTGGGACATTCCGTTACCTAAAATCGT
GACTCCGAGTAAAACTTGGCAATGGGAAAACAACCATTAA

Upstream 100 bases:

>100_bases
CGGTCCGCCGAGAAGCCTACGGTAATCATTGCTGATCCGCCTTGAACTCGCTGGTTCAAGGGCCATCTATTCTCAACGGC
ACTTTGGGGTATCCCTTCTT

Downstream 100 bases:

>100_bases
AGCGCTATAATCGCGCCGCAAACGTTAACCTCGATATCCAAAAGTTACCCCAATATCTAAACGTTAACTTTATCATCACG
CAAACGATTAATTCAAAGCG

Product: putative 5-formyltetrahydrofolate cyclo-ligase-family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MKTLTRSEFRKQIRIKRNSLSSEQQTQSGIDLVKQCAQLDEIQSAQHIALYISIDGELDTQPLIEWLWAQGKQTYLPVLH
PFSTGHLLFLHYSPSTPTVLNKYGIVEPQLNQLLVKPCQQLDLILTPLVGFDSQGHRLGMGGGYYDRTLARWFETGNGAT
PIGLAHDCQHVDRLPIEGWDIPLPKIVTPSKTWQWENNH

Sequences:

>Translated_199_residues
MKTLTRSEFRKQIRIKRNSLSSEQQTQSGIDLVKQCAQLDEIQSAQHIALYISIDGELDTQPLIEWLWAQGKQTYLPVLH
PFSTGHLLFLHYSPSTPTVLNKYGIVEPQLNQLLVKPCQQLDLILTPLVGFDSQGHRLGMGGGYYDRTLARWFETGNGAT
PIGLAHDCQHVDRLPIEGWDIPLPKIVTPSKTWQWENNH
>Mature_199_residues
MKTLTRSEFRKQIRIKRNSLSSEQQTQSGIDLVKQCAQLDEIQSAQHIALYISIDGELDTQPLIEWLWAQGKQTYLPVLH
PFSTGHLLFLHYSPSTPTVLNKYGIVEPQLNQLLVKPCQQLDLILTPLVGFDSQGHRLGMGGGYYDRTLARWFETGNGAT
PIGLAHDCQHVDRLPIEGWDIPLPKIVTPSKTWQWENNH

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=192, Percent_Identity=26.0416666666667, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1789278, Length=183, Percent_Identity=52.4590163934426, Blast_Score=202, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 22622; Mature: 22622

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLTRSEFRKQIRIKRNSLSSEQQTQSGIDLVKQCAQLDEIQSAQHIALYISIDGELDT
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCH
QPLIEWLWAQGKQTYLPVLHPFSTGHLLFLHYSPSTPTVLNKYGIVEPQLNQLLVKPCQQ
HHHHHHHHHCCCCCCCCEECCCCCCCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHH
LDLILTPLVGFDSQGHRLGMGGGYYDRTLARWFETGNGATPIGLAHDCQHVDRLPIEGWD
HHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCC
IPLPKIVTPSKTWQWENNH
CCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MKTLTRSEFRKQIRIKRNSLSSEQQTQSGIDLVKQCAQLDEIQSAQHIALYISIDGELDT
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCH
QPLIEWLWAQGKQTYLPVLHPFSTGHLLFLHYSPSTPTVLNKYGIVEPQLNQLLVKPCQQ
HHHHHHHHHCCCCCCCCEECCCCCCCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHH
LDLILTPLVGFDSQGHRLGMGGGYYDRTLARWFETGNGATPIGLAHDCQHVDRLPIEGWD
HHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCC
IPLPKIVTPSKTWQWENNH
CCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]