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The map label for this gene is torC [H]

Identifier: 218709985

GI number: 218709985

Start: 2152006

End: 2153187

Strand: Reverse

Name: torC [H]

Synonym: VS_2004

Alternate gene names: 218709985

Gene position: 2153187-2152006 (Counterclockwise)

Preceding gene: 218709986

Following gene: 218709984

Centisome position: 65.26

GC content: 43.91

Gene sequence:

>1182_bases
ATGAAATCATTTTTAGTTAAATTATGGCGCACAATGACTCGCCCTGCAGTACACATCAGTCTTGGTGTACTAACTATGGG
TGGCTTTATCGCCGGTGTTATTTTCTGGGGCGGTTTTAACACAGCTCTAGAGCACACAAATACAGAAGAGTTCTGTGTAA
GTTGTCACACCATGCGTGACAACGTGTACGTAGAACTACAAGAAACGGTTCACTGGAAAAACACTTCTGGTGTACGTGCT
ACTTGTCCTGACTGTCACGTTCCACATGAATGGACAGCAAAAATCGCTCGTAAGATGCAAGCATCTAAAGAAGTATTCGC
TCAAGTATTTGGTGACCTAGATACACCTGAGAAATTCGAAGCTCGTCGTATCGAACTGGCTAAACACGAATGGGATCGTT
TCTCTTCGAACAAATCTCTAGAGTGTAAAAACTGTCACAACTACGATTCAATGGACTTCGAGAACATGCGCCCAACAGCG
CGTATCCAGATGAAGAATGCAGCAGAACGTGATCAAAGCTGTGTTGACTGTCATAAAGGTATTGCTCACAACCTTCCAAT
GGATATGGCATCAGCAAGCGGTATTGTTGGCGAGCTAGAAAATGTAGCAAGCAGCACATCTTACGCAAATGGTTCTGACG
TGATCTCTATTCGTCACCTCCCAATGTACACGGATGAAACAGCAACAGTTGAAGCGGGTCTACTCAGCCCTGCAAGTAAA
GTAGCGGTTATCGACGAAAAAGGCGACATGATCAAGATTCAAATCGATGGTTGGCGTAAAGCGAAAGGCTTCGGACGTGT
AATCCAAGAAGACTTCGGTATGAACATCTCAACTGCAATCTTGACCAAAGAAGTATCTCAAAGTGACGTTATCACTGTTG
GTGAGAAGAAAGAAGATGAGCTTACTGGCCTTCCATGGGAAGAAGTTAACCTAGCACTTTGGATGAAGAAAGAGTCTATG
GTTGATAACTTCGATCCTATCTGGAACGCAGCGGGTCAAGCGTACCAATCTAACTGTTCAACGTGTCACTCACAGCCAGA
TGAAGCTCACTTCAGCGCTAACGGTTGGGTAGGCATGTTAGATGGTATGATTGCATTCGTTAACTTCGATACAGATACAG
AAGCACTTGTTCTTAAGTATCTACAGAAGCACTCATCAGATTTTTCTGAAGGCCATCACTAA

Upstream 100 bases:

>100_bases
CACTGCAAGTGTTTGTATTCGGACCTCCTGGTGCTCACGGCGGCATGTAATGCCCTCTAGTAACAACATTTTTTAAAATC
AATATTTAAGAGAGCTAAAC

Downstream 100 bases:

>100_bases
TAAGACGTCAATTGGAGTAACACAATGGCAATTACAAGAAGAAGTTTTCTGAAAGGTGTCGCTACTACAAGTGCGGCATC
GGTTATCGGTCCAAGCTTAT

Product: cytochrome c-type protein TorC

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKSFLVKLWRTMTRPAVHISLGVLTMGGFIAGVIFWGGFNTALEHTNTEEFCVSCHTMRDNVYVELQETVHWKNTSGVRA
TCPDCHVPHEWTAKIARKMQASKEVFAQVFGDLDTPEKFEARRIELAKHEWDRFSSNKSLECKNCHNYDSMDFENMRPTA
RIQMKNAAERDQSCVDCHKGIAHNLPMDMASASGIVGELENVASSTSYANGSDVISIRHLPMYTDETATVEAGLLSPASK
VAVIDEKGDMIKIQIDGWRKAKGFGRVIQEDFGMNISTAILTKEVSQSDVITVGEKKEDELTGLPWEEVNLALWMKKESM
VDNFDPIWNAAGQAYQSNCSTCHSQPDEAHFSANGWVGMLDGMIAFVNFDTDTEALVLKYLQKHSSDFSEGHH

Sequences:

