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The map label for this gene is lolA [H]

Identifier: 218710025

GI number: 218710025

Start: 2193338

End: 2193937

Strand: Reverse

Name: lolA [H]

Synonym: VS_2045

Alternate gene names: 218710025

Gene position: 2193937-2193338 (Counterclockwise)

Preceding gene: 218710026

Following gene: 218710024

Centisome position: 66.5

GC content: 45.5

Gene sequence:

>600_bases
TTGATGAAAAAAGTATTCGCACTTTTATTTATGAGCTTCTCAGTATTTGCTTCTCCGAAAGAAGAGTTGAATAGCCGCTT
GTCGCTGAATGCAGGTTTTAGCGCTGACTTTAAACAAGTCGTCACCAGCCCTGATGGTGATGTTGTGATGGAAGGCGAGG
GTACGGTAGAGATTGCACGCCCTAGCTTGTTTCGTTGGGAAACGACTTTCCCTGATGAAAACCTATTGGTCTCTGATGGT
CAAAGCTTGTGGTACTACAGTCCGTTCATTGAACAAGTGAGCATTTACTGGCAAGAACAAGCCACATCGCAAACGCCATT
TGTATTGCTGACTCGTAACCAAGAAAGCGATTGGGACAACTACAACGTCGCGCAAACGGGTAACCAATTTACGCTAACGC
CAACGGCTGTGGACTCTAATCAGGGCGATTTCCAGATTAACATCACCAAGAAAGGCATTGTTCAGGGCTTTAATGTGATT
GAACAAGACGGCCAAAAAGGTGAGTTTACCTTTAACAATGTTGACTTAGGTAAACCTGCTGCTGACCGCTTTACTTTTGT
GGCGCCGGAAGGTGTCGAGGTCGACGACCAAAGAAACTGA

Upstream 100 bases:

>100_bases
CTTGGCGCCAGCGCCACCAAAAGATTAGTTCCAATAGGAACTCATAACTATTCAGTCGGTCAAAACCAAAACATGACCGA
CTTATGTTCTAACAGGATTA

Downstream 100 bases:

>100_bases
TCCAAACTGGCAGATCGTTTGGTAGTAAGTCGATAGGTATTGATGCCATCAACGAATCAAGAGATTGCAATTGAGTAATT
ACAGCTTAGATTTTGCGGGG

Product: outer-membrane lipoprotein carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MMKKVFALLFMSFSVFASPKEELNSRLSLNAGFSADFKQVVTSPDGDVVMEGEGTVEIARPSLFRWETTFPDENLLVSDG
QSLWYYSPFIEQVSIYWQEQATSQTPFVLLTRNQESDWDNYNVAQTGNQFTLTPTAVDSNQGDFQINITKKGIVQGFNVI
EQDGQKGEFTFNNVDLGKPAADRFTFVAPEGVEVDDQRN

Sequences:

>Translated_199_residues
MMKKVFALLFMSFSVFASPKEELNSRLSLNAGFSADFKQVVTSPDGDVVMEGEGTVEIARPSLFRWETTFPDENLLVSDG
QSLWYYSPFIEQVSIYWQEQATSQTPFVLLTRNQESDWDNYNVAQTGNQFTLTPTAVDSNQGDFQINITKKGIVQGFNVI
EQDGQKGEFTFNNVDLGKPAADRFTFVAPEGVEVDDQRN
>Mature_199_residues
MMKKVFALLFMSFSVFASPKEELNSRLSLNAGFSADFKQVVTSPDGDVVMEGEGTVEIARPSLFRWETTFPDENLLVSDG
QSLWYYSPFIEQVSIYWQEQATSQTPFVLLTRNQESDWDNYNVAQTGNQFTLTPTAVDSNQGDFQINITKKGIVQGFNVI
EQDGQKGEFTFNNVDLGKPAADRFTFVAPEGVEVDDQRN

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

Organism=Escherichia coli, GI145693108, Length=202, Percent_Identity=44.5544554455446, Blast_Score=182, Evalue=1e-47,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 22396; Mature: 22396

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKVFALLFMSFSVFASPKEELNSRLSLNAGFSADFKQVVTSPDGDVVMEGEGTVEIAR
CHHHHHHHHHHHHHHHCCCHHHHCCEEEECCCCCCCHHHHHCCCCCCEEECCCCEEEECC
PSLFRWETTFPDENLLVSDGQSLWYYSPFIEQVSIYWQEQATSQTPFVLLTRNQESDWDN
CCEEEEEECCCCCCEEEECCCEEEEECHHHHHHHEEEHHCCCCCCCEEEEECCCCCCCCC
YNVAQTGNQFTLTPTAVDSNQGDFQINITKKGIVQGFNVIEQDGQKGEFTFNNVDLGKPA
CEEEECCCEEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCC
ADRFTFVAPEGVEVDDQRN
CCCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MMKKVFALLFMSFSVFASPKEELNSRLSLNAGFSADFKQVVTSPDGDVVMEGEGTVEIAR
CHHHHHHHHHHHHHHHCCCHHHHCCEEEECCCCCCCHHHHHCCCCCCEEECCCCEEEECC
PSLFRWETTFPDENLLVSDGQSLWYYSPFIEQVSIYWQEQATSQTPFVLLTRNQESDWDN
CCEEEEEECCCCCCEEEECCCEEEEECHHHHHHHEEEHHCCCCCCCEEEEECCCCCCCCC
YNVAQTGNQFTLTPTAVDSNQGDFQINITKKGIVQGFNVIEQDGQKGEFTFNNVDLGKPA
CEEEECCCEEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCC
ADRFTFVAPEGVEVDDQRN
CCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA