Click here to switch to the map view.

The map label for this gene is cobC [C]

Identifier: 218709688

GI number: 218709688

Start: 1825578

End: 1826195

Strand: Reverse

Name: cobC [C]

Synonym: VS_1699

Alternate gene names: 218709688

Gene position: 1826195-1825578 (Counterclockwise)

Preceding gene: 218709689

Following gene: 218709687

Centisome position: 55.35

GC content: 43.53

Gene sequence:

>618_bases
ATGGAAAATGGAACAACCAAAAACATCTATCTACTAAGACATGGCAAAGTCGAAGGCGAAGCGGCACTTAATGGTTCATC
TGATGTGTTGGTTAATCCTGATCTTCAAGATCGGATATGTGGGGCGCTGATAAAACAAGATATTGCCTTTGATTGCGTGG
TTACTTCGCCATTAAGGCGATGCAGTGATCTCGCAAACAAATACGCACAGCGTATGTCTGTGCCTTTGTCTGTTGCACCA
GACTTTCAGGAAATGAACTTCGGTGACGTTGATGGTGTCCCATTTGATGAGCTTGAAGACAAGTGGGGGATGCTAGAAAC
CTTTTGGCAAGATCCTGCTAATCATCAACTGACTGGTGCAGAAAGTTTACAGAGCTTCCACGACAGAGTAACTCAAGCTT
GGTCGCAACTTTTGGACGATCCAAGTGACAATCTATTATTGGTTACTCATGGTGGTGTGATTCGCATATTGTTAGCGCAC
TGCCTTGATATCGATTGGAAAAATCCGAGTTTGTACTCGAAGCTATCGATAGAAAACGCATCGATAACTCATATTCAAAT
CACTCAGTTTGCGCAGAGCTTTACCAGTGTCAAATCGATAGGGCTACCTGTTCTCTGA

Upstream 100 bases:

>100_bases
CGCTGGTTGCTGCAGGATTACCATTGAGCTTAAAGCCGTCGAGCTATTTGACTCAAAGCTCGACTCATAATTAGATTGGT
ATCAAAGGTTAGTTGAACAA

Downstream 100 bases:

>100_bases
GTGTTCAAAAAACACAGTTTAAGAGTTAACAATCTATTGGACCTGTAAATAGAAATTGAAACAGAAATAGAAATAGAAAT
AGAAATAGAACCAGAAACAG

Product: fructose-2,6-bisphosphatase

Products: alpha-ribazole; phosphate

Alternate protein names: Alpha-Ribazole-5-Phosphate Phosphatase; Alpha-Ribazole Phosphatase; Fructose-2 6-Bisphosphatase; Alpha-Ribazole-5`-Phosphate Phosphatase CobC; Phosphoglycerate/Bisphosphoglycerate Mutase; Phosphoglycerate Mutase Family Protein; Phosphoglycerate Mutase/Fructose-2 6-Bisphosphatase; Bifunctional RNAse H/Acid Phosphatase; Alpha-Ribazole-5-Phosphate Phosphatase CobC; Phosphoglycerate Mutase Domain Protein; Enzymatic Protein; Fructose-26-Bisphosphatase; Alpha-Ribazole-5-Phosphate Phosphatase Protein; Phosphoglycerate Mutase 2 Protein; 7 Alpha-Ribazole-5-Phosphate Phosphatase; Alpha-Ribazole-5-P Phosphatase; Phosphoglycerate Mutase Family; Phosphoglycerate Mutase Gpmb

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MENGTTKNIYLLRHGKVEGEAALNGSSDVLVNPDLQDRICGALIKQDIAFDCVVTSPLRRCSDLANKYAQRMSVPLSVAP
DFQEMNFGDVDGVPFDELEDKWGMLETFWQDPANHQLTGAESLQSFHDRVTQAWSQLLDDPSDNLLLVTHGGVIRILLAH
CLDIDWKNPSLYSKLSIENASITHIQITQFAQSFTSVKSIGLPVL

Sequences:

>Translated_205_residues
MENGTTKNIYLLRHGKVEGEAALNGSSDVLVNPDLQDRICGALIKQDIAFDCVVTSPLRRCSDLANKYAQRMSVPLSVAP
DFQEMNFGDVDGVPFDELEDKWGMLETFWQDPANHQLTGAESLQSFHDRVTQAWSQLLDDPSDNLLLVTHGGVIRILLAH
CLDIDWKNPSLYSKLSIENASITHIQITQFAQSFTSVKSIGLPVL
>Mature_205_residues
MENGTTKNIYLLRHGKVEGEAALNGSSDVLVNPDLQDRICGALIKQDIAFDCVVTSPLRRCSDLANKYAQRMSVPLSVAP
DFQEMNFGDVDGVPFDELEDKWGMLETFWQDPANHQLTGAESLQSFHDRVTQAWSQLLDDPSDNLLLVTHGGVIRILLAH
CLDIDWKNPSLYSKLSIENASITHIQITQFAQSFTSVKSIGLPVL

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.3.73

Molecular weight: Translated: 22770; Mature: 22770

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENGTTKNIYLLRHGKVEGEAALNGSSDVLVNPDLQDRICGALIKQDIAFDCVVTSPLRR
CCCCCCCEEEEEECCCCCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHEEHHHHHHH
CSDLANKYAQRMSVPLSVAPDFQEMNFGDVDGVPFDELEDKWGMLETFWQDPANHQLTGA
HHHHHHHHHHHHCCCCEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCH
ESLQSFHDRVTQAWSQLLDDPSDNLLLVTHGGVIRILLAHCLDIDWKNPSLYSKLSIENA
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCHHEEECCCC
SITHIQITQFAQSFTSVKSIGLPVL
EEEEEHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MENGTTKNIYLLRHGKVEGEAALNGSSDVLVNPDLQDRICGALIKQDIAFDCVVTSPLRR
CCCCCCCEEEEEECCCCCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHEEHHHHHHH
CSDLANKYAQRMSVPLSVAPDFQEMNFGDVDGVPFDELEDKWGMLETFWQDPANHQLTGA
HHHHHHHHHHHHCCCCEECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCH
ESLQSFHDRVTQAWSQLLDDPSDNLLLVTHGGVIRILLAHCLDIDWKNPSLYSKLSIENA
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCHHEEECCCC
SITHIQITQFAQSFTSVKSIGLPVL
EEEEEHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alpha-ribazole 5'-phosphate; H2O

Specific reaction: alpha-ribazole 5'-phosphate + H2O = alpha-ribazole + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA