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The map label for this gene is atoS [H]

Identifier: 218709488

GI number: 218709488

Start: 1630512

End: 1632539

Strand: Reverse

Name: atoS [H]

Synonym: VS_1497

Alternate gene names: 218709488

Gene position: 1632539-1630512 (Counterclockwise)

Preceding gene: 218709489

Following gene: 218709485

Centisome position: 49.48

GC content: 43.84

Gene sequence:

>2028_bases
ATGCCGATTAGACGTCATTGGTGGTCAAAGTGGACGTTTCGGTTCAAAACCATGGTGCGTTATCGTCTGTTATTTTTGAC
GTCAGCGCCGATCATCTTAACTTTATGCGCTCTGGTTGCGATCACTTTGTATTGGTCTGTTCATTATACGTGGCAGGGGG
CTTTGATCGATGTTGATGAGCGTTTGGACGTTGCCGACAACAGTATCCATCTAATTCAAAACCAACAGGCCTATAACGTT
CAAGCATTCGCTGAGTCTTATAACTTTCGAGTTAAACTTACGAGTGATATTTCAAAGGAAGAGCTCACTCGTTGGGTTTC
TGAAAACAAATCTCGCTATGAGCTCGACTTTTTGCGTTGGAGAAGTGTTGAGAGCATGGAGAAAAAACTTGAATACCTCA
ACCTGACACACAAAGAATCGTTCTTTAGTGTATTGAGCCAAAACGAACTCAACGATTTAGACCAAAACCTTGCTAGGCAA
GCCGAAGTTCCAATGCTCAATAGTCAAAACGTTGAAACTCGGGGTTTAGTTAGCCGAACTGTTGTGTCAATTAGAGACAA
GAATGATCACGTTATTGGTTTTCTTGATGGCGGGATCCTACTTAACAACAGCACACAGTTAGTTGATCAGATCAGCAATT
TGATCTATCCACAACGTGATGGTTTTAATCGCCGCATAGGTACCGTCACTGTGTTCCTTGATGACCTACGTGTCAGCACT
AATGTACCGTTGAGCAGTGAAGACAGTGCAGGGCGCGCAATTGGTACTCGCGTTTCTCATGAGGTTCATTCAAAAGTATT
GAATCAAGGGCAAAAGTGGTTAGACCGAGCATATGTTTACGACGCTTGGTACATCACCGCTTACCAACCAATCCACGACC
AGTTTGATAACGTTATTGGCATGCTTTATACCGGCTATCTAATCTGGCCACTCGTAGAGACGTATCTGACTAACCTTGGT
GAAATCAGCATCACCATCATATTACTGCTGTTAGCTTCAGGTTTGATCGTACACCGTGGTGCTCGCGATCTTTTCAACCC
AATTGAACGCATCCATAAAGTCGTAAAGCTCGTCCAAATGGGGCAAGACAAGCGAATCGGTACGTTGGGTTTGGATGATC
AACACGAACTTACGTTGCTTGCGAAACAGTTCGACAAAATGTTAGATCTGCTCCACGAGCGTAATCAAGAGATTCAACAA
GCTGCGTCTGAACTCGAATGTAAGGTTCATTCTCGTACCGCCAGTTTGAAAGAGAAAACGGAAGAACTCGAACTGCACAT
CCAGCTTCTTAACCAAGCTAGAGATAAGCTGGTGGTCAACGAAAAATTAGCCGCGTTAGGTGAGTTAACCGCAGGTATTG
CCCATGAAATCAATAATCCGACAGCAGTAATTCTAGGCAATGTTGAACTAATGAAGTTTGAACTCGGCGATGAAGTGGCT
CGTGTAGACGAAGAAGTCCACGCGATCATGGAGCAGATCGACCGAATCCGAAACATCACACGAAGCTTACTTCAATACAG
CCGACACGGTGGTGTACAAGACGAAATTACTTGGCAACATATCAATCCAATTGTCGATGAAAGTATTACGCTCGTAAAAA
CAGGCGCAAAAAAGAAAGGCATTGTGTATGTCTCGCAATTGAATGCTAAAACCTCAGTCGAAGTGAACCGAAACCAATTG
CTGCAAATTCTAGTGAACCTGCAAATGAACGCGATTCATGCCATGGACGGACAGGGCACATTGACTATCTCGAGTGAAGA
TTGGGTTGAAAATGGAGTATCTCATGGTGCGATCGTTCATGTTGAAGATGAGGGCTGTGGTATTAAGGAAGAACAACTGA
AACGTATATTCTCTCCTTTCTATACCACCAAAAGAGACGGTACAGGCTTAGGTTTGTCCGTTTCTCAAAGTATTTTGAGC
CAAACGGGCGGCGAAATACGAGTTGAATCCGAAGTAGGTAAGGGAAGTCGCTTTAGTATCTATCTTCAGCAAAAAGCCAC
ACCCCAGTTATTAGTGTCTAACCTTTAG

Upstream 100 bases:

>100_bases
TTTCATGATGGTAATAAATCCGCAGCTGCAAGAGACCTCGGCGTTGCACGGAAAACGCTAGAGCGTAAATATAAAGATTG
GAACACAGAAGGATCTGAAT

Downstream 100 bases:

>100_bases
TCGTTCATAACGCGAATAGAAAACACCTCCGTACTTAAGATAAGTTCGGAGGTGTTTTTATTTATGGCCGTTATTTCAAA
CGATTACGAGCGTCCAAAAC

Product: putative sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 675; Mature: 674

Protein sequence:

>675_residues
MPIRRHWWSKWTFRFKTMVRYRLLFLTSAPIILTLCALVAITLYWSVHYTWQGALIDVDERLDVADNSIHLIQNQQAYNV
QAFAESYNFRVKLTSDISKEELTRWVSENKSRYELDFLRWRSVESMEKKLEYLNLTHKESFFSVLSQNELNDLDQNLARQ
AEVPMLNSQNVETRGLVSRTVVSIRDKNDHVIGFLDGGILLNNSTQLVDQISNLIYPQRDGFNRRIGTVTVFLDDLRVST
NVPLSSEDSAGRAIGTRVSHEVHSKVLNQGQKWLDRAYVYDAWYITAYQPIHDQFDNVIGMLYTGYLIWPLVETYLTNLG
EISITIILLLLASGLIVHRGARDLFNPIERIHKVVKLVQMGQDKRIGTLGLDDQHELTLLAKQFDKMLDLLHERNQEIQQ
AASELECKVHSRTASLKEKTEELELHIQLLNQARDKLVVNEKLAALGELTAGIAHEINNPTAVILGNVELMKFELGDEVA
RVDEEVHAIMEQIDRIRNITRSLLQYSRHGGVQDEITWQHINPIVDESITLVKTGAKKKGIVYVSQLNAKTSVEVNRNQL
LQILVNLQMNAIHAMDGQGTLTISSEDWVENGVSHGAIVHVEDEGCGIKEEQLKRIFSPFYTTKRDGTGLGLSVSQSILS
QTGGEIRVESEVGKGSRFSIYLQQKATPQLLVSNL

Sequences:

>Translated_675_residues
MPIRRHWWSKWTFRFKTMVRYRLLFLTSAPIILTLCALVAITLYWSVHYTWQGALIDVDERLDVADNSIHLIQNQQAYNV
QAFAESYNFRVKLTSDISKEELTRWVSENKSRYELDFLRWRSVESMEKKLEYLNLTHKESFFSVLSQNELNDLDQNLARQ
AEVPMLNSQNVETRGLVSRTVVSIRDKNDHVIGFLDGGILLNNSTQLVDQISNLIYPQRDGFNRRIGTVTVFLDDLRVST
NVPLSSEDSAGRAIGTRVSHEVHSKVLNQGQKWLDRAYVYDAWYITAYQPIHDQFDNVIGMLYTGYLIWPLVETYLTNLG
EISITIILLLLASGLIVHRGARDLFNPIERIHKVVKLVQMGQDKRIGTLGLDDQHELTLLAKQFDKMLDLLHERNQEIQQ
AASELECKVHSRTASLKEKTEELELHIQLLNQARDKLVVNEKLAALGELTAGIAHEINNPTAVILGNVELMKFELGDEVA
RVDEEVHAIMEQIDRIRNITRSLLQYSRHGGVQDEITWQHINPIVDESITLVKTGAKKKGIVYVSQLNAKTSVEVNRNQL
LQILVNLQMNAIHAMDGQGTLTISSEDWVENGVSHGAIVHVEDEGCGIKEEQLKRIFSPFYTTKRDGTGLGLSVSQSILS
QTGGEIRVESEVGKGSRFSIYLQQKATPQLLVSNL
>Mature_674_residues
PIRRHWWSKWTFRFKTMVRYRLLFLTSAPIILTLCALVAITLYWSVHYTWQGALIDVDERLDVADNSIHLIQNQQAYNVQ
AFAESYNFRVKLTSDISKEELTRWVSENKSRYELDFLRWRSVESMEKKLEYLNLTHKESFFSVLSQNELNDLDQNLARQA
EVPMLNSQNVETRGLVSRTVVSIRDKNDHVIGFLDGGILLNNSTQLVDQISNLIYPQRDGFNRRIGTVTVFLDDLRVSTN
VPLSSEDSAGRAIGTRVSHEVHSKVLNQGQKWLDRAYVYDAWYITAYQPIHDQFDNVIGMLYTGYLIWPLVETYLTNLGE
ISITIILLLLASGLIVHRGARDLFNPIERIHKVVKLVQMGQDKRIGTLGLDDQHELTLLAKQFDKMLDLLHERNQEIQQA
ASELECKVHSRTASLKEKTEELELHIQLLNQARDKLVVNEKLAALGELTAGIAHEINNPTAVILGNVELMKFELGDEVAR
VDEEVHAIMEQIDRIRNITRSLLQYSRHGGVQDEITWQHINPIVDESITLVKTGAKKKGIVYVSQLNAKTSVEVNRNQLL
QILVNLQMNAIHAMDGQGTLTISSEDWVENGVSHGAIVHVEDEGCGIKEEQLKRIFSPFYTTKRDGTGLGLSVSQSILSQ
TGGEIRVESEVGKGSRFSIYLQQKATPQLLVSNL

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=36.0869565217391, Blast_Score=145, Evalue=9e-36,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=34.7457627118644, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786600, Length=252, Percent_Identity=27.7777777777778, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1789149, Length=442, Percent_Identity=24.4343891402715, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI87081816, Length=303, Percent_Identity=27.7227722772277, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790300, Length=221, Percent_Identity=28.9592760180996, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI145693157, Length=225, Percent_Identity=27.1111111111111, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=23.2456140350877, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=137, Percent_Identity=34.3065693430657, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76819; Mature: 76688

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRRHWWSKWTFRFKTMVRYRLLFLTSAPIILTLCALVAITLYWSVHYTWQGALIDVDE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEEEECEEEECCC
RLDVADNSIHLIQNQQAYNVQAFAESYNFRVKLTSDISKEELTRWVSENKSRYELDFLRW
CCCCCCCCEEEEECCCCCCHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCEEEHHHHH
RSVESMEKKLEYLNLTHKESFFSVLSQNELNDLDQNLARQAEVPMLNSQNVETRGLVSRT
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
VVSIRDKNDHVIGFLDGGILLNNSTQLVDQISNLIYPQRDGFNRRIGTVTVFLDDLRVST
HEEEECCCCCEEEEEECCEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECEEEEC
NVPLSSEDSAGRAIGTRVSHEVHSKVLNQGQKWLDRAYVYDAWYITAYQPIHDQFDNVIG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECHHHHHHHHHHH
MLYTGYLIWPLVETYLTNLGEISITIILLLLASGLIVHRGARDLFNPIERIHKVVKLVQM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHC
GQDKRIGTLGLDDQHELTLLAKQFDKMLDLLHERNQEIQQAASELECKVHSRTASLKEKT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EELELHIQLLNQARDKLVVNEKLAALGELTAGIAHEINNPTAVILGNVELMKFELGDEVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEEEEECCHHHH
RVDEEVHAIMEQIDRIRNITRSLLQYSRHGGVQDEITWQHINPIVDESITLVKTGAKKKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCHHHCCCEEEEECCCCCCC
IVYVSQLNAKTSVEVNRNQLLQILVNLQMNAIHAMDGQGTLTISSEDWVENGVSHGAIVH
EEEEEECCCCCEEEECHHHHHHHHHHHHHHEEEEECCCEEEEECCHHHHHCCCCCCEEEE
VEDEGCGIKEEQLKRIFSPFYTTKRDGTGLGLSVSQSILSQTGGEIRVESEVGKGSRFSI
ECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEE
YLQQKATPQLLVSNL
EEECCCCHHHHHCCC
>Mature Secondary Structure 
PIRRHWWSKWTFRFKTMVRYRLLFLTSAPIILTLCALVAITLYWSVHYTWQGALIDVDE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEEEECEEEECCC
RLDVADNSIHLIQNQQAYNVQAFAESYNFRVKLTSDISKEELTRWVSENKSRYELDFLRW
CCCCCCCCEEEEECCCCCCHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCEEEHHHHH
RSVESMEKKLEYLNLTHKESFFSVLSQNELNDLDQNLARQAEVPMLNSQNVETRGLVSRT
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
VVSIRDKNDHVIGFLDGGILLNNSTQLVDQISNLIYPQRDGFNRRIGTVTVFLDDLRVST
HEEEECCCCCEEEEEECCEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECEEEEC
NVPLSSEDSAGRAIGTRVSHEVHSKVLNQGQKWLDRAYVYDAWYITAYQPIHDQFDNVIG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECHHHHHHHHHHH
MLYTGYLIWPLVETYLTNLGEISITIILLLLASGLIVHRGARDLFNPIERIHKVVKLVQM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHC
GQDKRIGTLGLDDQHELTLLAKQFDKMLDLLHERNQEIQQAASELECKVHSRTASLKEKT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EELELHIQLLNQARDKLVVNEKLAALGELTAGIAHEINNPTAVILGNVELMKFELGDEVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEEEEECCHHHH
RVDEEVHAIMEQIDRIRNITRSLLQYSRHGGVQDEITWQHINPIVDESITLVKTGAKKKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCHHHCCCEEEEECCCCCCC
IVYVSQLNAKTSVEVNRNQLLQILVNLQMNAIHAMDGQGTLTISSEDWVENGVSHGAIVH
EEEEEECCCCCEEEECHHHHHHHHHHHHHHEEEEECCCEEEEECCHHHHHCCCCCCEEEE
VEDEGCGIKEEQLKRIFSPFYTTKRDGTGLGLSVSQSILSQTGGEIRVESEVGKGSRFSI
ECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEE
YLQQKATPQLLVSNL
EEECCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]