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The map label for this gene is sdaC [H]

Identifier: 218709791

GI number: 218709791

Start: 1931997

End: 1933250

Strand: Direct

Name: sdaC [H]

Synonym: VS_1803

Alternate gene names: 218709791

Gene position: 1931997-1933250 (Clockwise)

Preceding gene: 218709790

Following gene: 218709792

Centisome position: 58.56

GC content: 43.06

Gene sequence:

>1254_bases
ATGAACACAACAACTTCTTCGGCAAATGCCGTTACAGATACAAGCAAGTTTAACTATAAAGATTTTACCTGGTGTCTATC
ACTATTCGGTACAGCAGTTGGCGCTGGTGTACTATTCCTTCCAATCAAAGCTGGTGCGGGTGGTTTTTGGCCACTAGTTA
TCCTAGCTTTAATCGCGGCACCAATGACTTGGTTCGCACACAAATCTCTAGCTCGTTTCGTACTGTCTTCTAAGAACCCT
GAAGCAGATATTACAGACACAGTTGAAGAACACTTCGGTAAGACTGGCGCGAACCTTATTACTTTCGCTTACTTTTTCGC
TATCTACCCAATCGTTCTTATCTACGGTGTTGGTATTACAAACACAGTTGACTCTTTCCTAGTAAACCAAATGGGCATGG
AATCTATTCCTCGTCCTCTTCTTTCTGGTGCACTTATCCTTGCTATGACAGCAGGTGTTGTATTCGGTAAAGAGCTGATG
CTTAAAGCAACTTCAGCAATGGTTTACCCACTAGTATTCATCCTACTAGCATTGTCTTTCTACCTAGTTCCTGATTGGAA
CACTTCAATGATGGAAACAAGCCCAGAATGGTCAGCAATGCCTTCTATTATCTGGCTTGCGATTCCAATCATCGTGTTCT
CTTTCAACCACAGCCCAATCATTTCACAGTTCTCTAAAGAGCAACGTCGTGTATACGGTGAAGACGCGGTTAAGAAAACT
GACGCGATCACTGGTGGCGCAGCAATGATGCTGATGGGTTTTGTAATGTTCTTCGTTTTCTCTGTAGTACTTTCTCTATC
TCCAGAGCAACTAGCAACAGCGCAATCTCAAAACATCTCTGTACTTTCTTACCTAGCTAACGTTCACGAGTCTCCACTTA
TCTCTTACATGGGTCCTCTAGTAGCGTTCGCAGCGATTACTTCAAGCTACTTCGGTCACTTCCTAGGTGCTCACGAAGGT
CTTGTTGGTCTAATTAAGTCTCGCTCTGGTTCTTCAGTAAGTACTATCGAAAAAGCTTCTCTAGCGTTCATCGTTGTTAC
AACTTGGATTGTTGCGGTAGTTAACCCAAGCATCCTAGGTATGATTGAAACAATGGGTGCTCCAATGATTGCAGCTATCC
TGTTCCTAATGCCTGTATTCGCAATGAACAAAGTACCAGCTATGGCTAAGTACAAAACTTCAGCACCTGTGCAAATCTTT
ACAGCTTTATGTGGTCTAGCGGCTATTAGTTCTGTAATCTACGGCGCTCTTTAA

Upstream 100 bases:

>100_bases
CGCCGTTTCATTACATGATTTAGATCTATTTTTTGTAGAAGAAAATTCTGCAGAATTAGCCCCGACTTATTTCCTGTTCC
CAAAAAATGAGTAATTTAAC

Downstream 100 bases:

>100_bases
TCTCAAGCCCTTTTTATAAGATGACATTCATCTTATATGGCGAGGTTAGACAAAAAATATAATGATAATAAATGAGCCTC
CCTACTCCCCTTGGGAGGCT

Product: serine transporter

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MNTTTSSANAVTDTSKFNYKDFTWCLSLFGTAVGAGVLFLPIKAGAGGFWPLVILALIAAPMTWFAHKSLARFVLSSKNP
EADITDTVEEHFGKTGANLITFAYFFAIYPIVLIYGVGITNTVDSFLVNQMGMESIPRPLLSGALILAMTAGVVFGKELM
LKATSAMVYPLVFILLALSFYLVPDWNTSMMETSPEWSAMPSIIWLAIPIIVFSFNHSPIISQFSKEQRRVYGEDAVKKT
DAITGGAAMMLMGFVMFFVFSVVLSLSPEQLATAQSQNISVLSYLANVHESPLISYMGPLVAFAAITSSYFGHFLGAHEG
LVGLIKSRSGSSVSTIEKASLAFIVVTTWIVAVVNPSILGMIETMGAPMIAAILFLMPVFAMNKVPAMAKYKTSAPVQIF
TALCGLAAISSVIYGAL

Sequences:

>Translated_417_residues
MNTTTSSANAVTDTSKFNYKDFTWCLSLFGTAVGAGVLFLPIKAGAGGFWPLVILALIAAPMTWFAHKSLARFVLSSKNP
EADITDTVEEHFGKTGANLITFAYFFAIYPIVLIYGVGITNTVDSFLVNQMGMESIPRPLLSGALILAMTAGVVFGKELM
LKATSAMVYPLVFILLALSFYLVPDWNTSMMETSPEWSAMPSIIWLAIPIIVFSFNHSPIISQFSKEQRRVYGEDAVKKT
DAITGGAAMMLMGFVMFFVFSVVLSLSPEQLATAQSQNISVLSYLANVHESPLISYMGPLVAFAAITSSYFGHFLGAHEG
LVGLIKSRSGSSVSTIEKASLAFIVVTTWIVAVVNPSILGMIETMGAPMIAAILFLMPVFAMNKVPAMAKYKTSAPVQIF
TALCGLAAISSVIYGAL
>Mature_417_residues
MNTTTSSANAVTDTSKFNYKDFTWCLSLFGTAVGAGVLFLPIKAGAGGFWPLVILALIAAPMTWFAHKSLARFVLSSKNP
EADITDTVEEHFGKTGANLITFAYFFAIYPIVLIYGVGITNTVDSFLVNQMGMESIPRPLLSGALILAMTAGVVFGKELM
LKATSAMVYPLVFILLALSFYLVPDWNTSMMETSPEWSAMPSIIWLAIPIIVFSFNHSPIISQFSKEQRRVYGEDAVKKT
DAITGGAAMMLMGFVMFFVFSVVLSLSPEQLATAQSQNISVLSYLANVHESPLISYMGPLVAFAAITSSYFGHFLGAHEG
LVGLIKSRSGSSVSTIEKASLAFIVVTTWIVAVVNPSILGMIETMGAPMIAAILFLMPVFAMNKVPAMAKYKTSAPVQIF
TALCGLAAISSVIYGAL

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=426, Percent_Identity=51.6431924882629, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI1789504, Length=442, Percent_Identity=41.4027149321267, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI1789211, Length=399, Percent_Identity=35.0877192982456, Blast_Score=238, Evalue=8e-64,
Organism=Escherichia coli, GI1789961, Length=391, Percent_Identity=27.3657289002558, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI145693183, Length=394, Percent_Identity=22.5888324873096, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 44804; Mature: 44804

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTTSSANAVTDTSKFNYKDFTWCLSLFGTAVGAGVLFLPIKAGAGGFWPLVILALIAA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHH
PMTWFAHKSLARFVLSSKNPEADITDTVEEHFGKTGANLITFAYFFAIYPIVLIYGVGIT
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
NTVDSFLVNQMGMESIPRPLLSGALILAMTAGVVFGKELMLKATSAMVYPLVFILLALSF
HHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLVPDWNTSMMETSPEWSAMPSIIWLAIPIIVFSFNHSPIISQFSKEQRRVYGEDAVKKT
HCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
DAITGGAAMMLMGFVMFFVFSVVLSLSPEQLATAQSQNISVLSYLANVHESPLISYMGPL
HCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHH
VAFAAITSSYFGHFLGAHEGLVGLIKSRSGSSVSTIEKASLAFIVVTTWIVAVVNPSILG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHH
MIETMGAPMIAAILFLMPVFAMNKVPAMAKYKTSAPVQIFTALCGLAAISSVIYGAL
HHHHHCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTTTSSANAVTDTSKFNYKDFTWCLSLFGTAVGAGVLFLPIKAGAGGFWPLVILALIAA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHH
PMTWFAHKSLARFVLSSKNPEADITDTVEEHFGKTGANLITFAYFFAIYPIVLIYGVGIT
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
NTVDSFLVNQMGMESIPRPLLSGALILAMTAGVVFGKELMLKATSAMVYPLVFILLALSF
HHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLVPDWNTSMMETSPEWSAMPSIIWLAIPIIVFSFNHSPIISQFSKEQRRVYGEDAVKKT
HCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
DAITGGAAMMLMGFVMFFVFSVVLSLSPEQLATAQSQNISVLSYLANVHESPLISYMGPL
HCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHH
VAFAAITSSYFGHFLGAHEGLVGLIKSRSGSSVSTIEKASLAFIVVTTWIVAVVNPSILG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHH
MIETMGAPMIAAILFLMPVFAMNKVPAMAKYKTSAPVQIFTALCGLAAISSVIYGAL
HHHHHCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]