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The map label for this gene is clpX [H]

Identifier: 218710173

GI number: 218710173

Start: 2353497

End: 2354777

Strand: Reverse

Name: clpX [H]

Synonym: VS_2204

Alternate gene names: 218710173

Gene position: 2354777-2353497 (Counterclockwise)

Preceding gene: 218710174

Following gene: 218710172

Centisome position: 71.37

GC content: 43.72

Gene sequence:

>1281_bases
ATGACAGATAAAAGCAAAGAGGGTGGTAGCGGTAAATTGCTTTACTGCTCTTTCTGTGGCAAAAGCCAGCACGAAGTTCG
CAAGTTAATCGCAGGTCCTTCTGTTTACATTTGTGATGAATGTGTCGATCTTTGTAACGACATTATTCGTGAAGAAATTA
AAGATGTTCTTCCAAAGAAAGAATCGGAATCGCTGCCAACGCCGCGTGAGATTCGTGAGCATCTTGACGACTATGTAATC
GGTCAAGAATACGCGAAAAAAGTGCTAGCAGTTGCAGTATATAACCACTACAAGCGTTTACGTAATGGTGATACGACGGC
TGAAGGCGTAGAGCTAGGTAAGAGTAACATTCTTCTTATCGGTCCTACTGGTAGTGGTAAAACACTACTGGCTGAAACAC
TGGCTCGTTTCCTAGACGTTCCTTTCACAATGGCAGATGCAACAACACTAACCGAAGCGGGTTATGTGGGCGAAGATGTT
GAAAACATCATCCAGAAGTTGCTTCAGAAATGTGATTACGACGTAGCGAAAGCGGAACGCGGCATTGTTTACATCGATGA
AATCGATAAGATTTCTCGTAAAGCTGAAAACCCATCGATCACGCGTGACGTGTCTGGTGAAGGTGTACAGCAAGCTCTAT
TAAAACTTGTTGAAGGTACAGTGGCTTCAGTTCCACCTCAAGGTGGTCGTAAGCATCCACAGCAAGAGTTCTTGCAAGTG
GACACGTCTAAGATCCTATTTATCTGTGGTGGTGCGTTTGCCGGCCTAGATAAAGTGATTGAGCAACGTGTAGAAACAGG
TTCAGGTATCGGCTTTGGCGCAGAAGTGCGTTCAAAAGACGAAACCAAAACTATCGGTGAACTGTTCACTCAAGTAGAAC
CTGAAGATCTAGTGAAGTATGGTTTGATTCCAGAATTCATTGGTCGTCTACCTGTTACAACAACACTGACAGAGCTTGAT
GAAGAAGCGCTAATCCAAATCCTTTGTGAGCCAAAGAATGCACTGACAAAACAGTACGCTGCATTATTTGAACTTGAGGA
TACAGAGTTAGAATTCCGTGAAGATGCCCTACGCGCAATTGCGAAGAAAGCAATGAACCGTAAAACGGGTGCTCGTGGTC
TACGCTCTATCTTGGAAGGTGTTCTACTAGAAACTATGTACGAACTGCCATCTTCAACTGATGTAAGCAAGGTTGTGATT
GATGAGTCGGTAATTAATGGTGAGTCAGAACCACTATTGATTTACAGTAACTCAGATAACCAAGCAGCTGTTGCAGAGTA
G

Upstream 100 bases:

>100_bases
TAATCACCGCGGTCAATAATTGCAGGGCAATTGTTTAACGCAAAGTGATTCAAATTGATATACACTCAAACATAGAGAGT
AAAGGCTAAGAGGTTAGCGA

Downstream 100 bases:

>100_bases
GTCTTTTTAAGACTACACACTCAAATTGAAAAAGGAGGTAAGCAATTACCTCCTTTTTTTTATTCTTCCATTGAATCCAG
TCGTTTAAGCCCCATATACT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTDKSKEGGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKKESESLPTPREIREHLDDYVI
GQEYAKKVLAVAVYNHYKRLRNGDTTAEGVELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVAKAERGIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLVEGTVASVPPQGGRKHPQQEFLQV
DTSKILFICGGAFAGLDKVIEQRVETGSGIGFGAEVRSKDETKTIGELFTQVEPEDLVKYGLIPEFIGRLPVTTTLTELD
EEALIQILCEPKNALTKQYAALFELEDTELEFREDALRAIAKKAMNRKTGARGLRSILEGVLLETMYELPSSTDVSKVVI
DESVINGESEPLLIYSNSDNQAAVAE

Sequences:

>Translated_426_residues
MTDKSKEGGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKKESESLPTPREIREHLDDYVI
GQEYAKKVLAVAVYNHYKRLRNGDTTAEGVELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVAKAERGIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLVEGTVASVPPQGGRKHPQQEFLQV
DTSKILFICGGAFAGLDKVIEQRVETGSGIGFGAEVRSKDETKTIGELFTQVEPEDLVKYGLIPEFIGRLPVTTTLTELD
EEALIQILCEPKNALTKQYAALFELEDTELEFREDALRAIAKKAMNRKTGARGLRSILEGVLLETMYELPSSTDVSKVVI
DESVINGESEPLLIYSNSDNQAAVAE
>Mature_425_residues
TDKSKEGGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKKESESLPTPREIREHLDDYVIG
QEYAKKVLAVAVYNHYKRLRNGDTTAEGVELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVAKAERGIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLVEGTVASVPPQGGRKHPQQEFLQVD
TSKILFICGGAFAGLDKVIEQRVETGSGIGFGAEVRSKDETKTIGELFTQVEPEDLVKYGLIPEFIGRLPVTTTLTELDE
EALIQILCEPKNALTKQYAALFELEDTELEFREDALRAIAKKAMNRKTGARGLRSILEGVLLETMYELPSSTDVSKVVID
ESVINGESEPLLIYSNSDNQAAVAE

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=330, Percent_Identity=50.9090909090909, Blast_Score=312, Evalue=3e-85,
Organism=Escherichia coli, GI1786642, Length=426, Percent_Identity=83.3333333333333, Blast_Score=717, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=130, Percent_Identity=39.2307692307692, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=315, Percent_Identity=46.031746031746, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=315, Percent_Identity=46.031746031746, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=410, Percent_Identity=38.5365853658537, Blast_Score=248, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI71988660, Length=258, Percent_Identity=39.5348837209302, Blast_Score=174, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=437, Percent_Identity=38.6727688787185, Blast_Score=275, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24648291, Length=336, Percent_Identity=45.5357142857143, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24648289, Length=336, Percent_Identity=45.5357142857143, Blast_Score=283, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46812; Mature: 46681

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKSKEGGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKK
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCC
ESESLPTPREIREHLDDYVIGQEYAKKVLAVAVYNHYKRLRNGDTTAEGVELGKSNILLI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEE
GPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVAKAER
ECCCCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCC
GIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLVEGTVASVPPQGGRKHPQQEFLQV
CEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHH
DTSKILFICGGAFAGLDKVIEQRVETGSGIGFGAEVRSKDETKTIGELFTQVEPEDLVKY
CCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
GLIPEFIGRLPVTTTLTELDEEALIQILCEPKNALTKQYAALFELEDTELEFREDALRAI
CCCHHHHCCCCCHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AKKAMNRKTGARGLRSILEGVLLETMYELPSSTDVSKVVIDESVINGESEPLLIYSNSDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCC
QAAVAE
CCCCCC
>Mature Secondary Structure 
TDKSKEGGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKK
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCC
ESESLPTPREIREHLDDYVIGQEYAKKVLAVAVYNHYKRLRNGDTTAEGVELGKSNILLI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEE
GPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVAKAER
ECCCCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCC
GIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLVEGTVASVPPQGGRKHPQQEFLQV
CEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHH
DTSKILFICGGAFAGLDKVIEQRVETGSGIGFGAEVRSKDETKTIGELFTQVEPEDLVKY
CCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
GLIPEFIGRLPVTTTLTELDEEALIQILCEPKNALTKQYAALFELEDTELEFREDALRAI
CCCHHHHCCCCCHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AKKAMNRKTGARGLRSILEGVLLETMYELPSSTDVSKVVIDESVINGESEPLLIYSNSDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCC
QAAVAE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA