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The map label for this gene is cobU [H]

Identifier: 218709689

GI number: 218709689

Start: 1826222

End: 1826839

Strand: Reverse

Name: cobU [H]

Synonym: VS_1700

Alternate gene names: 218709689

Gene position: 1826839-1826222 (Counterclockwise)

Preceding gene: 218709690

Following gene: 218709688

Centisome position: 55.37

GC content: 45.63

Gene sequence:

>618_bases
ATGACAAACACGAATCAAGCTAATCAAATTAATCAAGTAAGTCAGCGAAATAGCCATCTGGTATTGGGTGGGGCTCGTTC
TGGTAAGTCTAGTTTTGCAGAACAACAGGCATTATGTGCGCTTGAAGCATGTTCAAATGGACGCCTCAACTATATTGCGA
CGGCCACTTATTTGGACGACGAAATGCGTGAGAGAATTGCGCATCATCAACAACGTCGTGGTGAGCTGTGGATTGAGCAT
GAAGCCCCTGTTGAATTAGCCGAAAAACTGCAGTCTTTTGATCAAAACGATGTGGTGATGATTGACTGCTTAACTTTGTG
GTTGAACAACATTATTTTTGAGTTGGGTGATGATGCGACCAATGAACAGGTTGAGGCCGTGGTCGAAGTTTTAGTGAAAA
GCGTAGAGCAAAGCCCGGCGCAAATTATCATGGTTTCTAACGAAGTCGGTTTAGGTGTGGTGCCGTTAGGTAAAGTATCG
CGCCTATTTGTCGACAATGCGGGTCGCATGAACCAAGCGCTAGCTCGCGTCGTTGAACGCGTTACGCTGGTTGCTGCAGG
ATTACCATTGAGCTTAAAGCCGTCGAGCTATTTGACTCAAAGCTCGACTCATAATTAG

Upstream 100 bases:

>100_bases
TACTGGCGACTGTTTGGGTGCGGCTCAACAGTTGATGGAGTTACTGATTTACCTTGTGTTCATTACTGCTTTTTACAACG
GTTTTTTATAACAGGTTCCT

Downstream 100 bases:

>100_bases
ATTGGTATCAAAGGTTAGTTGAACAAATGGAAAATGGAACAACCAAAAACATCTATCTACTAAGACATGGCAAAGTCGAA
GGCGAAGCGGCACTTAATGG

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTNTNQANQINQVSQRNSHLVLGGARSGKSSFAEQQALCALEACSNGRLNYIATATYLDDEMRERIAHHQQRRGELWIEH
EAPVELAEKLQSFDQNDVVMIDCLTLWLNNIIFELGDDATNEQVEAVVEVLVKSVEQSPAQIIMVSNEVGLGVVPLGKVS
RLFVDNAGRMNQALARVVERVTLVAAGLPLSLKPSSYLTQSSTHN

Sequences:

>Translated_205_residues
MTNTNQANQINQVSQRNSHLVLGGARSGKSSFAEQQALCALEACSNGRLNYIATATYLDDEMRERIAHHQQRRGELWIEH
EAPVELAEKLQSFDQNDVVMIDCLTLWLNNIIFELGDDATNEQVEAVVEVLVKSVEQSPAQIIMVSNEVGLGVVPLGKVS
RLFVDNAGRMNQALARVVERVTLVAAGLPLSLKPSSYLTQSSTHN
>Mature_204_residues
TNTNQANQINQVSQRNSHLVLGGARSGKSSFAEQQALCALEACSNGRLNYIATATYLDDEMRERIAHHQQRRGELWIEHE
APVELAEKLQSFDQNDVVMIDCLTLWLNNIIFELGDDATNEQVEAVVEVLVKSVEQSPAQIIMVSNEVGLGVVPLGKVSR
LFVDNAGRMNQALARVVERVTLVAAGLPLSLKPSSYLTQSSTHN

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=184, Percent_Identity=38.5869565217391, Blast_Score=121, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 22569; Mature: 22438

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTNQANQINQVSQRNSHLVLGGARSGKSSFAEQQALCALEACSNGRLNYIATATYLDD
CCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHH
EMRERIAHHQQRRGELWIEHEAPVELAEKLQSFDQNDVVMIDCLTLWLNNIIFELGDDAT
HHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCC
NEQVEAVVEVLVKSVEQSPAQIIMVSNEVGLGVVPLGKVSRLFVDNAGRMNQALARVVER
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEECHHHHHHHHHCCCCHHHHHHHHHHHH
VTLVAAGLPLSLKPSSYLTQSSTHN
HHHHHCCCCCEECCHHHHCCCCCCC
>Mature Secondary Structure 
TNTNQANQINQVSQRNSHLVLGGARSGKSSFAEQQALCALEACSNGRLNYIATATYLDD
CCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHH
EMRERIAHHQQRRGELWIEHEAPVELAEKLQSFDQNDVVMIDCLTLWLNNIIFELGDDAT
HHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCC
NEQVEAVVEVLVKSVEQSPAQIIMVSNEVGLGVVPLGKVSRLFVDNAGRMNQALARVVER
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEECHHHHHHHHHCCCCHHHHHHHHHHHH
VTLVAAGLPLSLKPSSYLTQSSTHN
HHHHHCCCCCEECCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]