Click here to switch to the map view.

The map label for this gene is hscA [H]

Identifier: 218709775

GI number: 218709775

Start: 1912815

End: 1914794

Strand: Direct

Name: hscA [H]

Synonym: VS_1787

Alternate gene names: 218709775

Gene position: 1912815-1914794 (Clockwise)

Preceding gene: 218709774

Following gene: 218709776

Centisome position: 57.98

GC content: 48.99

Gene sequence:

>1980_bases
ATGGAACACCAAACTCAGCCATCTGCACAGACGCATTCACAAGAGCTATCTTCTCAAGAGCAACAGCAAGCGCCTAAGTT
CAGTGTCGGTATCGATTTAGGTACTACACACTGTGTTTTGTCTTTCATCGACACAACAAATGAAGACGCTCGCGTTGAGG
TGATGCCAATCCCTCAATTGACGGCTCCAGGTACCGTAGAAACTCGCAGCCAACTTGGCTCGTTCCTATACCAGCCGCAC
GAACATGAAATGAATGCGGGCTCTCGCGTTCTTCCTTGGTCTTCTGAACCTAAAGCGCTAGTCGGTGCGATTGCTCGTAA
CCTAGGTTCGAAAACCCCTATCCGTTTGGTAGCAAGTGCAAAATCTTGGCTATGCCACGGTGGTGTTAACCGTCGTGATG
CGTTCCTTCCAGCAGGCAGCCCTGAAGAAGTTGAAAAGGTATCTCCGCTTAAGACAACTGAGTTGTACCTTGAGCACCTT
AAAGATGCTTGGAACCACGCTAACCCAGAACACAAACTGGCAGACCAAGATGTCACGATCACGGTTCCAGCTTCGTTTGA
TCCTGCGGCTCGAGACCTAACGGCTGAAGCTGCGCGTAATGTTGGTTTTACTCACCTAACGCTTCTTGAAGAGCCACAAG
CAGCTCTTTACAGCTGGATTGATAACAGCAACGATACTTGGCGCGATGAAGTGAACGTTGGTGACATCGTTCTAGTTGTC
GATATCGGTGGTGGTACAACTGACCTTTCGTTAGTTGAAGTAACACAAGACGAAGGCAACCTAAGTCTGAACCGTATCGC
AGTAGGTGAACATATCCTACTTGGCGGCGACAACATGGACTTAGCGCTCGCTTACCGCCTGAAAATGAAGCTGGCTCAAG
AAGGCAAAGAACTGGCTCCTTGGCAGGTTCAAGCGATGACTCATGCGTGTCGTGATGCGAAAGAAGCATTGCTAAATGAT
GCTGAACTTCAATCTGTGCCCATCGTTGTTCCAAGCCGCGGCTCTAAGCTACTTGGCGCAACACTGAAAACAGAACTGAC
TCAGCAAGAAGTACAACAAACATTGGTTGATGGCTTCTTCCCACAAGTCGCTGTAACGGCTCACCCAGTACAGAAAACTC
GTGGTGCACTGACTCAAATGGGTCTACCTTACGCTCAAGACGCAGGTATTACTCGTCACATTGCTGCATTCCTTTCTAAG
CAAGCCAATGCGCTTTCTGGAAATAGTGAAACCGCTCAGCAAGATTTCAACCCGTTTGCAAACATGCCCGGTATGCCCGG
TACAGAAGCGCAAGGGTCAGAAGCGCCAGCGGCAGACTTCATCAAACCAACAGCGGTACTGTTCAATGGTGGTGTTCTAA
AATCTAACCTACTTGCTGATCGTCTTTCAGACACGATCAATGAATGGCTAATTAATGCAGACGCAGAATTCGCTAAACAG
CTTTCAGGCCTAGACTTAGACCTAGCGGTTGCAAGTGGCGCTTCATACTACGGCGCAGTTCGTCGTGGCCAAGGCGTTCG
TATCCGCGGTGGTATCGCTTCTTCTTATTACGTAGGAATTGAAAGCGCGATGCCAGCTATCCCAGGTATGGCTCCTCCAA
TGGAAGCACTGTGTGTTGCACCATTTGGCATGGAAGAAGGCTCAAGCGTTCAAGTTCCGAGTCAAGAGTTTGGTCTAGTG
ATTGGCCAGCCAGTACACTTCCAATTCTTCGGTTCAACAACACGTCGTGAAGACCAAGCAGGTACGCACCTTGATCACTG
GGCTCCAGAAGATCTTGATGAGCTTCCTGAAATCCAAGTGACACTGCCTGTTTCTGAAGGTCGTCGCGAAGGTGAAGTGG
TTCCGGTGACTTTGGCGTCTCGTGTTACTGAATTAGGCACGTTATACCTAGAAGCGATTGCCACTGACAATGGTCAGAAA
TGGCATGTTGAGTTCGACGTTCGTGAAGACTCGAATAACGACTCAAACGTAGAAGCATAA

Upstream 100 bases:

>100_bases
CATTGGTTCACAAAGGTTGGAAAGCAACTGACATGAACCTGCCTAAGCTTGCTGAGAACTACGATGCATCTGTGATTGCA
CCGGCAGAGGTGGAGCTATA

Downstream 100 bases:

>100_bases
TGAATCAACGGCACCTTAGCGGGTGCCGTTACTTTATCAATGCGATTCCCTAGCCCTGTATTAAAAGCATTCCAAAGACA
ATAATAAGACCAAAATTATC

Product: DnaK-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MEHQTQPSAQTHSQELSSQEQQQAPKFSVGIDLGTTHCVLSFIDTTNEDARVEVMPIPQLTAPGTVETRSQLGSFLYQPH
EHEMNAGSRVLPWSSEPKALVGAIARNLGSKTPIRLVASAKSWLCHGGVNRRDAFLPAGSPEEVEKVSPLKTTELYLEHL
KDAWNHANPEHKLADQDVTITVPASFDPAARDLTAEAARNVGFTHLTLLEEPQAALYSWIDNSNDTWRDEVNVGDIVLVV
DIGGGTTDLSLVEVTQDEGNLSLNRIAVGEHILLGGDNMDLALAYRLKMKLAQEGKELAPWQVQAMTHACRDAKEALLND
AELQSVPIVVPSRGSKLLGATLKTELTQQEVQQTLVDGFFPQVAVTAHPVQKTRGALTQMGLPYAQDAGITRHIAAFLSK
QANALSGNSETAQQDFNPFANMPGMPGTEAQGSEAPAADFIKPTAVLFNGGVLKSNLLADRLSDTINEWLINADAEFAKQ
LSGLDLDLAVASGASYYGAVRRGQGVRIRGGIASSYYVGIESAMPAIPGMAPPMEALCVAPFGMEEGSSVQVPSQEFGLV
IGQPVHFQFFGSTTRREDQAGTHLDHWAPEDLDELPEIQVTLPVSEGRREGEVVPVTLASRVTELGTLYLEAIATDNGQK
WHVEFDVREDSNNDSNVEA

Sequences:

>Translated_659_residues
MEHQTQPSAQTHSQELSSQEQQQAPKFSVGIDLGTTHCVLSFIDTTNEDARVEVMPIPQLTAPGTVETRSQLGSFLYQPH
EHEMNAGSRVLPWSSEPKALVGAIARNLGSKTPIRLVASAKSWLCHGGVNRRDAFLPAGSPEEVEKVSPLKTTELYLEHL
KDAWNHANPEHKLADQDVTITVPASFDPAARDLTAEAARNVGFTHLTLLEEPQAALYSWIDNSNDTWRDEVNVGDIVLVV
DIGGGTTDLSLVEVTQDEGNLSLNRIAVGEHILLGGDNMDLALAYRLKMKLAQEGKELAPWQVQAMTHACRDAKEALLND
AELQSVPIVVPSRGSKLLGATLKTELTQQEVQQTLVDGFFPQVAVTAHPVQKTRGALTQMGLPYAQDAGITRHIAAFLSK
QANALSGNSETAQQDFNPFANMPGMPGTEAQGSEAPAADFIKPTAVLFNGGVLKSNLLADRLSDTINEWLINADAEFAKQ
LSGLDLDLAVASGASYYGAVRRGQGVRIRGGIASSYYVGIESAMPAIPGMAPPMEALCVAPFGMEEGSSVQVPSQEFGLV
IGQPVHFQFFGSTTRREDQAGTHLDHWAPEDLDELPEIQVTLPVSEGRREGEVVPVTLASRVTELGTLYLEAIATDNGQK
WHVEFDVREDSNNDSNVEA
>Mature_659_residues
MEHQTQPSAQTHSQELSSQEQQQAPKFSVGIDLGTTHCVLSFIDTTNEDARVEVMPIPQLTAPGTVETRSQLGSFLYQPH
EHEMNAGSRVLPWSSEPKALVGAIARNLGSKTPIRLVASAKSWLCHGGVNRRDAFLPAGSPEEVEKVSPLKTTELYLEHL
KDAWNHANPEHKLADQDVTITVPASFDPAARDLTAEAARNVGFTHLTLLEEPQAALYSWIDNSNDTWRDEVNVGDIVLVV
DIGGGTTDLSLVEVTQDEGNLSLNRIAVGEHILLGGDNMDLALAYRLKMKLAQEGKELAPWQVQAMTHACRDAKEALLND
AELQSVPIVVPSRGSKLLGATLKTELTQQEVQQTLVDGFFPQVAVTAHPVQKTRGALTQMGLPYAQDAGITRHIAAFLSK
QANALSGNSETAQQDFNPFANMPGMPGTEAQGSEAPAADFIKPTAVLFNGGVLKSNLLADRLSDTINEWLINADAEFAKQ
LSGLDLDLAVASGASYYGAVRRGQGVRIRGGIASSYYVGIESAMPAIPGMAPPMEALCVAPFGMEEGSSVQVPSQEFGLV
IGQPVHFQFFGSTTRREDQAGTHLDHWAPEDLDELPEIQVTLPVSEGRREGEVVPVTLASRVTELGTLYLEAIATDNGQK
WHVEFDVREDSNNDSNVEA

Specific function: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by hscB [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

None

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 320 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stati

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126
- InterPro:   IPR010236 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 71208; Mature: 71208

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00297 HSP70_1 ; PS00329 HSP70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHQTQPSAQTHSQELSSQEQQQAPKFSVGIDLGTTHCVLSFIDTTNEDARVEVMPIPQL
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEEECCCC
TAPGTVETRSQLGSFLYQPHEHEMNAGSRVLPWSSEPKALVGAIARNLGSKTPIRLVASA
CCCCCHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCCEEEEECH
KSWLCHGGVNRRDAFLPAGSPEEVEKVSPLKTTELYLEHLKDAWNHANPEHKLADQDVTI
HHHHHCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
TVPASFDPAARDLTAEAARNVGFTHLTLLEEPQAALYSWIDNSNDTWRDEVNVGDIVLVV
EECCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCEEEEE
DIGGGTTDLSLVEVTQDEGNLSLNRIAVGEHILLGGDNMDLALAYRLKMKLAQEGKELAP
ECCCCCCCEEEEEEECCCCCEEEEEEEECCEEEECCCCCCEEEHHHHHHHHHHCCCCCCC
WQVQAMTHACRDAKEALLNDAELQSVPIVVPSRGSKLLGATLKTELTQQEVQQTLVDGFF
CHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCC
PQVAVTAHPVQKTRGALTQMGLPYAQDAGITRHIAAFLSKQANALSGNSETAQQDFNPFA
CCEEEEECCHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHH
NMPGMPGTEAQGSEAPAADFIKPTAVLFNGGVLKSNLLADRLSDTINEWLINADAEFAKQ
CCCCCCCCCCCCCCCCHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHEECCCHHHHHH
LSGLDLDLAVASGASYYGAVRRGQGVRIRGGIASSYYVGIESAMPAIPGMAPPMEALCVA
HCCCCEEEEEECCCHHHHHHHCCCCEEEECCCCCEEEEEHHHHCCCCCCCCCCHHHHEEC
PFGMEEGSSVQVPSQEFGLVIGQPVHFQFFGSTTRREDQAGTHLDHWAPEDLDELPEIQV
CCCCCCCCEEECCHHHCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCEEE
TLPVSEGRREGEVVPVTLASRVTELGTLYLEAIATDNGQKWHVEFDVREDSNNDSNVEA
EEEHHCCCCCCCEEEEEHHHHHHHHHHHHEEEEECCCCCEEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MEHQTQPSAQTHSQELSSQEQQQAPKFSVGIDLGTTHCVLSFIDTTNEDARVEVMPIPQL
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEEECCCC
TAPGTVETRSQLGSFLYQPHEHEMNAGSRVLPWSSEPKALVGAIARNLGSKTPIRLVASA
CCCCCHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCCEEEEECH
KSWLCHGGVNRRDAFLPAGSPEEVEKVSPLKTTELYLEHLKDAWNHANPEHKLADQDVTI
HHHHHCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
TVPASFDPAARDLTAEAARNVGFTHLTLLEEPQAALYSWIDNSNDTWRDEVNVGDIVLVV
EECCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCEEEEE
DIGGGTTDLSLVEVTQDEGNLSLNRIAVGEHILLGGDNMDLALAYRLKMKLAQEGKELAP
ECCCCCCCEEEEEEECCCCCEEEEEEEECCEEEECCCCCCEEEHHHHHHHHHHCCCCCCC
WQVQAMTHACRDAKEALLNDAELQSVPIVVPSRGSKLLGATLKTELTQQEVQQTLVDGFF
CHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCC
PQVAVTAHPVQKTRGALTQMGLPYAQDAGITRHIAAFLSKQANALSGNSETAQQDFNPFA
CCEEEEECCHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHH
NMPGMPGTEAQGSEAPAADFIKPTAVLFNGGVLKSNLLADRLSDTINEWLINADAEFAKQ
CCCCCCCCCCCCCCCCHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHEECCCHHHHHH
LSGLDLDLAVASGASYYGAVRRGQGVRIRGGIASSYYVGIESAMPAIPGMAPPMEALCVA
HCCCCEEEEEECCCHHHHHHHCCCCEEEECCCCCEEEEEHHHHCCCCCCCCCCHHHHEEC
PFGMEEGSSVQVPSQEFGLVIGQPVHFQFFGSTTRREDQAGTHLDHWAPEDLDELPEIQV
CCCCCCCCEEECCHHHCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCEEE
TLPVSEGRREGEVVPVTLASRVTELGTLYLEAIATDNGQKWHVEFDVREDSNNDSNVEA
EEEHHCCCCCCCEEEEEHHHHHHHHHHHHEEEEECCCCCEEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA