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The map label for this gene is udp [H]

Identifier: 218710062

GI number: 218710062

Start: 2236027

End: 2236785

Strand: Reverse

Name: udp [H]

Synonym: VS_2082

Alternate gene names: 218710062

Gene position: 2236785-2236027 (Counterclockwise)

Preceding gene: 218710063

Following gene: 218710059

Centisome position: 67.8

GC content: 47.3

Gene sequence:

>759_bases
ATGTCTCAAGCTGTTTTCCACTTAGGTGTTACTGAAGCAGATCTTAACGGTGCTACTCTTGCGATCATTCCTGGTGATCC
TGCTCGTGTGCAAAAAATTGCAGAAGAGATGGAGAATCCCGTATTTCTTGCGAGTCACCGTGAATACACGCTTTACCGCG
CAGAGCTAGACGGTAAGTCAGTTGTTGTATGTTCAACAGGTATCGGCGGCCCATCTACTTCTATCGCCGTTGAAGAGCTT
GCTCAGCTTGGTGTTCGTACTTTCCTACGTGTTGGGACGACTGGTGCGATCCAACCTCACGTAAACGTGGGTGACATGAT
TGTTTCTACGGGTTCTGTTCGTCTAGACGGCGCTAGCCTGCACTTCGCTCCTATGGAGTTTCCAGCAGTTGCTGACTTCG
AAGTTGCTACAGCAATGAAAGCAGCAGTTGAAGAATCAGGTGCAGCAGTTCACATGGGCGTAACCGCTTCAAGTGATACT
TTCTACCCAGGTCAAGAGCGTTACGACACGTTCTCTGGTCGCGTGGTTAAGCGTTTCCAAGGTTCTATGCAAGAATGGCA
AGACATGGGTGTTCTTAACTTCGAAATGGAATCTGGAACGCTACTAACAATGTGTGCAAGTTCTGGTTTGAAAGCAGGTT
GTGTTGCTGGTGTGATCATCAACCGTACTCAAAAAGAGATACCTGATCACGAGACACTAAAAGTAACGGAAGCGCGCTCA
ATCAAAGTGGTTGTAGAAGCTGCTCGTAAAATGCTTTAA

Upstream 100 bases:

>100_bases
TCATTTCATTATGAGCTTGGTTAGAGTGTGTTCGTACCCCACGAATTTACTATGAGCTTAAATAAGGGTAAAAAGCCCAA
TAAGCCAAAAGGAGCGAACT

Downstream 100 bases:

>100_bases
GTCGGTAACAGTACTTTTAGTTTTCAAGTGCTTTAAGTCTTAAAACGACTTCAAATTTTGAAAATGGCCACATCGAATGA
TGTGGCCATTTTTTTGCGTG

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSQAVFHLGVTEADLNGATLAIIPGDPARVQKIAEEMENPVFLASHREYTLYRAELDGKSVVVCSTGIGGPSTSIAVEEL
AQLGVRTFLRVGTTGAIQPHVNVGDMIVSTGSVRLDGASLHFAPMEFPAVADFEVATAMKAAVEESGAAVHMGVTASSDT
FYPGQERYDTFSGRVVKRFQGSMQEWQDMGVLNFEMESGTLLTMCASSGLKAGCVAGVIINRTQKEIPDHETLKVTEARS
IKVVVEAARKML

Sequences:

>Translated_252_residues
MSQAVFHLGVTEADLNGATLAIIPGDPARVQKIAEEMENPVFLASHREYTLYRAELDGKSVVVCSTGIGGPSTSIAVEEL
AQLGVRTFLRVGTTGAIQPHVNVGDMIVSTGSVRLDGASLHFAPMEFPAVADFEVATAMKAAVEESGAAVHMGVTASSDT
FYPGQERYDTFSGRVVKRFQGSMQEWQDMGVLNFEMESGTLLTMCASSGLKAGCVAGVIINRTQKEIPDHETLKVTEARS
IKVVVEAARKML
>Mature_251_residues
SQAVFHLGVTEADLNGATLAIIPGDPARVQKIAEEMENPVFLASHREYTLYRAELDGKSVVVCSTGIGGPSTSIAVEELA
QLGVRTFLRVGTTGAIQPHVNVGDMIVSTGSVRLDGASLHFAPMEFPAVADFEVATAMKAAVEESGAAVHMGVTASSDTF
YPGQERYDTFSGRVVKRFQGSMQEWQDMGVLNFEMESGTLLTMCASSGLKAGCVAGVIINRTQKEIPDHETLKVTEARSI
KVVVEAARKML

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=248, Percent_Identity=75, Blast_Score=403, Evalue=1e-114,
Organism=Escherichia coli, GI1790844, Length=244, Percent_Identity=29.0983606557377, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 26897; Mature: 26766

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAVFHLGVTEADLNGATLAIIPGDPARVQKIAEEMENPVFLASHREYTLYRAELDGKS
CCCEEEEECCEEECCCCEEEEEECCCHHHHHHHHHHHCCCEEEECCCEEEEEEEECCCCE
VVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVSTGSVRLDGASL
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCEEECCCEE
HFAPMEFPAVADFEVATAMKAAVEESGAAVHMGVTASSDTFYPGQERYDTFSGRVVKRFQ
EECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHCCHHHHHHH
GSMQEWQDMGVLNFEMESGTLLTMCASSGLKAGCVAGVIINRTQKEIPDHETLKVTEARS
HHHHHHHHCCEEEEEECCCCEEEEECCCCCCCHHHHHHEECCHHHHCCCCCEEEEECCCH
IKVVVEAARKML
HHHHHHHHHHCC
>Mature Secondary Structure 
SQAVFHLGVTEADLNGATLAIIPGDPARVQKIAEEMENPVFLASHREYTLYRAELDGKS
CCEEEEECCEEECCCCEEEEEECCCHHHHHHHHHHHCCCEEEECCCEEEEEEEECCCCE
VVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVSTGSVRLDGASL
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCEEECCCEE
HFAPMEFPAVADFEVATAMKAAVEESGAAVHMGVTASSDTFYPGQERYDTFSGRVVKRFQ
EECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHCCHHHHHHH
GSMQEWQDMGVLNFEMESGTLLTMCASSGLKAGCVAGVIINRTQKEIPDHETLKVTEARS
HHHHHHHHCCEEEEEECCCCEEEEECCCCCCCHHHHHHEECCHHHHCCCCCEEEEECCCH
IKVVVEAARKML
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2674901; 1379743; 9278503; 8506346; 8899705; 9661793; 7796917; 12499542 [H]