Click here to switch to the map view.

The map label for this gene is znuA [H]

Identifier: 218710205

GI number: 218710205

Start: 2404000

End: 2404884

Strand: Reverse

Name: znuA [H]

Synonym: VS_2237

Alternate gene names: 218710205

Gene position: 2404884-2404000 (Counterclockwise)

Preceding gene: 218710208

Following gene: 218710204

Centisome position: 72.89

GC content: 42.71

Gene sequence:

>885_bases
ATGTCACGTTCATCTTTTATACTTGCTACTTTGCTTTTAGCGCCAAGTGTTGCAAGTGCCAATACTATTCTAACAAGCTT
CAAACCAATTCAAATGATTGTGACAGAATTAACGCAGGGCGTTAGTGAACCTGATGTGTTGATGAACAGCAATGCTTCGC
CGCACGATTATGCGCTTAAGCCATCGGATGTCAAAAAAGTTCATAGTGCCGATATGGTGATCTGGTTTGGCCCTGACCTA
GAAGCTTTTTTGACCAAGGTGATTGGTTCTAAAGAAAACGTTATCAAGATCAGTGAGATTCCGGGGATTAACTTGAGAGA
GTTTGGACATGAAGACCACGATGCTCATGAAGGGCACAACCATGGTAGTCATGACCCGCATTTTTGGTTGGGTATCGATC
AAGTCGAGGTCGCGGCAAAATATATCTCAGCTAAGCTAATTGAGTCAGACTCTGATAACGCCATGGCGTATCAAGAGAAT
CTAGATTCATTCTTGATTGCTTTGAAAGAGAAACAGCAGGCGATTCATGAACAACTCGCGCCAGTGAAAGACAAAGGCTA
CTACGTATTCCATGACGCGTATGGCTACTTCGAACAAGAATTTAAGTTGAATAATCTAGGTCACTTTACGGTTAGCCCTG
AGCGTAAACCTGGCGCAAAAAGTCTGATAGCTATCAAGAAGACTTTGGTGCGTGAAAATGTTCAATGCGTATTTTCAGAG
CCTCAATTTACACCAGCGGTGATTGAATCGGTGACTCGTGGAAGTAACGCTAAACAAGGACAACTTGATCCTGTCGGTTC
GCAGGTTGAAGTGAAGAGTGGAAGCTATTTTGATTTTCTTCAGCAGCTTACAGATAGTTACACAAGTTGCTTGAGTGGAA
TGTAA

Upstream 100 bases:

>100_bases
TGGATTAAATTATCCATGAATAGAACTCATTTGCAATTCGCTAATGTTATAATGTAACATTTACCTCAAGCCTAAGCTAC
TTTTCTATTAACGAGGAATT

Downstream 100 bases:

>100_bases
TCAATATCGAGTATTCTTTACGACACTTTGTTCTCGTTAATTGATGAATCATGCCGCTTTTTGCGGCATTTTCGTGACCG
CTAAGATAAAACCTTCCAAC

Product: high-affinity zinc uptake system protein ZnuA

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSRSSFILATLLLAPSVASANTILTSFKPIQMIVTELTQGVSEPDVLMNSNASPHDYALKPSDVKKVHSADMVIWFGPDL
EAFLTKVIGSKENVIKISEIPGINLREFGHEDHDAHEGHNHGSHDPHFWLGIDQVEVAAKYISAKLIESDSDNAMAYQEN
LDSFLIALKEKQQAIHEQLAPVKDKGYYVFHDAYGYFEQEFKLNNLGHFTVSPERKPGAKSLIAIKKTLVRENVQCVFSE
PQFTPAVIESVTRGSNAKQGQLDPVGSQVEVKSGSYFDFLQQLTDSYTSCLSGM

Sequences:

>Translated_294_residues
MSRSSFILATLLLAPSVASANTILTSFKPIQMIVTELTQGVSEPDVLMNSNASPHDYALKPSDVKKVHSADMVIWFGPDL
EAFLTKVIGSKENVIKISEIPGINLREFGHEDHDAHEGHNHGSHDPHFWLGIDQVEVAAKYISAKLIESDSDNAMAYQEN
LDSFLIALKEKQQAIHEQLAPVKDKGYYVFHDAYGYFEQEFKLNNLGHFTVSPERKPGAKSLIAIKKTLVRENVQCVFSE
PQFTPAVIESVTRGSNAKQGQLDPVGSQVEVKSGSYFDFLQQLTDSYTSCLSGM
>Mature_293_residues
SRSSFILATLLLAPSVASANTILTSFKPIQMIVTELTQGVSEPDVLMNSNASPHDYALKPSDVKKVHSADMVIWFGPDLE
AFLTKVIGSKENVIKISEIPGINLREFGHEDHDAHEGHNHGSHDPHFWLGIDQVEVAAKYISAKLIESDSDNAMAYQENL
DSFLIALKEKQQAIHEQLAPVKDKGYYVFHDAYGYFEQEFKLNNLGHFTVSPERKPGAKSLIAIKKTLVRENVQCVFSEP
QFTPAVIESVTRGSNAKQGQLDPVGSQVEVKSGSYFDFLQQLTDSYTSCLSGM

Specific function: Involved in the high-affinity zinc uptake transport system [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=289, Percent_Identity=41.1764705882353, Blast_Score=238, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 32559; Mature: 32428

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSSFILATLLLAPSVASANTILTSFKPIQMIVTELTQGVSEPDVLMNSNASPHDYALK
CCCCHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCC
PSDVKKVHSADMVIWFGPDLEAFLTKVIGSKENVIKISEIPGINLREFGHEDHDAHEGHN
CHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCCCCCCCCCCC
HGSHDPHFWLGIDQVEVAAKYISAKLIESDSDNAMAYQENLDSFLIALKEKQQAIHEQLA
CCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PVKDKGYYVFHDAYGYFEQEFKLNNLGHFTVSPERKPGAKSLIAIKKTLVRENVQCVFSE
CCCCCCEEEEECCCCHHHHHEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECC
PQFTPAVIESVTRGSNAKQGQLDPVGSQVEVKSGSYFDFLQQLTDSYTSCLSGM
CCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRSSFILATLLLAPSVASANTILTSFKPIQMIVTELTQGVSEPDVLMNSNASPHDYALK
CCCHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCC
PSDVKKVHSADMVIWFGPDLEAFLTKVIGSKENVIKISEIPGINLREFGHEDHDAHEGHN
CHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCCCCCCCCCCC
HGSHDPHFWLGIDQVEVAAKYISAKLIESDSDNAMAYQENLDSFLIALKEKQQAIHEQLA
CCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PVKDKGYYVFHDAYGYFEQEFKLNNLGHFTVSPERKPGAKSLIAIKKTLVRENVQCVFSE
CCCCCCEEEEECCCCHHHHHEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECC
PQFTPAVIESVTRGSNAKQGQLDPVGSQVEVKSGSYFDFLQQLTDSYTSCLSGM
CCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 9600841; 9680209 [H]