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The map label for this gene is rarA [H]

Identifier: 218710024

GI number: 218710024

Start: 2191918

End: 2193273

Strand: Reverse

Name: rarA [H]

Synonym: VS_2044

Alternate gene names: 218710024

Gene position: 2193273-2191918 (Counterclockwise)

Preceding gene: 218710025

Following gene: 218710023

Centisome position: 66.48

GC content: 48.6

Gene sequence:

>1356_bases
TTGCAATTGAGTAATTACAGCTTAGATTTTGCGGGGGACGAAGATTTTCGTCCCCTTGCTGCTCGTATGAGACCTGAAAC
TGTTGAACAGTATATTGGTCAGCAGCATATATTAGGTCCAGGTAAACCCCTTCGCAGAGCGTTGGAGGCGGGCCATATCC
ACTCCATGATTTTATGGGGGCCTCCGGGCACCGGTAAAACCACGCTGGCAGAAGTGGCAGCTAATTACGCCAATGCAGAA
GTCGAGCGCGTGTCAGCAGTGACTTCGGGTGTAAAAGACATTCGTATCGCCATTGAAAAAGCGCGTGAGAACAAGCAAGC
AGGGCGTAGAACGATTCTATTTGTGGACGAAGTCCATCGCTTTAATAAAAGTCAGCAAGATGCGTTCTTACCTCATATCG
AAGATGGCACGGTTACGTTTATCGGCGCGACCACAGAAAACCCTTCTTTTGAGTTAAACAACGCTTTGTTATCACGTGCG
CGTGTCTACAAACTGACTTCGCTTAATACTGAGGATATCTCCCTCGTCATTCGCCAAGCCATTGAAGATAAACAGCGCGG
TCTGGGTGATGTAACGGCTGATTTTGCTGGTAACGTCTTAGATCGCCTCGCTGAACTGGTCAACGGTGACGCACGTATGT
CGCTCAACTATCTAGAGCTGCTGTATGACATGGCGGAAGACAACGACAAAGGCGAGAAAGCGATAACATTGCAGTTGTTA
GCTGAGGTGGCTGGTGAGAAGGTTGCTCGTTTCGATAACAAGGGTGATATTTGGTACGACCTAATCTCCGCCGTTCATAA
GTCGATTCGAGGCTCTAATCCCGATGCTGCGTTGTATTGGTCGGCGCGAATGATTGCAGCGGGCTGTGACCCTTTGTATA
TAGTAAGACGCTTGCTGGCGATTGCTTCTGAAGATATTGGTAATGCTGATCCAAGAGCAATGCAGGTCGCAATGTCGGCT
TGGGATTGCTTCACGCGTATTGGCCCAGCAGAAGGGGAGCGTGCGATTGCGCAGGCGGTTGTCTATCTAGCGTGTGCGCC
AAAGAGTAACGCTGTTTACACGGCTTGGAAGCAAGCCTTAACGGATGCTCACAACCTTCCTGAATATGAAGTCCCTCATC
ATTTACGTAATGCACCCACAACTTTGATGAAGGACATGGGCTACGGGCAAGAATACCGTTATGCTCATGATGAACCAGGT
GCCTACGCCGCTGGAGAAAATTATTTGCCGCCTGAAATGGGCGAAACACAATACTATTTCCCAACAAAACGAGGCTTAGA
GACCAAAATTGGCGAGAAGCTAGATTATCTGGCGGATTTGGACGCAAAAAGCCCACAAAAACGCTATGAAAAGTAG

Upstream 100 bases:

>100_bases
CCGGAAGGTGTCGAGGTCGACGACCAAAGAAACTGATCCAAACTGGCAGATCGTTTGGTAGTAAGTCGATAGGTATTGAT
GCCATCAACGAATCAAGAGA

Downstream 100 bases:

>100_bases
TCTTTTTTGGATATCGTTACCTAGTCATAAAAATTCAATTAAATCGTTACAAATTGGTCGAAATAGCACCAGTTTTAGGG
GTTTAGCAGTGATTCAGTAG

Product: recombination factor protein RarA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MQLSNYSLDFAGDEDFRPLAARMRPETVEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPPGTGKTTLAEVAANYANAE
VERVSAVTSGVKDIRIAIEKARENKQAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRA
RVYKLTSLNTEDISLVIRQAIEDKQRGLGDVTADFAGNVLDRLAELVNGDARMSLNYLELLYDMAEDNDKGEKAITLQLL
AEVAGEKVARFDNKGDIWYDLISAVHKSIRGSNPDAALYWSARMIAAGCDPLYIVRRLLAIASEDIGNADPRAMQVAMSA
WDCFTRIGPAEGERAIAQAVVYLACAPKSNAVYTAWKQALTDAHNLPEYEVPHHLRNAPTTLMKDMGYGQEYRYAHDEPG
AYAAGENYLPPEMGETQYYFPTKRGLETKIGEKLDYLADLDAKSPQKRYEK

Sequences:

>Translated_451_residues
MQLSNYSLDFAGDEDFRPLAARMRPETVEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPPGTGKTTLAEVAANYANAE
VERVSAVTSGVKDIRIAIEKARENKQAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRA
RVYKLTSLNTEDISLVIRQAIEDKQRGLGDVTADFAGNVLDRLAELVNGDARMSLNYLELLYDMAEDNDKGEKAITLQLL
AEVAGEKVARFDNKGDIWYDLISAVHKSIRGSNPDAALYWSARMIAAGCDPLYIVRRLLAIASEDIGNADPRAMQVAMSA
WDCFTRIGPAEGERAIAQAVVYLACAPKSNAVYTAWKQALTDAHNLPEYEVPHHLRNAPTTLMKDMGYGQEYRYAHDEPG
AYAAGENYLPPEMGETQYYFPTKRGLETKIGEKLDYLADLDAKSPQKRYEK
>Mature_451_residues
MQLSNYSLDFAGDEDFRPLAARMRPETVEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPPGTGKTTLAEVAANYANAE
VERVSAVTSGVKDIRIAIEKARENKQAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRA
RVYKLTSLNTEDISLVIRQAIEDKQRGLGDVTADFAGNVLDRLAELVNGDARMSLNYLELLYDMAEDNDKGEKAITLQLL
AEVAGEKVARFDNKGDIWYDLISAVHKSIRGSNPDAALYWSARMIAAGCDPLYIVRRLLAIASEDIGNADPRAMQVAMSA
WDCFTRIGPAEGERAIAQAVVYLACAPKSNAVYTAWKQALTDAHNLPEYEVPHHLRNAPTTLMKDMGYGQEYRYAHDEPG
AYAAGENYLPPEMGETQYYFPTKRGLETKIGEKLDYLADLDAKSPQKRYEK

Specific function: Unknown

COG id: COG2256

COG function: function code L; ATPase related to the helicase subunit of the Holliday junction resolvase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rarA family [H]

Homologues:

Organism=Homo sapiens, GI18426902, Length=440, Percent_Identity=42.7272727272727, Blast_Score=307, Evalue=1e-83,
Organism=Homo sapiens, GI18426904, Length=440, Percent_Identity=38.4090909090909, Blast_Score=248, Evalue=6e-66,
Organism=Escherichia coli, GI1787119, Length=447, Percent_Identity=73.8255033557047, Blast_Score=684, Evalue=0.0,
Organism=Escherichia coli, GI1786676, Length=291, Percent_Identity=25.4295532646048, Blast_Score=63, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324111, Length=456, Percent_Identity=37.719298245614, Blast_Score=300, Evalue=3e-82,
Organism=Saccharomyces cerevisiae, GI6324039, Length=236, Percent_Identity=26.271186440678, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR021886 [H]

Pfam domain/function: PF00004 AAA; PF12002 MgsA_C [H]

EC number: NA

Molecular weight: Translated: 50130; Mature: 50130

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSNYSLDFAGDEDFRPLAARMRPETVEQYIGQQHILGPGKPLRRALEAGHIHSMILWG
CCCCCCCEECCCCCCCHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEEEC
PPGTGKTTLAEVAANYANAEVERVSAVTSGVKDIRIAIEKARENKQAGRRTILFVDEVHR
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHH
FNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARVYKLTSLNTEDISLVIRQA
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IEDKQRGLGDVTADFAGNVLDRLAELVNGDARMSLNYLELLYDMAEDNDKGEKAITLQLL
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AEVAGEKVARFDNKGDIWYDLISAVHKSIRGSNPDAALYWSARMIAAGCDPLYIVRRLLA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHH
IASEDIGNADPRAMQVAMSAWDCFTRIGPAEGERAIAQAVVYLACAPKSNAVYTAWKQAL
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHH
TDAHNLPEYEVPHHLRNAPTTLMKDMGYGQEYRYAHDEPGAYAAGENYLPPEMGETQYYF
HHHHCCCCCCCCHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEC
PTKRGLETKIGEKLDYLADLDAKSPQKRYEK
CCCCCCHHHHHHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure
MQLSNYSLDFAGDEDFRPLAARMRPETVEQYIGQQHILGPGKPLRRALEAGHIHSMILWG
CCCCCCCEECCCCCCCHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEEEC
PPGTGKTTLAEVAANYANAEVERVSAVTSGVKDIRIAIEKARENKQAGRRTILFVDEVHR
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHH
FNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARVYKLTSLNTEDISLVIRQA
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IEDKQRGLGDVTADFAGNVLDRLAELVNGDARMSLNYLELLYDMAEDNDKGEKAITLQLL
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AEVAGEKVARFDNKGDIWYDLISAVHKSIRGSNPDAALYWSARMIAAGCDPLYIVRRLLA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHH
IASEDIGNADPRAMQVAMSAWDCFTRIGPAEGERAIAQAVVYLACAPKSNAVYTAWKQAL
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHH
TDAHNLPEYEVPHHLRNAPTTLMKDMGYGQEYRYAHDEPGAYAAGENYLPPEMGETQYYF
HHHHCCCCCCCCHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEC
PTKRGLETKIGEKLDYLADLDAKSPQKRYEK
CCCCCCHHHHHHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]