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The map label for this gene is uspA [H]

Identifier: 218709608

GI number: 218709608

Start: 1734211

End: 1734633

Strand: Direct

Name: uspA [H]

Synonym: VS_1618

Alternate gene names: 218709608

Gene position: 1734211-1734633 (Clockwise)

Preceding gene: 218709604

Following gene: 218709609

Centisome position: 52.56

GC content: 43.26

Gene sequence:

>423_bases
ATGGAATACCGACATATTCTGGTCGCTGTTGAAATGTCCGACGACACTAAGATTCTGATTGATCGAGCGACCTTCTTCGC
AAACAAACTAGAGGCTGGCATTTCGTTTGTTTATATCGACGGCACGCATGGCGAGATTTACCCTGAACTCGTTGATATTC
AGGGAAATGAAGGCGATCTACCCATCAATGAAGATTCCGTTAAGCATTTGAAAGAGTTTGAGGCGTACGCCAAGCACCCA
ATCAAGCACATATTCGTGGGAACGGGAGATTTGAATGATAAGCTCAAAAATACCATCGAGGTAAATGGCGTTGACCTACT
ACTATGTGGCCATCACCACGATTTTTGGCATAAAATCATTTCCCATTCGAAACAGATCATCGACACATCTCCAGTCGATA
TTCTAATCGTTCCAATGGATTAG

Upstream 100 bases:

>100_bases
TCATTGAATGATGATTTTATGCAATATGAGATCTCTTCGATATCATTTGTGCTAACAAAAACTATGCTTGTTATATAACT
GATAACATGAGGCTTTAATT

Downstream 100 bases:

>100_bases
ATACTGCCGTTCGAACTTTAAAAACTTCTGCATTGCCAATCTCTATCGGTATTATTGGTTGGCTTACATCCCCTCTTATT
TGCCCCAACCCAACTGTCAC

Product: universal stress protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MEYRHILVAVEMSDDTKILIDRATFFANKLEAGISFVYIDGTHGEIYPELVDIQGNEGDLPINEDSVKHLKEFEAYAKHP
IKHIFVGTGDLNDKLKNTIEVNGVDLLLCGHHHDFWHKIISHSKQIIDTSPVDILIVPMD

Sequences:

>Translated_140_residues
MEYRHILVAVEMSDDTKILIDRATFFANKLEAGISFVYIDGTHGEIYPELVDIQGNEGDLPINEDSVKHLKEFEAYAKHP
IKHIFVGTGDLNDKLKNTIEVNGVDLLLCGHHHDFWHKIISHSKQIIDTSPVDILIVPMD
>Mature_140_residues
MEYRHILVAVEMSDDTKILIDRATFFANKLEAGISFVYIDGTHGEIYPELVDIQGNEGDLPINEDSVKHLKEFEAYAKHP
IKHIFVGTGDLNDKLKNTIEVNGVDLLLCGHHHDFWHKIISHSKQIIDTSPVDILIVPMD

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1789909, Length=139, Percent_Identity=36.6906474820144, Blast_Score=112, Evalue=9e-27,
Organism=Escherichia coli, GI1790358, Length=146, Percent_Identity=26.027397260274, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788205, Length=140, Percent_Identity=26.4285714285714, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 290 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4003 Molecules/Cell In: Growth Phase, G

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 15873; Mature: 15873

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRHILVAVEMSDDTKILIDRATFFANKLEAGISFVYIDGTHGEIYPELVDIQGNEGDL
CCCEEEEEEEEECCCCEEEEEHHHHHHHHHCCCEEEEEEECCCCEECEEEEEEECCCCCC
PINEDSVKHLKEFEAYAKHPIKHIFVGTGDLNDKLKNTIEVNGVDLLLCGHHHDFWHKII
CCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHCEEEECCEEEEEECCCCHHHHHHH
SHSKQIIDTSPVDILIVPMD
HCCCCEECCCCCEEEEEECC
>Mature Secondary Structure
MEYRHILVAVEMSDDTKILIDRATFFANKLEAGISFVYIDGTHGEIYPELVDIQGNEGDL
CCCEEEEEEEEECCCCEEEEEHHHHHHHHHCCCEEEEEEECCCCEECEEEEEEECCCCCC
PINEDSVKHLKEFEAYAKHPIKHIFVGTGDLNDKLKNTIEVNGVDLLLCGHHHDFWHKII
CCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHCEEEECCEEEEEECCCCHHHHHHH
SHSKQIIDTSPVDILIVPMD
HCCCCEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]