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The map label for this gene is luxS

Identifier: 218710523

GI number: 218710523

Start: 2751985

End: 2752503

Strand: Reverse

Name: luxS

Synonym: VS_2562

Alternate gene names: 218710523

Gene position: 2752503-2751985 (Counterclockwise)

Preceding gene: 218710524

Following gene: 218710520

Centisome position: 83.43

GC content: 44.89

Gene sequence:

>519_bases
ATGCCTTTATTAGATAGTTTTACTGTTGATCACACGCGCATGAACGCACCTGCAGTTCGTGTTGCTAAAACAATGCAAAC
CCCCAAAGGGGATACCATTACGGTATTTGACCTGCGTTTTACTGCGCCAAACAAAGATATCCTATCTGAGAGAGGTATTC
ATACTCTCGAGCACCTATACGCTGGGTTCATGCGTGCTCACCTCAATGGCTCTGCGGTTGAGATCATTGATATTTCGCCT
ATGGGTTGTCGTACCGGTTTCTATATGAGCTTGATTGGTACGCCTTCAGAGCAGCAAGTGGCTGAAGCTTGGTTAGCGGC
TATGCAAGACGTACTGAAAGTTGAGAACCAGAATAAGATCCCTGAGTTGAACGAATACCAGTGTGGTACTGCGGCAATGC
ATTCCTTAGATGAAGCTAAAGAGATTGCGAATGCAATCATCGCTGCAGGTATCTCTGTAAACAAAAATGATGAACTGGCA
TTGCCAGAGTCGATGCTTCAAGAGCTTAAAATCGACTAA

Upstream 100 bases:

>100_bases
GCAAGCAAAAGATTATGGATGGCAACTTAAACAGTGCCGAAAAGAACTAGAAGACAATCGAAGTTGGTTTTTTTAAAGCC
AATCGTCATGGAGAATAGCA

Downstream 100 bases:

>100_bases
TCACTTTTCTTTACTTTAGATGCGCTTCACTCTAAATACATTTCAATCTAGAGGCAGAGCGAGTTAGATACTAAAAGGCC
CGGTTCAATGAACCGGGCCT

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MPLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSERGIHTLEHLYAGFMRAHLNGSAVEIIDISP
MGCRTGFYMSLIGTPSEQQVAEAWLAAMQDVLKVENQNKIPELNEYQCGTAAMHSLDEAKEIANAIIAAGISVNKNDELA
LPESMLQELKID

Sequences:

>Translated_172_residues
MPLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSERGIHTLEHLYAGFMRAHLNGSAVEIIDISP
MGCRTGFYMSLIGTPSEQQVAEAWLAAMQDVLKVENQNKIPELNEYQCGTAAMHSLDEAKEIANAIIAAGISVNKNDELA
LPESMLQELKID
>Mature_171_residues
PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSERGIHTLEHLYAGFMRAHLNGSAVEIIDISPM
GCRTGFYMSLIGTPSEQQVAEAWLAAMQDVLKVENQNKIPELNEYQCGTAAMHSLDEAKEIANAIIAAGISVNKNDELAL
PESMLQELKID

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=171, Percent_Identity=74.8538011695906, Blast_Score=279, Evalue=8e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_VIBSL (B7VK33)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002418144.1
- GeneID:   7162092
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2562
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- ProtClustDB:   PRK02260
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 18929; Mature: 18798

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSERGIHTLEHLY
CCCCCCCCCCCHHCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHCCHHHHHHHH
AGFMRAHLNGSAVEIIDISPMGCRTGFYMSLIGTPSEQQVAEAWLAAMQDVLKVENQNKI
HHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
PELNEYQCGTAAMHSLDEAKEIANAIIAAGISVNKNDELALPESMLQELKID
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSERGIHTLEHLY
CCCCCCCCCCHHCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHCCHHHHHHHH
AGFMRAHLNGSAVEIIDISPMGCRTGFYMSLIGTPSEQQVAEAWLAAMQDVLKVENQNKI
HHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
PELNEYQCGTAAMHSLDEAKEIANAIIAAGISVNKNDELALPESMLQELKID
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA