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The map label for this gene is ydcR [H]

Identifier: 218709712

GI number: 218709712

Start: 1849234

End: 1850616

Strand: Direct

Name: ydcR [H]

Synonym: VS_1723

Alternate gene names: 218709712

Gene position: 1849234-1850616 (Clockwise)

Preceding gene: 218709709

Following gene: 218709713

Centisome position: 56.05

GC content: 46.13

Gene sequence:

>1383_bases
ATGAGCATCTACAGAAAGCTAGCCAATCAGTTTATTGATGAGATTGAAACGGGGAAAAGACCCGAAGGTGGACGCATGCC
TTCGCTGCGTCAATTAGCTAAACAACAAGCCATCAGCATGTCGACCGTGGTGAGCTGCTACCAAGAACTCGAATCACAAG
GCTGGATACACTCTCGACCGCAAGCAGGGTATTTTGTTTCTCCTCATAAACCTGCTCGTTCAACCCCAGAGTGGGCACAG
TTTGAAAGTAAAGTGTCGAGCGTCAAGCTAACCTCATCGACTCACAACTCAATCAATGGATCTTTAGGGGTGTCTAGCAC
CGCCAATGATGAACAGTCGATTGTTGAACTGGAACGCAGTTTTCGCCGCGCTATTCGGCGTATGAGCAGCAGGCTAAACC
ATTACCCAGATACACAAGGTGAGCCAATGTTACGTCAGGCATTATCCACTCACTTTGCCAAGCTCGATGTACACTTTTCA
CCTGAAGAGATGGTGATTACTGCAGGCTGTATGTCTGCGATTAAGGCTGCACTTGAATCGTGCACCAAAGAAGGCGACAC
CATCGCGATTAGTTCACCTTGTTTCAACGGCATTCTGGAGTTGCTCGGAAAGATGTCGCGACAAATCATCGAGATCCCAT
CTCTGGATGACGGTATCGACTTGCAACAATTGGAAGCGCATTTGAAGAATAGACAAGTCGATGCCGCGATTTTTTGTACC
TCTCATATGAACCCTCAAGGGATCAACATGTCGGCTAGTCAAAAACAAAAGCTTGCTGAATTAGCGAATCACTATCAAGT
ACCGATCATTGAAGATGATGTGTATCTGGAACTTTCTTATTCCTCACACACTCCACTCCCCGCGAAATACTACGACAAAG
GCGGCTATGTACTATGGTGTGGTTCAATATCGAAAAGCTTGTCACCGAGTTACCGATTAGGATGGTGCTTACCAGGGAGG
TTCATTAACGAATACAAGGCTCAGTTTTCTGCTGCAAGCTATGGCGTCGCCCTACCCACTCAGCTTGCAGTTGCTGACTT
TATCGAATCTGGTCAATACGCAAAACACGTTAGAAGAAGGTGTACTCAGCTTCTCTCTTTGCGCCAGCAATACCTAAGTT
ATTTGGCTCAGCACCTTCCTCAAGGAGTAAAGATAAGTAACCCGCAAGGTGGCATGGTACTTTGGCTACAAATACCAAAT
TTGAACCAATCAAGCTTTGCTCAGGCAGTTGCCGACCACAACATTGATATTAGGCTTGGACACCTGTTCAGCACTCTCGA
CCTTTGCAGCAATTGCTTACGCATCAATATTGGGTATTCGTTAGAGGGTGAAACTAAGCAGCAATTGGATGCCTTAATTG
AGCTTATCCACATTCACAGCTAA

Upstream 100 bases:

>100_bases
GACCCCTCCTTTGTTTTGAATGAGTATCCCTTGATCAATAAAACCAGTACAGATACAATTTTTACAATAAAAACCAGTAC
AGTTAACAACGGTCGTGACC

Downstream 100 bases:

>100_bases
CAGCCCGGAGCCTTTCAAAATCAGCTTTTTAAAAGCCTTTCGAACACCGAATTTTAATAGCCTTTTGTCATAAAAAAGAA
GGCTATTATTCCTATCTTGA

Product: potential transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MSIYRKLANQFIDEIETGKRPEGGRMPSLRQLAKQQAISMSTVVSCYQELESQGWIHSRPQAGYFVSPHKPARSTPEWAQ
FESKVSSVKLTSSTHNSINGSLGVSSTANDEQSIVELERSFRRAIRRMSSRLNHYPDTQGEPMLRQALSTHFAKLDVHFS
PEEMVITAGCMSAIKAALESCTKEGDTIAISSPCFNGILELLGKMSRQIIEIPSLDDGIDLQQLEAHLKNRQVDAAIFCT
SHMNPQGINMSASQKQKLAELANHYQVPIIEDDVYLELSYSSHTPLPAKYYDKGGYVLWCGSISKSLSPSYRLGWCLPGR
FINEYKAQFSAASYGVALPTQLAVADFIESGQYAKHVRRRCTQLLSLRQQYLSYLAQHLPQGVKISNPQGGMVLWLQIPN
LNQSSFAQAVADHNIDIRLGHLFSTLDLCSNCLRINIGYSLEGETKQQLDALIELIHIHS

Sequences:

>Translated_460_residues
MSIYRKLANQFIDEIETGKRPEGGRMPSLRQLAKQQAISMSTVVSCYQELESQGWIHSRPQAGYFVSPHKPARSTPEWAQ
FESKVSSVKLTSSTHNSINGSLGVSSTANDEQSIVELERSFRRAIRRMSSRLNHYPDTQGEPMLRQALSTHFAKLDVHFS
PEEMVITAGCMSAIKAALESCTKEGDTIAISSPCFNGILELLGKMSRQIIEIPSLDDGIDLQQLEAHLKNRQVDAAIFCT
SHMNPQGINMSASQKQKLAELANHYQVPIIEDDVYLELSYSSHTPLPAKYYDKGGYVLWCGSISKSLSPSYRLGWCLPGR
FINEYKAQFSAASYGVALPTQLAVADFIESGQYAKHVRRRCTQLLSLRQQYLSYLAQHLPQGVKISNPQGGMVLWLQIPN
LNQSSFAQAVADHNIDIRLGHLFSTLDLCSNCLRINIGYSLEGETKQQLDALIELIHIHS
>Mature_459_residues
SIYRKLANQFIDEIETGKRPEGGRMPSLRQLAKQQAISMSTVVSCYQELESQGWIHSRPQAGYFVSPHKPARSTPEWAQF
ESKVSSVKLTSSTHNSINGSLGVSSTANDEQSIVELERSFRRAIRRMSSRLNHYPDTQGEPMLRQALSTHFAKLDVHFSP
EEMVITAGCMSAIKAALESCTKEGDTIAISSPCFNGILELLGKMSRQIIEIPSLDDGIDLQQLEAHLKNRQVDAAIFCTS
HMNPQGINMSASQKQKLAELANHYQVPIIEDDVYLELSYSSHTPLPAKYYDKGGYVLWCGSISKSLSPSYRLGWCLPGRF
INEYKAQFSAASYGVALPTQLAVADFIESGQYAKHVRRRCTQLLSLRQQYLSYLAQHLPQGVKISNPQGGMVLWLQIPNL
NQSSFAQAVADHNIDIRLGHLFSTLDLCSNCLRINIGYSLEGETKQQLDALIELIHIHS

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=306, Percent_Identity=24.5098039215686, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI33469970, Length=306, Percent_Identity=24.5098039215686, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4507369, Length=262, Percent_Identity=23.6641221374046, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787710, Length=476, Percent_Identity=32.563025210084, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1790797, Length=470, Percent_Identity=28.936170212766, Blast_Score=216, Evalue=3e-57,
Organism=Drosophila melanogaster, GI21356535, Length=352, Percent_Identity=25.8522727272727, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51323; Mature: 51192

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIYRKLANQFIDEIETGKRPEGGRMPSLRQLAKQQAISMSTVVSCYQELESQGWIHSRP
CHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QAGYFVSPHKPARSTPEWAQFESKVSSVKLTSSTHNSINGSLGVSSTANDEQSIVELERS
CCCEEECCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
FRRAIRRMSSRLNHYPDTQGEPMLRQALSTHFAKLDVHFSPEEMVITAGCMSAIKAALES
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEEEECCCHHEEHHHHHHHHHHHHHH
CTKEGDTIAISSPCFNGILELLGKMSRQIIEIPSLDDGIDLQQLEAHLKNRQVDAAIFCT
HHCCCCEEEECCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHCCCCCEEEEEE
SHMNPQGINMSASQKQKLAELANHYQVPIIEDDVYLELSYSSHTPLPAKYYDKGGYVLWC
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCEEEEEECCCCCCCCHHEECCCCEEEEE
GSISKSLSPSYRLGWCLPGRFINEYKAQFSAASYGVALPTQLAVADFIESGQYAKHVRRR
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHH
CTQLLSLRQQYLSYLAQHLPQGVKISNPQGGMVLWLQIPNLNQSSFAQAVADHNIDIRLG
HHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEHH
HLFSTLDLCSNCLRINIGYSLEGETKQQLDALIELIHIHS
HHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIYRKLANQFIDEIETGKRPEGGRMPSLRQLAKQQAISMSTVVSCYQELESQGWIHSRP
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QAGYFVSPHKPARSTPEWAQFESKVSSVKLTSSTHNSINGSLGVSSTANDEQSIVELERS
CCCEEECCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
FRRAIRRMSSRLNHYPDTQGEPMLRQALSTHFAKLDVHFSPEEMVITAGCMSAIKAALES
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEEEECCCHHEEHHHHHHHHHHHHHH
CTKEGDTIAISSPCFNGILELLGKMSRQIIEIPSLDDGIDLQQLEAHLKNRQVDAAIFCT
HHCCCCEEEECCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHCCCCCEEEEEE
SHMNPQGINMSASQKQKLAELANHYQVPIIEDDVYLELSYSSHTPLPAKYYDKGGYVLWC
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCEEEEEECCCCCCCCHHEECCCCEEEEE
GSISKSLSPSYRLGWCLPGRFINEYKAQFSAASYGVALPTQLAVADFIESGQYAKHVRRR
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHH
CTQLLSLRQQYLSYLAQHLPQGVKISNPQGGMVLWLQIPNLNQSSFAQAVADHNIDIRLG
HHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEHH
HLFSTLDLCSNCLRINIGYSLEGETKQQLDALIELIHIHS
HHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]