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The map label for this gene is ubiG

Identifier: 218709924

GI number: 218709924

Start: 2081761

End: 2082474

Strand: Direct

Name: ubiG

Synonym: VS_1937

Alternate gene names: 218709924

Gene position: 2081761-2082474 (Clockwise)

Preceding gene: 218709921

Following gene: 218709926

Centisome position: 63.1

GC content: 46.78

Gene sequence:

>714_bases
ATGACTAAATCACAAAACGTAGACCCAGCAGAAATCAAAAAATTCGAAGACATGGCGTCGCGCTGGTGGGATCTAGAAGG
CGAGTTTAAGCCACTACATCAAATCAACCCACTGCGCCTAAATTACGTTCTAGAGAAAACCGAAGGCCTATTTGGCAAGA
AAGTTCTCGATGTTGGCTGCGGTGGCGGTATTTTGGCTGAGAGCATGGCCGTTGAAGGTGCGGTAGTTACGGGCCTAGAC
ATGGGTAAAGAGCCGCTAGAAGTAGCGCGCCTTCACGCATTGGAAACTGGCACCAAGCTGGATTACATTCAGAGCACTAT
CGAAGACCACGCAGAACAGAACCCACAGGCTTACGATGTGGTAACGTGCATGGAAATGCTTGAGCATGTTCCTGACCCAC
AATCCGTTATCACGGCATGTTCAAAGTTAGTGAAACCGGGCGGCCATGTCTTCTTCTCTACGTTAAATCGCAACTTCAAA
TCTTACTTGTTTGCGATTGTTGGAGCAGAAAAGCTCTTGAAGATAGTTCCAGAAGGTACTCACGACCACGAAAAGTTCAT
TCGCCCAGCTGAACTTATCAAGATGATAGACAACACTCCGCTGCAAGAATTGGGGATTACAGGACTGCACTACAACCCGT
TAACGGACACTTATCGTTTGGGCACAAATGTAGATGTTAACTACATAGTCCACACGCAAAATCTCACCCAATAA

Upstream 100 bases:

>100_bases
AATAAACTAGCAAAATTGTAGATCTTCTGGTCAGCAGGAAAAGGCAAGTTATAATGCCTGCAATTTCATGGATGCATTAT
TTAACTTGGAAATGCCGATT

Downstream 100 bases:

>100_bases
CTATTAATATCCCCAGCTTAAAATCTTTTAGAAAAAGACGATTGAAAAGAGTTGTAATTAACATAACTTTACGACTTTTT
TCAGTCTAAATTTCGTGCGC

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTKSQNVDPAEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLEKTEGLFGKKVLDVGCGGGILAESMAVEGAVVTGLD
MGKEPLEVARLHALETGTKLDYIQSTIEDHAEQNPQAYDVVTCMEMLEHVPDPQSVITACSKLVKPGGHVFFSTLNRNFK
SYLFAIVGAEKLLKIVPEGTHDHEKFIRPAELIKMIDNTPLQELGITGLHYNPLTDTYRLGTNVDVNYIVHTQNLTQ

Sequences:

>Translated_237_residues
MTKSQNVDPAEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLEKTEGLFGKKVLDVGCGGGILAESMAVEGAVVTGLD
MGKEPLEVARLHALETGTKLDYIQSTIEDHAEQNPQAYDVVTCMEMLEHVPDPQSVITACSKLVKPGGHVFFSTLNRNFK
SYLFAIVGAEKLLKIVPEGTHDHEKFIRPAELIKMIDNTPLQELGITGLHYNPLTDTYRLGTNVDVNYIVHTQNLTQ
>Mature_236_residues
TKSQNVDPAEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLEKTEGLFGKKVLDVGCGGGILAESMAVEGAVVTGLDM
GKEPLEVARLHALETGTKLDYIQSTIEDHAEQNPQAYDVVTCMEMLEHVPDPQSVITACSKLVKPGGHVFFSTLNRNFKS
YLFAIVGAEKLLKIVPEGTHDHEKFIRPAELIKMIDNTPLQELGITGLHYNPLTDTYRLGTNVDVNYIVHTQNLTQ

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=243, Percent_Identity=34.156378600823, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI1788564, Length=231, Percent_Identity=70.995670995671, Blast_Score=357, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI115533050, Length=234, Percent_Identity=33.7606837606838, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324476, Length=285, Percent_Identity=30.8771929824561, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI281365311, Length=236, Percent_Identity=32.6271186440678, Blast_Score=151, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24585589, Length=225, Percent_Identity=32.4444444444444, Blast_Score=140, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_VIBSL (B7VGS0)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002417545.1
- ProteinModelPortal:   B7VGS0
- GeneID:   7161499
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_1937
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- ProtClustDB:   PRK05134
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 26476; Mature: 26344

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSQNVDPAEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLEKTEGLFGKKVLDVGC
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCC
GGGILAESMAVEGAVVTGLDMGKEPLEVARLHALETGTKLDYIQSTIEDHAEQNPQAYDV
CCHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
VTCMEMLEHVPDPQSVITACSKLVKPGGHVFFSTLNRNFKSYLFAIVGAEKLLKIVPEGT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HDHEKFIRPAELIKMIDNTPLQELGITGLHYNPLTDTYRLGTNVDVNYIVHTQNLTQ
CCHHHHCCHHHHHHHHCCCCHHHHCCCCCCCCCCCCCEECCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
TKSQNVDPAEIKKFEDMASRWWDLEGEFKPLHQINPLRLNYVLEKTEGLFGKKVLDVGC
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCC
GGGILAESMAVEGAVVTGLDMGKEPLEVARLHALETGTKLDYIQSTIEDHAEQNPQAYDV
CCHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
VTCMEMLEHVPDPQSVITACSKLVKPGGHVFFSTLNRNFKSYLFAIVGAEKLLKIVPEGT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HDHEKFIRPAELIKMIDNTPLQELGITGLHYNPLTDTYRLGTNVDVNYIVHTQNLTQ
CCHHHHCCHHHHHHHHCCCCHHHHCCCCCCCCCCCCCEECCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA