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The map label for this gene is ybbO [H]

Identifier: 218710246

GI number: 218710246

Start: 2448591

End: 2449418

Strand: Direct

Name: ybbO [H]

Synonym: VS_2279

Alternate gene names: 218710246

Gene position: 2448591-2449418 (Clockwise)

Preceding gene: 218710245

Following gene: 218710247

Centisome position: 74.22

GC content: 45.53

Gene sequence:

>828_bases
GTGAACAAGTCGATTCTGATCACCGGTTGCTCAACGGGTATTGGCTATACATGTGCGCATGCACTACAAAAGCGTGGTTT
CCACGTCATTGCATCGTGTCGTCATCCGCAAGATGTACAGCGTCTGCAAGATGAGGGACTGACCTGCATACAGCTCGACC
TTTCTAACCAAGAAAGCATTGAACAAGCTGCACAACTTGCTATTGAGCTAGCGCCTAACGGATTATATGGTTTATTCAAT
AACGGCGCTTATGGTCAAGCTGGCGCGCTAGAAGACTTACCAACCCAAGGTCTCAGAGAGCAATTCGAAACCAACTTCTT
TGGCTGGCATCATCTTGTTTGTCAGATACTTCCGCACATGCGCGAACGCGGCGAAGGTCGAATCGTACAAAACAGTTCCG
TATTAGGCTTTGCAGCCATGAAATATCGTGGTGCTTACAACGCTTCAAAGTTCGCGCTAGAAGGCTGGACAGATACGTTA
CGTTTAGAACTGCATGGCAGTGGTATTAATATCTCGTTATTGCAGCCAGGTCCAATAGAAACCCAATTTAGAAATAATGC
CCTGAAAGCTTTCAATAAATGGATCACCATTGCTGGCAGCGCTCATCAAGAAGCTTATCAACAACAAAAAGACCGACTCG
AAAAAGAATCATCGAACAACGCTTTTGTTCTTCCGCCTGAAAGTTGTATTGAACCGGTTTATCACGCACTCACCGCCGAT
AAACCCAAACTCAGATACCGAGTGACGACCCCAACTAAAGTGTTCGCGGTATTGAAAAGAATTCTACCTAGTCGCTTGCT
AGACCCTATTTTGAGAAAAGCTGCATAA

Upstream 100 bases:

>100_bases
TTTAGTTACTCAAGAATAGAACCAGCCTTAAAAAACTTGTTACAACATCAAGATTAATTCTTTACCCTAGAGCGATAAAG
ACTCTAATGAAGGATTAAGC

Downstream 100 bases:

>100_bases
ATTACTAACTTTGCCTCAACAGTCGCAAACTTTAATGTAACGATGTAATTTTTCCGTAACAATAAGATGTCATGATTGTC
CTATCTCATCAATTATTCCC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MNKSILITGCSTGIGYTCAHALQKRGFHVIASCRHPQDVQRLQDEGLTCIQLDLSNQESIEQAAQLAIELAPNGLYGLFN
NGAYGQAGALEDLPTQGLREQFETNFFGWHHLVCQILPHMRERGEGRIVQNSSVLGFAAMKYRGAYNASKFALEGWTDTL
RLELHGSGINISLLQPGPIETQFRNNALKAFNKWITIAGSAHQEAYQQQKDRLEKESSNNAFVLPPESCIEPVYHALTAD
KPKLRYRVTTPTKVFAVLKRILPSRLLDPILRKAA

Sequences:

>Translated_275_residues
MNKSILITGCSTGIGYTCAHALQKRGFHVIASCRHPQDVQRLQDEGLTCIQLDLSNQESIEQAAQLAIELAPNGLYGLFN
NGAYGQAGALEDLPTQGLREQFETNFFGWHHLVCQILPHMRERGEGRIVQNSSVLGFAAMKYRGAYNASKFALEGWTDTL
RLELHGSGINISLLQPGPIETQFRNNALKAFNKWITIAGSAHQEAYQQQKDRLEKESSNNAFVLPPESCIEPVYHALTAD
KPKLRYRVTTPTKVFAVLKRILPSRLLDPILRKAA
>Mature_275_residues
MNKSILITGCSTGIGYTCAHALQKRGFHVIASCRHPQDVQRLQDEGLTCIQLDLSNQESIEQAAQLAIELAPNGLYGLFN
NGAYGQAGALEDLPTQGLREQFETNFFGWHHLVCQILPHMRERGEGRIVQNSSVLGFAAMKYRGAYNASKFALEGWTDTL
RLELHGSGINISLLQPGPIETQFRNNALKAFNKWITIAGSAHQEAYQQQKDRLEKESSNNAFVLPPESCIEPVYHALTAD
KPKLRYRVTTPTKVFAVLKRILPSRLLDPILRKAA

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40548397, Length=283, Percent_Identity=31.095406360424, Blast_Score=127, Evalue=8e-30,
Organism=Homo sapiens, GI214010158, Length=283, Percent_Identity=31.095406360424, Blast_Score=127, Evalue=8e-30,
Organism=Homo sapiens, GI214010156, Length=283, Percent_Identity=31.095406360424, Blast_Score=127, Evalue=8e-30,
Organism=Homo sapiens, GI22758144, Length=283, Percent_Identity=31.095406360424, Blast_Score=127, Evalue=8e-30,
Organism=Homo sapiens, GI19743808, Length=289, Percent_Identity=32.1799307958478, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI7657478, Length=274, Percent_Identity=29.9270072992701, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI150247226, Length=285, Percent_Identity=28.7719298245614, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI50726952, Length=286, Percent_Identity=31.1188811188811, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI22507405, Length=281, Percent_Identity=28.8256227758007, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI44680136, Length=264, Percent_Identity=26.5151515151515, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI44680133, Length=264, Percent_Identity=26.5151515151515, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI17738292, Length=264, Percent_Identity=26.5151515151515, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI223718074, Length=283, Percent_Identity=30.7420494699647, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=32.3076923076923, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI119392083, Length=258, Percent_Identity=29.4573643410853, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI20149619, Length=206, Percent_Identity=29.126213592233, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI32483357, Length=189, Percent_Identity=32.2751322751323, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4504503, Length=199, Percent_Identity=29.6482412060301, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI5031737, Length=188, Percent_Identity=31.9148936170213, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=31.9148936170213, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI32455239, Length=228, Percent_Identity=29.8245614035088, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI5031765, Length=228, Percent_Identity=29.8245614035088, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=30.3867403314917, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786701, Length=273, Percent_Identity=45.0549450549451, Blast_Score=247, Evalue=8e-67,
Organism=Escherichia coli, GI1787820, Length=245, Percent_Identity=27.3469387755102, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082100, Length=197, Percent_Identity=28.4263959390863, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787335, Length=188, Percent_Identity=27.6595744680851, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=283, Percent_Identity=27.9151943462898, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17557780, Length=288, Percent_Identity=26.3888888888889, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193210355, Length=274, Percent_Identity=29.5620437956204, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71997402, Length=215, Percent_Identity=29.7674418604651, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17570069, Length=215, Percent_Identity=29.3023255813954, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32563809, Length=292, Percent_Identity=22.9452054794521, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17507613, Length=292, Percent_Identity=22.9452054794521, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=33.6734693877551, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24651139, Length=188, Percent_Identity=32.4468085106383, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19922066, Length=270, Percent_Identity=24.8148148148148, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24580925, Length=199, Percent_Identity=28.643216080402, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648944, Length=194, Percent_Identity=30.4123711340206, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356301, Length=188, Percent_Identity=25, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24643142, Length=185, Percent_Identity=29.1891891891892, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28571526, Length=190, Percent_Identity=28.4210526315789, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28571387, Length=206, Percent_Identity=28.6407766990291, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24663911, Length=199, Percent_Identity=27.6381909547739, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30627; Mature: 30627

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSILITGCSTGIGYTCAHALQKRGFHVIASCRHPQDVQRLQDEGLTCIQLDLSNQESI
CCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCEEEEEECCCHHHH
EQAAQLAIELAPNGLYGLFNNGAYGQAGALEDLPTQGLREQFETNFFGWHHLVCQILPHM
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHCCHHHHHHHHHCCCCHHHHHHHHHHHHH
RERGEGRIVQNSSVLGFAAMKYRGAYNASKFALEGWTDTLRLELHGSGINISLLQPGPIE
HHCCCCCEEECCCCHHHHHHHHCCCCCCCCEEECCCCEEEEEEEECCCEEEEEECCCCCC
TQFRNNALKAFNKWITIAGSAHQEAYQQQKDRLEKESSNNAFVLPPESCIEPVYHALTAD
HHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCC
KPKLRYRVTTPTKVFAVLKRILPSRLLDPILRKAA
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKSILITGCSTGIGYTCAHALQKRGFHVIASCRHPQDVQRLQDEGLTCIQLDLSNQESI
CCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCEEEEEECCCHHHH
EQAAQLAIELAPNGLYGLFNNGAYGQAGALEDLPTQGLREQFETNFFGWHHLVCQILPHM
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHCCHHHHHHHHHCCCCHHHHHHHHHHHHH
RERGEGRIVQNSSVLGFAAMKYRGAYNASKFALEGWTDTLRLELHGSGINISLLQPGPIE
HHCCCCCEEECCCCHHHHHHHHCCCCCCCCEEECCCCEEEEEEEECCCEEEEEECCCCCC
TQFRNNALKAFNKWITIAGSAHQEAYQQQKDRLEKESSNNAFVLPPESCIEPVYHALTAD
HHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCC
KPKLRYRVTTPTKVFAVLKRILPSRLLDPILRKAA
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]