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The map label for this gene is gltS [H]

Identifier: 218709560

GI number: 218709560

Start: 1703169

End: 1704392

Strand: Direct

Name: gltS [H]

Synonym: VS_1570

Alternate gene names: 218709560

Gene position: 1703169-1704392 (Clockwise)

Preceding gene: 218709559

Following gene: 218709564

Centisome position: 51.62

GC content: 45.75

Gene sequence:

>1224_bases
ATGGAATTTGAAAACAACATCTTACATCTCGGGTCATTCTTTGCTGTGACCATGGGGATCGTGGTTCTATTTATCGGGCG
AAGGCTGAATCAAGTTATCGGTTTTTTGAAAGAGTTCAGTATCCCTGAACCTGTCTCTGGCGGGATTTTAGCATCGCTCT
TGTTCGCGGTTTTATACGCGACGACCTCAATCGAAGTGCAATTTGATCTATTTGCCCGCGATGTATTATTGGTCTACTTC
TTTACCACGATTGGGATTAACTCAAGTTTGAAAGACCTGTTCAAAGGCGGAAAGCCCTTGGTGATTTTGCTATCAATCAC
TATCTTCTTCATGATCATGCAGAACATCGTCGGTATTTCTGTCGCATCAATGTTTGGCCTAGAGCCTGTCTTTGGCCTGC
TCAGCGGAAGTATTTCACTGATTGGCGGACATGGTACCGCGATTGCTTGGGCACCCAAGGTTGCAGGAGAGTTCGGCCTA
GAAAGCGCAATGGAAATTGGTATCGCCAGTGCAACATTTGGGCTGATTTTAGCCAGCCTGATGGGTGGCCCTATTGCAAA
GTTTCTCATTAAGCGTCACAACCTCAAACCTACCGATGAGCAATCAAACTCAATCGATTCAAATGCAAAAAAACAACACC
AAGCTCTTACATCATTTCAATTTTTAGACGCCGTGTTAGCGATTCATATTTGTGTCATTGTCGGCGCGTTGCTTAATGAA
TTGATCAGTCAAACCGGGTTACAGCTTCCACTGTTTGTATCGTGTTTGTTTGCAGGTATCGTGATCACCAACGTAATGCC
AGACTCCTACCCTAGAATCTCGGGTGCAAAATGGCCGACACGCTCGCCCGCTATCGACTTAATTGCTGAAATCTCCCTGG
GTACATTTTTGGCGATGTCACTAATGAGCATGCAGCTTTGGACGCTCATTGACTTGGCGGGTCCTATCTTCGCGATATTG
GCAATGCAGCTGCTACTCGCGGTGATAATCAATATCTTCATCGTGTTCCCATCAATGGGTAAAACCTATGATGCGGCTGT
TGTATGTGCTGGGTTCGGAGGGATTTCGTTAGGTTCAACACCGACAGCCATGGCAAACATGTCGGCAGTAAGTCAGAAGT
ATGGGCATTCAGCACAAGCCTTCATCATCGTGCCATTGGTATGCGCGTTCTTCATTGATTTAGCGAACGCCCTGATTATT
CCTTACTTCATGAGAATGATGTAG

Upstream 100 bases:

>100_bases
TTATCATTTGAACGCAACAAATAATGCTAATCTAGTTGCTTATTAAAGCGCAATTTGGCAACTAAAGTTACGTCATAACT
TCACCTTTACAAGGATCACT

Downstream 100 bases:

>100_bases
CTGACCTCTGTTAATACGATATTCCACAATTTGTTCGGTGTACCGCAATTTATTTAGGCGGTGTACCCCAATAAAAAGAG
CCGCTCAATACAGAGCGACT

Product: putative glutamate permease

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MEFENNILHLGSFFAVTMGIVVLFIGRRLNQVIGFLKEFSIPEPVSGGILASLLFAVLYATTSIEVQFDLFARDVLLVYF
FTTIGINSSLKDLFKGGKPLVILLSITIFFMIMQNIVGISVASMFGLEPVFGLLSGSISLIGGHGTAIAWAPKVAGEFGL
ESAMEIGIASATFGLILASLMGGPIAKFLIKRHNLKPTDEQSNSIDSNAKKQHQALTSFQFLDAVLAIHICVIVGALLNE
LISQTGLQLPLFVSCLFAGIVITNVMPDSYPRISGAKWPTRSPAIDLIAEISLGTFLAMSLMSMQLWTLIDLAGPIFAIL
AMQLLLAVIINIFIVFPSMGKTYDAAVVCAGFGGISLGSTPTAMANMSAVSQKYGHSAQAFIIVPLVCAFFIDLANALII
PYFMRMM

Sequences:

>Translated_407_residues
MEFENNILHLGSFFAVTMGIVVLFIGRRLNQVIGFLKEFSIPEPVSGGILASLLFAVLYATTSIEVQFDLFARDVLLVYF
FTTIGINSSLKDLFKGGKPLVILLSITIFFMIMQNIVGISVASMFGLEPVFGLLSGSISLIGGHGTAIAWAPKVAGEFGL
ESAMEIGIASATFGLILASLMGGPIAKFLIKRHNLKPTDEQSNSIDSNAKKQHQALTSFQFLDAVLAIHICVIVGALLNE
LISQTGLQLPLFVSCLFAGIVITNVMPDSYPRISGAKWPTRSPAIDLIAEISLGTFLAMSLMSMQLWTLIDLAGPIFAIL
AMQLLLAVIINIFIVFPSMGKTYDAAVVCAGFGGISLGSTPTAMANMSAVSQKYGHSAQAFIIVPLVCAFFIDLANALII
PYFMRMM
>Mature_407_residues
MEFENNILHLGSFFAVTMGIVVLFIGRRLNQVIGFLKEFSIPEPVSGGILASLLFAVLYATTSIEVQFDLFARDVLLVYF
FTTIGINSSLKDLFKGGKPLVILLSITIFFMIMQNIVGISVASMFGLEPVFGLLSGSISLIGGHGTAIAWAPKVAGEFGL
ESAMEIGIASATFGLILASLMGGPIAKFLIKRHNLKPTDEQSNSIDSNAKKQHQALTSFQFLDAVLAIHICVIVGALLNE
LISQTGLQLPLFVSCLFAGIVITNVMPDSYPRISGAKWPTRSPAIDLIAEISLGTFLAMSLMSMQLWTLIDLAGPIFAIL
AMQLLLAVIINIFIVFPSMGKTYDAAVVCAGFGGISLGSTPTAMANMSAVSQKYGHSAQAFIIVPLVCAFFIDLANALII
PYFMRMM

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=382, Percent_Identity=41.0994764397906, Blast_Score=268, Evalue=4e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 43681; Mature: 43681

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFENNILHLGSFFAVTMGIVVLFIGRRLNQVIGFLKEFSIPEPVSGGILASLLFAVLYA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TTSIEVQFDLFARDVLLVYFFTTIGINSSLKDLFKGGKPLVILLSITIFFMIMQNIVGIS
HHHEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHH
VASMFGLEPVFGLLSGSISLIGGHGTAIAWAPKVAGEFGLESAMEIGIASATFGLILASL
HHHHHCHHHHHHHHCCCEEEEECCCCEEEECHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
MGGPIAKFLIKRHNLKPTDEQSNSIDSNAKKQHQALTSFQFLDAVLAIHICVIVGALLNE
HCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISQTGLQLPLFVSCLFAGIVITNVMPDSYPRISGAKWPTRSPAIDLIAEISLGTFLAMS
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LMSMQLWTLIDLAGPIFAILAMQLLLAVIINIFIVFPSMGKTYDAAVVCAGFGGISLGST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEECCCCCCCCCC
PTAMANMSAVSQKYGHSAQAFIIVPLVCAFFIDLANALIIPYFMRMM
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MEFENNILHLGSFFAVTMGIVVLFIGRRLNQVIGFLKEFSIPEPVSGGILASLLFAVLYA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TTSIEVQFDLFARDVLLVYFFTTIGINSSLKDLFKGGKPLVILLSITIFFMIMQNIVGIS
HHHEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHH
VASMFGLEPVFGLLSGSISLIGGHGTAIAWAPKVAGEFGLESAMEIGIASATFGLILASL
HHHHHCHHHHHHHHCCCEEEEECCCCEEEECHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
MGGPIAKFLIKRHNLKPTDEQSNSIDSNAKKQHQALTSFQFLDAVLAIHICVIVGALLNE
HCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISQTGLQLPLFVSCLFAGIVITNVMPDSYPRISGAKWPTRSPAIDLIAEISLGTFLAMS
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LMSMQLWTLIDLAGPIFAILAMQLLLAVIINIFIVFPSMGKTYDAAVVCAGFGGISLGST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEECCCCCCCCCC
PTAMANMSAVSQKYGHSAQAFIIVPLVCAFFIDLANALIIPYFMRMM
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]