>Translated_393_residues
MKSFLVKLWRTMTRPAVHISLGVLTMGGFIAGVIFWGGFNTALEHTNTEEFCVSCHTMRDNVYVELQETVHWKNTSGVRA
TCPDCHVPHEWTAKIARKMQASKEVFAQVFGDLDTPEKFEARRIELAKHEWDRFSSNKSLECKNCHNYDSMDFENMRPTA
RIQMKNAAERDQSCVDCHKGIAHNLPMDMASASGIVGELENVASSTSYANGSDVISIRHLPMYTDETATVEAGLLSPASK
VAVIDEKGDMIKIQIDGWRKAKGFGRVIQEDFGMNISTAILTKEVSQSDVITVGEKKEDELTGLPWEEVNLALWMKKESM
VDNFDPIWNAAGQAYQSNCSTCHSQPDEAHFSANGWVGMLDGMIAFVNFDTDTEALVLKYLQKHSSDFSEGHH
>Mature_393_residues
MKSFLVKLWRTMTRPAVHISLGVLTMGGFIAGVIFWGGFNTALEHTNTEEFCVSCHTMRDNVYVELQETVHWKNTSGVRA
TCPDCHVPHEWTAKIARKMQASKEVFAQVFGDLDTPEKFEARRIELAKHEWDRFSSNKSLECKNCHNYDSMDFENMRPTA
RIQMKNAAERDQSCVDCHKGIAHNLPMDMASASGIVGELENVASSTSYANGSDVISIRHLPMYTDETATVEAGLLSPASK
VAVIDEKGDMIKIQIDGWRKAKGFGRVIQEDFGMNISTAILTKEVSQSDVITVGEKKEDELTGLPWEEVNLALWMKKESM
VDNFDPIWNAAGQAYQSNCSTCHSQPDEAHFSANGWVGMLDGMIAFVNFDTDTEALVLKYLQKHSSDFSEGHH

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA. Acts by transferring electrons from the membranous menaquinones to TorA. This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal dom

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family [H]

Homologues:

Organism=Escherichia coli, GI1787230, Length=390, Percent_Identity=40.2564102564103, Blast_Score=301, Evalue=6e-83,
Organism=Escherichia coli, GI1788530, Length=182, Percent_Identity=53.2967032967033, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI1788181, Length=350, Percent_Identity=30, Blast_Score=171, Evalue=7e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126 [H]

Pfam domain/function: PF03264 Cytochrom_NNT [H]

EC number: NA

Molecular weight: Translated: 43986; Mature: 43986

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFLVKLWRTMTRPAVHISLGVLTMGGFIAGVIFWGGFNTALEHTNTEEFCVSCHTMRD
CHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHEEECC
NVYVELQETVHWKNTSGVRATCPDCHVPHEWTAKIARKMQASKEVFAQVFGDLDTPEKFE
CEEEEEEHHEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ARRIELAKHEWDRFSSNKSLECKNCHNYDSMDFENMRPTARIQMKNAAERDQSCVDCHKG
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHH
IAHNLPMDMASASGIVGELENVASSTSYANGSDVISIRHLPMYTDETATVEAGLLSPASK
HHHCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEECCCCCCCCC
VAVIDEKGDMIKIQIDGWRKAKGFGRVIQEDFGMNISTAILTKEVSQSDVITVGEKKEDE
EEEEECCCCEEEEEECCCHHCHHHHHHHHHHHCCCEEHHHHHHHCCCCCEEEECCCCCCC
LTGLPWEEVNLALWMKKESMVDNFDPIWNAAGQAYQSNCSTCHSQPDEAHFSANGWVGML
CCCCCHHHCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHH
DGMIAFVNFDTDTEALVLKYLQKHSSDFSEGHH
CCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKSFLVKLWRTMTRPAVHISLGVLTMGGFIAGVIFWGGFNTALEHTNTEEFCVSCHTMRD
CHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHEEECC
NVYVELQETVHWKNTSGVRATCPDCHVPHEWTAKIARKMQASKEVFAQVFGDLDTPEKFE
CEEEEEEHHEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ARRIELAKHEWDRFSSNKSLECKNCHNYDSMDFENMRPTARIQMKNAAERDQSCVDCHKG
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHH
IAHNLPMDMASASGIVGELENVASSTSYANGSDVISIRHLPMYTDETATVEAGLLSPASK
HHHCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEECCCCCCCCC
VAVIDEKGDMIKIQIDGWRKAKGFGRVIQEDFGMNISTAILTKEVSQSDVITVGEKKEDE
EEEEECCCCEEEEEECCCHHCHHHHHHHHHHHCCCEEHHHHHHHCCCCCEEEECCCCCCC
LTGLPWEEVNLALWMKKESMVDNFDPIWNAAGQAYQSNCSTCHSQPDEAHFSANGWVGML
CCCCCHHHCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCHHHH
DGMIAFVNFDTDTEALVLKYLQKHSSDFSEGHH
CCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]