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The map label for this gene is yclF [H]

Identifier: 218710233

GI number: 218710233

Start: 2436611

End: 2437996

Strand: Direct

Name: yclF [H]

Synonym: VS_2266

Alternate gene names: 218710233

Gene position: 2436611-2437996 (Clockwise)

Preceding gene: 218710231

Following gene: 218710237

Centisome position: 73.85

GC content: 46.1

Gene sequence:

>1386_bases
ATGCCAAGCAATCACAACATCTTTGGCCACCCTAGAGGCCTATTTTTATTATTTAGCACAGAGCTATGGGAACGTTTCTC
CTACTACGCGATGCGTGCCATCCTTGTTTTATTTTTGACTGACACGACCCTCAACGGTGGACTGGGTTGGTCAACGAAAG
ACGCACTTGATCTCTACGGTATTTACACTGGCTTAGTCTACATCACGCCATTGATCGGTGGCTGGATTGCCGATAACTAC
TTAGGACAACGTAAATCGATCCTAGTGGGTGGTGTATTAATGGCACTCGGCCAGTTTACACTCGCTCTTCCTAACGGCGC
TATTGGCTTAGACCAAGTAAATGCTCTTTATCTAGGTTTAGCACTACTTATCAGTGGTAACGGTATGTTTAAGCCAAACA
TCTCGACCATGGTTGGCGACCTATACCAAGAAGGCGATAACCGCCGTGACGGTGCATTCACCATTTTCTACATGGGCATC
AACTTAGGTGCATTATTAGGTGGCTTGATTTCAGGCGCTGCTGTCGACTCTTTCGGCTGGAAAGCAGGTTTCTTAGCCGC
TGGTATTGGTATGGTTATTAGCTTAATCATGCAAATGACAATGGCTCAATCTTGGTTAGGTAACATTGGTTCAGTGCCCG
CAGCTGCGCGAGCAAAAGCACTAAACAAATCAAAAGAAAAAACGCCACTAACCAAAGAAGAGTTCGATCGATTAAAAGTT
ATTCTGGTTATGGGTCTATTCGTCATAGTTTTCTGGGCGGGCTTTGAACAAGCTGGCGGTCTGATGAATATCTATACTCA
ACAATATACTGACCGCATGATTGGTGGCTTTGAAGTCCCAGCGGCGTGGTTCCAATCTCTGAACCCATTCTTCATCATTA
CACTTGCACCAATCATTGCTGCATTTTGGGTTAAGCTTGGTAAGCGTGAACCAAATTCTCCAGTGAAATTTGCAATGGCT
TTGTTCTTCCTAGCTCTTGGTTTTGTGTGCATGATGGGCGCTGTAATGGAGCAAGGTGGCGACCTAACAGTGAAAACATC
AATGCTGTGGCTAGTAGGTGCTTTCTTCTTCCATACCCTTGGCGAACTTTGTCTATCTCCTATTGGCCTGTCGTTGGTCA
CTAAGTTAGCTCCGCTTCGTCTCGCATCGCTAATGATGGGTGCATGGTTTGGCTTCAACGCTGTCGCAAACTACGTCGCT
GGCCTTGTGGGTTCTCACGTTGGGGAGCTTGGCGCAATGTCTATCTTCGGTGGTATCGCAATTACAGCGACAATAAGTGG
CGTCTTACTTCTTCTTTGTGCTGGCAAGCTTGTATCATGGATGCATGGCGTAGAAAGCAACATGATGCTTGAAGCAGAGC
CAAAAGCAGAAACTTCGGTTGCTTAA

Upstream 100 bases:

>100_bases
AGTTATCGTGACCACAAAATACGCCTATTGCAGACTTTTACCCTACTGTGTATACATGAATAACTATAAAATCTTTTAAT
ACCTAAAATTAGTAAAACTT

Downstream 100 bases:

>100_bases
TATCTAGACCTATTTCAAGAAGAAACATCCAGATCAAAAAGGGCTGCTCAATGAGCAGCCCTTTTGTTATTTTTAGATGT
GCATGACAGTTTAGGCGAAG

Product: dipeptide/tripeptide permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MPSNHNIFGHPRGLFLLFSTELWERFSYYAMRAILVLFLTDTTLNGGLGWSTKDALDLYGIYTGLVYITPLIGGWIADNY
LGQRKSILVGGVLMALGQFTLALPNGAIGLDQVNALYLGLALLISGNGMFKPNISTMVGDLYQEGDNRRDGAFTIFYMGI
NLGALLGGLISGAAVDSFGWKAGFLAAGIGMVISLIMQMTMAQSWLGNIGSVPAAARAKALNKSKEKTPLTKEEFDRLKV
ILVMGLFVIVFWAGFEQAGGLMNIYTQQYTDRMIGGFEVPAAWFQSLNPFFIITLAPIIAAFWVKLGKREPNSPVKFAMA
LFFLALGFVCMMGAVMEQGGDLTVKTSMLWLVGAFFFHTLGELCLSPIGLSLVTKLAPLRLASLMMGAWFGFNAVANYVA
GLVGSHVGELGAMSIFGGIAITATISGVLLLLCAGKLVSWMHGVESNMMLEAEPKAETSVA

Sequences:

>Translated_461_residues
MPSNHNIFGHPRGLFLLFSTELWERFSYYAMRAILVLFLTDTTLNGGLGWSTKDALDLYGIYTGLVYITPLIGGWIADNY
LGQRKSILVGGVLMALGQFTLALPNGAIGLDQVNALYLGLALLISGNGMFKPNISTMVGDLYQEGDNRRDGAFTIFYMGI
NLGALLGGLISGAAVDSFGWKAGFLAAGIGMVISLIMQMTMAQSWLGNIGSVPAAARAKALNKSKEKTPLTKEEFDRLKV
ILVMGLFVIVFWAGFEQAGGLMNIYTQQYTDRMIGGFEVPAAWFQSLNPFFIITLAPIIAAFWVKLGKREPNSPVKFAMA
LFFLALGFVCMMGAVMEQGGDLTVKTSMLWLVGAFFFHTLGELCLSPIGLSLVTKLAPLRLASLMMGAWFGFNAVANYVA
GLVGSHVGELGAMSIFGGIAITATISGVLLLLCAGKLVSWMHGVESNMMLEAEPKAETSVA
>Mature_460_residues
PSNHNIFGHPRGLFLLFSTELWERFSYYAMRAILVLFLTDTTLNGGLGWSTKDALDLYGIYTGLVYITPLIGGWIADNYL
GQRKSILVGGVLMALGQFTLALPNGAIGLDQVNALYLGLALLISGNGMFKPNISTMVGDLYQEGDNRRDGAFTIFYMGIN
LGALLGGLISGAAVDSFGWKAGFLAAGIGMVISLIMQMTMAQSWLGNIGSVPAAARAKALNKSKEKTPLTKEEFDRLKVI
LVMGLFVIVFWAGFEQAGGLMNIYTQQYTDRMIGGFEVPAAWFQSLNPFFIITLAPIIAAFWVKLGKREPNSPVKFAMAL
FFLALGFVCMMGAVMEQGGDLTVKTSMLWLVGAFFFHTLGELCLSPIGLSLVTKLAPLRLASLMMGAWFGFNAVANYVAG
LVGSHVGELGAMSIFGGIAITATISGVLLLLCAGKLVSWMHGVESNMMLEAEPKAETSVA

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=348, Percent_Identity=29.3103448275862, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI226371746, Length=328, Percent_Identity=27.1341463414634, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI226371748, Length=325, Percent_Identity=25.5384615384615, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1787922, Length=483, Percent_Identity=29.8136645962733, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1790572, Length=462, Percent_Identity=27.9220779220779, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1789911, Length=438, Percent_Identity=28.0821917808219, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1786927, Length=450, Percent_Identity=26.8888888888889, Blast_Score=181, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71987453, Length=339, Percent_Identity=27.1386430678466, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17569141, Length=378, Percent_Identity=25.3968253968254, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17541704, Length=340, Percent_Identity=27.6470588235294, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322946, Length=483, Percent_Identity=21.9461697722567, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639583, Length=343, Percent_Identity=32.0699708454811, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24639585, Length=343, Percent_Identity=32.0699708454811, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24639581, Length=343, Percent_Identity=32.0699708454811, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28571098, Length=325, Percent_Identity=29.5384615384615, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571102, Length=329, Percent_Identity=28.8753799392097, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28571100, Length=329, Percent_Identity=28.8753799392097, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 49568; Mature: 49437

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSNHNIFGHPRGLFLLFSTELWERFSYYAMRAILVLFLTDTTLNGGLGWSTKDALDLYG
CCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
IYTGLVYITPLIGGWIADNYLGQRKSILVGGVLMALGQFTLALPNGAIGLDQVNALYLGL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHH
ALLISGNGMFKPNISTMVGDLYQEGDNRRDGAFTIFYMGINLGALLGGLISGAAVDSFGW
HHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCC
KAGFLAAGIGMVISLIMQMTMAQSWLGNIGSVPAAARAKALNKSKEKTPLTKEEFDRLKV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHH
ILVMGLFVIVFWAGFEQAGGLMNIYTQQYTDRMIGGFEVPAAWFQSLNPFFIITLAPIIA
HHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEHHHHHHHHH
AFWVKLGKREPNSPVKFAMALFFLALGFVCMMGAVMEQGGDLTVKTSMLWLVGAFFFHTL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHH
GELCLSPIGLSLVTKLAPLRLASLMMGAWFGFNAVANYVAGLVGSHVGELGAMSIFGGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITATISGVLLLLCAGKLVSWMHGVESNMMLEAEPKAETSVA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCC
>Mature Secondary Structure 
PSNHNIFGHPRGLFLLFSTELWERFSYYAMRAILVLFLTDTTLNGGLGWSTKDALDLYG
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]