Click here to switch to the map view.

The map label for this gene is eamA [H]

Identifier: 218709711

GI number: 218709711

Start: 1848237

End: 1849241

Strand: Reverse

Name: eamA [H]

Synonym: VS_1722

Alternate gene names: 218709711

Gene position: 1849241-1848237 (Counterclockwise)

Preceding gene: 218709714

Following gene: 218709710

Centisome position: 56.05

GC content: 45.77

Gene sequence:

>1005_bases
ATGCTCATGGTCACGACCGTTGTTAACTGTACTGGTTTTTATTGTAAAAATTGTATCTGTACTGGTTTTATTGATCAAGG
GATACTCATTCAAAACAAAGGAGGGGTCAGTATGAAAAGAAATGATTTGTTGTTAGCGGTGTTCGTGATGGCAATTTGGG
GATTCAATTTCTCGATGATCAAAATGGGTGTAACCAATGTTCATCCGTTGTTGGCAACCGCCGCGCGTTTCTCGCTAGCG
GTGATTCCGGTGATATTTTTTGTAGCAAGACCGAATGTCGCGTGGCGTTATTTAGTGAGTTATGGCTTTGTGTTTGGTGT
GGGCATCTGGGGCATGGCTTCATGGTCAATCACCGCAGGGCTCTCATCGGGGCTTTCGTCGGTGTTGCTTTCAACCAATG
TGCTAATTGGTATGGCGGTTGGCGTGTGGGTTTTCAAAGAAAGTGCGTCGGTTCGCAAGTTAATGGGTGCGATGTTAGCC
ATGTGCGCGTTGGCGGTGCTGGTTTCCGCAGCAACGGGCAATGTCACTGTTAATGGCGTGATTCTTATTATGGTCGCAGC
GTGTAGTTGGACGTTAATGGGCGTGATTGTTAAAGCGTCTAAAACCACTCAGGCTTTTGCGTTTAACGTGTGGGGCATGC
TATTTGCGCCAGTTCCATTAGTGTTGTTTGCGGTGATGCTGCACGGTGACCAAATTATTTGGCAGGCGATAGAACAATGG
GATTGGAACGCAACGATTGCTGTGTTGTTTCAGGCTTACCCAACCACGCTATTCGGTTACTGGGTGTGGAATAAACTGTT
AATTCAATATCCGTTAAGCACGACAGCGCCGTTAACCTTGCTAGTACCTATATTCGCATTGATCAGTGGTTACTTTATGT
ATGACGAGGTGCTATCAGTCGCTCAAGTTGTGGCATCTGTACTGTTTCTAGTCGGTATAGGTTTGATAGTGAAGCCTGCT
AAGACAACCGTAAGACCTCTTAGGGAAATAAAGACGATTGATTGA

Upstream 100 bases:

>100_bases
TTGTTGTTTAGCTAATTGACGCAGCGAAGGCATGCGTCCACCTTCGGGTCTTTTCCCCGTTTCAATCTCATCAATAAACT
GATTGGCTAGCTTTCTGTAG

Downstream 100 bases:

>100_bases
GCGTTTTCTAAAAACACAGCAGAATAGCATTGTCGAAAGGATTGACTAATTCGAATTAAATTCTGAAATGATACAAATAT
CATATTTAATAATGGTTACT

Product: drug/metabolite transporter superfamily permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLMVTTVVNCTGFYCKNCICTGFIDQGILIQNKGGVSMKRNDLLLAVFVMAIWGFNFSMIKMGVTNVHPLLATAARFSLA
VIPVIFFVARPNVAWRYLVSYGFVFGVGIWGMASWSITAGLSSGLSSVLLSTNVLIGMAVGVWVFKESASVRKLMGAMLA
MCALAVLVSAATGNVTVNGVILIMVAACSWTLMGVIVKASKTTQAFAFNVWGMLFAPVPLVLFAVMLHGDQIIWQAIEQW
DWNATIAVLFQAYPTTLFGYWVWNKLLIQYPLSTTAPLTLLVPIFALISGYFMYDEVLSVAQVVASVLFLVGIGLIVKPA
KTTVRPLREIKTID

Sequences:

>Translated_334_residues
MLMVTTVVNCTGFYCKNCICTGFIDQGILIQNKGGVSMKRNDLLLAVFVMAIWGFNFSMIKMGVTNVHPLLATAARFSLA
VIPVIFFVARPNVAWRYLVSYGFVFGVGIWGMASWSITAGLSSGLSSVLLSTNVLIGMAVGVWVFKESASVRKLMGAMLA
MCALAVLVSAATGNVTVNGVILIMVAACSWTLMGVIVKASKTTQAFAFNVWGMLFAPVPLVLFAVMLHGDQIIWQAIEQW
DWNATIAVLFQAYPTTLFGYWVWNKLLIQYPLSTTAPLTLLVPIFALISGYFMYDEVLSVAQVVASVLFLVGIGLIVKPA
KTTVRPLREIKTID
>Mature_334_residues
MLMVTTVVNCTGFYCKNCICTGFIDQGILIQNKGGVSMKRNDLLLAVFVMAIWGFNFSMIKMGVTNVHPLLATAARFSLA
VIPVIFFVARPNVAWRYLVSYGFVFGVGIWGMASWSITAGLSSGLSSVLLSTNVLIGMAVGVWVFKESASVRKLMGAMLA
MCALAVLVSAATGNVTVNGVILIMVAACSWTLMGVIVKASKTTQAFAFNVWGMLFAPVPLVLFAVMLHGDQIIWQAIEQW
DWNATIAVLFQAYPTTLFGYWVWNKLLIQYPLSTTAPLTLLVPIFALISGYFMYDEVLSVAQVVASVLFLVGIGLIVKPA
KTTVRPLREIKTID

Specific function: May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O- acetyl-L-serine (OAS)), and for other amino acids and their metabolites [H]

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Escherichia coli, GI87081929, Length=282, Percent_Identity=30.1418439716312, Blast_Score=128, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 36337; Mature: 36337

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMVTTVVNCTGFYCKNCICTGFIDQGILIQNKGGVSMKRNDLLLAVFVMAIWGFNFSMI
CEEEEEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHH
KMGVTNVHPLLATAARFSLAVIPVIFFVARPNVAWRYLVSYGFVFGVGIWGMASWSITAG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSGLSSVLLSTNVLIGMAVGVWVFKESASVRKLMGAMLAMCALAVLVSAATGNVTVNGV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHH
ILIMVAACSWTLMGVIVKASKTTQAFAFNVWGMLFAPVPLVLFAVMLHGDQIIWQAIEQW
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
DWNATIAVLFQAYPTTLFGYWVWNKLLIQYPLSTTAPLTLLVPIFALISGYFMYDEVLSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQVVASVLFLVGIGLIVKPAKTTVRPLREIKTID
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLMVTTVVNCTGFYCKNCICTGFIDQGILIQNKGGVSMKRNDLLLAVFVMAIWGFNFSMI
CEEEEEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHH
KMGVTNVHPLLATAARFSLAVIPVIFFVARPNVAWRYLVSYGFVFGVGIWGMASWSITAG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSGLSSVLLSTNVLIGMAVGVWVFKESASVRKLMGAMLAMCALAVLVSAATGNVTVNGV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHH
ILIMVAACSWTLMGVIVKASKTTQAFAFNVWGMLFAPVPLVLFAVMLHGDQIIWQAIEQW
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
DWNATIAVLFQAYPTTLFGYWVWNKLLIQYPLSTTAPLTLLVPIFALISGYFMYDEVLSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQVVASVLFLVGIGLIVKPAKTTVRPLREIKTID
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 10844694 [H]