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The map label for this gene is torA [H]

Identifier: 218709984

GI number: 218709984

Start: 2149519

End: 2151981

Strand: Reverse

Name: torA [H]

Synonym: VS_2003

Alternate gene names: 218709984

Gene position: 2151981-2149519 (Counterclockwise)

Preceding gene: 218709985

Following gene: 218709982

Centisome position: 65.23

GC content: 47.02

Gene sequence:

>2463_bases
ATGGCAATTACAAGAAGAAGTTTTCTGAAAGGTGTCGCTACTACAAGTGCGGCATCGGTTATCGGTCCAAGCTTATTGGC
GTCGGCATCAGCGTCTGCAGCAGAAACAGACGGCGCGTGGAAAGTCTCTGGTTCTCACTGGGGTGCATTCCGAGCTCGCG
TTTATGCGGGTAAAGTACAAGAGATTAAACCTCTAGAAATCGATCAACACCCAACTGAGATGTTGAAAGGTATTAAAGGT
ATTATCTACAGCCCATCACGTGTGCGTTACCCAATGGTTCGCCTAGATTGGTTGAAGAAGCATAAATACAGCGCAGACAC
GCGTGGTAACAACCGTTTTATTCGTGTGACTTGGGATGAGGCACTAGACCTTGTTTACCGCGAACTAGAGCGCGTGCAGA
AAGATTACGGTCCATGGGCGCTTCACACAGGTCAAACTGGTTGGAGACAAACGGGTCAGTTCCACAGCTGTACTAACCAT
ATGCAACGTGCAATGGCACTTCACGGTTACTCTGTGAAGAAAATCGGTGACTACTCAACAGGTGCTGGTCAAACGATCAT
GCCTTACGTGCTAGGTTCTACTGAAGTTTACGCACAAGGTACATCTTGGGAACTTATCCTAGAAAACAGTGACAACATTG
TTCTTTGGGGTAACGATCCAGTTAAAAACCTGCAAGTAGGTTGGACATGTGAGACTCACGAGTCATTCGCATACTTAGAA
CAGCTGAAAGAAAAAGTTGCTAAGAAAGAGATCAACGTTGTTTCTGTTGACCCTGTTAAAAACAAAACAGGCCGTTACCT
AGAAAACGAGCAAATGTACATCAACCCACAAACTGATGTGGCGTTCATGCTTGGTGTTGCTCACGTTCTTTACAACGAAG
ATCTATACGACAAGAAGTTCATCGAAACTTACTGTCTAGGTTTTGAAGATTTTATCAAGTACGTTCAAGGTGAAACGAAA
GATAAAGTTGAGAAGACACCTGAGTGGGCTTCGGCTATCTGTGGTGCAAGCGCGGACTCTATCCGTGAATTCGCTAAGAT
GCTGGTTAACGGTCGTACGCAGATTCTTGTCGGTTGGAGTATCCAACGTCAACAACACGGTGAGCAGCCTTACTGGATGT
GTGCCGTTATCGCAGCAATGGTTGGCCAAATCGGTTTACCTGGCGGTGGTATCTCTTACGGTCACCATTACTCTGGTATC
GGTGTTTCTTCAACTGGCTTCGCTGCTCCGGGTTCATTCCCGTTGAACATCGACCAAGGTCAATCGCCTAAGCACACTAA
CACTGATTACAACGGTTACAGCCGTGTAATCCCTGTTGCTCGTTGGGTAGATAGTTTGCTAGAGCCAGGTAAGAAGATCA
AAGCGAACGGTTCAACGGTAACACTACCTGATATCAAGATGATGGTATTCAGTGGTAATAACCCGTGGCACCACCACCAA
GATCGCAACAAGATGCGTAAAGCATTCAAGAGCCTACAAACTGTAGTGGCTGTTGATTTCGCTTGGACTGCAACTTGTCG
TCACTCTGATATCGTGCTTCCTGCATGTACTCAGTGGGAACGTAACGATATTGATGGTTACGGCGCGTACTCTGGTCGTG
GTTTGATCGCGATGCACAAACTAGTCGATCCTCTGTTCCAGTCTAAAACTGACTTCGAGATTATGTCTAGCCTAACTAAG
CGTTGGGGTCGTTACGACGATTATACGCGTGGTATGGACGAAATGCAGTGGGTTAAATCTCTGTATGACGAATGTCGTGC
ATCAAACGAAGGCAGCTTCGAAATGCCTGAGTTTGCTGAGTTCTGGGAGAAAGGTTTCCTAGACTTCGGTAAAGGTAAGC
CATGGACTCGTCACGCTTCATTCCGTGAAGATCCAGAGATCAACGCACTAGGTACGCCTTCTGGTTTCATCGAAATCACA
AGCCGTACTGTTGGCAACATGGGTTACGAGCACTGTCAAGAACACCCAATGTGGTTTGAGAAATCTGAACGTTCACACGG
TGGTCCAGGCTCTGACAAACATCCGTACTGGCTACAATCTTGTCACCCAGACAAGCGTCTTCACTCTCAGATGTGTGAAT
CTGAAGAGTGGCGTGCGACTTACGCGGTACAAGGCCGTGAGCCAATCTACATCAACCCAATCGATGCTAAGAAGAAAGGC
ATCAAAGATGGCGACGTAGTACGTGTGTTCAATGACCGTGGTCAACTACTAGCAGGTGCTGTTCTAATGGATAGCTACGC
ACCTGGTGTTGTTCGTATCGAAGAAGGCGCTTGGTACGGCCCGATCAACGAGAAAGTGGGGGCGCTAGATACATACGGCG
ATCCAAACACACTAACTCAAGACATCGGTACGTCTGAACTTGCTCAAGCAACGTCAGCAAACACATGTTTGGTTAACTTC
GAGAAGTTCCAAGGCAAACTGCCTCCAGTAACTTCATTCGGTGGTCCAATCGAAGTTTCTTAA

Upstream 100 bases:

>100_bases
CGATACAGATACAGAAGCACTTGTTCTTAAGTATCTACAGAAGCACTCATCAGATTTTTCTGAAGGCCATCACTAATAAG
ACGTCAATTGGAGTAACACA

Downstream 100 bases:

>100_bases
GTCTTGTACTTAAGAACCAAGATTAAAGCTTGAATTAAAGCCCCTGTAAGCACTCTTACAGGGGCTTTTTGTTTTTCTAA
CCTGTGTGTGGGATTTGTAA

Product: putative trimethylamine-N-oxide reductase

Products: NA

Alternate protein names: TMAO reductase; Trimethylamine oxidase [H]

Number of amino acids: Translated: 820; Mature: 819

Protein sequence:

>820_residues
MAITRRSFLKGVATTSAASVIGPSLLASASASAAETDGAWKVSGSHWGAFRARVYAGKVQEIKPLEIDQHPTEMLKGIKG
IIYSPSRVRYPMVRLDWLKKHKYSADTRGNNRFIRVTWDEALDLVYRELERVQKDYGPWALHTGQTGWRQTGQFHSCTNH
MQRAMALHGYSVKKIGDYSTGAGQTIMPYVLGSTEVYAQGTSWELILENSDNIVLWGNDPVKNLQVGWTCETHESFAYLE
QLKEKVAKKEINVVSVDPVKNKTGRYLENEQMYINPQTDVAFMLGVAHVLYNEDLYDKKFIETYCLGFEDFIKYVQGETK
DKVEKTPEWASAICGASADSIREFAKMLVNGRTQILVGWSIQRQQHGEQPYWMCAVIAAMVGQIGLPGGGISYGHHYSGI
GVSSTGFAAPGSFPLNIDQGQSPKHTNTDYNGYSRVIPVARWVDSLLEPGKKIKANGSTVTLPDIKMMVFSGNNPWHHHQ
DRNKMRKAFKSLQTVVAVDFAWTATCRHSDIVLPACTQWERNDIDGYGAYSGRGLIAMHKLVDPLFQSKTDFEIMSSLTK
RWGRYDDYTRGMDEMQWVKSLYDECRASNEGSFEMPEFAEFWEKGFLDFGKGKPWTRHASFREDPEINALGTPSGFIEIT
SRTVGNMGYEHCQEHPMWFEKSERSHGGPGSDKHPYWLQSCHPDKRLHSQMCESEEWRATYAVQGREPIYINPIDAKKKG
IKDGDVVRVFNDRGQLLAGAVLMDSYAPGVVRIEEGAWYGPINEKVGALDTYGDPNTLTQDIGTSELAQATSANTCLVNF
EKFQGKLPPVTSFGGPIEVS

Sequences:

>Translated_820_residues
MAITRRSFLKGVATTSAASVIGPSLLASASASAAETDGAWKVSGSHWGAFRARVYAGKVQEIKPLEIDQHPTEMLKGIKG
IIYSPSRVRYPMVRLDWLKKHKYSADTRGNNRFIRVTWDEALDLVYRELERVQKDYGPWALHTGQTGWRQTGQFHSCTNH
MQRAMALHGYSVKKIGDYSTGAGQTIMPYVLGSTEVYAQGTSWELILENSDNIVLWGNDPVKNLQVGWTCETHESFAYLE
QLKEKVAKKEINVVSVDPVKNKTGRYLENEQMYINPQTDVAFMLGVAHVLYNEDLYDKKFIETYCLGFEDFIKYVQGETK
DKVEKTPEWASAICGASADSIREFAKMLVNGRTQILVGWSIQRQQHGEQPYWMCAVIAAMVGQIGLPGGGISYGHHYSGI
GVSSTGFAAPGSFPLNIDQGQSPKHTNTDYNGYSRVIPVARWVDSLLEPGKKIKANGSTVTLPDIKMMVFSGNNPWHHHQ
DRNKMRKAFKSLQTVVAVDFAWTATCRHSDIVLPACTQWERNDIDGYGAYSGRGLIAMHKLVDPLFQSKTDFEIMSSLTK
RWGRYDDYTRGMDEMQWVKSLYDECRASNEGSFEMPEFAEFWEKGFLDFGKGKPWTRHASFREDPEINALGTPSGFIEIT
SRTVGNMGYEHCQEHPMWFEKSERSHGGPGSDKHPYWLQSCHPDKRLHSQMCESEEWRATYAVQGREPIYINPIDAKKKG
IKDGDVVRVFNDRGQLLAGAVLMDSYAPGVVRIEEGAWYGPINEKVGALDTYGDPNTLTQDIGTSELAQATSANTCLVNF
EKFQGKLPPVTSFGGPIEVS
>Mature_819_residues
AITRRSFLKGVATTSAASVIGPSLLASASASAAETDGAWKVSGSHWGAFRARVYAGKVQEIKPLEIDQHPTEMLKGIKGI
IYSPSRVRYPMVRLDWLKKHKYSADTRGNNRFIRVTWDEALDLVYRELERVQKDYGPWALHTGQTGWRQTGQFHSCTNHM
QRAMALHGYSVKKIGDYSTGAGQTIMPYVLGSTEVYAQGTSWELILENSDNIVLWGNDPVKNLQVGWTCETHESFAYLEQ
LKEKVAKKEINVVSVDPVKNKTGRYLENEQMYINPQTDVAFMLGVAHVLYNEDLYDKKFIETYCLGFEDFIKYVQGETKD
KVEKTPEWASAICGASADSIREFAKMLVNGRTQILVGWSIQRQQHGEQPYWMCAVIAAMVGQIGLPGGGISYGHHYSGIG
VSSTGFAAPGSFPLNIDQGQSPKHTNTDYNGYSRVIPVARWVDSLLEPGKKIKANGSTVTLPDIKMMVFSGNNPWHHHQD
RNKMRKAFKSLQTVVAVDFAWTATCRHSDIVLPACTQWERNDIDGYGAYSGRGLIAMHKLVDPLFQSKTDFEIMSSLTKR
WGRYDDYTRGMDEMQWVKSLYDECRASNEGSFEMPEFAEFWEKGFLDFGKGKPWTRHASFREDPEINALGTPSGFIEITS
RTVGNMGYEHCQEHPMWFEKSERSHGGPGSDKHPYWLQSCHPDKRLHSQMCESEEWRATYAVQGREPIYINPIDAKKKGI
KDGDVVRVFNDRGQLLAGAVLMDSYAPGVVRIEEGAWYGPINEKVGALDTYGDPNTLTQDIGTSELAQATSANTCLVNFE
KFQGKLPPVTSFGGPIEVS

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787231, Length=835, Percent_Identity=51.497005988024, Blast_Score=860, Evalue=0.0,
Organism=Escherichia coli, GI87081994, Length=825, Percent_Identity=37.8181818181818, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI145693196, Length=786, Percent_Identity=37.4045801526718, Blast_Score=543, Evalue=1e-155,
Organism=Escherichia coli, GI87081797, Length=863, Percent_Identity=29.5480880648899, Blast_Score=294, Evalue=2e-80,
Organism=Escherichia coli, GI1787870, Length=864, Percent_Identity=28.9351851851852, Blast_Score=267, Evalue=2e-72,
Organism=Escherichia coli, GI171474008, Length=865, Percent_Identity=27.2832369942196, Blast_Score=250, Evalue=3e-67,
Organism=Escherichia coli, GI3868721, Length=698, Percent_Identity=24.2120343839542, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR011887 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 91986; Mature: 91855

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITRRSFLKGVATTSAASVIGPSLLASASASAAETDGAWKVSGSHWGAFRARVYAGKVQ
CCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCEEECCCCCCHHHEEEEECCCC
EIKPLEIDQHPTEMLKGIKGIIYSPSRVRYPMVRLDWLKKHKYSADTRGNNRFIRVTWDE
CCCCCCCCCCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHH
ALDLVYRELERVQKDYGPWALHTGQTGWRQTGQFHSCTNHMQRAMALHGYSVKKIGDYST
HHHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
GAGQTIMPYVLGSTEVYAQGTSWELILENSDNIVLWGNDPVKNLQVGWTCETHESFAYLE
CCCCEEEHEEECCCEEEECCCCEEEEEECCCCEEEECCCCCCCEEEEEEECCHHHHHHHH
QLKEKVAKKEINVVSVDPVKNKTGRYLENEQMYINPQTDVAFMLGVAHVLYNEDLYDKKF
HHHHHHHHHHCCEEEECCCCCCCCCEECCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHH
IETYCLGFEDFIKYVQGETKDKVEKTPEWASAICGASADSIREFAKMLVNGRTQILVGWS
HHHHHCCHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEE
IQRQQHGEQPYWMCAVIAAMVGQIGLPGGGISYGHHYSGIGVSSTGFAAPGSFPLNIDQG
EHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCC
QSPKHTNTDYNGYSRVIPVARWVDSLLEPGKKIKANGSTVTLPDIKMMVFSGNNPWHHHQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCEEECCCEEEEEEECCCCCCCCH
DRNKMRKAFKSLQTVVAVDFAWTATCRHSDIVLPACTQWERNDIDGYGAYSGRGLIAMHK
HHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHH
LVDPLFQSKTDFEIMSSLTKRWGRYDDYTRGMDEMQWVKSLYDECRASNEGSFEMPEFAE
HHHHHHCCCCCHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
FWEKGFLDFGKGKPWTRHASFREDPEINALGTPSGFIEITSRTVGNMGYEHCQEHPMWFE
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHCCCHHHHHHCCCCCC
KSERSHGGPGSDKHPYWLQSCHPDKRLHSQMCESEEWRATYAVQGREPIYINPIDAKKKG
CCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCHHHCC
IKDGDVVRVFNDRGQLLAGAVLMDSYAPGVVRIEEGAWYGPINEKVGALDTYGDPNTLTQ
CCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCHHHH
DIGTSELAQATSANTCLVNFEKFQGKLPPVTSFGGPIEVS
HCCHHHHHHHCCCCEEEEEEHHHCCCCCCCCCCCCCEECC
>Mature Secondary Structure 
AITRRSFLKGVATTSAASVIGPSLLASASASAAETDGAWKVSGSHWGAFRARVYAGKVQ
CCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCEEECCCCCCHHHEEEEECCCC
EIKPLEIDQHPTEMLKGIKGIIYSPSRVRYPMVRLDWLKKHKYSADTRGNNRFIRVTWDE
CCCCCCCCCCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEHHH
ALDLVYRELERVQKDYGPWALHTGQTGWRQTGQFHSCTNHMQRAMALHGYSVKKIGDYST
HHHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
GAGQTIMPYVLGSTEVYAQGTSWELILENSDNIVLWGNDPVKNLQVGWTCETHESFAYLE
CCCCEEEHEEECCCEEEECCCCEEEEEECCCCEEEECCCCCCCEEEEEEECCHHHHHHHH
QLKEKVAKKEINVVSVDPVKNKTGRYLENEQMYINPQTDVAFMLGVAHVLYNEDLYDKKF
HHHHHHHHHHCCEEEECCCCCCCCCEECCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHH
IETYCLGFEDFIKYVQGETKDKVEKTPEWASAICGASADSIREFAKMLVNGRTQILVGWS
HHHHHCCHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEE
IQRQQHGEQPYWMCAVIAAMVGQIGLPGGGISYGHHYSGIGVSSTGFAAPGSFPLNIDQG
EHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCC
QSPKHTNTDYNGYSRVIPVARWVDSLLEPGKKIKANGSTVTLPDIKMMVFSGNNPWHHHQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCEEECCCEEEEEEECCCCCCCCH
DRNKMRKAFKSLQTVVAVDFAWTATCRHSDIVLPACTQWERNDIDGYGAYSGRGLIAMHK
HHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHH
LVDPLFQSKTDFEIMSSLTKRWGRYDDYTRGMDEMQWVKSLYDECRASNEGSFEMPEFAE
HHHHHHCCCCCHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
FWEKGFLDFGKGKPWTRHASFREDPEINALGTPSGFIEITSRTVGNMGYEHCQEHPMWFE
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHCCCHHHHHHCCCCCC
KSERSHGGPGSDKHPYWLQSCHPDKRLHSQMCESEEWRATYAVQGREPIYINPIDAKKKG
CCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCHHHCC
IKDGDVVRVFNDRGQLLAGAVLMDSYAPGVVRIEEGAWYGPINEKVGALDTYGDPNTLTQ
CCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCHHHH
DIGTSELAQATSANTCLVNFEKFQGKLPPVTSFGGPIEVS
HCCHHHHHHHCCCCEEEEEEHHHCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]