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The map label for this gene is rpiA

Identifier: 218710588

GI number: 218710588

Start: 2824908

End: 2825564

Strand: Direct

Name: rpiA

Synonym: VS_2639

Alternate gene names: 218710588

Gene position: 2824908-2825564 (Clockwise)

Preceding gene: 218710587

Following gene: 218710589

Centisome position: 85.62

GC content: 45.51

Gene sequence:

>657_bases
ATGACTCAAGATGAAATGAAAAAAGCAGCGGGCTGGGCAGCACTTCAATATGTTGAAGAAGGCAGCATTGTAGGTGTAGG
TACTGGCTCAACAGTAAATCACTTCATCGACGCACTTGGCACAATGAAAGACAAAATCAAGGGTGCGGTTTCAAGCTCTA
TAGCCTCTACTGAAAAACTAGAAGCGCTAGAAATCAAAGTATTCGAATGCAACGACGTATTCAAGCTAGACATCTATGTT
GATGGCGCTGACGAGATTAACGGTTCTCGCGATATGATCAAAGGCGGCGGCGCTGCTTTGACTCGTGAAAAAATCGTAGC
AGCTATCTCTGATAAGTTTATTTGTATCGTTGATGGTACCAAAGCAGTTGATGTGTTGGGTAAATTCCCACTGCCTGTTG
AAGTTATCCCAATGGCACGTTCATACGTAGCTCGTGAACTCGTAAAACTTGGTGGTGACCCAGTTTACCGCGAAGGCTGT
ACAACCGATAACGGCAACGTGATCCTCGATGTGTACGGCATGGCGATCGAAAATCCAAAACAGCTAGAAGATATCATCAA
TGGCATCGCTGGTGTGGTAACGGTTGGTCTGTTCGCTCACCGTGGTGCTGATGTAGTTATCACTGGCACGCCTGAAGGTG
CAAAAATCGAAGAATAA

Upstream 100 bases:

>100_bases
TTAACCTCGATATCCAAAAGTTACCCCAATATCTAAACGTTAACTTTATCATCACGCAAACGATTAATTCAAAGCGCAAG
ACCTTATTCAGGAGAATGGC

Downstream 100 bases:

>100_bases
ATTATAGAAGATTGAGTTTTTCTGTTACTTCATTACAGACGGTGCCCTAGGGCGCCGTTTTTTTTGCTTTATTGCTGTAA
AATTATGTCTTATTCCGTAA

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTQDEMKKAAGWAALQYVEEGSIVGVGTGSTVNHFIDALGTMKDKIKGAVSSSIASTEKLEALEIKVFECNDVFKLDIYV
DGADEINGSRDMIKGGGAALTREKIVAAISDKFICIVDGTKAVDVLGKFPLPVEVIPMARSYVARELVKLGGDPVYREGC
TTDNGNVILDVYGMAIENPKQLEDIINGIAGVVTVGLFAHRGADVVITGTPEGAKIEE

Sequences:

>Translated_218_residues
MTQDEMKKAAGWAALQYVEEGSIVGVGTGSTVNHFIDALGTMKDKIKGAVSSSIASTEKLEALEIKVFECNDVFKLDIYV
DGADEINGSRDMIKGGGAALTREKIVAAISDKFICIVDGTKAVDVLGKFPLPVEVIPMARSYVARELVKLGGDPVYREGC
TTDNGNVILDVYGMAIENPKQLEDIINGIAGVVTVGLFAHRGADVVITGTPEGAKIEE
>Mature_217_residues
TQDEMKKAAGWAALQYVEEGSIVGVGTGSTVNHFIDALGTMKDKIKGAVSSSIASTEKLEALEIKVFECNDVFKLDIYVD
GADEINGSRDMIKGGGAALTREKIVAAISDKFICIVDGTKAVDVLGKFPLPVEVIPMARSYVARELVKLGGDPVYREGCT
TDNGNVILDVYGMAIENPKQLEDIINGIAGVVTVGLFAHRGADVVITGTPEGAKIEE

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=228, Percent_Identity=32.8947368421053, Blast_Score=95, Evalue=5e-20,
Organism=Escherichia coli, GI1789280, Length=215, Percent_Identity=73.0232558139535, Blast_Score=318, Evalue=2e-88,
Organism=Caenorhabditis elegans, GI17551758, Length=210, Percent_Identity=32.8571428571429, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324669, Length=224, Percent_Identity=29.9107142857143, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281364072, Length=209, Percent_Identity=31.5789473684211, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_VIBSL (B7VK98)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002418209.1
- ProteinModelPortal:   B7VK98
- GeneID:   7162157
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2639
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23094; Mature: 22963

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDEMKKAAGWAALQYVEEGSIVGVGTGSTVNHFIDALGTMKDKIKGAVSSSIASTEKL
CCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
EALEIKVFECNDVFKLDIYVDGADEINGSRDMIKGGGAALTREKIVAAISDKFICIVDGT
EEEEEEEEECCCEEEEEEEECCHHHCCCCHHHHCCCCCHHHHHHHHHHHCCCEEEEECCC
KAVDVLGKFPLPVEVIPMARSYVARELVKLGGDPVYREGCTTDNGNVILDVYGMAIENPK
HHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCEEEEEECCCCCCHH
QLEDIINGIAGVVTVGLFAHRGADVVITGTPEGAKIEE
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TQDEMKKAAGWAALQYVEEGSIVGVGTGSTVNHFIDALGTMKDKIKGAVSSSIASTEKL
CHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
EALEIKVFECNDVFKLDIYVDGADEINGSRDMIKGGGAALTREKIVAAISDKFICIVDGT
EEEEEEEEECCCEEEEEEEECCHHHCCCCHHHHCCCCCHHHHHHHHHHHCCCEEEEECCC
KAVDVLGKFPLPVEVIPMARSYVARELVKLGGDPVYREGCTTDNGNVILDVYGMAIENPK
HHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCEEEEEECCCCCCHH
QLEDIINGIAGVVTVGLFAHRGADVVITGTPEGAKIEE
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA