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The map label for this gene is visC [H]

Identifier: 218710583

GI number: 218710583

Start: 2820354

End: 2821577

Strand: Reverse

Name: visC [H]

Synonym: VS_2633

Alternate gene names: 218710583

Gene position: 2821577-2820354 (Counterclockwise)

Preceding gene: 218710584

Following gene: 218710579

Centisome position: 85.52

GC content: 50.0

Gene sequence:

>1224_bases
ATGATGCAAAGTGTTGATATCGCGATTGTTGGCGGTGGCATGGTTGGCCTAGCGCTTGCGGCTGCACTGAAAGACAGCGA
TCTAAGAATTGCGGTCATTGAAGGCAGAGCGCCTAGCGAAGGGCTTAGCGAATTGCCTGATGTGCGTGTGTCGGCATTGA
GCCGCTCGAGTGAAGTGATTCTTCGCAATCTAGGCGCATGGCAAGGTATCGAACAAAGACGTGCTGCGCCCTACCAAGCG
ATGGAAGTGTGGGAACAAGACAGCTTTGCTCGCATTGAGTTTGACTCAACACGCTTAGCACAGCCTAACCTAGGCCATAT
TGTAGAAAACCGCGTAATCCAATTAGCGCTGCTTGATCAGGTTAAGAAGCAAGATAATGTCAGCCTATACATGCCTGCAA
CGTGTAAAACGATGGCGATTGGTGAGAGCGAAGCATGGCTAACGTTAGACAACGGCCAAGCGCTGACAGCAAAGTTAGTT
GTTGGAGCTGACGGTGCAAACTCTTGGGTTCGCAAGCAACAAGATATCCCATTAACTCATTGGGATTACGGCCACAGTGC
GATTGTCGCGAACATCAAAACCTCAGAGCAGCACCATAGCGTTGCTCGTCAAATATTTACACCTCAAGGCCCATTGGCGT
TCCTGCCAATGCAACCAACGAATATGAGCTCGATTGTTTGGTCTACGGAGCCTAATCGTGCCGAGAAGCTTGTATCAATG
TCGGATGCTGATTTTAATAAGCAGCTAACGGCAGAGTTCGACTCAAAACTTGGTTTATGCGAAGTGGTTGGTGACCGTTT
TGCCTTCCCACTGCGCATGCGTTATGCACGTGACTTTGCTGTAGAGCGTGTCGCTTTGGTGGGGGATGCAGCTCATACTA
TTCACCCATTAGCAGGGCAAGGCGTGAACCTTGGTCTATTAGACGCAGCAAGCTTAGCGCAAGAGCTGTTAACGCTATGG
GCTTCTGGTGAGGATATTGGCACCAAGCGCAACCTTCGTGGCTATGAGCGCTGGAGAAAAGCTGAGGCGGCGAAAATGAT
TGCTTCAATGCAGGGCTTTAAAGATCTGTTTGAAGGCGATAATCCGGCTAAGAAGCTAATTCGTGGTATCGGTATGAAGC
TTGCTGGTCAATTACCGGGTGCGAAAGATGAGATAATGAAGCGAGCGCTGGGTTTGTCGGGCAATCTTCCGGATTTAGCT
AAGCGCCCCGTAGCACACCGATAG

Upstream 100 bases:

>100_bases
GGCGAAACCTTGGGTTAGCCGTAATTGATAACCTTCCACCACTTAAAGGTCCACTTTTGCGTCATACGCTTGGCCTAGTA
GAAAGATAAGGTAATAAATA

Downstream 100 bases:

>100_bases
TCGCGTGAGATGGATTGCTGTTGATGGTCAGTAGCTAAAGTTGATAGCAATTGACGACATCAAGAACACGAAAAAAGGGT
TGGCATTATGCCAACCCTTT

Product: 2-octaprenyl-6-methoxyphenol hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MMQSVDIAIVGGGMVGLALAAALKDSDLRIAVIEGRAPSEGLSELPDVRVSALSRSSEVILRNLGAWQGIEQRRAAPYQA
MEVWEQDSFARIEFDSTRLAQPNLGHIVENRVIQLALLDQVKKQDNVSLYMPATCKTMAIGESEAWLTLDNGQALTAKLV
VGADGANSWVRKQQDIPLTHWDYGHSAIVANIKTSEQHHSVARQIFTPQGPLAFLPMQPTNMSSIVWSTEPNRAEKLVSM
SDADFNKQLTAEFDSKLGLCEVVGDRFAFPLRMRYARDFAVERVALVGDAAHTIHPLAGQGVNLGLLDAASLAQELLTLW
ASGEDIGTKRNLRGYERWRKAEAAKMIASMQGFKDLFEGDNPAKKLIRGIGMKLAGQLPGAKDEIMKRALGLSGNLPDLA
KRPVAHR

Sequences:

>Translated_407_residues
MMQSVDIAIVGGGMVGLALAAALKDSDLRIAVIEGRAPSEGLSELPDVRVSALSRSSEVILRNLGAWQGIEQRRAAPYQA
MEVWEQDSFARIEFDSTRLAQPNLGHIVENRVIQLALLDQVKKQDNVSLYMPATCKTMAIGESEAWLTLDNGQALTAKLV
VGADGANSWVRKQQDIPLTHWDYGHSAIVANIKTSEQHHSVARQIFTPQGPLAFLPMQPTNMSSIVWSTEPNRAEKLVSM
SDADFNKQLTAEFDSKLGLCEVVGDRFAFPLRMRYARDFAVERVALVGDAAHTIHPLAGQGVNLGLLDAASLAQELLTLW
ASGEDIGTKRNLRGYERWRKAEAAKMIASMQGFKDLFEGDNPAKKLIRGIGMKLAGQLPGAKDEIMKRALGLSGNLPDLA
KRPVAHR
>Mature_407_residues
MMQSVDIAIVGGGMVGLALAAALKDSDLRIAVIEGRAPSEGLSELPDVRVSALSRSSEVILRNLGAWQGIEQRRAAPYQA
MEVWEQDSFARIEFDSTRLAQPNLGHIVENRVIQLALLDQVKKQDNVSLYMPATCKTMAIGESEAWLTLDNGQALTAKLV
VGADGANSWVRKQQDIPLTHWDYGHSAIVANIKTSEQHHSVARQIFTPQGPLAFLPMQPTNMSSIVWSTEPNRAEKLVSM
SDADFNKQLTAEFDSKLGLCEVVGDRFAFPLRMRYARDFAVERVALVGDAAHTIHPLAGQGVNLGLLDAASLAQELLTLW
ASGEDIGTKRNLRGYERWRKAEAAKMIASMQGFKDLFEGDNPAKKLIRGIGMKLAGQLPGAKDEIMKRALGLSGNLPDLA
KRPVAHR

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=420, Percent_Identity=33.3333333333333, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI32967307, Length=350, Percent_Identity=34, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI1789273, Length=398, Percent_Identity=54.2713567839196, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI1786883, Length=391, Percent_Identity=37.5959079283887, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI1789274, Length=390, Percent_Identity=31.2820512820513, Blast_Score=172, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI25146631, Length=431, Percent_Identity=30.3944315545244, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6321694, Length=452, Percent_Identity=27.8761061946903, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI19920760, Length=421, Percent_Identity=31.353919239905, Blast_Score=184, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 44484; Mature: 44484

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQSVDIAIVGGGMVGLALAAALKDSDLRIAVIEGRAPSEGLSELPDVRVSALSRSSEVI
CCCEEEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCHHHHHHCCHHHHH
LRNLGAWQGIEQRRAAPYQAMEVWEQDSFARIEFDSTRLAQPNLGHIVENRVIQLALLDQ
HHHCCHHCCHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
VKKQDNVSLYMPATCKTMAIGESEAWLTLDNGQALTAKLVVGADGANSWVRKQQDIPLTH
HHCCCCCEEEECCCEEEEEECCCCCEEEECCCCEEEEEEEEECCCCHHHHHHCCCCCCEE
WDYGHSAIVANIKTSEQHHSVARQIFTPQGPLAFLPMQPTNMSSIVWSTEPNRAEKLVSM
CCCCCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHC
SDADFNKQLTAEFDSKLGLCEVVGDRFAFPLRMRYARDFAVERVALVGDAAHTIHPLAGQ
CCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
GVNLGLLDAASLAQELLTLWASGEDIGTKRNLRGYERWRKAEAAKMIASMQGFKDLFEGD
CCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPAKKLIRGIGMKLAGQLPGAKDEIMKRALGLSGNLPDLAKRPVAHR
CHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MMQSVDIAIVGGGMVGLALAAALKDSDLRIAVIEGRAPSEGLSELPDVRVSALSRSSEVI
CCCEEEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCHHHHHHCCHHHHH
LRNLGAWQGIEQRRAAPYQAMEVWEQDSFARIEFDSTRLAQPNLGHIVENRVIQLALLDQ
HHHCCHHCCHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
VKKQDNVSLYMPATCKTMAIGESEAWLTLDNGQALTAKLVVGADGANSWVRKQQDIPLTH
HHCCCCCEEEECCCEEEEEECCCCCEEEECCCCEEEEEEEEECCCCHHHHHHCCCCCCEE
WDYGHSAIVANIKTSEQHHSVARQIFTPQGPLAFLPMQPTNMSSIVWSTEPNRAEKLVSM
CCCCCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHC
SDADFNKQLTAEFDSKLGLCEVVGDRFAFPLRMRYARDFAVERVALVGDAAHTIHPLAGQ
CCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
GVNLGLLDAASLAQELLTLWASGEDIGTKRNLRGYERWRKAEAAKMIASMQGFKDLFEGD
CCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPAKKLIRGIGMKLAGQLPGAKDEIMKRALGLSGNLPDLAKRPVAHR
CHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]