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The map label for this gene is argS [H]

Identifier: 218710198

GI number: 218710198

Start: 2394450

End: 2396183

Strand: Direct

Name: argS [H]

Synonym: VS_2230

Alternate gene names: 218710198

Gene position: 2394450-2396183 (Clockwise)

Preceding gene: 218710196

Following gene: 218710199

Centisome position: 72.57

GC content: 46.31

Gene sequence:

>1734_bases
GTGAATATCCAAGCACTGATTAATGACAAAGTATCTCAGGCTCTAGAAGCCGCTGGCGCACCTGCAGGCTCTCCTGCGGC
TGTCCGTCAATCTGCAAAACCACAATTTGGTGACTACCAAGCAAACGGCATTATGGGTGTTGCTAAACGACTAGGCACTA
ACCCTCGAGAATTTGCTCAAAAAGTATTGGACGTTCTAAACCTAGACGGTATCGCTTCTAAAGTTGAAATCGCAGGTCCA
GGTTTCCTAAACATCTTCCTAGATGAAACGTTCCTGGCACAACAAGCAGACGCAGCGCTTGCTGACTCTCGCCTTGGTGT
TTCAGCCGCAGAAGCACAAACGATTGTTGCTGACTACTCAGCTCCAAACGTTGCAAAAGAAATGCACGTAGGCCACTTAC
GTTCAACGATCATCGGTGATGCTGTTGTTCGTACACTTGAGTTCTTAGGTCACAAAGTTATCCGTGCTAACCACATTGGT
GACTGGGGTACTCAATTCGGTATGCTTATCGCAAACCTTGAGCGCATCCAAGCTGAAACTGGTGAAGTTTCAATGGAACT
TTCAGATCTTGAACAGTTCTACCGTGAATCTAAAAAGCTTTACGACGAAGACGAAGAATTCGCAGTGAAAGCTCGTGGCT
ACGTAGTGAAACTGCAAGGTGGCGACGCATACTGTGCTGAAATGTGGAAAAAGCTGGTTGACGTAACCATGGTTCAAAAC
CAACGTAACTACGATCGCCTGAACGTATCACTGACACGTGATGATGTGATGGGTGAAAGTATGTACAACCATATGCTTTC
AAACATCGTTTCTGACCTACAAACACAAGGTCTAGCAAAAGAGTCTGACGGCGCACAAGTTGTATTCCTAGACGAATACA
AAAACAAAGATGGCGACCCTATGGGCGTTATCGTGCAAAAACGTGACGGTGGCTTCCTATACACCACCACCGATATTGCA
TGTGCTAAATATCGTTTTGAAGAACTGGGCGCAGATCGCGTACTTTACTTCATCGACTCTCGTCAGCACCAACACCTAAT
GCAAGCTTGGACTATCGTTCGTAAAGCGGGTTATGTTCCTGAGTCTGTATCTCTTGAGCACCACGCGTTCGGCATGATGC
TAGGTAAAGATGGTAAGCCATTTAAAACTCGTGCTGGCGGTACAGTGCGTCTTGCTGACCTTCTGGACGAAGCAGAAGTA
CGTGCAACTCAGCTGATTGAATCTAAAAACCCTGAGCTAGCAGAAGACGAGAAGAAAACCATTGCGAACACAGTAGCAAT
GGCAGCAGTTAAATACGCAGACCTTTCTAAGCACCGTACCACTGATTACGTGTTCGACTGGGAAAACATGCTGGCATTTG
AAGGCAACACAGCACCGTACATGCAGTACGCATACACTCGTGTCGCTTCAATCTTTGCTAAAGCAGGCATTTCTATGGAC
TCTCTTGAAGGTGAAATCAAAATCACTGAAGAAAAAGAGAAAGCCCTTATCGCGAAACTTCTACAATTTGAAGAAGCGGT
ACAGTCTGTTGCTCGTGAAGGTCAACCACACATCATGTGTAGCTACCTGTTCGAACTTGCTGGTCAATTCTCTAGCTTCT
ACGAAGCGTGCCCTATCCTTGTGGCTGAAGATGAAACCGTTAAACAGAGCCGCCTGAAGCTTGCTGCACTGACAGCTAAG
ACTATCAAGCAAGGCCTGTCGCTTCTAGGTATCGAAACTCTAGAGCGCATGTAA

Upstream 100 bases:

>100_bases
ATTTCAGCATTAAATCGTTAACTAGAAGCATAATTAGCCAAATTTAATGCCCACGAAATAACGGCTACTCTTATTCATCC
TTGAATTGAAGGAAACGCGT

Downstream 100 bases:

>100_bases
TGCCCTTCTGGTTACAATGAATAAATACAAAGGTTGATGTGAGAGCATCAACCTTTTGTTTTATCTAACGTATACTGATA
CCAATCGTAGTAAATAACTA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNIQALINDKVSQALEAAGAPAGSPAAVRQSAKPQFGDYQANGIMGVAKRLGTNPREFAQKVLDVLNLDGIASKVEIAGP
GFLNIFLDETFLAQQADAALADSRLGVSAAEAQTIVADYSAPNVAKEMHVGHLRSTIIGDAVVRTLEFLGHKVIRANHIG
DWGTQFGMLIANLERIQAETGEVSMELSDLEQFYRESKKLYDEDEEFAVKARGYVVKLQGGDAYCAEMWKKLVDVTMVQN
QRNYDRLNVSLTRDDVMGESMYNHMLSNIVSDLQTQGLAKESDGAQVVFLDEYKNKDGDPMGVIVQKRDGGFLYTTTDIA
CAKYRFEELGADRVLYFIDSRQHQHLMQAWTIVRKAGYVPESVSLEHHAFGMMLGKDGKPFKTRAGGTVRLADLLDEAEV
RATQLIESKNPELAEDEKKTIANTVAMAAVKYADLSKHRTTDYVFDWENMLAFEGNTAPYMQYAYTRVASIFAKAGISMD
SLEGEIKITEEKEKALIAKLLQFEEAVQSVAREGQPHIMCSYLFELAGQFSSFYEACPILVAEDETVKQSRLKLAALTAK
TIKQGLSLLGIETLERM

Sequences:

>Translated_577_residues
MNIQALINDKVSQALEAAGAPAGSPAAVRQSAKPQFGDYQANGIMGVAKRLGTNPREFAQKVLDVLNLDGIASKVEIAGP
GFLNIFLDETFLAQQADAALADSRLGVSAAEAQTIVADYSAPNVAKEMHVGHLRSTIIGDAVVRTLEFLGHKVIRANHIG
DWGTQFGMLIANLERIQAETGEVSMELSDLEQFYRESKKLYDEDEEFAVKARGYVVKLQGGDAYCAEMWKKLVDVTMVQN
QRNYDRLNVSLTRDDVMGESMYNHMLSNIVSDLQTQGLAKESDGAQVVFLDEYKNKDGDPMGVIVQKRDGGFLYTTTDIA
CAKYRFEELGADRVLYFIDSRQHQHLMQAWTIVRKAGYVPESVSLEHHAFGMMLGKDGKPFKTRAGGTVRLADLLDEAEV
RATQLIESKNPELAEDEKKTIANTVAMAAVKYADLSKHRTTDYVFDWENMLAFEGNTAPYMQYAYTRVASIFAKAGISMD
SLEGEIKITEEKEKALIAKLLQFEEAVQSVAREGQPHIMCSYLFELAGQFSSFYEACPILVAEDETVKQSRLKLAALTAK
TIKQGLSLLGIETLERM
>Mature_577_residues
MNIQALINDKVSQALEAAGAPAGSPAAVRQSAKPQFGDYQANGIMGVAKRLGTNPREFAQKVLDVLNLDGIASKVEIAGP
GFLNIFLDETFLAQQADAALADSRLGVSAAEAQTIVADYSAPNVAKEMHVGHLRSTIIGDAVVRTLEFLGHKVIRANHIG
DWGTQFGMLIANLERIQAETGEVSMELSDLEQFYRESKKLYDEDEEFAVKARGYVVKLQGGDAYCAEMWKKLVDVTMVQN
QRNYDRLNVSLTRDDVMGESMYNHMLSNIVSDLQTQGLAKESDGAQVVFLDEYKNKDGDPMGVIVQKRDGGFLYTTTDIA
CAKYRFEELGADRVLYFIDSRQHQHLMQAWTIVRKAGYVPESVSLEHHAFGMMLGKDGKPFKTRAGGTVRLADLLDEAEV
RATQLIESKNPELAEDEKKTIANTVAMAAVKYADLSKHRTTDYVFDWENMLAFEGNTAPYMQYAYTRVASIFAKAGISMD
SLEGEIKITEEKEKALIAKLLQFEEAVQSVAREGQPHIMCSYLFELAGQFSSFYEACPILVAEDETVKQSRLKLAALTAK
TIKQGLSLLGIETLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=596, Percent_Identity=37.5838926174497, Blast_Score=394, Evalue=1e-109,
Organism=Homo sapiens, GI197100773, Length=472, Percent_Identity=30.7203389830508, Blast_Score=211, Evalue=1e-54,
Organism=Escherichia coli, GI1788184, Length=579, Percent_Identity=72.5388601036269, Blast_Score=867, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=585, Percent_Identity=39.1452991452991, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71985068, Length=545, Percent_Identity=40.1834862385321, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17532153, Length=492, Percent_Identity=27.6422764227642, Blast_Score=155, Evalue=8e-38,
Organism=Saccharomyces cerevisiae, GI6320548, Length=543, Percent_Identity=31.4917127071823, Blast_Score=252, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6321883, Length=527, Percent_Identity=29.6015180265655, Blast_Score=231, Evalue=3e-61,
Organism=Drosophila melanogaster, GI18859963, Length=580, Percent_Identity=38.2758620689655, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI28571570, Length=488, Percent_Identity=29.7131147540984, Blast_Score=184, Evalue=1e-46,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 63843; Mature: 63843

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQALINDKVSQALEAAGAPAGSPAAVRQSAKPQFGDYQANGIMGVAKRLGTNPREFAQ
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHH
KVLDVLNLDGIASKVEIAGPGFLNIFLDETFLAQQADAALADSRLGVSAAEAQTIVADYS
HHHHHHCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCCCHHHHHEEEEECC
APNVAKEMHVGHLRSTIIGDAVVRTLEFLGHKVIRANHIGDWGTQFGMLIANLERIQAET
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHHCC
GEVSMELSDLEQFYRESKKLYDEDEEFAVKARGYVVKLQGGDAYCAEMWKKLVDVTMVQN
CCEEEEHHHHHHHHHHHHHHCCCCHHHEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHC
QRNYDRLNVSLTRDDVMGESMYNHMLSNIVSDLQTQGLAKESDGAQVVFLDEYKNKDGDP
CCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCC
MGVIVQKRDGGFLYTTTDIACAKYRFEELGADRVLYFIDSRQHQHLMQAWTIVRKAGYVP
EEEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
ESVSLEHHAFGMMLGKDGKPFKTRAGGTVRLADLLDEAEVRATQLIESKNPELAEDEKKT
CCCCCCHHHHEEEECCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
IANTVAMAAVKYADLSKHRTTDYVFDWENMLAFEGNTAPYMQYAYTRVASIFAKAGISMD
HHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHH
SLEGEIKITEEKEKALIAKLLQFEEAVQSVAREGQPHIMCSYLFELAGQFSSFYEACPIL
CCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEE
VAEDETVKQSRLKLAALTAKTIKQGLSLLGIETLERM
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIQALINDKVSQALEAAGAPAGSPAAVRQSAKPQFGDYQANGIMGVAKRLGTNPREFAQ
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHH
KVLDVLNLDGIASKVEIAGPGFLNIFLDETFLAQQADAALADSRLGVSAAEAQTIVADYS
HHHHHHCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCCCHHHHHEEEEECC
APNVAKEMHVGHLRSTIIGDAVVRTLEFLGHKVIRANHIGDWGTQFGMLIANLERIQAET
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHHCC
GEVSMELSDLEQFYRESKKLYDEDEEFAVKARGYVVKLQGGDAYCAEMWKKLVDVTMVQN
CCEEEEHHHHHHHHHHHHHHCCCCHHHEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHC
QRNYDRLNVSLTRDDVMGESMYNHMLSNIVSDLQTQGLAKESDGAQVVFLDEYKNKDGDP
CCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCC
MGVIVQKRDGGFLYTTTDIACAKYRFEELGADRVLYFIDSRQHQHLMQAWTIVRKAGYVP
EEEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
ESVSLEHHAFGMMLGKDGKPFKTRAGGTVRLADLLDEAEVRATQLIESKNPELAEDEKKT
CCCCCCHHHHEEEECCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
IANTVAMAAVKYADLSKHRTTDYVFDWENMLAFEGNTAPYMQYAYTRVASIFAKAGISMD
HHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHH
SLEGEIKITEEKEKALIAKLLQFEEAVQSVAREGQPHIMCSYLFELAGQFSSFYEACPIL
CCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEE
VAEDETVKQSRLKLAALTAKTIKQGLSLLGIETLERM
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA