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The map label for this gene is toxR [H]

Identifier: 218710237

GI number: 218710237

Start: 2442550

End: 2443461

Strand: Direct

Name: toxR [H]

Synonym: VS_2270

Alternate gene names: 218710237

Gene position: 2442550-2443461 (Clockwise)

Preceding gene: 218710233

Following gene: 218710238

Centisome position: 74.03

GC content: 43.75

Gene sequence:

>912_bases
ATGAGCAATATCGGCACAAAGTTTATTCTCGCACAGCGGTTCGTATTTGACCCAAATAGCAACTCACTTGTTGATCAGAT
GAGCGACGGTGAAGTCGTACGTCTTGGCAGCAATGAAAGCCGCATTCTCCTGATGCTGTCAGAAAGACCCAATGAAGTTA
TCACTCGTAACGAATTACACGAATATGTTTGGCGAGACCAAGGCTTTGAGGTGGACGACTCCAGCTTAACGCAAGCGGTA
TCGACACTCAGAAAAATGCTAAAAGACTCAACCAAATCTCCAGCATTTGTAAAAACCGTTCCTAAACGTGGTTATCAATT
TATCGCAACTGTTGAGCGCTCAGCACCACTGTCATCAAACGATCAGCCAACAACAGCTGAAATTGCAGAAAGTGACGTAG
AGCCTATCTTAACATTTGCTAATACCACATTAGCTGATGAGGTCATCACTGAAACTATTGATCCAGAGCCAACTGCAAAG
GCTCAAGAGAATCATGTCAAAGTCGAGCCAGTAACCAATCAGGTTAAGCCTAAAGATGAAAGTTCGAATAAATGGTTAAC
GTTTGGAATGTTACTTGTCGCTTTCATTATGCCAATACTCGTTTTAACGTTAAAGAACCCAGCAGAGTCGGAATTCCGCA
CATTAGCTGAAGTTGATGGTGTCAAAGTTCAAACCCCAATCAACCATCCAACTCTGACTAGTTGGCTGCCAGCGATAGAG
AAATGTGTATTGCGTTACAACACCAGCCACACTGGCATGTTAAAACCGACGGAAGTGATTGCAACAGGCGGGCAAAGCAA
CAACTTGGCTCTCAACTATATTCACCCGCAAGCTTACTCGAGCGAGAATGTAACTCTAAGAATTTACGCAAACCAGTCGG
ATGTACACGACATTTGTAACGGTGGTCAGTAA

Upstream 100 bases:

>100_bases
AAAGAACATAAAAGAAGCCATGATTTGGTGAAGAATTAACAGAACTTCACCTGAGATTTGTCTATTTCGCACCCCAAATC
ATCCAAAATAGAAGAGTTCA

Downstream 100 bases:

>100_bases
CATGAAATTAAAATTATCCATTATTTTACTGGTTATCTCTGCTTTCTTGAGCGGTTGGTTGTACTGGGGTAGCGATGCAA
AAGTAGAGCGCTTGCTTACA

Product: transcription activator ToxR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSNIGTKFILAQRFVFDPNSNSLVDQMSDGEVVRLGSNESRILLMLSERPNEVITRNELHEYVWRDQGFEVDDSSLTQAV
STLRKMLKDSTKSPAFVKTVPKRGYQFIATVERSAPLSSNDQPTTAEIAESDVEPILTFANTTLADEVITETIDPEPTAK
AQENHVKVEPVTNQVKPKDESSNKWLTFGMLLVAFIMPILVLTLKNPAESEFRTLAEVDGVKVQTPINHPTLTSWLPAIE
KCVLRYNTSHTGMLKPTEVIATGGQSNNLALNYIHPQAYSSENVTLRIYANQSDVHDICNGGQ

Sequences:

>Translated_303_residues
MSNIGTKFILAQRFVFDPNSNSLVDQMSDGEVVRLGSNESRILLMLSERPNEVITRNELHEYVWRDQGFEVDDSSLTQAV
STLRKMLKDSTKSPAFVKTVPKRGYQFIATVERSAPLSSNDQPTTAEIAESDVEPILTFANTTLADEVITETIDPEPTAK
AQENHVKVEPVTNQVKPKDESSNKWLTFGMLLVAFIMPILVLTLKNPAESEFRTLAEVDGVKVQTPINHPTLTSWLPAIE
KCVLRYNTSHTGMLKPTEVIATGGQSNNLALNYIHPQAYSSENVTLRIYANQSDVHDICNGGQ
>Mature_302_residues
SNIGTKFILAQRFVFDPNSNSLVDQMSDGEVVRLGSNESRILLMLSERPNEVITRNELHEYVWRDQGFEVDDSSLTQAVS
TLRKMLKDSTKSPAFVKTVPKRGYQFIATVERSAPLSSNDQPTTAEIAESDVEPILTFANTTLADEVITETIDPEPTAKA
QENHVKVEPVTNQVKPKDESSNKWLTFGMLLVAFIMPILVLTLKNPAESEFRTLAEVDGVKVQTPINHPTLTSWLPAIEK
CVLRYNTSHTGMLKPTEVIATGGQSNNLALNYIHPQAYSSENVTLRIYANQSDVHDICNGGQ

Specific function: In the presence of toxS, promotes the expression of the thermostable direct hemolysin 2. May be a global regulator [H]

COG id: COG3710

COG function: function code K; DNA-binding winged-HTH domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 33662; Mature: 33531

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIGTKFILAQRFVFDPNSNSLVDQMSDGEVVRLGSNESRILLMLSERPNEVITRNELH
CCCCCHHHEEEHHEEECCCCCHHHHHCCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHH
EYVWRDQGFEVDDSSLTQAVSTLRKMLKDSTKSPAFVKTVPKRGYQFIATVERSAPLSSN
HHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEEEECCCCCCCC
DQPTTAEIAESDVEPILTFANTTLADEVITETIDPEPTAKAQENHVKVEPVTNQVKPKDE
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCC
SSNKWLTFGMLLVAFIMPILVLTLKNPAESEFRTLAEVDGVKVQTPINHPTLTSWLPAIE
CCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHH
KCVLRYNTSHTGMLKPTEVIATGGQSNNLALNYIHPQAYSSENVTLRIYANQSDVHDICN
HHHHHCCCCCCCCCCCHHHEEECCCCCCEEEEEECCCCCCCCCEEEEEEECCCCHHHHHC
GGQ
CCC
>Mature Secondary Structure 
SNIGTKFILAQRFVFDPNSNSLVDQMSDGEVVRLGSNESRILLMLSERPNEVITRNELH
CCCCHHHEEEHHEEECCCCCHHHHHCCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHH
EYVWRDQGFEVDDSSLTQAVSTLRKMLKDSTKSPAFVKTVPKRGYQFIATVERSAPLSSN
HHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEEEECCCCCCCC
DQPTTAEIAESDVEPILTFANTTLADEVITETIDPEPTAKAQENHVKVEPVTNQVKPKDE
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCC
SSNKWLTFGMLLVAFIMPILVLTLKNPAESEFRTLAEVDGVKVQTPINHPTLTSWLPAIE
CCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHH
KCVLRYNTSHTGMLKPTEVIATGGQSNNLALNYIHPQAYSSENVTLRIYANQSDVHDICN
HHHHHCCCCCCCCCCCHHHEEECCCCCCEEEEEECCCCCCCCCEEEEEEECCCCHHHHHC
GGQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8509337; 10655349; 12620739 [H]