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The map label for this gene is cobT

Identifier: 218709691

GI number: 218709691

Start: 1827655

End: 1828683

Strand: Reverse

Name: cobT

Synonym: VS_1702

Alternate gene names: 218709691

Gene position: 1828683-1827655 (Counterclockwise)

Preceding gene: 218709692

Following gene: 218709690

Centisome position: 55.43

GC content: 47.72

Gene sequence:

>1029_bases
ATGTTAGATACCCAATACTCGCAGTACATCCAACACCGAATTGACCAAAAAACCAAGCCACTCGGTGCGCTTGGCTTACT
AGAAAAAGTCGCACATCAACTGGCATTGATTCAGAGCCAAGGCAAAGAAACTGCGGTTGAGCACATCGAATTGAATAAGC
CACGTATCATCATTTTTGCTGGCGACCATGGCATAGCAGATGAAGGTGTGAGTATTGCTCCAAGTGCCGTCACGCAACAG
ATGGTGTTGAACTTCTTAAGCGGTGGCGCAGCGATTAATTGCTTTTGTGCGGTAAACAACGTCGAAATTACAGTCGTGGA
CACTGGGATTTTGTTGCCTGTTGAATCTGACAGCGACATGTTGATTTCTCAGCGCTTAGGTACGCGAACCAATAACTTTG
CCAATGAAGCGGCAATGAGTTTAGAAACTGTTGAACGTGGGATTGAACTGGGAACTGAGCTTGTATCTAGAACCATTTCG
AATGGCACGAATATCATCATGTTTGGTGAAATGGGCATCGGCAATACCAGCAGCGCGTCTGCCATCTTAAGTGCGCTAGC
AAACCGAACTGCAGATGAGTGTGTTGGTTTAGGCACTGGTATCAACAATGAACAGCTTGCACGTAAAGTGGCGGTGGTTA
AGCAAGGTATTGCTCGTTGCATAAATCCTGACGCAAAAGAGGTGTTAAGCCAAGTCGGCGGTTATGAAATAGTTCAAATG
GTGGGGGGCTTCCTTGGCGCTTACGAAAACAGAACCCCTGTGTTGGTCGATGGTTTTATCGTGTCGGTTGCGGCGTATGT
CGCGACTCTAATTGAACCGAGTTGCCGTGATTACATGATCTTTGCTCATCGCTCTGAAGAGTCGGGGCACAAGATTCTAT
TAGAGCTGCTAGACGCTGAGCCACTGCTCGATCTTGGATTGAGATTGGGCGAGGGCACAGGTGCTGCGCTAGCTATGCCA
ATAATTCGTGCGGCGGCAGAGTTCTATAACAACATGGCGAGTTTTGCGAGTGCTGGAGTCACGGTTTAA

Upstream 100 bases:

>100_bases
TGTGTTCTCTGTTGCACGCCCTAAATAGTGTAACGATTTAGCTTAAGCAGAATCGCAGCCCTAGAAATCCATTACCTTAA
ATTTAAGTGTTCCTAAACTT

Downstream 100 bases:

>100_bases
TGAGTGATGCACCAAAAAGATCGTTGAAAGATAGCATCACATACCAATGGGAACTTTTTTCGTTGGCGATGGGTTTCTTT
TCTCGTTTGCCGATGCCGAA

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MLDTQYSQYIQHRIDQKTKPLGALGLLEKVAHQLALIQSQGKETAVEHIELNKPRIIIFAGDHGIADEGVSIAPSAVTQQ
MVLNFLSGGAAINCFCAVNNVEITVVDTGILLPVESDSDMLISQRLGTRTNNFANEAAMSLETVERGIELGTELVSRTIS
NGTNIIMFGEMGIGNTSSASAILSALANRTADECVGLGTGINNEQLARKVAVVKQGIARCINPDAKEVLSQVGGYEIVQM
VGGFLGAYENRTPVLVDGFIVSVAAYVATLIEPSCRDYMIFAHRSEESGHKILLELLDAEPLLDLGLRLGEGTGAALAMP
IIRAAAEFYNNMASFASAGVTV

Sequences:

>Translated_342_residues
MLDTQYSQYIQHRIDQKTKPLGALGLLEKVAHQLALIQSQGKETAVEHIELNKPRIIIFAGDHGIADEGVSIAPSAVTQQ
MVLNFLSGGAAINCFCAVNNVEITVVDTGILLPVESDSDMLISQRLGTRTNNFANEAAMSLETVERGIELGTELVSRTIS
NGTNIIMFGEMGIGNTSSASAILSALANRTADECVGLGTGINNEQLARKVAVVKQGIARCINPDAKEVLSQVGGYEIVQM
VGGFLGAYENRTPVLVDGFIVSVAAYVATLIEPSCRDYMIFAHRSEESGHKILLELLDAEPLLDLGLRLGEGTGAALAMP
IIRAAAEFYNNMASFASAGVTV
>Mature_342_residues
MLDTQYSQYIQHRIDQKTKPLGALGLLEKVAHQLALIQSQGKETAVEHIELNKPRIIIFAGDHGIADEGVSIAPSAVTQQ
MVLNFLSGGAAINCFCAVNNVEITVVDTGILLPVESDSDMLISQRLGTRTNNFANEAAMSLETVERGIELGTELVSRTIS
NGTNIIMFGEMGIGNTSSASAILSALANRTADECVGLGTGINNEQLARKVAVVKQGIARCINPDAKEVLSQVGGYEIVQM
VGGFLGAYENRTPVLVDGFIVSVAAYVATLIEPSCRDYMIFAHRSEESGHKILLELLDAEPLLDLGLRLGEGTGAALAMP
IIRAAAEFYNNMASFASAGVTV

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family

Homologues:

Organism=Escherichia coli, GI1788300, Length=348, Percent_Identity=35.3448275862069, Blast_Score=192, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBT_VIBSL (B7VPD7)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002417312.1
- GeneID:   7161270
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_1702
- HOGENOM:   HBG634399
- OMA:   NEMATFS
- ProtClustDB:   PRK00105
- HAMAP:   MF_00230
- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846
- Gene3D:   G3DSA:1.10.1610.10
- TIGRFAMs:   TIGR03160

Pfam domain/function: PF02277 DBI_PRT; SSF52733 NN:DBI_PRT

EC number: =2.4.2.21

Molecular weight: Translated: 36351; Mature: 36351

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: ACT_SITE 311-311

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDTQYSQYIQHRIDQKTKPLGALGLLEKVAHQLALIQSQGKETAVEHIELNKPRIIIFA
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEE
GDHGIADEGVSIAPSAVTQQMVLNFLSGGAAINCFCAVNNVEITVVDTGILLPVESDSDM
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEEECEEEEEECCCCCH
LISQRLGTRTNNFANEAAMSLETVERGIELGTELVSRTISNGTNIIMFGEMGIGNTSSAS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHH
AILSALANRTADECVGLGTGINNEQLARKVAVVKQGIARCINPDAKEVLSQVGGYEIVQM
HHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHH
VGGFLGAYENRTPVLVDGFIVSVAAYVATLIEPSCRDYMIFAHRSEESGHKILLELLDAE
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCC
PLLDLGLRLGEGTGAALAMPIIRAAAEFYNNMASFASAGVTV
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLDTQYSQYIQHRIDQKTKPLGALGLLEKVAHQLALIQSQGKETAVEHIELNKPRIIIFA
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEE
GDHGIADEGVSIAPSAVTQQMVLNFLSGGAAINCFCAVNNVEITVVDTGILLPVESDSDM
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEEECEEEEEECCCCCH
LISQRLGTRTNNFANEAAMSLETVERGIELGTELVSRTISNGTNIIMFGEMGIGNTSSAS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHH
AILSALANRTADECVGLGTGINNEQLARKVAVVKQGIARCINPDAKEVLSQVGGYEIVQM
HHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHH
VGGFLGAYENRTPVLVDGFIVSVAAYVATLIEPSCRDYMIFAHRSEESGHKILLELLDAE
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCC
PLLDLGLRLGEGTGAALAMPIIRAAAEFYNNMASFASAGVTV
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA