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The map label for this gene is hcpC [H]

Identifier: 218709734

GI number: 218709734

Start: 1869209

End: 1870216

Strand: Direct

Name: hcpC [H]

Synonym: VS_1745

Alternate gene names: 218709734

Gene position: 1869209-1870216 (Clockwise)

Preceding gene: 218709733

Following gene: 218709736

Centisome position: 56.65

GC content: 41.17

Gene sequence:

>1008_bases
ATGATAAAACAAAGTTGTACTTTTTTAACGTCACTGTCGCTGCTGCTATCCGCTAGCACTTTTGCATACGATCTTGAGAT
AGAAGCTTTTGAAGGCGAAGAACTCGCACTTTTAAAGAACGCAGAAACGTCTAGCGATAACGAATTGCTAATGCAGGCTG
CTAACCTTTTAATTGAAGATTCAATGTATGAAGAGAACTTACAACGCGGATATGAGTACATGAATCAAGTAGCGGAATCT
GGTGAGGTAAAAGCGATGATTACCTTGGCAGATAATTATTACTACGAAGAGCAATACGAAAAAGCACTGGCTTGGTACCA
CAAAGCTGAAACCAGCAAAGACCCTTATGTGCTCTACTCATTAGGCGTAATGTATTTTGATGGTGAAGGTACACCTATCG
ACCTAAAGAAAGGCAACGATTATTACCTAGCTTCTGCAAAAGCGGGGTATTCTGACGCTATGTATCAACTCGCATTTTCA
TACGATGAAGGTCAAGGCGTCACTCAAGACTTCTCCAAATCTGCGTATTGGTTTGAGCAATCGGCTAACTTAGGCGATGC
AAGTGCTATGTACAATTTGGGTATTTCTTACCTAAATGGACAAGGCGTTGAAAAGAGTTGCTCTAAAGCGATGCAATTAT
TTAGCAAAGCCATTGAAGAAGATGAACATACACTTTCTTATGTGAAGATGGGTGATATTTACTCTTCTACGCGATACAAA
AAACCGTGTGGTTTCAAAACTACAGACGCAAAAAAAGCATTAGAGTATTACACTCACGCCGCAATGCAGGGCAACGATTA
TGGTCAATATTCCGTTGGTTACGCCTACCGTAATGGTCACGGTACATGGAGCGATTTTGTTAAAGCGCTAGCATGGTTTG
AAGTCGCACAGGAATACGGAAACTCGGATGCAGAGAAAGAGATAATCGACGTGAAACAGTACATGTCGAAAGAAAACATT
GCCGCAGCTGCGCAGCTTAAAGACTCTTTAATCGAAGATATCTGGTAA

Upstream 100 bases:

>100_bases
TTGTCGTAAATTCGGTTTTCGATATCCCGAAATTTCCTTTATTTTCAAAGCTGTTTTGTTATATTCATGTGAAACATTAC
TAATATAAGAAATGGCTTAA

Downstream 100 bases:

>100_bases
GGATAGTAACGACTCTAATTGTCATGGACTAGAACACTTCTATCCAATTACCCGTTAGAGATCGGTTTATTGTAACAGCC
TCAAAACTAAGGCCTCACAC

Product: hypothetical protein

Products: NA

Alternate protein names: Cysteine-rich protein C [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MIKQSCTFLTSLSLLLSASTFAYDLEIEAFEGEELALLKNAETSSDNELLMQAANLLIEDSMYEENLQRGYEYMNQVAES
GEVKAMITLADNYYYEEQYEKALAWYHKAETSKDPYVLYSLGVMYFDGEGTPIDLKKGNDYYLASAKAGYSDAMYQLAFS
YDEGQGVTQDFSKSAYWFEQSANLGDASAMYNLGISYLNGQGVEKSCSKAMQLFSKAIEEDEHTLSYVKMGDIYSSTRYK
KPCGFKTTDAKKALEYYTHAAMQGNDYGQYSVGYAYRNGHGTWSDFVKALAWFEVAQEYGNSDAEKEIIDVKQYMSKENI
AAAAQLKDSLIEDIW

Sequences:

>Translated_335_residues
MIKQSCTFLTSLSLLLSASTFAYDLEIEAFEGEELALLKNAETSSDNELLMQAANLLIEDSMYEENLQRGYEYMNQVAES
GEVKAMITLADNYYYEEQYEKALAWYHKAETSKDPYVLYSLGVMYFDGEGTPIDLKKGNDYYLASAKAGYSDAMYQLAFS
YDEGQGVTQDFSKSAYWFEQSANLGDASAMYNLGISYLNGQGVEKSCSKAMQLFSKAIEEDEHTLSYVKMGDIYSSTRYK
KPCGFKTTDAKKALEYYTHAAMQGNDYGQYSVGYAYRNGHGTWSDFVKALAWFEVAQEYGNSDAEKEIIDVKQYMSKENI
AAAAQLKDSLIEDIW
>Mature_335_residues
MIKQSCTFLTSLSLLLSASTFAYDLEIEAFEGEELALLKNAETSSDNELLMQAANLLIEDSMYEENLQRGYEYMNQVAES
GEVKAMITLADNYYYEEQYEKALAWYHKAETSKDPYVLYSLGVMYFDGEGTPIDLKKGNDYYLASAKAGYSDAMYQLAFS
YDEGQGVTQDFSKSAYWFEQSANLGDASAMYNLGISYLNGQGVEKSCSKAMQLFSKAIEEDEHTLSYVKMGDIYSSTRYK
KPCGFKTTDAKKALEYYTHAAMQGNDYGQYSVGYAYRNGHGTWSDFVKALAWFEVAQEYGNSDAEKEIIDVKQYMSKENI
AAAAQLKDSLIEDIW

Specific function: May hydrolyze 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives [H]

COG id: COG0790

COG function: function code R; FOG: TPR repeat, SEL1 subfamily

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 7 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI151301150, Length=283, Percent_Identity=25.4416961130742, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI19923669, Length=162, Percent_Identity=30.2469135802469, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87081769, Length=129, Percent_Identity=34.8837209302326, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355295, Length=270, Percent_Identity=27.037037037037, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006597
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF08238 Sel1 [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 37831; Mature: 37831

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKQSCTFLTSLSLLLSASTFAYDLEIEAFEGEELALLKNAETSSDNELLMQAANLLIED
CCCCHHHHHHHHHHHHHHHHEEEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHH
SMYEENLQRGYEYMNQVAESGEVKAMITLADNYYYEEQYEKALAWYHKAETSKDPYVLYS
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
LGVMYFDGEGTPIDLKKGNDYYLASAKAGYSDAMYQLAFSYDEGQGVTQDFSKSAYWFEQ
EEEEEECCCCCEEEEECCCCEEEEECCCCCHHHHHHHEEECCCCCCCHHHHHCCHHHHHC
SANLGDASAMYNLGISYLNGQGVEKSCSKAMQLFSKAIEEDEHTLSYVKMGDIYSSTRYK
CCCCCCHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHEEECCHHHCCCCC
KPCGFKTTDAKKALEYYTHAAMQGNDYGQYSVGYAYRNGHGTWSDFVKALAWFEVAQEYG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHC
NSDAEKEIIDVKQYMSKENIAAAAQLKDSLIEDIW
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKQSCTFLTSLSLLLSASTFAYDLEIEAFEGEELALLKNAETSSDNELLMQAANLLIED
CCCCHHHHHHHHHHHHHHHHEEEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHH
SMYEENLQRGYEYMNQVAESGEVKAMITLADNYYYEEQYEKALAWYHKAETSKDPYVLYS
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
LGVMYFDGEGTPIDLKKGNDYYLASAKAGYSDAMYQLAFSYDEGQGVTQDFSKSAYWFEQ
EEEEEECCCCCEEEEECCCCEEEEECCCCCHHHHHHHEEECCCCCCCHHHHHCCHHHHHC
SANLGDASAMYNLGISYLNGQGVEKSCSKAMQLFSKAIEEDEHTLSYVKMGDIYSSTRYK
CCCCCCHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHEEECCHHHCCCCC
KPCGFKTTDAKKALEYYTHAAMQGNDYGQYSVGYAYRNGHGTWSDFVKALAWFEVAQEYG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHC
NSDAEKEIIDVKQYMSKENIAAAAQLKDSLIEDIW
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]