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The map label for this gene is kdsB [H]

Identifier: 218710039

GI number: 218710039

Start: 2209258

End: 2210004

Strand: Reverse

Name: kdsB [H]

Synonym: VS_2059

Alternate gene names: 218710039

Gene position: 2210004-2209258 (Counterclockwise)

Preceding gene: 218710040

Following gene: 218710038

Centisome position: 66.98

GC content: 47.26

Gene sequence:

>747_bases
ATGTCTTATACGGTTGTTATACCTGCAAGATACCAATCGAGCCGTTTACCAGGGAAGCCACTTGCTGACATTGGTGGAAA
GCCGATGATTCAATGGGTATACGAACAGTCAATGAAGGCGGGTGCCGATAACGTTATTATCGCTACCGACGACGCTCGAG
TTGAAAAAGCGGCCAAAGCATTTGGCGCGACCGTTTGTATGACATCACCGAATCATGAGTCAGGCACTGAGCGCCTCGCT
GAAGTGATTGAAGTTATGAAGATTCCAGATGATCATATTATCGTGAATGTTCAAGGTGATGAGCCACTTATCCCACCTGC
GATCATTAATCAGGTCGCGAACAACCTTGCGAACAGTACAGCTCCGATGGCAACACTCGGTGTGGAAATTACTCATGCTG
ACGAAGTGTTTAATCCTAACGCCGTAAAAGTTGTGACCGACAAAGATGGGTATGCCCTGTACTTTAGCCGAGCTACTATT
CCTTGGGATCGCGATGCTTACGCGAACAATGGTACAGCTGCTGAATCTCCACTGCTTCGTCACATTGGCATTTACGCTTA
CCGTGCGGGTTTTATTAATACCTATATCAATTGGGAACCAAGTACCCTTGAGCGTATTGAGTGCCTAGAGCAGCTACGTG
TACTTTGGTACGGTGAAAAAATCCATGTAGACGTTGCGGCAGAAGCACCTGCAGCTGGTGTTGATACGCCAGAAGACCTA
GAAGCGGTTCGAGCTATTATTGGCTAA

Upstream 100 bases:

>100_bases
TTGTTTGTAAAATTGATCGCCTTGCTTACCCAATTAAAGAGGGTATTCCTGTTCTTTTGGAACCTGAAGCTCGCACCGTT
TCAATGGATGAGGGTAAGTA

Downstream 100 bases:

>100_bases
GCGTCTTTTAGCGACTACTTCTTTGCTCTACAAAAATGCAAAATCATGAGCCTTGCTTATCGCGAGGCTTTTTTATGCCT
AAAGAGAAGCGGATGACAGC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSYTVVIPARYQSSRLPGKPLADIGGKPMIQWVYEQSMKAGADNVIIATDDARVEKAAKAFGATVCMTSPNHESGTERLA
EVIEVMKIPDDHIIVNVQGDEPLIPPAIINQVANNLANSTAPMATLGVEITHADEVFNPNAVKVVTDKDGYALYFSRATI
PWDRDAYANNGTAAESPLLRHIGIYAYRAGFINTYINWEPSTLERIECLEQLRVLWYGEKIHVDVAAEAPAAGVDTPEDL
EAVRAIIG

Sequences:

>Translated_248_residues
MSYTVVIPARYQSSRLPGKPLADIGGKPMIQWVYEQSMKAGADNVIIATDDARVEKAAKAFGATVCMTSPNHESGTERLA
EVIEVMKIPDDHIIVNVQGDEPLIPPAIINQVANNLANSTAPMATLGVEITHADEVFNPNAVKVVTDKDGYALYFSRATI
PWDRDAYANNGTAAESPLLRHIGIYAYRAGFINTYINWEPSTLERIECLEQLRVLWYGEKIHVDVAAEAPAAGVDTPEDL
EAVRAIIG
>Mature_247_residues
SYTVVIPARYQSSRLPGKPLADIGGKPMIQWVYEQSMKAGADNVIIATDDARVEKAAKAFGATVCMTSPNHESGTERLAE
VIEVMKIPDDHIIVNVQGDEPLIPPAIINQVANNLANSTAPMATLGVEITHADEVFNPNAVKVVTDKDGYALYFSRATIP
WDRDAYANNGTAAESPLLRHIGIYAYRAGFINTYINWEPSTLERIECLEQLRVLWYGEKIHVDVAAEAPAAGVDTPEDLE
AVRAIIG

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=245, Percent_Identity=64.4897959183673, Blast_Score=327, Evalue=5e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27034; Mature: 26903

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTVVIPARYQSSRLPGKPLADIGGKPMIQWVYEQSMKAGADNVIIATDDARVEKAAKA
CCEEEEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHH
FGATVCMTSPNHESGTERLAEVIEVMKIPDDHIIVNVQGDEPLIPPAIINQVANNLANST
HCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCC
APMATLGVEITHADEVFNPNAVKVVTDKDGYALYFSRATIPWDRDAYANNGTAAESPLLR
CCEEEEEEEEEEHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHH
HIGIYAYRAGFINTYINWEPSTLERIECLEQLRVLWYGEKIHVDVAAEAPAAGVDTPEDL
HHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHEECCEEEEEEECCCCCCCCCCHHHH
EAVRAIIG
HHHHHHHC
>Mature Secondary Structure 
SYTVVIPARYQSSRLPGKPLADIGGKPMIQWVYEQSMKAGADNVIIATDDARVEKAAKA
CEEEEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHH
FGATVCMTSPNHESGTERLAEVIEVMKIPDDHIIVNVQGDEPLIPPAIINQVANNLANST
HCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCC
APMATLGVEITHADEVFNPNAVKVVTDKDGYALYFSRATIPWDRDAYANNGTAAESPLLR
CCEEEEEEEEEEHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHH
HIGIYAYRAGFINTYINWEPSTLERIECLEQLRVLWYGEKIHVDVAAEAPAAGVDTPEDL
HHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHEECCEEEEEEECCCCCCCCCCHHHH
EAVRAIIG
HHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA