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The map label for this gene is srpC [H]

Identifier: 218709532

GI number: 218709532

Start: 1680738

End: 1682246

Strand: Direct

Name: srpC [H]

Synonym: VS_1541

Alternate gene names: 218709532

Gene position: 1680738-1682246 (Clockwise)

Preceding gene: 218709531

Following gene: 218709540

Centisome position: 50.94

GC content: 49.37

Gene sequence:

>1509_bases
ATGCGTCCATTAACTAAGTTTAAAGTCGCTCCTATAGCGCTCGCTTTGTTGCTGACAGGTTGTGCTGTTGGCCCAGATTA
CGAAGAACCGCAAACGACCATGGCAGAGACGTTCTTATATAGCCAAGGTGATGTGAGCCAAGACGGCGTGAGCCAAAACG
AACAGCACAACCATTGGTGGACACAGTTCAATGATCCCACGCTCAATCAGTTAGTGGCCGATGTTCAAAGCCAGAACATC
CCACTTAAACTGGCAGCCGAGCGAATCAACATGGCGAACTCATACAAAAGCGTGGTCGAATCATTCAAGGTTCCGACCAT
TAACGTCGGTGGTGGTTATTACAACTACCAACTGAGTGAGAACGACTCCCTACTCGGCCCGGTATTTGGTGCCTCTGATG
CGGTTGAGTCAGCAACGGGCATGTCGTTGCTGGAAGCTCAACACGATGGTGGATTCTTAGGTGCGAGCATCGCGTGGGAA
ATGGACTTGTTTGGACGTATCGACAAACAATCCAACGCAGCGACGATTCGAGTTGAACAAGCCGAGATATTCCAATCAGG
CTTGAACACCTTGATCACTGCCGATGTCATTCACAACTACCTGCAATATCGTGGCGCGCAAGAGCGAAAAATGATCGCAC
TAGAGAACATAGCCGACCAAAAGCAGACTTTAGAATTGGTCACCAAAGTGGTTCGCAGCGGCTACGGGTCTGAGTTAGAT
CTTGCTCAAGCCAAAGCCATGCTTGCGGCGACTGAATCTATTGTTCCTCAACTTGAAATAGCAGAGCAAGTTCACAAACA
ACGCATGGCAGTTCTGTTAGGCGAATCACTCACGAGCGTAAACCAACGTTTAGTCGGTGAATTCACTCTTCCGCGAATGA
ACGATGTAATTCCGACAGGCTTACCTTCTGACTTATTAGAACAACGCCCAGATATCCGAATCGCAGAACGCGAAATGGCA
GCCATTAACGAAGAACTTGGTGCAAGCATTGCTAATCGCTATCCAAAGTTCTTCCTAACGGGTACGCCCGGTGTGACGGC
TGGAAGCTTTGATGATCTGTTCAGTAGCGACTCATTCGGTTGGGCGGCATCTGCCGGTATCAGTTGGAATGTATTCGATG
GTGGCCGAGGCGAAGCCATAGTGGAAATGAACGAAGCAAGGTTCCGTTCTGCAGCGCTTAACTACCAACACTCTGTCGAC
AGCGCCTTTGCAGAAGTCGATTCAAGCTTGTTTGCCTATGGCCGTAGCCAAGAGAACCAAAAGCGCATCGATGAAGCTAC
CCTTGCCGTTGATAACGCGGTGAGCAAGGCAAAGTCGCTATACAAAGCGGGGCTAGTCGATTACTTGTCGGTGTTAGACG
CACAAAGACAACAAAAAGCGATGCAAGATCGCCAAGTAGCCGCCAAGCTTCAAACCGCCAACACCACGATTGCGGTGTAT
AAAGCCTTAGGTGGAGATTGGAAAGTGGCGAACGAAACGCAGAGTGTCGAATTAGCTCACGTTAACTAG

Upstream 100 bases:

>100_bases
CAGTAGCAGAAGCAATCAAAGACGCCGTGATTGTGCTTGATGCAACACCTCAGCATTCAAACAGCGGAAATACAACTTCA
TTCAACAAGGAGCAATAAAC

Downstream 100 bases:

>100_bases
TCTTTCTGCTCTATGTTCTCTGCTGAATGTTCTTTGTTCTGTAGTGAATGATGTAATAAACGTAATAAAAAATACCGCCG
TTGATTACGGCGGTATTTTT

Product: putative efflux pump outer membrane

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MRPLTKFKVAPIALALLLTGCAVGPDYEEPQTTMAETFLYSQGDVSQDGVSQNEQHNHWWTQFNDPTLNQLVADVQSQNI
PLKLAAERINMANSYKSVVESFKVPTINVGGGYYNYQLSENDSLLGPVFGASDAVESATGMSLLEAQHDGGFLGASIAWE
MDLFGRIDKQSNAATIRVEQAEIFQSGLNTLITADVIHNYLQYRGAQERKMIALENIADQKQTLELVTKVVRSGYGSELD
LAQAKAMLAATESIVPQLEIAEQVHKQRMAVLLGESLTSVNQRLVGEFTLPRMNDVIPTGLPSDLLEQRPDIRIAEREMA
AINEELGASIANRYPKFFLTGTPGVTAGSFDDLFSSDSFGWAASAGISWNVFDGGRGEAIVEMNEARFRSAALNYQHSVD
SAFAEVDSSLFAYGRSQENQKRIDEATLAVDNAVSKAKSLYKAGLVDYLSVLDAQRQQKAMQDRQVAAKLQTANTTIAVY
KALGGDWKVANETQSVELAHVN

Sequences:

>Translated_502_residues
MRPLTKFKVAPIALALLLTGCAVGPDYEEPQTTMAETFLYSQGDVSQDGVSQNEQHNHWWTQFNDPTLNQLVADVQSQNI
PLKLAAERINMANSYKSVVESFKVPTINVGGGYYNYQLSENDSLLGPVFGASDAVESATGMSLLEAQHDGGFLGASIAWE
MDLFGRIDKQSNAATIRVEQAEIFQSGLNTLITADVIHNYLQYRGAQERKMIALENIADQKQTLELVTKVVRSGYGSELD
LAQAKAMLAATESIVPQLEIAEQVHKQRMAVLLGESLTSVNQRLVGEFTLPRMNDVIPTGLPSDLLEQRPDIRIAEREMA
AINEELGASIANRYPKFFLTGTPGVTAGSFDDLFSSDSFGWAASAGISWNVFDGGRGEAIVEMNEARFRSAALNYQHSVD
SAFAEVDSSLFAYGRSQENQKRIDEATLAVDNAVSKAKSLYKAGLVDYLSVLDAQRQQKAMQDRQVAAKLQTANTTIAVY
KALGGDWKVANETQSVELAHVN
>Mature_502_residues
MRPLTKFKVAPIALALLLTGCAVGPDYEEPQTTMAETFLYSQGDVSQDGVSQNEQHNHWWTQFNDPTLNQLVADVQSQNI
PLKLAAERINMANSYKSVVESFKVPTINVGGGYYNYQLSENDSLLGPVFGASDAVESATGMSLLEAQHDGGFLGASIAWE
MDLFGRIDKQSNAATIRVEQAEIFQSGLNTLITADVIHNYLQYRGAQERKMIALENIADQKQTLELVTKVVRSGYGSELD
LAQAKAMLAATESIVPQLEIAEQVHKQRMAVLLGESLTSVNQRLVGEFTLPRMNDVIPTGLPSDLLEQRPDIRIAEREMA
AINEELGASIANRYPKFFLTGTPGVTAGSFDDLFSSDSFGWAASAGISWNVFDGGRGEAIVEMNEARFRSAALNYQHSVD
SAFAEVDSSLFAYGRSQENQKRIDEATLAVDNAVSKAKSLYKAGLVDYLSVLDAQRQQKAMQDRQVAAKLQTANTTIAVY
KALGGDWKVANETQSVELAHVN

Specific function: The outer membrane component of an organic solvent efflux pump. Involved in export of a number of low log POW compounds including hexane (log POW 3.5), toluene (log POW 2.5) and dimethylphthalate (log POW 2.3). The solvent resistance phenotype has been po

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=491, Percent_Identity=27.4949083503055, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 54879; Mature: 54879

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLTKFKVAPIALALLLTGCAVGPDYEEPQTTMAETFLYSQGDVSQDGVSQNEQHNHWW
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
TQFNDPTLNQLVADVQSQNIPLKLAAERINMANSYKSVVESFKVPTINVGGGYYNYQLSE
CCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECC
NDSLLGPVFGASDAVESATGMSLLEAQHDGGFLGASIAWEMDLFGRIDKQSNAATIRVEQ
CCCCCCCCCCCCHHHHHHCCHHHHHHCCCCCEECCCEEEEHHHHHCCCCCCCCEEEEEHH
AEIFQSGLNTLITADVIHNYLQYRGAQERKMIALENIADQKQTLELVTKVVRSGYGSELD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
LAQAKAMLAATESIVPQLEIAEQVHKQRMAVLLGESLTSVNQRLVGEFTLPRMNDVIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCC
LPSDLLEQRPDIRIAEREMAAINEELGASIANRYPKFFLTGTPGVTAGSFDDLFSSDSFG
CCHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHCCCCCC
WAASAGISWNVFDGGRGEAIVEMNEARFRSAALNYQHSVDSAFAEVDSSLFAYGRSQENQ
CEEECCCEEEECCCCCCCEEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHH
KRIDEATLAVDNAVSKAKSLYKAGLVDYLSVLDAQRQQKAMQDRQVAAKLQTANTTIAVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
KALGGDWKVANETQSVELAHVN
ECCCCCEEECCCCCCEEEEECC
>Mature Secondary Structure
MRPLTKFKVAPIALALLLTGCAVGPDYEEPQTTMAETFLYSQGDVSQDGVSQNEQHNHWW
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
TQFNDPTLNQLVADVQSQNIPLKLAAERINMANSYKSVVESFKVPTINVGGGYYNYQLSE
CCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECC
NDSLLGPVFGASDAVESATGMSLLEAQHDGGFLGASIAWEMDLFGRIDKQSNAATIRVEQ
CCCCCCCCCCCCHHHHHHCCHHHHHHCCCCCEECCCEEEEHHHHHCCCCCCCCEEEEEHH
AEIFQSGLNTLITADVIHNYLQYRGAQERKMIALENIADQKQTLELVTKVVRSGYGSELD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
LAQAKAMLAATESIVPQLEIAEQVHKQRMAVLLGESLTSVNQRLVGEFTLPRMNDVIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCC
LPSDLLEQRPDIRIAEREMAAINEELGASIANRYPKFFLTGTPGVTAGSFDDLFSSDSFG
CCHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHCCCCCC
WAASAGISWNVFDGGRGEAIVEMNEARFRSAALNYQHSVDSAFAEVDSSLFAYGRSQENQ
CEEECCCEEEECCCCCCCEEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHH
KRIDEATLAVDNAVSKAKSLYKAGLVDYLSVLDAQRQQKAMQDRQVAAKLQTANTTIAVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
KALGGDWKVANETQSVELAHVN
ECCCCCEEECCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9417051; 9852029 [H]